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Editor: Nathalie Le Bot
Editor: Nathalie Le Bot
Editor: Nathalie Le Bot
Series handle: RePEc:nat:natcom
ISSN: 2041-1723

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Content

December 2024, Volume 15, Issue 1

1-20 DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts
by Mariana Shumliakivska & Guillermo Luxán & Inga Hemmerling & Marina Scheller & Xue Li & Carsten Müller-Tidow & Bianca Schuhmacher & Zhengwu Sun & Andreas Dendorfer & Alisa Debes & Simone-Franziska Glaser & Marion Muhly-Reinholz & Klara Kirschbaum & Jedrzej Hoffmann & Eike Nagel & Valentina O. Puntmann & Sebastian Cremer & Florian Leuschner & Wesley Tyler Abplanalp & David John & Andreas M. Zeiher & Stefanie Dimmeler
1-20 AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis
by Taiqi Chen & Siyi Xie & Jie Cheng & Qiao Zhao & Hong Wu & Peng Jiang & Wenjing Du
1-20 Siglec-6 as a therapeutic target for cell migration and adhesion in chronic lymphocytic leukemia
by Jessica Nunes & Rakeb Tafesse & Charlene Mao & Matthew Purcell & Xiaokui Mo & Liwen Zhang & Meixiao Long & Matthew G. Cyr & Christoph Rader & Natarajan Muthusamy
1-20 Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons
by Beatriz del Blanco & Sergio Niñerola & Ana M. Martín-González & Juan Paraíso-Luna & Minji Kim & Rafael Muñoz-Viana & Carina Racovac & Jose V. Sanchez-Mut & Yijun Ruan & Ángel Barco
1-20 Glypican-3-targeted macrophages delivering drug-loaded exosomes offer efficient cytotherapy in mouse models of solid tumours
by Jinhu Liu & Huajun Zhao & Tong Gao & Xinyan Huang & Shujun Liu & Meichen Liu & Weiwei Mu & Shuang Liang & Shunli Fu & Shijun Yuan & Qinglin Yang & Panpan Gu & Nan Li & Qingping Ma & Jie Liu & Xinke Zhang & Na Zhang & Yongjun Liu
1-20 An output-null signature of inertial load in motor cortex
by Eric A. Kirk & Keenan T. Hope & Samuel J. Sober & Britton A. Sauerbrei
1-20 SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex
by Liangguang Leo Lin & Huilun Helen Wang & Brent Pederson & Xiaoqiong Wei & Mauricio Torres & You Lu & Zexin Jason Li & Xiaodan Liu & Hancheng Mao & Hui Wang & Linyao Elina Zhou & Zhen Zhao & Shengyi Sun & Ling Qi
1-20 VSV∆M51 drives CD8+ T cell-mediated tumour regression through infection of both cancer and non-cancer cells
by Jahanara Rajwani & Daniil Vishnevskiy & Madison Turk & Victor Naumenko & Chris Gafuik & Dae-Sun Kim & Laura K. Mah & Shannon Snelling & Gerone A. Gonzales & Jingna Xue & Ayan Chanda & Kyle G. Potts & Hayley M. Todesco & Keith C. K. Lau & Karys M. Hildebrand & Jennifer A. Chan & Shan Liao & Michael J. Monument & Martin Hyrcza & Pinaki Bose & Craig N. Jenne & Johnathan Canton & Franz J. Zemp & Douglas J. Mahoney
1-20 A CYBDOM protein impacts iron homeostasis and primary root growth under phosphate deficiency in Arabidopsis
by Joaquín Clúa & Jonatan Montpetit & Pedro Jimenez-Sandoval & Christin Naumann & Julia Santiago & Yves Poirier
1-20 Comprehensive detection and characterization of human druggable pockets through binding site descriptors
by Arnau Comajuncosa-Creus & Guillem Jorba & Xavier Barril & Patrick Aloy
1-20 Drosophila Evi5 is a critical regulator of intracellular iron transport via transferrin and ferritin interactions
by Sattar Soltani & Samuel M. Webb & Thomas Kroll & Kirst King-Jones
1-20 Trans-lesion synthesis and mismatch repair pathway crosstalk defines chemoresistance and hypermutation mechanisms in glioblastoma
by Xing Cheng & Jing An & Jitong Lou & Qisheng Gu & Weimin Ding & Gaith Nabil Droby & Yilin Wang & Chenghao Wang & Yanzhe Gao & Jay Ramanlal Anand & Abigail Shelton & Andrew Benson Satterlee & Breanna Mann & Yun-Chung Hsiao & Chih-Wei Liu & Kun Lu & Shawn Hingtgen & Jiguang Wang & Zhaoliang Liu & C. Ryan Miller & Di Wu & Cyrus Vaziri & Yang Yang
1-20 Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy
by Ella N. Hoogenboezem & Shrusti S. Patel & Justin H. Lo & Ashley B. Cavnar & Lauren M. Babb & Nora Francini & Eva F. Gbur & Prarthana Patil & Juan M. Colazo & Danielle L. Michell & Violeta M. Sanchez & Joshua T. McCune & Jinqi Ma & Carlisle R. DeJulius & Linus H. Lee & Jonah C. Rosch & Ryan M. Allen & Larry D. Stokes & Jordan L. Hill & Kasey C. Vickers & Rebecca S. Cook & Craig L. Duvall
1-20 The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development
by Pablo Gómez-del Arco & Joan Isern & Daniel Jimenez-Carretero & Dolores López-Maderuelo & Rebeca Piñeiro-Sabarís & Fadoua El Abdellaoui-Soussi & Carlos Torroja & María Linarejos Vera-Pedrosa & Mercedes Grima-Terrén & Alberto Benguria & Ana Simón-Chica & Antonio Queiro-Palou & Ana Dopazo & Fátima Sánchez-Cabo & José Jalife & José Luis Pompa & David Filgueiras-Rama & Pura Muñoz-Cánoves & Juan Miguel Redondo
1-20 Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
by Hongryeol Park & Jian Song & Hyun-Woo Jeong & Max L. B. Grönloh & Bong Ihn Koh & Esther Bovay & Kee-Pyo Kim & Luisa Klotz & Patricia A. Thistlethwaite & Jaap D. Buul & Lydia Sorokin & Ralf H. Adams
1-20 Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer
by Pengfei Xu & Joy C. Yang & Bo Chen & Shu Ning & Xiong Zhang & Leyi Wang & Christopher Nip & Yuqiu Shen & Oleta T. Johnson & Gabriela Grigorean & Brett Phinney & Liangren Liu & Qiang Wei & Eva Corey & Clifford G. Tepper & Hong-Wu Chen & Christopher P. Evans & Marc A. Dall’Era & Allen C. Gao & Jason E. Gestwicki & Chengfei Liu
1-20 Immunotherapy that improves response to chemotherapy in high-grade serous ovarian cancer
by Samar Elorbany & Chiara Berlato & Larissa S. Carnevalli & Eleni Maniati & Simon T. Barry & Jun Wang & Ranjit Manchanda & Julia Kzhyshkowska & Frances Balkwill
1-20 Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy
by Miguel A. Sánchez-Garrido & Víctor Serrano-López & Francisco Ruiz-Pino & María Jesús Vázquez & Andrea Rodríguez-Martín & Encarnación Torres & Inmaculada Velasco & Ana Belén Rodríguez & Eduardo Chicano-Gálvez & Marina Mora-Ortiz & Claes Ohlsson & Matti Poutanen & Leonor Pinilla & Francisco Gaytán & Jonathan D. Douros & Bin Yang & Timo D. Müller & Richard D. DiMarchi & Matthias H. Tschöp & Brian Finan & Manuel Tena-Sempere
1-20 Reliability of high-quantity human brain organoids for modeling microcephaly, glioma invasion and drug screening
by Anand Ramani & Giovanni Pasquini & Niklas J. Gerkau & Vaibhav Jadhav & Omkar Suhas Vinchure & Nazlican Altinisik & Hannes Windoffer & Sarah Muller & Ina Rothenaigner & Sean Lin & Aruljothi Mariappan & Dhanasekaran Rathinam & Ali Mirsaidi & Olivier Goureau & Lucia Ricci-Vitiani & Quintino Giorgio D’Alessandris & Bernd Wollnik & Alysson Muotri & Limor Freifeld & Nathalie Jurisch-Yaksi & Roberto Pallini & Christine R. Rose & Volker Busskamp & Elke Gabriel & Kamyar Hadian & Jay Gopalakrishnan
1-20 In situ editing of tumour cell membranes induces aggregation and capture of PD-L1 membrane proteins for enhanced cancer immunotherapy
by Chunping Mao & Fuan Deng & Wanning Zhu & Leiming Xie & Yijun Wang & Guoyin Li & Xingke Huang & Jiahui Wang & Yue Song & Ping Zeng & Zhenpeng He & Jingnan Guo & Yao Suo & Yujing Liu & Zhuo Chen & Mingxi Yao & Lu Zhang & Jun Shen
1-20 E-cardiac patch to sense and repair infarcted myocardium
by Renjie Qiu & Xingying Zhang & Chen Song & Kaige Xu & Huijia Nong & Yi Li & Xianglong Xing & Kibret Mequanint & Qian Liu & Quan Yuan & Xiaomin Sun & Malcolm Xing & Leyu Wang
1-20 A fast ceramic mixed OH−/H+ ionic conductor for low temperature fuel cells
by Peimiao Zou & Dinu Iuga & Sanliang Ling & Alex J. Brown & Shigang Chen & Mengfei Zhang & Yisong Han & A. Dominic Fortes & Christopher M. Howard & Shanwen Tao
1-20 The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression
by Meng Xu & Taku Ito-Kureha & Hyun-Seo Kang & Aleksandar Chernev & Timsse Raj & Kai P. Hoefig & Christine Hohn & Florian Giesert & Yinhu Wang & Wenliang Pan & Natalia Ziętara & Tobias Straub & Regina Feederle & Carolin Daniel & Barbara Adler & Julian König & Stefan Feske & George C. Tsokos & Wolfgang Wurst & Henning Urlaub & Michael Sattler & Jan Kisielow & F. Gregory Wulczyn & Marcin Łyszkiewicz & Vigo Heissmeyer
1-20 RNA nanotherapeutics with fibrosis overexpression and retention for MASH treatment
by Xinzhu Shan & Zhiqiang Zhao & Pingping Lai & Yuxiu Liu & Buyao Li & Yubin Ke & Hanqiu Jiang & Yilong Zhou & Wenzhe Li & Qian Wang & Pengxia Qin & Yizhe Xue & Zihan Zhang & Chenlong Wei & Bin Ma & Wei Liu & Cong Luo & Xueguang Lu & Jiaqi Lin & Li Shu & Yin Jie & Xunde Xian & Derfogail Delcassian & Yifan Ge & Lei Miao
1-20 Genetic influences on circulating retinol and its relationship to human health
by William R. Reay & Dylan J. Kiltschewskij & Maria A. Biase & Zachary F. Gerring & Kousik Kundu & Praveen Surendran & Laura A. Greco & Erin D. Clarke & Clare E. Collins & Alison M. Mondul & Demetrius Albanes & Murray J. Cairns
1-20 Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension
by Manasi Iyer & Husniye Kantarci & Madeline H. Cooper & Nicholas Ambiel & Sammy Weiser Novak & Leonardo R. Andrade & Mable Lam & Graham Jones & Alexandra E. Münch & Xinzhu Yu & Baljit S. Khakh & Uri Manor & J. Bradley Zuchero
1-20 The genetic architecture of protein interaction affinity and specificity
by Alexandra M. Bendel & Andre J. Faure & Dominique Klein & Kenji Shimada & Romane Lyautey & Nicole Schiffelholz & Georg Kempf & Simone Cavadini & Ben Lehner & Guillaume Diss
1-20 DCAF15 control of cohesin dynamics sustains acute myeloid leukemia
by Grant P. Grothusen & Renxu Chang & Zhendong Cao & Nan Zhou & Monika Mittal & Arindam Datta & Phillip Wulfridge & Thomas Beer & Baiyun Wang & Ning Zheng & Hsin-Yao Tang & Kavitha Sarma & Roger A. Greenberg & Junwei Shi & Luca Busino
1-20 Dopamine release plateau and outcome signals in dorsal striatum contrast with classic reinforcement learning formulations
by Min Jung Kim & Daniel J. Gibson & Dan Hu & Tomoko Yoshida & Emily Hueske & Ayano Matsushima & Ara Mahar & Cynthia J. Schofield & Patlapa Sompolpong & Kathy T. Tran & Lin Tian & Ann M. Graybiel
1-20 Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation
by Andrea Accogli & Saurabh Shakya & Taewoo Yang & Christine Insinna & Soo Yeon Kim & David Bell & Kirill R. Butov & Mariasavina Severino & Marcello Niceta & Marcello Scala & Hyun Sik Lee & Taekyeong Yoo & Jimmy Stauffer & Huijie Zhao & Chiara Fiorillo & Marina Pedemonte & Maria C. Diana & Simona Baldassari & Viktoria Zakharova & Anna Shcherbina & Yulia Rodina & Christina Fagerberg & Laura Sønderberg Roos & Jolanta Wierzba & Artur Dobosz & Amanda Gerard & Lorraine Potocki & Jill A. Rosenfeld & Seema R. Lalani & Tiana M. Scott & Daryl Scott & Mahshid S. Azamian & Raymond Louie & Hannah W. Moore & Neena L. Champaigne & Grace Hollingsworth & Annalaura Torella & Vincenzo Nigro & Rafal Ploski & Vincenzo Salpietro & Federico Zara & Simone Pizzi & Giovanni Chillemi & Marzia Ognibene & Erin Cooney & Jenny Do & Anders Linnemann & Martin J. Larsen & Suzanne Specht & Kylie J. Walters & Hee-Jung Choi & Murim Choi & Marco Tartaglia & Phillippe Youkharibache & Jong-Hee Chae & Valeria Capra & Sung-Gyoo Park & Christopher J. Westlake
1-20 Epigenomic and 3D genomic mapping reveals developmental dynamics and subgenomic asymmetry of transcriptional regulatory architecture in allotetraploid cotton
by Xianhui Huang & Yuejin Wang & Sainan Zhang & Liuling Pei & Jiaqi You & Yuexuan Long & Jianying Li & Xianlong Zhang & Longfu Zhu & Maojun Wang
1-20 The highly rugged yet navigable regulatory landscape of the bacterial transcription factor TetR
by Cauã Antunes Westmann & Leander Goldbach & Andreas Wagner
1-20 Human connectome topology directs cortical traveling waves and shapes frequency gradients
by Dominik P. Koller & Michael Schirner & Petra Ritter
1-20 Distinct medial amygdala oxytocin receptor neurons projections respectively control consolation or aggression in male mandarin voles
by Yishan Qu & Lizi Zhang & Wenjuan Hou & Limin Liu & Jing Liu & Lu Li & Xing Guo & Yin Li & Caihong Huang & Zhixiong He & Fadao Tai
1-20 Detection of senescence using machine learning algorithms based on nuclear features
by Imanol Duran & Joaquim Pombo & Bin Sun & Suchira Gallage & Hiromi Kudo & Domhnall McHugh & Laura Bousset & Jose Efren Barragan Avila & Roberta Forlano & Pinelopi Manousou & Mathias Heikenwalder & Dominic J. Withers & Santiago Vernia & Robert D. Goldin & Jesús Gil
1-20 Cell-type-specific mRNA transcription and degradation kinetics in zebrafish embryogenesis from metabolically labeled single-cell RNA-seq
by Lior Fishman & Avani Modak & Gal Nechooshtan & Talya Razin & Florian Erhard & Aviv Regev & Jeffrey A. Farrell & Michal Rabani
1-20 Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release
by Xuehan Zhou & Carrie Stine & Patricia Oliveira Prada & Debora Fusca & Kevin Assoumou & Jan Dernic & Musadiq A. Bhat & Ananya S. Achanta & Joseph C. Johnson & Amanda Loren Pasqualini & Sanjana Jadhav & Corinna A. Bauder & Lukas Steuernagel & Luca Ravotto & Dietmar Benke & Bruno Weber & Azra Suko & Richard D. Palmiter & Miriam Stoeber & Peter Kloppenburg & Jens C. Brüning & Michael R. Bruchas & Tommaso Patriarchi
1-20 An axonemal intron splicing program sustains Plasmodium male development
by Jiepeng Guan & Peijia Wu & Xiaoli Mo & Xiaolong Zhang & Wenqi Liang & Xiaoming Zhang & Lubin Jiang & Jian Li & Huiting Cui & Jing Yuan
1-20 An engineered AAV targeting integrin alpha V beta 6 presents improved myotropism across species
by Ai Vu Hong & Laurence Suel & Eva Petat & Auriane Dubois & Pierre-Romain Le Brun & Nicolas Guerchet & Philippe Veron & Jérôme Poupiot & Isabelle Richard
1-20 Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage
by Johanna Zerbib & Marica Rosaria Ippolito & Yonatan Eliezer & Giuseppina Feudis & Eli Reuveni & Anouk Savir Kadmon & Sara Martin & Sonia Viganò & Gil Leor & James Berstler & Julia Muenzner & Michael Mülleder & Emma M. Campagnolo & Eldad D. Shulman & Tiangen Chang & Carmela Rubolino & Kathrin Laue & Yael Cohen-Sharir & Simone Scorzoni & Silvia Taglietti & Alice Ratti & Chani Stossel & Talia Golan & Francesco Nicassio & Eytan Ruppin & Markus Ralser & Francisca Vazquez & Uri Ben-David & Stefano Santaguida
1-20 Flexible gating between subspaces in a neural network model of internally guided task switching
by Yue Liu & Xiao-Jing Wang
1-20 Inhibition of topoisomerase 2 catalytic activity impacts the integrity of heterochromatin and repetitive DNA and leads to interlinks between clustered repeats
by Michalis Amoiridis & John Verigos & Karen Meaburn & William H. Gittens & Tao Ye & Matthew J. Neale & Evi Soutoglou
1-20 Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency
by Rachel Tesla & Charlotte Guhl & Gordon C. Werthmann & Danielle Dixon & Basar Cenik & Yesu Addepalli & Jue Liang & Daniel M. Fass & Zachary Rosenthal & Stephen J. Haggarty & Noelle S. Williams & Bruce A. Posner & Joseph M. Ready & Joachim Herz
1-20 Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation
by Dominik Kiemel & Ann-Sophie Helene Kroell & Solène Denolly & Uta Haselmann & Jean-François Bonfanti & Jose Ignacio Andres & Brahma Ghosh & Peggy Geluykens & Suzanne J. F. Kaptein & Lucas Wilken & Pietro Scaturro & Johan Neyts & Marnix Loock & Olivia Goethals & Ralf Bartenschlager
1-20 VolcanoSV enables accurate and robust structural variant calling in diploid genomes from single-molecule long read sequencing
by Can Luo & Yichen Henry Liu & Xin Maizie Zhou
1-20 Identification and characterisation of pathogenic and non-pathogenic FGF14 repeat expansions
by Lars Mohren & Friedrich Erdlenbruch & Elsa Leitão & Fabian Kilpert & G. Sebastian Hönes & Sabine Kaya & Christopher Schröder & Andreas Thieme & Marc Sturm & Joohyun Park & Agatha Schlüter & Montserrat Ruiz & Moisés Morales de la Prida & Carlos Casasnovas & Kerstin Becker & Ulla Roggenbuck & Sonali Pechlivanis & Frank J. Kaiser & Matthis Synofzik & Thomas Wirth & Mathieu Anheim & Tobias B. Haack & Paul J. Lockhart & Karl-Heinz Jöckel & Aurora Pujol & Stephan Klebe & Dagmar Timmann & Christel Depienne
1-20 Liver cancer multiomics reveals diverse protein kinase A disruptions convergently produce fibrolamellar hepatocellular carcinoma
by David Requena & Jack A. Medico & Luis F. Soto-Ugaldi & Mahsa Shirani & James A. Saltsman & Michael S. Torbenson & Philip Coffino & Sanford M. Simon
1-20 AI-powered omics-based drug pair discovery for pyroptosis therapy targeting triple-negative breast cancer
by Boshu Ouyang & Caihua Shan & Shun Shen & Xinnan Dai & Qingwang Chen & Xiaomin Su & Yongbin Cao & Xifeng Qin & Ying He & Siyu Wang & Ruizhe Xu & Ruining Hu & Leming Shi & Tun Lu & Wuli Yang & Shaojun Peng & Jun Zhang & Jianxin Wang & Dongsheng Li & Zhiqing Pang
1-20 The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis
by Bing Yang & Liqing Lu & Ting Xiong & Wei Fan & Jiaohong Wang & Lucía Barbier-Torres & Jyoti Chhimwal & Sonal Sinha & Takashi Tsuchiya & Nirmala Mavila & Maria Lauda Tomasi & DuoYao Cao & Jing Zhang & Hui Peng & José M. Mato & Ting Liu & Xi Yang & Vladimir V. Kalinichenko & Komal Ramani & Jenny Han & Ekihiro Seki & Heping Yang & Shelly C. Lu
1-20 Intracellular magnesium optimizes transmission efficiency and plasticity of hippocampal synapses by reconfiguring their connectivity
by Hang Zhou & Guo-Qiang Bi & Guosong Liu
1-20 A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T Cell proliferation and anti-tumor immunity in mice
by Aman Mebrahtu & Ida Laurén & Rosanne Veerman & Gözde Güclüler Akpinar & Martin Lord & Alexandros Kostakis & Juan Astorga-Wells & Leif Dahllund & Anders Olsson & Oscar Andersson & Jonathan Persson & Helena Persson & Pierre Dönnes & Johan Rockberg & Sara Mangsbo
1-20 Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice
by Rúbens Prince dos Santos Alves & Julia Timis & Robyn Miller & Kristen Valentine & Paolla Beatriz Almeida Pinto & Andrew Gonzalez & Jose Angel Regla-Nava & Erin Maule & Michael N. Nguyen & Norazizah Shafee & Sara Landeras-Bueno & Eduardo Olmedillas & Brett Laffey & Katarzyna Dobaczewska & Zbigniew Mikulski & Sara McArdle & Sarah R. Leist & Kenneth Kim & Ralph S. Baric & Erica Ollmann Saphire & Annie Elong Ngono & Sujan Shresta
1-20 Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification
by Yong-Wei Xiong & Hua-Long Zhu & Jin Zhang & Hao Geng & Lu-Lu Tan & Xin-Mei Zheng & Hao Li & Long-Long Fan & Xin-Run Wang & Xu-Dong Zhang & Kai-Wen Wang & Wei Chang & Yu-Feng Zhang & Zhi Yuan & Zong-Liu Duan & Yun-Xia Cao & Xiao-Jin He & De-Xiang Xu & Hua Wang
1-20 A chloroplast localized heavy metal-associated domain containing protein regulates grain calcium accumulation in rice
by Huan Liu & Cun Lu & Xiang-Qian Liu & Chen-Jin Zhuo & Rong-Jian Luo & Qiu-Tang Huang & Zhong Tang & Chun-Qing Zhao & Mary Lou Guerinot & David E. Salt & Fang-Jie Zhao & Xin-Yuan Huang
1-20 Maintenance and transformation of representational formats during working memory prioritization
by Daniel Pacheco-Estefan & Marie-Christin Fellner & Lukas Kunz & Hui Zhang & Peter Reinacher & Charlotte Roy & Armin Brandt & Andreas Schulze-Bonhage & Linglin Yang & Shuang Wang & Jing Liu & Gui Xue & Nikolai Axmacher
1-20 Iron-depleting nutritional immunity controls extracellular bacterial replication in Legionella pneumophila infections
by Ascención Torres-Escobar & Ashley Wilkins & María D. Juárez-Rodríguez & Magdalena Circu & Brian Latimer & Ana-Maria Dragoi & Stanimir S. Ivanov
1-20 FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs
by Jason S. Wasserman & Bulat Faezov & Kishan R. Patel & Alison M. Kurimchak & Seren M. Palacio & David J. Glass & Holly Fowle & Brennan C. McEwan & Qifang Xu & Ziran Zhao & Lauren Cressey & Neil Johnson & James S. Duncan & Arminja N. Kettenbach & Roland L. Dunbrack & Xavier Graña
1-20 Engineered NLS-chimera downregulates expression of aggregation-prone endogenous FUS
by Miyuki Hayashi & Amandeep Girdhar & Ying-Hui Ko & Kevin M. Kim & Jacquelyn A. DePierro & Joseph R. Buchler & Nikhita Arunprakash & Aditya Bajaj & Gino Cingolani & Lin Guo
1-20 Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
by Giulia Schiroli & Vinay Kartha & Fabiana M. Duarte & Trine A. Kristiansen & Christina Mayerhofer & Rojesh Shrestha & Andrew Earl & Yan Hu & Tristan Tay & Catherine Rhee & Jason D. Buenrostro & David T. Scadden
1-20 Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis
by Naveen Kumar & Pon Ganish Prakash & Christian Wentland & Shilpa Mary Kurian & Gaurav Jethva & Volker Brinkmann & Hans-Joachim Mollenkopf & Tobias Krammer & Christophe Toussaint & Antoine-Emmanuel Saliba & Matthias Biebl & Christian Jürgensen & Bertram Wiedenmann & Thomas F. Meyer & Rajendra Kumar Gurumurthy & Cindrilla Chumduri
1-20 hnRNP R promotes O-GlcNAcylation of eIF4G and facilitates axonal protein synthesis
by Abdolhossein Zare & Saeede Salehi & Jakob Bader & Cornelius Schneider & Utz Fischer & Alexander Veh & Panagiota Arampatzi & Matthias Mann & Michael Briese & Michael Sendtner
1-20 SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration
by Jakob Hartmann & Thomas Bajaj & Joy Otten & Claudia Klengel & Tim Ebert & Anne-Kathrin Gellner & Ellen Junglas & Kathrin Hafner & Elmira A. Anderzhanova & Fiona Tang & Galen Missig & Lindsay Rexrode & Daniel T. Trussell & Katelyn X. Li & Max L. Pöhlmann & Sarah Mackert & Thomas M. Geiger & Daniel E. Heinz & Roy Lardenoije & Nina Dedic & Kenneth M. McCullough & Tomasz Próchnicki & Thomas Rhomberg & Silvia Martinelli & Antony Payton & Andrew C. Robinson & Valentin Stein & Eicke Latz & William A. Carlezon & Felix Hausch & Mathias V. Schmidt & Chris Murgatroyd & Sabina Berretta & Torsten Klengel & Harry Pantazopoulos & Kerry J. Ressler & Nils C. Gassen
1-20 VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction
by Harris E. Blankenship & Kelsey A. Carter & Kevin D. Pham & Nina T. Cassidy & Andrea N. Markiewicz & Michael I. Thellmann & Amanda L. Sharpe & Willard M. Freeman & Michael J. Beckstead
1-20 Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1
by Wenfeng Ren & Zilong Xu & Yating Chang & Fei Ju & Hongning Wu & Zhiqi Liang & Min Zhao & Naizhen Wang & Yanhua Lin & Chenhang Xu & Shengming Chen & Yipeng Rao & Chaolong Lin & Jianxin Yang & Pingguo Liu & Jun Zhang & Chenghao Huang & Ningshao Xia
1-20 Age-progressive interplay of HSP-proteostasis, ECM-cell junctions and biomechanics ensures C. elegans astroglial architecture
by Francesca Coraggio & Mahak Bhushan & Spyridon Roumeliotis & Francesca Caroti & Carlo Bevilacqua & Robert Prevedel & Georgia Rapti
1-20 Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
by David R. Ghasemi & Konstantin Okonechnikov & Anne Rademacher & Stephan Tirier & Kendra K. Maass & Hanna Schumacher & Piyush Joshi & Maxwell P. Gold & Julia Sundheimer & Britta Statz & Ahmet S. Rifaioglu & Katharina Bauer & Sabrina Schumacher & Michele Bortolomeazzi & Felice Giangaspero & Kati J. Ernst & Steven C. Clifford & Julio Saez-Rodriguez & David T. W. Jones & Daisuke Kawauchi & Ernest Fraenkel & Jan-Philipp Mallm & Karsten Rippe & Andrey Korshunov & Stefan M. Pfister & Kristian W. Pajtler
1-20 Regulating protein corona on nanovesicles by glycosylated polyhydroxy polymer modification for efficient drug delivery
by Yunqiu Miao & Lijun Li & Ying Wang & Jiangyue Wang & Yihan Zhou & Linmiao Guo & Yanqi Zhao & Di Nie & Yang Zhang & Xinxin Zhang & Yong Gan
1-20 SHANK3 depletion leads to ERK signalling overdose and cell death in KRAS-mutant cancers
by Johanna Lilja & Jasmin Kaivola & James R. W. Conway & Joni Vuorio & Hanna Parkkola & Pekka Roivas & Michal Dibus & Megan R. Chastney & Taru Varila & Guillaume Jacquemet & Emilia Peuhu & Emily Wang & Ulla Pentikäinen & Itziar Martinez D. Posada & Hellyeh Hamidi & Arafath K. Najumudeen & Owen J. Sansom & Igor L. Barsukov & Daniel Abankwa & Ilpo Vattulainen & Marko Salmi & Johanna Ivaska
1-20 Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice
by P. Bielefeld & A. Martirosyan & S. Martín-Suárez & A. Apresyan & G. F. Meerhoff & F. Pestana & S. Poovathingal & N. Reijner & W. Koning & R. A. Clement & I. Veen & E. M. Toledo & O. Polzer & I. Durá & S. Hovhannisyan & B. S. Nilges & A. Bogdoll & N. D. Kashikar & P. J. Lucassen & T. G. Belgard & J. M. Encinas & M. G. Holt & C. P. Fitzsimons
1-20 scConfluence: single-cell diagonal integration with regularized Inverse Optimal Transport on weakly connected features
by Jules Samaran & Gabriel Peyré & Laura Cantini
1-20 A presynaptic source drives differing levels of surround suppression in two mouse retinal ganglion cell types
by David Swygart & Wan-Qing Yu & Shunsuke Takeuchi & Rachel O. L. Wong & Gregory W. Schwartz
1-20 Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis
by Ahmed A. Raslan & Tho X. Pham & Jisu Lee & Konstantinos Kontodimas & Andrew Tilston-Lunel & Jillian Schmottlach & Jeongmin Hong & Taha Dinc & Andreea M. Bujor & Nunzia Caporarello & Aude Thiriot & Ulrich H. Andrian & Steven K. Huang & Roberto F. Nicosia & Maria Trojanowska & Xaralabos Varelas & Giovanni Ligresti
1-20 A family of NADPH/NADP+ biosensors reveals in vivo dynamics of central redox metabolism across eukaryotes
by Marie Scherschel & Jan-Ole Niemeier & Lianne J. H. C. Jacobs & Markus D. A. Hoffmann & Anika Diederich & Christopher Bell & Pascal Höhne & Sonja Raetz & Johanna B. Kroll & Janina Steinbeck & Sophie Lichtenauer & Jan Multhoff & Jannik Zimmermann & Tanmay Sadhanasatish & R. Alexander Rothemann & Carsten Grashoff & Joris Messens & Emmanuel Ampofo & Matthias W. Laschke & Jan Riemer & Leticia Prates Roma & Markus Schwarzländer & Bruce Morgan
1-20 Ngfr+ cholinergic projection from SI/nBM to mPFC selectively regulates temporal order recognition memory
by Fan Mei & Chen Zhao & Shangjin Li & Zeping Xue & Yueyang Zhao & Yihua Xu & Rongrong Ye & He You & Peng Yu & Xinyu Han & Gregory V. Carr & Daniel R. Weinberger & Feng Yang & Bai Lu
1-20 Elucidating human gut microbiota interactions that robustly inhibit diverse Clostridioides difficile strains across different nutrient landscapes
by Jordy Evan Sulaiman & Jaron Thompson & Yili Qian & Eugenio I. Vivas & Christian Diener & Sean M. Gibbons & Nasia Safdar & Ophelia S. Venturelli
1-20 Development of Aptamer-DNAzyme based metal-nucleic acid frameworks for gastric cancer therapy
by Jiaqi Yan & Rajendra Bhadane & Meixin Ran & Xiaodong Ma & Yuanqiang Li & Dongdong Zheng & Outi M. H. Salo-Ahen & Hongbo Zhang
1-20 FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer
by Zifeng Wang & Scott L. Townley & Songqi Zhang & Mingyu Liu & Muqing Li & Maryam Labaf & Susan Patalano & Kavita Venkataramani & Kellee R. Siegfried & Jill A. Macoska & Dong Han & Shuai Gao & Gail P. Risbridger & Renea A. Taylor & Mitchell G. Lawrence & Housheng Hansen He & Luke A. Selth & Changmeng Cai
1-20 TORC2 inhibition triggers yeast chromosome fragmentation through misregulated Base Excision Repair of clustered oxidation events
by Kenji Shimada & Cleo V. D. Tarashev & Stephanie Bregenhorn & Christian B. Gerhold & Barbara Loon & Gregory Roth & Verena Hurst & Josef Jiricny & Stephen B. Helliwell & Susan M. Gasser
1-20 GPATCH11 variants cause mis-splicing and early-onset retinal dystrophy with neurological impairment
by Andrea Zanetti & Gwendal Dujardin & Lucas Fares-Taie & Jeanne Amiel & Jérôme E. Roger & Isabelle Audo & Matthieu P. Robert & Pierre David & Vincent Jung & Nicolas Goudin & Ida Chiara Guerrera & Stéphanie Moriceau & Danielle Amana & Nurit Assia Batzir & Anat Bachar-Zipori & Lina Basel Salmon & Nathalie Boddaert & Sylvain Briault & Ange-Line Bruel & Christine Costet-Fighiera & Luisa Coutinho Santos & Cyril Gitiaux & Karolina Kaminska & Paul Kuentz & Naama Orenstein & Nicole Philip-Sarles & Morgane Plutino & Mathieu Quinodoz & Cristina Santos & Sabine Sigaudy & Mariana Soeiro e Sá & Efrat Sofrin & Ana Berta Sousa & Rui Sousa-Luis & Christel Thauvin-Robinet & Erwin L. van Dijk & Khaoula Zaafrane-Khachnaoui & Dinah Zur & Josseline Kaplan & Carlo Rivolta & Jean-Michel Rozet & Isabelle Perrault
1-20 Copy number losses of oncogenes and gains of tumor suppressor genes generate common driver mutations
by Elizaveta Besedina & Fran Supek
1-20 Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice
by Noushin Ahmadpour & Meher Kantroo & Michael J. Stobart & Jessica Meza-Resillas & Shahin Shabanipour & Jesus Parra-Nuñez & Tetiana Salamovska & Anna Muzaleva & Finnegan O’Hara & Dustin Erickson & Bruno Gaetano & Sofia Carrion-Falgarona & Bruno Weber & Alana Lamont & Natalie E. Lavine & Tiina M. Kauppinen & Michael F. Jackson & Jillian L. Stobart
1-20 Mst1-mediated phosphorylation of FoxO1 and C/EBP-β stimulates cell-protective mechanisms in cardiomyocytes
by Yasuhiro Maejima & Jihoon Nah & Zahra Aryan & Peiyong Zhai & Eun-Ah Sung & Tong Liu & Koichiro Takayama & Siavash Moghadami & Tetsuo Sasano & Hong Li & Junichi Sadoshima
1-20 Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits
by Hui Wu & Ling-Yun Luo & Ya-Hui Zhang & Chong-Yan Zhang & Jia-Hui Huang & Dong-Xin Mo & Li-Ming Zhao & Zhi-Xin Wang & Yi-Chuan Wang & EEr He-Hua & Wen-Lin Bai & Di Han & Xing-Tang Dou & Yan-Ling Ren & Renqing Dingkao & Hai-Liang Chen & Yong Ye & Hai-Dong Du & Zhan-Qiang Zhao & Xi-Jun Wang & Shan-Gang Jia & Zhi-Hong Liu & Meng-Hua Li
1-20 Chromosome architecture and low cohesion bias acrocentric chromosomes towards aneuploidy during mammalian meiosis
by Eirini Bellou & Agata P. Zielinska & Eike Urs Mönnich & Nina Schweizer & Antonio Z. Politi & Antonina Wellecke & Claus Sibold & Andreas Tandler-Schneider & Melina Schuh
1-20 Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver
by Abhishek Aich & Angela Boshnakovska & Steffen Witte & Tanja Gall & Kerstin Unthan-Fechner & Roya Yousefi & Arpita Chowdhury & Drishan Dahal & Aditi Methi & Svenja Kaufmann & Ivan Silbern & Jan Prochazka & Zuzana Nichtova & Marcela Palkova & Miles Raishbrook & Gizela Koubkova & Radislav Sedlacek & Simon E. Tröder & Branko Zevnik & Dietmar Riedel & Susann Michanski & Wiebke Möbius & Philipp Ströbel & Christian Lüchtenborg & Patrick Giavalisco & Henning Urlaub & Andre Fischer & Britta Brügger & Stefan Jakobs & Peter Rehling
1-20 Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer patient-derived xenografts
by Umberto Perron & Elena Grassi & Aikaterini Chatzipli & Marco Viviani & Emre Karakoc & Lucia Trastulla & Lorenzo M. Brochier & Claudio Isella & Eugenia R. Zanella & Hagen Klett & Ivan Molineris & Julia Schueler & Manel Esteller & Enzo Medico & Nathalie Conte & Ultan McDermott & Livio Trusolino & Andrea Bertotti & Francesco Iorio
1-20 Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters
by Ankita Leekha & Arash Saeedi & K M Samiur Rahman Sefat & Monish Kumar & Melisa Martinez-Paniagua & Adrian Damian & Rohan Kulkarni & Kate Reichel & Ali Rezvan & Shalaleh Masoumi & Xinli Liu & Laurence J. N. Cooper & Manu Sebastian & Courtney M. Sands & Vallabh E. Das & Nimesh B. Patel & Brett Hurst & Navin Varadarajan
1-20 53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR)
by Sameer Bikram Shah & Youhang Li & Shibo Li & Qing Hu & Tong Wu & Yanmeng Shi & Tran Nguyen & Isaac Ive & Linda Shi & Hailong Wang & Xiaohua Wu
1-20 Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor
by Ravi K. Lokareddy & Chun-Feng David Hou & Francesca Forti & Stephano M. Iglesias & Fenglin Li & Mikhail Pavlenok & David S. Horner & Michael Niederweis & Federica Briani & Gino Cingolani
1-20 Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy
by Agnes Forsthuber & Bertram Aschenbrenner & Ana Korosec & Tina Jacob & Karl Annusver & Natalia Krajic & Daria Kholodniuk & Sophie Frech & Shaohua Zhu & Kim Purkhauser & Katharina Lipp & Franziska Werner & Vy Nguyen & Johannes Griss & Wolfgang Bauer & Ana Soler Cardona & Benedikt Weber & Wolfgang Weninger & Bernhard Gesslbauer & Clement Staud & Jakob Nedomansky & Christine Radtke & Stephan N. Wagner & Peter Petzelbauer & Maria Kasper & Beate M. Lichtenberger
1-20 PTPN14 aggravates neointimal hyperplasia via boosting PDGFRβ signaling in smooth muscle cells
by Qiannan Ma & Xue He & Xue Wang & Guobing Zhao & Yanhong Zhang & Chao Su & Minxin Wei & Kai Zhang & Ming Liu & Yi Zhu & Jinlong He
1-20 β2 integrins impose a mechanical checkpoint on macrophage phagocytosis
by Alexander H. Settle & Benjamin Y. Winer & Miguel M. Jesus & Lauren Seeman & Zhaoquan Wang & Eric Chan & Yevgeniy Romin & Zhuoning Li & Matthew M. Miele & Ronald C. Hendrickson & Daan Vorselen & Justin S. A. Perry & Morgan Huse
1-20 IL-2 delivery to CD8+ T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics
by Diane Maurice & Patrick Costello & Jessica Diring & Francesco Gualdrini & Bruno Frederico & Richard Treisman
1-20 Glucocorticoids increase adiposity by stimulating Krüppel-like factor 9 expression in macrophages
by Yinliang Zhang & Chunyuan Du & Wei Wang & Wei Qiao & Yuhui Li & Yujie Zhang & Sufang Sheng & Xuenan Zhou & Lei Zhang & Heng Fan & Ying Yu & Yong Chen & Yunfei Liao & Shihong Chen & Yongsheng Chang
1-20 Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy
by Zaid Taha & Mathieu Joseph François Crupi & Nouf Alluqmani & Duncan MacKenzie & Sydney Vallati & Jack Timothy Whelan & Faiha Fareez & Akram Alwithenani & Julia Petryk & Andrew Chen & Marcus Mathew Spinelli & Kristy Ng & Judy Sobh & Christiano Tanese Souza & Priya Rose Bharadwa & Timothy Kit Hin Lee & Dylan Anthony Thomas & Ben Zhen Huang & Omar Kassas & Joanna Poutou & Victoria Heather Gilchrist & Stephen Boulton & Max Thomson & Ricardo Marius & Mohsen Hooshyar & Scott McComb & Rozanne Arulanandam & Carolina Solange Ilkow & John Cameron Bell & Jean-Simon Diallo
1-20 Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy
by Zhiqi Zhang & Xiaoxuan Xu & Jiawei Du & Xin Chen & Yonger Xue & Jianqiong Zhang & Xue Yang & Xiaoyuan Chen & Jinbing Xie & Shenghong Ju
1-20 Numb positively regulates Hedgehog signaling at the ciliary pocket
by Xiaoliang Liu & Patricia T. Yam & Sabrina Schlienger & Eva Cai & Jingyi Zhang & Wei-Ju Chen & Oscar Torres Gutierrez & Vanesa Jimenez Amilburu & Vasanth Ramamurthy & Alice Y. Ting & Tess C. Branon & Michel Cayouette & Risako Gen & Tessa Marks & Jennifer H. Kong & Frédéric Charron & Xuecai Ge
1-20 PDCD6 regulates lactate metabolism to modulate LC3-associated phagocytosis and antibacterial defense
by Lulu Sun & Sijin Wu & Hui Wang & Tianyu Zhang & Mengyu Zhang & Xuepeng Bai & Xiumei Zhang & Bingqing Li & Cai Zhang & Yan Li & Jun Zhou & Tianliang Li
1-20 Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa
by Sreelakshmi Vasudevan & Subhadip Senapati & Maryanne Pendergast & Paul S.–H. Park
1-20 Nuclear Hsp104 safeguards the dormant translation machinery during quiescence
by Verena Kohler & Andreas Kohler & Lisa Larsson Berglund & Xinxin Hao & Sarah Gersing & Axel Imhof & Thomas Nyström & Johanna L. Höög & Martin Ott & Claes Andréasson & Sabrina Büttner
1-20 Heterogeneity in strategy use during arbitration between experiential and observational learning
by Caroline J. Charpentier & Qianying Wu & Seokyoung Min & Weilun Ding & Jeffrey Cockburn & John P. O’Doherty
1-20 Genomic and panproteomic analysis of the development of infant immune responses to antigenically-diverse pneumococci
by Nicholas J. Croucher & Joseph J. Campo & Timothy Q. Le & Jozelyn V. Pablo & Christopher Hung & Andy A. Teng & Claudia Turner & François Nosten & Stephen D. Bentley & Xiaowu Liang & Paul Turner & David Goldblatt
1-20 Therapeutic efficacy of intracerebral hematopoietic stem cell gene therapy in an Alzheimer’s disease mouse model
by Rita Milazzo & Annita Montepeloso & Rajesh Kumar & Francesca Ferro & Eleonora Cavalca & Pietro Rigoni & Paolo Cabras & Yuri Ciervo & Sabyasachi Das & Alessia Capotondo & Danilo Pellin & Marco Peviani & Alessandra Biffi
1-20 Mitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity
by Lulu Ren & Jianqin Wan & Xiaoyan Li & Jie Yao & Yan Ma & Fanchao Meng & Shusen Zheng & Weidong Han & Hangxiang Wang
1-20 Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure
by Sudipta Das & Tomasz W. Kaminski & Brent T. Schlegel & William Bain & Sanmei Hu & Akruti Patel & Sagar L. Kale & Kong Chen & Janet S. Lee & Rama K. Mallampalli & Valerian E. Kagan & Dhivyaa Rajasundaram & Bryan J. McVerry & Prithu Sundd & Georgios D. Kitsios & Anuradha Ray & Prabir Ray
1-20 Aging drives cerebrovascular network remodeling and functional changes in the mouse brain
by Hannah C. Bennett & Qingguang Zhang & Yuan-ting Wu & Steffy B. Manjila & Uree Chon & Donghui Shin & Daniel J. Vanselow & Hyun-Jae Pi & Patrick J. Drew & Yongsoo Kim
1-20 CEP112 coordinates translational regulation of essential fertility genes during spermiogenesis through phase separation in humans and mice
by Xueguang Zhang & Gelin Huang & Ting Jiang & Lanlan Meng & Tongtong Li & Guohui Zhang & Nan Wu & Xinyi Chen & Bingwang Zhao & Nana Li & Sixian Wu & Junceng Guo & Rui Zheng & Zhiliang Ji & Zhigang Xu & Zhenbo Wang & Dong Deng & Yueqiu Tan & Wenming Xu
1-20 C-JUN overexpressing CAR-T cells in acute myeloid leukemia: preclinical characterization and phase I trial
by Shiyu Zuo & Chuo Li & Xiaolei Sun & Biping Deng & Yibing Zhang & Yajing Han & Zhuojun Ling & Jinlong Xu & Jiajia Duan & Zelin Wang & Xinjian Yu & Qinlong Zheng & Xiuwen Xu & Jiao Zong & Zhenglong Tian & Lingling Shan & Kaiting Tang & Huifang Huang & Yanzhi Song & Qing Niu & Dongming Zhou & Sizhou Feng & Zhongchao Han & Guoling Wang & Tong Wu & Jing Pan & Xiaoming Feng
1-20 Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota
by Vicki Mercado-Evans & Marlyd E. Mejia & Jacob J. Zulk & Samantha Ottinger & Zainab A. Hameed & Camille Serchejian & Madelynn G. Marunde & Clare M. Robertson & Mallory B. Ballard & Simone H. Ruano & Natalia Korotkova & Anthony R. Flores & Kathleen A. Pennington & Kathryn A. Patras
1-20 GLUT1 overexpression in CAR-T cells induces metabolic reprogramming and enhances potency
by Justin A. Guerrero & Dorota D. Klysz & Yiyun Chen & Meena Malipatlolla & Jameel Lone & Carley Fowler & Lucille Stuani & Audre May & Malek Bashti & Peng Xu & Jing Huang & Basil Michael & Kévin Contrepois & Shaurya Dhingra & Chris Fisher & Katrin J. Svensson & Kara L. Davis & Maya Kasowski & Steven A. Feldman & Elena Sotillo & Crystal L. Mackall
1-20 Evolution of T cells in the cancer-resistant naked mole-rat
by Tzuhua D. Lin & Nimrod D. Rubinstein & Nicole L. Fong & Megan Smith & Wendy Craft & Baby Martin-McNulty & Rebecca Perry & Martha A. Delaney & Margaret A. Roy & Rochelle Buffenstein
1-20 Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma
by Jourdin R. C. Rouaen & Antonietta Salerno & Tyler Shai-Hee & Jayne E. Murray & Giulia Castrogiovanni & Charlotte McHenry & Toni Rose Jue & Vu Pham & Jessica Lilian Bell & Ensieh Poursani & Emanuele Valli & Riccardo Cazzoli & Naomi Damstra & Delia J. Nelson & Kofi L. P. Stevens & Jonathan Chee & Iveta Slapetova & Maria Kasherman & Renee Whan & Francis Lin & Blake J. Cochran & Nicodemus Tedla & Feyza Colakoglu Veli & Aysen Yuksel & Chelsea Mayoh & Federica Saletta & Daniele Mercatelli & Tatyana Chtanova & Arutha Kulasinghe & Daniel Catchpoole & Giuseppe Cirillo & Maté Biro & Holger N. Lode & Fabio Luciani & Michelle Haber & Juliet C. Gray & Toby N. Trahair & Orazio Vittorio
1-20 The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells
by Xiaofeng Liao & Wenxue Li & Hongyue Zhou & Barani Kumar Rajendran & Ao Li & Jingjing Ren & Yi Luan & David A. Calderwood & Benjamin Turk & Wenwen Tang & Yansheng Liu & Dianqing Wu
1-20 LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model
by Alberto Díez-Sánchez & Håvard T. Lindholm & Pia M. Vornewald & Jenny Ostrop & Rouan Yao & Andrew B. Single & Anne Marstad & Naveen Parmar & Tovah N. Shaw & Mara Martín-Alonso & Menno J. Oudhoff
1-20 Parvalbumin-expressing basal forebrain neurons mediate learning from negative experience
by Panna Hegedüs & Bálint Király & Dániel Schlingloff & Victoria Lyakhova & Anna Velencei & Írisz Szabó & Márton I. Mayer & Zsofia Zelenak & Gábor Nyiri & Balázs Hangya
1-20 A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination
by Qing Bai & Enhua Shao & Denglei Ma & Binxuan Jiao & Seth D. Scheetz & Karen A. Hartnett-Scott & Vladimir A. Ilin & Elias Aizenman & Julia Kofler & Edward A. Burton
1-20 A hippocampus-accumbens code guides goal-directed appetitive behavior
by Oliver Barnstedt & Petra Mocellin & Stefan Remy
1-20 Primordial germ cell DNA demethylation and development require DNA translesion synthesis
by Pranay Shah & Ross Hill & Camille Dion & Stephen J. Clark & Abdulkadir Abakir & Jeroen Willems & Mark J. Arends & Juan I. Garaycoechea & Harry G. Leitch & Wolf Reik & Gerry P. Crossan
1-20 Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer
by Lisa Veghini & Davide Pasini & Rui Fang & Pietro Delfino & Dea Filippini & Christian Neander & Caterina Vicentini & Elena Fiorini & Francesca Lupo & Sabrina L. D’Agosto & Carmine Carbone & Antonio Agostini & Geny Piro & Diego Rosa & Michele Bevere & Peter Markus & Diana Behrens & Claudio Luchini & Rita T. Lawlor & Aldo Scarpa & Giulia Biffi & Phyllis F. Cheung & Jens T. Siveke & Vincenzo Corbo
1-20 A SPLICS reporter reveals $${{{{{\boldsymbol{\alpha }}}}}}$$ α -synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation
by Flavia Giamogante & Lucia Barazzuol & Francesca Maiorca & Elena Poggio & Alessandra Esposito & Anna Masato & Gennaro Napolitano & Alessio Vagnoni & Tito Calì & Marisa Brini
1-20 Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate
by Elena Ethel Vidal-Calvo & Anne Martin-Salazar & Swati Choudhary & Robert Dagil & Sai Sundar Rajan Raghavan & Lara Duvnjak & Mie Anemone Nordmaj & Thomas Mandel Clausen & Ann Skafte & Jan Oberkofler & Kaituo Wang & Mette Ø Agerbæk & Caroline Løppke & Amalie Mundt Jørgensen & Daria Ropac & Joana Mujollari & Shona Willis & Agnès Garcias López & Rebecca Louise Miller & Richard Torbjörn Gustav Karlsson & Felix Goerdeler & Yen-Hsi Chen & Ana R. Colaço & Yong Wang & Thomas Lavstsen & Agnieszka Martowicz & Irina Nelepcu & Mona Marzban & Htoo Zarni Oo & Maj Sofie Ørum-Madsen & Yuzhuo Wang & Morten A. Nielsen & Henrik Clausen & Michael Wierer & Dominik Wolf & Ismail Gögenur & Thor G. Theander & Nader Al-Nakouzi & Tobias Gustavsson & Mads Daugaard & Ali Salanti
1-20 Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32
by Samara Mishelle Ona Chuquimarca & Jonah Beenstock & Salima Daou & Jennifer Porat & Alexander F. A. Keszei & Jay Z. Yin & Tobias Beschauner & Mark A. Bayfield & Mohammad T. Mazhab-Jafari & Frank Sicheri
1-20 Basal actomyosin pulses expand epithelium coordinating cell flattening and tissue elongation
by Shun Li & Zong-Yuan Liu & Hao Li & Sijia Zhou & Jiaying Liu & Ningwei Sun & Kai-Fu Yang & Vanessa Dougados & Thomas Mangeat & Karine Belguise & Xi-Qiao Feng & Yiyao Liu & Xiaobo Wang
1-20 Temporal dendritic heterogeneity incorporated with spiking neural networks for learning multi-timescale dynamics
by Hanle Zheng & Zhong Zheng & Rui Hu & Bo Xiao & Yujie Wu & Fangwen Yu & Xue Liu & Guoqi Li & Lei Deng
1-20 High mobility group A1 (HMGA1) promotes the tumorigenesis of colorectal cancer by increasing lipid synthesis
by Yuan Zhao & Meng-Jie Liu & Lei Zhang & Qi Yang & Qian-Hui Sun & Jin-Rong Guo & Xin-Yuan Lei & Kai-Yue He & Jun-Qi Li & Jing-Yu Yang & Yong-Ping Jian & Zhi-Xiang Xu
1-20 Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence
by Athanasios Siametis & Kalliopi Stratigi & Despoina Giamaki & Georgia Chatzinikolaou & Alexia Akalestou-Clocher & Evi Goulielmaki & Brian Luke & Björn Schumacher & George A. Garinis
1-20 Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3
by Maja Zupančič & Erik Keimpema & Evgenii O. Tretiakov & Stephanie J. Eder & Itamar Lev & Lukas Englmaier & Pradeep Bhandari & Simone A. Fietz & Wolfgang Härtig & Estelle Renaux & Andreas Villunger & Tomas Hökfelt & Manuel Zimmer & Frédéric Clotman & Tibor Harkany
1-20 Facile engineering of interactive double network hydrogels for heart valve regeneration
by Jinsheng Li & Weihua Qiao & Yuqi Liu & Huiling Lei & Shuangshuang Wang & Yin Xu & Ying Zhou & Shuyu Wen & Zhuoran Yang & Wenyi Wan & Jiawei Shi & Nianguo Dong & Yuzhou Wu
1-20 The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment
by Elizabeth L. Hardaker & Emilio Sanseviero & Ankur Karmokar & Devon Taylor & Marta Milo & Chrysis Michaloglou & Adina Hughes & Mimi Mai & Matthew King & Anisha Solanki & Lukasz Magiera & Ricardo Miragaia & Gozde Kar & Nathan Standifer & Michael Surace & Shaan Gill & Alison Peter & Sara Talbot & Sehmus Tohumeken & Henderson Fryer & Ali Mostafa & Kathy Mulgrew & Carolyn Lam & Scott Hoffmann & Daniel Sutton & Larissa Carnevalli & Fernando J. Calero-Nieto & Gemma N. Jones & Andrew J. Pierce & Zena Wilson & David Campbell & Lynet Nyoni & Carla P. Martins & Tamara Baker & Gilberto Serrano de Almeida & Zainab Ramlaoui & Abdel Bidar & Benjamin Phillips & Joseph Boland & Sonia Iyer & J. Carl Barrett & Arsene-Bienvenu Loembé & Serge Y. Fuchs & Umamaheswar Duvvuri & Pei-Jen Lou & Melonie A. Nance & Carlos Alberto Gomez Roca & Elaine Cadogan & Susan E. Critichlow & Steven Fawell & Mark Cobbold & Emma Dean & Viia Valge-Archer & Alan Lau & Dmitry I. Gabrilovich & Simon T. Barry
1-20 Temporal asymmetries in inferring unobserved past and future events
by Xinming Xu & Ziyan Zhu & Xueyao Zheng & Jeremy R. Manning
1-20 The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function
by Yana Kibalnyk & Elia Afanasiev & Ronan M. N. Noble & Adrianne E. S. Watson & Irina Poverennaya & Nicole L. Dittmann & Maria Alexiou & Kara Goodkey & Amanda A. Greenwell & John R. Ussher & Igor Adameyko & James Massey & Daniel Graf & Stephane L. Bourque & Jo Anne Stratton & Anastassia Voronova
1-20 Glycolysis inhibition induces anti-tumor central memory CD8+T cell differentiation upon combination with microwave ablation therapy
by Xinyu Tang & Xinrui Mao & Peiwen Ling & Muxin Yu & Hua Pan & Jiaming Wang & Mingduo Liu & Hong Pan & Wen Qiu & Nan Che & Kai Zhang & Feifan Bao & Hongwei Peng & Qiang Ding & Shui Wang & Wenbin Zhou
1-20 Single-cell division tracing and transcriptomics reveal cell types and differentiation paths in the regenerating lung
by Leila R. Martins & Lina Sieverling & Michelle Michelhans & Chiara Schiller & Cihan Erkut & Thomas G. P. Grünewald & Sergio Triana & Stefan Fröhling & Lars Velten & Hanno Glimm & Claudia Scholl
1-20 An interaction network of inner centriole proteins organised by POC1A-POC1B heterodimer crosslinks ensures centriolar integrity
by Cornelia Sala & Martin Würtz & Enrico Salvatore Atorino & Annett Neuner & Patrick Partscht & Thomas Hoffmann & Sebastian Eustermann & Elmar Schiebel
1-20 Altered expression of Presenilin2 impacts endolysosomal homeostasis and synapse function in Alzheimer’s disease-relevant brain circuits
by Anika Perdok & Zoë P. Van Acker & Céline Vrancx & Ragna Sannerud & Inge Vorsters & Assunta Verrengia & Zsuzsanna Callaerts-Végh & Eline Creemers & Sara Gutiérrez Fernández & Britt D’hauw & Lutgarde Serneels & Keimpe Wierda & Lucía Chávez-Gutiérrez & Wim Annaert
1-20 DEAD-box ATPase Dbp2 is the key enzyme in an mRNP assembly checkpoint at the 3’-end of genes and involved in the recycling of cleavage factors
by Ebru Aydin & Silke Schreiner & Jacqueline Böhme & Birte Keil & Jan Weber & Bojan Žunar & Timo Glatter & Cornelia Kilchert
1-20 Arabidopsis CaLB1 undergoes phase separation with the ESCRT protein ALIX and modulates autophagosome maturation
by Niccolò Mosesso & Niharika Savant Lerner & Tobias Bläske & Felix Groh & Shane Maguire & Marie Laura Niedermeier & Eliane Landwehr & Karin Vogel & Konstanze Meergans & Marie-Kristin Nagel & Malte Drescher & Florian Stengel & Karin Hauser & Erika Isono
1-20 Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction
by Keith Siew & Kevin A. Nestler & Charlotte Nelson & Viola D’Ambrosio & Chutong Zhong & Zhongwang Li & Alessandra Grillo & Elizabeth R. Wan & Vaksha Patel & Eliah Overbey & JangKeun Kim & Sanghee Yun & Michael B. Vaughan & Chris Cheshire & Laura Cubitt & Jessica Broni-Tabi & Maneera Yousef Al-Jaber & Valery Boyko & Cem Meydan & Peter Barker & Shehbeel Arif & Fatemeh Afsari & Noah Allen & Mohammed Al-Maadheed & Selin Altinok & Nourdine Bah & Samuel Border & Amanda L. Brown & Keith Burling & Margareth Cheng-Campbell & Lorianna M. Colón & Lovorka Degoricija & Nichola Figg & Rebecca Finch & Jonathan Foox & Pouya Faridi & Alison French & Samrawit Gebre & Peter Gordon & Nadia Houerbi & Hossein Valipour Kahrood & Frederico C. Kiffer & Aleksandra S. Klosinska & Angela Kubik & Han-Chung Lee & Yinghui Li & Nicholas Lucarelli & Anthony L. Marullo & Irina Matei & Colleen M. McCann & Sayat Mimar & Ahmed Naglah & Jérôme Nicod & Kevin M. O’Shaughnessy & Lorraine Christine De Oliveira & Leah Oswalt & Laura Ioana Patras & San-huei Lai Polo & María Rodríguez-Lopez & Candice Roufosse & Omid Sadeghi-Alavijeh & Rebekah Sanchez-Hodge & Anindya S. Paul & Ralf Bernd Schittenhelm & Annalise Schweickart & Ryan T. Scott & Terry Chin Choy Lim Kam Sian & Willian A. Silveira & Hubert Slawinski & Daniel Snell & Julio Sosa & Amanda M. Saravia-Butler & Marshall Tabetah & Erwin Tanuwidjaya & Simon Walker-Samuel & Xiaoping Yang & Yasmin & Haijian Zhang & Jasminka Godovac-Zimmermann & Pinaki Sarder & Lauren M. Sanders & Sylvain V. Costes & Robert A. A. Campbell & Fathi Karouia & Vidya Mohamed-Alis & Samuel Rodriques & Steven Lynham & Joel Ricky Steele & Sergio Baranzini & Hossein Fazelinia & Zhongquan Dai & Akira Uruno & Dai Shiba & Masayuki Yamamoto & Eduardo A.C.Almeida & Elizabeth Blaber & Jonathan C. Schisler & Amelia J. Eisch & Masafumi Muratani & Sara R. Zwart & Scott M. Smith & Jonathan M. Galazka & Christopher E. Mason & Afshin Beheshti & Stephen B. Walsh
1-20 Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer’s disease
by Reji Babygirija & Michelle M. Sonsalla & Jericha Mill & Isabella James & Jessica H. Han & Cara L. Green & Mariah F. Calubag & Gina Wade & Anna Tobon & John Michael & Michaela M. Trautman & Ryan Matoska & Chung-Yang Yeh & Isaac Grunow & Heidi H. Pak & Michael J. Rigby & Dominique A. Baldwin & Natalie M. Niemi & John M. Denu & Luigi Puglielli & Judith Simcox & Dudley W. Lamming
1-20 YTHDF2 upregulation and subcellular localization dictate CD8 T cell polyfunctionality in anti-tumor immunity
by Haiyan Zhang & Xiaojing Luo & Wei Yang & Zhiying Wu & Zhicong Zhao & Xin Pei & Xue Zhang & Chonghao Chen & Josh Haipeng Lei & Qingxia Shi & Qi Zhao & Yanxing Chen & Wenwei Wu & Zhaolei Zeng & Huai-Qiang Ju & Miaozhen Qiu & Jun Liu & Bin Shen & Minshan Chen & Jianjun Chen & Chu-Xia Deng & Rui-Hua Xu & Jiajie Hou
1-20 FTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC
by Rong Li & Xijing Yan & Cuicui Xiao & Tingting Wang & Xuejiao Li & Zhongying Hu & Jinliang Liang & Jiebin Zhang & Jianye Cai & Xin Sui & Qiuli Liu & Manli Wu & Jiaqi Xiao & Haitian Chen & Yasong Liu & Chenhao Jiang & Guo Lv & Guihua Chen & Yingcai Zhang & Jia Yao & Jun Zheng & Yang Yang
1-20 Balancing competing effects of tissue growth and cytoskeletal regulation during Drosophila wing disc development
by Nilay Kumar & Jennifer Rangel Ambriz & Kevin Tsai & Mayesha Sahir Mim & Marycruz Flores-Flores & Weitao Chen & Jeremiah J. Zartman & Mark Alber
1-20 Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms
by Soeun Kang & Maciek R. Antoniewicz & Nissim Hay
1-20 Mycobacterial HelD connects RNA polymerase recycling with transcription initiation
by Tomáš Kovaľ & Nabajyoti Borah & Petra Sudzinová & Barbora Brezovská & Hana Šanderová & Viola Vaňková Hausnerová & Alena Křenková & Martin Hubálek & Mária Trundová & Kristýna Adámková & Jarmila Dušková & Marek Schwarz & Jana Wiedermannová & Jan Dohnálek & Libor Krásný & Tomáš Kouba
1-20 Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans
by Alina C. Teuscher & Cyril Statzer & Anita Goyala & Seraina A. Domenig & Ingmar Schoen & Max Hess & Alexander M. Hofer & Andrea Fossati & Viola Vogel & Orcun Goksel & Ruedi Aebersold & Collin Y. Ewald
1-20 Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma
by Daniel A. Ang & Jean-Michel Carter & Kamalakshi Deka & Joel H. L. Tan & Jianbiao Zhou & Qingfeng Chen & Wee Joo Chng & Nathan Harmston & Yinghui Li
1-20 Grid-like entorhinal representation of an abstract value space during prospective decision making
by Alexander Nitsch & Mona M. Garvert & Jacob L. S. Bellmund & Nicolas W. Schuck & Christian F. Doeller
1-20 BPG4 regulates chloroplast development and homeostasis by suppressing GLK transcription factors and involving light and brassinosteroid signaling
by Ryo Tachibana & Susumu Abe & Momo Marugami & Ayumi Yamagami & Rino Akema & Takao Ohashi & Kaisei Nishida & Shohei Nosaki & Takuya Miyakawa & Masaru Tanokura & Jong-Myong Kim & Motoaki Seki & Takehito Inaba & Minami Matsui & Kentaro Ifuku & Tetsuo Kushiro & Tadao Asami & Takeshi Nakano
1-20 Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease
by Ahmed Elwakiel & Dheerendra Gupta & Rajiv Rana & Jayakumar Manoharan & Moh’d Mohanad Al-Dabet & Saira Ambreen & Sameen Fatima & Silke Zimmermann & Akash Mathew & Zhiyang Li & Kunal Singh & Anubhuti Gupta & Surinder Pal & Alba Sulaj & Stefan Kopf & Constantin Schwab & Ronny Baber & Robert Geffers & Tom Götze & Bekas Alo & Christina Lamers & Paul Kluge & Georg Kuenze & Shrey Kohli & Thomas Renné & Khurrum Shahzad & Berend Isermann
1-20 Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment
by Kristian Juul-Madsen & Peter Parbo & Rola Ismail & Peter L. Ovesen & Vanessa Schmidt & Lasse S. Madsen & Jacob Thyrsted & Sarah Gierl & Mihaela Breum & Agnete Larsen & Morten N. Andersen & Marina Romero-Ramos & Christian K. Holm & Gregers R. Andersen & Huaying Zhao & Peter Schuck & Jens V. Nygaard & Duncan S. Sutherland & Simon F. Eskildsen & Thomas E. Willnow & David J. Brooks & Thomas Vorup-Jensen
1-20 Ultrasound-triggered and glycosylation inhibition-enhanced tumor piezocatalytic immunotherapy
by Yinying Pu & Bangguo Zhou & Jinhong Bing & Liang Wang & Mingqi Chen & Yucui Shen & Shuang Gao & Min Zhou & Wencheng Wu & Jianlin Shi
1-20 C5aR1 inhibition reprograms tumor associated macrophages and reverses PARP inhibitor resistance in breast cancer
by Xi Li & Alfonso Poire & Kang Jin Jeong & Dong Zhang & Tugba Yildiran Ozmen & Gang Chen & Chaoyang Sun & Gordon B. Mills
1-20 NME3 is a gatekeeper for DRP1-dependent mitophagy in hypoxia
by Chih-Wei Chen & Chi Su & Chang-Yu Huang & Xuan-Rong Huang & Xiaojing Cuili & Tung Chao & Chun-Hsiang Fan & Cheng-Wei Ting & Yi-Wei Tsai & Kai-Chien Yang & Ti-Yen Yeh & Sung-Tsang Hsieh & Yi-Ju Chen & Yuxi Feng & Tony Hunter & Zee-Fen Chang
1-20 BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections
by Shahul Hameed P & Harish Kotakonda & Sreevalli Sharma & Radha Nandishaiah & Nainesh Katagihallimath & Ranga Rao & Claire Sadler & Ian Slater & Michael Morton & Abhijeeth Chandrasekaran & Ed Griffen & Dhanashree Pillai & Sambasiva Reddy & Nagakumar Bharatham & Suryanarayanan Venkatesan & Venugopal Jonnalagadda & Ramesh Jayaraman & Mahesh Nanjundappa & Maitrayee Sharma & Savitha Raveendran & Sreenath Rajagopal & Harikrishna Tumma & Amy Watters & Holly Becker & Jill Lindley & Robert Flamm & Michael Huband & Dan Sahm & Meredith Hackel & Tarun Mathur & Ruwanthi Kolamunnage-Dona & Jennifer Unsworth & Laura Mcentee & Nikki Farrington & Dhanasekaran Manickam & Narayana Chandrashekara & Sivakandan Jayachandiran & Hrushikesava Reddy & Sathya Shanker & Vijay Richard & Teby Thomas & Savitha Nagaraj & Santanu Datta & Vasan Sambandamurthy & Vasanthi Ramachandran & Robert Clay & John Tomayko & Shampa Das & Balasubramanian V
1-20 Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing
by Lei Shen & Xiaokuang Ma & Yuanyuan Wang & Zhihao Wang & Yi Zhang & Hoang Quoc Hai Pham & Xiaoqun Tao & Yuehua Cui & Jing Wei & Dimitri Lin & Tharindumala Abeywanada & Swanand Hardikar & Levon Halabelian & Noah Smith & Taiping Chen & Dalia Barsyte-Lovejoy & Shenfeng Qiu & Yi Xing & Yanzhong Yang
1-20 Control of feeding by a bottom-up midbrain-subthalamic pathway
by Fernando M. C. V. Reis & Sandra Maesta-Pereira & Matthias Ollivier & Peter J. Schuette & Ekayana Sethi & Blake A. Miranda & Emily Iniguez & Meghmik Chakerian & Eric Vaughn & Megha Sehgal & Darren C. T. Nguyen & Faith T. H. Yuan & Anita Torossian & Juliane M. Ikebara & Alexandre H. Kihara & Alcino J. Silva & Jonathan C. Kao & Baljit S. Khakh & Avishek Adhikari
1-20 Genetic gains underpinning a little-known strawberry Green Revolution
by Mitchell J. Feldmann & Dominique D. A. Pincot & Glenn S. Cole & Steven J. Knapp
1-20 HURP binding to the vinca domain of β-tubulin accounts for cancer drug resistance
by Athira Saju & Po-Pang Chen & Tzu-Han Weng & Su-Yi Tsai & Akihiro Tanaka & Yu-Ting Tseng & Chih-Chia Chang & Chun-Hsiung Wang & Yuta Shimamoto & Kuo-Chiang Hsia
1-20 Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation
by Fei Sun & Nourhan Nashat Ali & Daniela Londoño-Vásquez & Constantine A. Simintiras & Huanyu Qiao & M. Sofia Ortega & Yuksel Agca & Masashi Takahashi & Rocío M. Rivera & Andrew M. Kelleher & Peter Sutovsky & Amanda L. Patterson & Ahmed Z. Balboula
1-20 Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability
by Petr Smirnov & Moritz J. Przybilla & Milena Simovic-Lorenz & R. Gonzalo Parra & Hana Susak & Manasi Ratnaparkhe & John KL. Wong & Verena Körber & Jan-Philipp Mallm & George Philippos & Martin Sill & Thorsten Kolb & Rithu Kumar & Nicola Casiraghi & Konstantin Okonechnikov & David R. Ghasemi & Kendra Korinna Maaß & Kristian W. Pajtler & Anna Jauch & Andrey Korshunov & Thomas Höfer & Marc Zapatka & Stefan M. Pfister & Wolfgang Huber & Oliver Stegle & Aurélie Ernst
1-20 Tomosyns attenuate SNARE assembly and synaptic depression by binding to VAMP2-containing template complexes
by Marieke Meijer & Miriam Öttl & Jie Yang & Aygul Subkhangulova & Avinash Kumar & Zicheng Feng & Torben W. Voorst & Alexander J. Groffen & Jan R. T. Weering & Yongli Zhang & Matthijs Verhage
1-20 Towards enhanced functionality of vagus neuroprostheses through in silico optimized stimulation
by Federico Ciotti & Robert John & Natalija Katic Secerovic & Noemi Gozzi & Andrea Cimolato & Naveen Jayaprakash & Weiguo Song & Viktor Toth & Theodoros Zanos & Stavros Zanos & Stanisa Raspopovic
1-20 Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies
by Rory Henderson & Kara Anasti & Kartik Manne & Victoria Stalls & Carrie Saunders & Yishak Bililign & Ashliegh Williams & Pimthada Bubphamala & Maya Montani & Sangita Kachhap & Jingjing Li & Chuancang Jaing & Amanda Newman & Derek W. Cain & Xiaozhi Lu & Sravani Venkatayogi & Madison Berry & Kshitij Wagh & Bette Korber & Kevin O. Saunders & Ming Tian & Fred Alt & Kevin Wiehe & Priyamvada Acharya & S. Munir Alam & Barton F. Haynes
1-20 Skin-inspired, sensory robots for electronic implants
by Lin Zhang & Sicheng Xing & Haifeng Yin & Hannah Weisbecker & Hiep Thanh Tran & Ziheng Guo & Tianhong Han & Yihang Wang & Yihan Liu & Yizhang Wu & Wanrong Xie & Chuqi Huang & Wei Luo & Michael Demaesschalck & Collin McKinney & Samuel Hankley & Amber Huang & Brynn Brusseau & Jett Messenger & Yici Zou & Wubin Bai
1-20 A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models
by Maritza Puray-Chavez & Jenna E. Eschbach & Ming Xia & Kyle M. LaPak & Qianzi Zhou & Ria Jasuja & Jiehong Pan & Jian Xu & Zixiang Zhou & Shawn Mohammed & Qibo Wang & Dana Q. Lawson & Sanja Djokic & Gaopeng Hou & Siyuan Ding & Steven L. Brody & Michael B. Major & Dennis Goldfarb & Sebla B. Kutluay
1-20 Programmed microalgae-gel promotes chronic wound healing in diabetes
by Yong Kang & Lingling Xu & Jinrui Dong & Xue Yuan & Jiamin Ye & Yueyue Fan & Bing Liu & Julin Xie & Xiaoyuan Ji
1-20 Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer
by Guoshu Bi & Jiaqi Liang & Yunyi Bian & Guangyao Shan & Yiwei Huang & Tao Lu & Huan Zhang & Xing Jin & Zhencong Chen & Mengnan Zhao & Hong Fan & Qun Wang & Boyi Gan & Cheng Zhan
1-20 Multi-modal deep learning enables efficient and accurate annotation of enzymatic active sites
by Xiaorui Wang & Xiaodan Yin & Dejun Jiang & Huifeng Zhao & Zhenxing Wu & Odin Zhang & Jike Wang & Yuquan Li & Yafeng Deng & Huanxiang Liu & Pei Luo & Yuqiang Han & Tingjun Hou & Xiaojun Yao & Chang-Yu Hsieh
1-20 A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV regulation
by M. Teresa Bertran & Robert Walmsley & Thomas Cummings & Iker Valle Aramburu & Donald J. Benton & Rocio Mora Molina & Jayalini Assalaarachchi & Maria Chasampalioti & Tessa Swanton & Dhira Joshi & Stefania Federico & Hanneke Okkenhaug & Lu Yu & David Oxley & Simon Walker & Venizelos Papayannopoulos & Hiroaki Suga & Maria A. Christophorou & Louise J. Walport
1-20 Immunosenescence and vaccine efficacy revealed by immunometabolic analysis of SARS-CoV-2-specific cells in multiple sclerosis patients
by Sara De Biasi & Domenico Lo Tartaro & Anita Neroni & Moritz Rau & Nikolaos Paschalidis & Rebecca Borella & Elena Santacroce & Annamaria Paolini & Lara Gibellini & Alin Liviu Ciobanu & Michela Cuccorese & Tommaso Trenti & Ignacio Rubio & Francesca Vitetta & Martina Cardi & Rafael José Argüello & Diana Ferraro & Andrea Cossarizza
1-20 TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice
by Michał Brouze & Agnieszka Czarnocka-Cieciura & Olga Gewartowska & Monika Kusio-Kobiałka & Kamil Jachacy & Marcin Szpila & Bartosz Tarkowski & Jakub Gruchota & Paweł Krawczyk & Seweryn Mroczek & Ewa Borsuk & Andrzej Dziembowski
1-20 Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity
by Ahmed E. I. Hamouda & Jessica Filtjens & Elisabeth Brabants & Daliya Kancheva & Ayla Debraekeleer & Jan Brughmans & Lotte Jacobs & Pauline M. R. Bardet & Elisabeth Knetemann & Pierre Lefesvre & Lize Allonsius & Mark Gontsarik & Ismael Varela & Marian Crabbé & Emile J. Clappaert & Federica Cappellesso & Aarushi A. Caro & Alícia Gordún Peiró & Luna Fredericq & Eva Hadadi & Mariona Estapé Senti & Raymond Schiffelers & Leo A. Grunsven & Frank Aboubakar Nana & Bruno G. Geest & Sofie Deschoemaeker & Stefaan Koker & Florence Lambolez & Damya Laoui
1-20 Membrane lipid nanodomains modulate HCN pacemaker channels in nociceptor DRG neurons
by Lucas J. Handlin & Natalie L. Macchi & Nicolas L. A. Dumaire & Lyuba Salih & Erin N. Lessie & Kyle S. McCommis & Aubin Moutal & Gucan Dai
1-20 INSIHGT: an accessible multi-scale, multi-modal 3D spatial biology platform
by Chun Ngo Yau & Jacky Tin Shing Hung & Robert A. A. Campbell & Thomas Chun Yip Wong & Bei Huang & Ben Tin Yan Wong & Nick King Ngai Chow & Lichun Zhang & Eldric Pui Lam Tsoi & Yuqi Tan & Joshua Jing Xi Li & Yun Kwok Wing & Hei Ming Lai
1-20 Massively parallel screen uncovers many rare 3′ UTR variants regulating mRNA abundance of cancer driver genes
by Ting Fu & Kofi Amoah & Tracey W. Chan & Jae Hoon Bahn & Jae-Hyung Lee & Sari Terrazas & Rockie Chong & Sriram Kosuri & Xinshu Xiao
1-20 PPIA dictates NRF2 stability to promote lung cancer progression
by Weiqiang Lu & Jiayan Cui & Wanyan Wang & Qian Hu & Yun Xue & Xi Liu & Ting Gong & Yiping Lu & Hui Ma & Xinyu Yang & Bo Feng & Qi Wang & Naixia Zhang & Yechun Xu & Mingyao Liu & Ruth Nussinov & Feixiong Cheng & Hongbin Ji & Jin Huang
1-20 Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization
by Tea Babushku & Markus Lechner & Stefanie Ehrenberg & Ursula Rambold & Marc Schmidt-Supprian & Andrew J. Yates & Sanket Rane & Ursula Zimber-Strobl & Lothar J. Strobl
1-20 Placebo treatment affects brain systems related to affective and cognitive processes, but not nociceptive pain
by Rotem Botvinik-Nezer & Bogdan Petre & Marta Ceko & Martin A. Lindquist & Naomi P. Friedman & Tor D. Wager
1-20 Focal adhesions contain three specialized actin nanoscale layers
by Reena Kumari & Katharina Ven & Megan Chastney & Shrikant B. Kokate & Johan Peränen & Jesse Aaron & Konstantin Kogan & Leonardo Almeida-Souza & Elena Kremneva & Renaud Poincloux & Teng-Leong Chew & Peter W. Gunning & Johanna Ivaska & Pekka Lappalainen
1-20 Defects in hair cells disrupt the development of auditory peripheral circuitry
by Riley T. Bottom & Yijun Xu & Caroline Siebald & Jinsei Jung & Ulrich Müller
1-20 Stress increases sperm respiration and motility in mice and men
by Nickole Moon & Christopher P. Morgan & Ruth Marx-Rattner & Alyssa Jeng & Rachel L. Johnson & Ijeoma Chikezie & Carmen Mannella & Mary D. Sammel & C. Neill Epperson & Tracy L. Bale
1-20 Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy
by Zhangyi Luo & Yixian Huang & Neelu Batra & Yuang Chen & Haozhe Huang & Yifei Wang & Ziqian Zhang & Shichen Li & Chien-Yu Chen & Zehua Wang & Jingjing Sun & Qiming Jane Wang & Da Yang & Binfeng Lu & James F. Conway & Lu-Yuan Li & Ai-Ming Yu & Song Li
1-20 Neutral ceramidase regulates breast cancer progression by metabolic programming of TREM2-associated macrophages
by Rui Sun & Chao Lei & Zhishan Xu & Xuemei Gu & Liu Huang & Liang Chen & Yi Tan & Min Peng & Kavitha Yaddanapudi & Leah Siskind & Maiying Kong & Robert Mitchell & Jun Yan & Zhongbin Deng
1-20 Correlative single molecule lattice light sheet imaging reveals the dynamic relationship between nucleosomes and the local chromatin environment
by Timothy A. Daugird & Yu Shi & Katie L. Holland & Hosein Rostamian & Zhe Liu & Luke D. Lavis & Joseph Rodriguez & Brian D. Strahl & Wesley R. Legant
1-20 Capture of RNA-binding proteins across mouse tissues using HARD-AP
by Yijia Ren & Hongyu Liao & Jun Yan & Hongyu Lu & Xiaowei Mao & Chuan Wang & Yi-fei Li & Yu Liu & Chong Chen & Lu Chen & Xiangfeng Wang & Kai-Yu Zhou & Han-Min Liu & Yi Liu & Yi-Min Hua & Lin Yu & Zhihong Xue
1-20 Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage
by Ke Gong & Chao Xue & Zian Feng & Ruru Pan & Mengyao Wang & Shasha Chen & Yuanli Chen & Yudong Guan & Lingyun Dai & Shuang Zhang & Liwei Jiang & Ling Li & Bei Wang & Zequn Yin & Likun Ma & Yasuko Iwakiri & Junming Tang & Chenzhong Liao & Houzao Chen & Yajun Duan
1-20 Androgen drives melanoma invasiveness and metastatic spread by inducing tumorigenic fucosylation
by Qian Liu & Emma Adhikari & Daniel K. Lester & Bin Fang & Joseph O. Johnson & Yijun Tian & Andrea T. Mockabee-Macias & Victoria Izumi & Kelly M. Guzman & Michael G. White & John M. Koomen & Jennifer A. Wargo & Jane L. Messina & Jianfei Qi & Eric K. Lau
1-20 Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade
by Christina A. Roemeling & Jeet A. Patel & Savannah L. Carpenter & Oleg Yegorov & Changlin Yang & Alisha Bhatia & Bently P. Doonan & Rylynn Russell & Vrunda S. Trivedi & Kelena Klippel & Daniel H. Ryu & Adam Grippin & Hunter S. Futch & Yong Ran & Lan B. Hoang-Minh & Frances L. Weidert & Todd E. Golde & Duane A. Mitchell
1-20 Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53
by Rafaela Muniz de Queiroz & Gizem Efe & Asja Guzman & Naoko Hashimoto & Yusuke Kawashima & Tomoaki Tanaka & Anil K. Rustgi & Carol Prives
1-20 The vacuolar fusion regulated by HOPS complex promotes hyphal initiation and penetration in Candida albicans
by Yu Liu & Ruina Wang & Jiacun Liu & Mengting Fan & Zi Ye & Yumeng Hao & Fei Xie & Ting Wang & Yuanying Jiang & Ningning Liu & Xiaoyan Cui & Quanzhen Lv & Lan Yan
1-20 SUMOylation of Warts kinase promotes neural stem cell reactivation
by Yang Gao & Ye Sing Tan & Jiaen Lin & Liang Yuh Chew & Htet Yamin Aung & Brinda Palliyana & Mahekta R. Gujar & Kun-Yang Lin & Shu Kondo & Hongyan Wang
1-20 The extensive m5C epitranscriptome of Thermococcus kodakarensis is generated by a suite of RNA methyltransferases that support thermophily
by Kristin A. Fluke & Ryan T. Fuchs & Yueh-Lin Tsai & Victoria Talbott & Liam Elkins & Hallie P. Febvre & Nan Dai & Eric J. Wolf & Brett W. Burkhart & Jackson Schiltz & G. Brett Robb & Ivan R. Corrêa & Thomas J. Santangelo
1-20 Prediction-error signals in anterior cingulate cortex drive task-switching
by Nicholas Cole & Matthew Harvey & Dylan Myers-Joseph & Aditya Gilra & Adil G. Khan
1-20 Developmental basis of SHH medulloblastoma heterogeneity
by Maxwell P. Gold & Winnie Ong & Andrew M. Masteller & David R. Ghasemi & Julie Anne Galindo & Noel R. Park & Nhan C. Huynh & Aneesh Donde & Veronika Pister & Raul A. Saurez & Maria C. Vladoiu & Grace H. Hwang & Tanja Eisemann & Laura K. Donovan & Adam D. Walker & Joseph Benetatos & Christelle Dufour & Livia Garzia & Rosalind A. Segal & Robert J. Wechsler-Reya & Jill P. Mesirov & Andrey Korshunov & Kristian W. Pajtler & Scott L. Pomeroy & Olivier Ayrault & Shawn M. Davidson & Jennifer A. Cotter & Michael D. Taylor & Ernest Fraenkel
1-20 Integrative 3D genomics with multi-omics analysis and functional validation of genetic regulatory mechanisms of abdominal fat deposition in chickens
by Linyong Shen & Xue Bai & Liru Zhao & Jiamei Zhou & Cheng Chang & Xinquan Li & Zhiping Cao & Yumao Li & Peng Luan & Hui Li & Hui Zhang
1-20 Deep cell phenotyping and spatial analysis of multiplexed imaging with TRACERx-PHLEX
by Alastair Magness & Emma Colliver & Katey S. S. Enfield & Claudia Lee & Masako Shimato & Emer Daly & David A. Moore & Monica Sivakumar & Karishma Valand & Dina Levi & Crispin T. Hiley & Philip S. Hobson & Febe Maldegem & James L. Reading & Sergio A. Quezada & Julian Downward & Erik Sahai & Charles Swanton & Mihaela Angelova
1-20 Organizing space through saccades and fixations between primate posterior parietal cortex and hippocampus
by Marie E. Vericel & Pierre Baraduc & Jean-René Duhamel & Sylvia Wirth
1-20 Synaptic connectome of the Drosophila circadian clock
by Nils Reinhard & Ayumi Fukuda & Giulia Manoli & Emilia Derksen & Aika Saito & Gabriel Möller & Manabu Sekiguchi & Dirk Rieger & Charlotte Helfrich-Förster & Taishi Yoshii & Meet Zandawala
1-20 Disordered regions of human eIF4B orchestrate a dynamic self-association landscape
by Bikash Chandra Swain & Pascale Sarkis & Vanessa Ung & Sabrina Rousseau & Laurent Fernandez & Ani Meltonyan & V. Esperance Aho & Davide Mercadante & Cameron D. Mackereth & Mikayel Aznauryan
1-20 Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes
by Carlos Company & Matthias Jürgen Schmitt & Yuliia Dramaretska & Michela Serresi & Sonia Kertalli & Ben Jiang & Jiang-An Yin & Adriano Aguzzi & Iros Barozzi & Gaetano Gargiulo
1-20 Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors
by Xiaowei Bian & Minna Piipponen & Zhuang Liu & Lihua Luo & Jennifer Geara & Yongjian Chen & Traimate Sangsuwan & Monica Maselli & Candice Diaz & Connor A. Bain & Evelien Eenjes & Maria Genander & Michael Crichton & Jenna L. Cash & Louis Archambault & Siamak Haghdoost & Julie Fradette & Pehr Sommar & Martin Halle & Ning Xu Landén
1-20 Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation
by David Rombaut & Carine Lefèvre & Tony Rached & Sabrina Bondu & Anne Letessier & Raphael M. Mangione & Batoul Farhat & Auriane Lesieur-Pasquier & Daisy Castillo-Guzman & Ismael Boussaid & Chloé Friedrich & Aurore Tourville & Magali De Carvalho & Françoise Levavasseur & Marjorie Leduc & Morgane Le Gall & Sarah Battault & Marie Temple & Alexandre Houy & Didier Bouscary & Lise Willems & Sophie Park & Sophie Raynaud & Thomas Cluzeau & Emmanuelle Clappier & Pierre Fenaux & Lionel Adès & Raphael Margueron & Michel Wassef & Samar Alsafadi & Nicolas Chapuis & Olivier Kosmider & Eric Solary & Angelos Constantinou & Marc-Henri Stern & Nathalie Droin & Benoit Palancade & Benoit Miotto & Frédéric Chédin & Michaela Fontenay
1-20 Targeting fatty acid oxidation enhances response to HER2-targeted therapy
by Ipshita Nandi & Linjia Ji & Harvey W. Smith & Daina Avizonis & Vasilios Papavasiliou & Cynthia Lavoie & Alain Pacis & Sherif Attalla & Virginie Sanguin-Gendreau & William J. Muller
1-20 A deterministic, c-di-GMP-dependent program ensures the generation of phenotypically similar, symmetric daughter cells during cytokinesis
by María Pérez-Burgos & Marco Herfurth & Andreas Kaczmarczyk & Andrea Harms & Katrin Huber & Urs Jenal & Timo Glatter & Lotte Søgaard-Andersen
1-20 TopBP1 utilises a bipartite GINS binding mode to support genome replication
by Matthew Day & Bilal Tetik & Milena Parlak & Yasser Almeida-Hernández & Markus Räschle & Farnusch Kaschani & Heike Siegert & Anika Marko & Elsa Sanchez-Garcia & Markus Kaiser & Isabel A. Barker & Laurence H. Pearl & Antony W. Oliver & Dominik Boos
1-20 Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum
by Ting-Feng Lin & Silas E. Busch & Christian Hansel
1-20 Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer
by Mindy K. Graham & Rulin Wang & Roshan Chikarmane & Bulouere Abel & Ajay Vaghasia & Anuj Gupta & Qizhi Zheng & Jessica Hicks & Polina Sysa-Shah & Xin Pan & Nicole Castagna & Jianyong Liu & Jennifer Meyers & Alyza Skaist & Yan Zhang & Michael Rubenstein & Kornel Schuebel & Brian W. Simons & Charles J. Bieberich & William G. Nelson & Shawn E. Lupold & Theodore L. DeWeese & Angelo M. De Marzo & Srinivasan Yegnasubramanian
1-20 HuR controls glutaminase RNA metabolism
by Douglas Adamoski & Larissa M. dos Reis & Ana Carolina Paschoalini Mafra & Felipe Corrêa-da-Silva & Pedro Manoel Mendes de Moraes-Vieira & Ioana Berindan-Neagoe & George A. Calin & Sandra Martha Gomes Dias
1-20 Distributed feature representations of natural stimuli across parallel retinal pathways
by Jen-Chun Hsiang & Ning Shen & Florentina Soto & Daniel Kerschensteiner
1-20 Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase
by Darja Andreev & Katerina Kachler & Mengdan Liu & Zhu Chen & Brenda Krishnacoumar & Mark Ringer & Silke Frey & Gerhard Krönke & David Voehringer & Georg Schett & Aline Bozec
1-20 KAP1 negatively regulates RNA polymerase II elongation kinetics to activate signal-induced transcription
by Usman Hyder & Ashwini Challa & Micah Thornton & Tulip Nandu & W. Lee Kraus & Iván D’Orso
1-20 Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression
by Fatima Khan & Yiyun Lin & Heba Ali & Lizhi Pang & Madeline Dunterman & Wen-Hao Hsu & Katie Frenis & R. Grant Rowe & Derek A. Wainwright & Kathleen McCortney & Leah K. Billingham & Jason Miska & Craig Horbinski & Maciej S. Lesniak & Peiwen Chen
1-20 Design of target specific peptide inhibitors using generative deep learning and molecular dynamics simulations
by Sijie Chen & Tong Lin & Ruchira Basu & Jeremy Ritchey & Shen Wang & Yichuan Luo & Xingcan Li & Dehua Pei & Levent Burak Kara & Xiaolin Cheng
1-20 Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity
by Takeshi Katsuda & Jonathan H. Sussman & Kenji Ito & Andrew Katznelson & Salina Yuan & Naomi Takenaka & Jinyang Li & Allyson J. Merrell & Hector Cure & Qinglan Li & Reyaz Ur Rasool & Irfan A. Asangani & Kenneth S. Zaret & Ben Z. Stanger
1-20 Genetic architecture of the structural connectome
by Michael Wainberg & Natalie J. Forde & Salim Mansour & Isabel Kerrebijn & Sarah E. Medland & Colin Hawco & Shreejoy J. Tripathy
1-20 A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain
by Sofia Madsen & Ana C. Delgado & Christelle Cadilhac & Vanille Maillard & Fabrice Battiston & Carla Marie Igelbüscher & Simon De Neck & Elia Magrinelli & Denis Jabaudon & Ludovic Telley & Fiona Doetsch & Marlen Knobloch
1-20 FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading
by Akbar Zainu & Pauline Dupaigne & Soumya Bouchouika & Julien Cau & Julie A. J. Clément & Pauline Auffret & Virginie Ropars & Jean-Baptiste Charbonnier & Bernard Massy & Raphael Mercier & Rajeev Kumar & Frédéric Baudat
1-20 Biallelic NAA60 variants with impaired N-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications
by Viorica Chelban & Henriette Aksnes & Reza Maroofian & Lauren C. LaMonica & Luis Seabra & Anette Siggervåg & Perrine Devic & Hanan E. Shamseldin & Jana Vandrovcova & David Murphy & Anne-Claire Richard & Olivier Quenez & Antoine Bonnevalle & M. Natalia Zanetti & Rauan Kaiyrzhanov & Vincenzo Salpietro & Stephanie Efthymiou & Lucia V. Schottlaender & Heba Morsy & Annarita Scardamaglia & Ambreen Tariq & Alistair T. Pagnamenta & Ajia Pennavaria & Liv S. Krogstad & Åse K. Bekkelund & Alessia Caiella & Nina Glomnes & Kirsten M. Brønstad & Sandrine Tury & Andrés Moreno De Luca & Anne Boland-Auge & Robert Olaso & Jean-François Deleuze & Mathieu Anheim & Benjamin Cretin & Barbara Vona & Fahad Alajlan & Firdous Abdulwahab & Jean-Luc Battini & Rojan İpek & Peter Bauer & Giovanni Zifarelli & Serdal Gungor & Semra Hiz Kurul & Hanns Lochmuller & Sahar I. Da’as & Khalid A. Fakhro & Alicia Gómez-Pascual & Juan A. Botía & Nicholas W. Wood & Rita Horvath & Andreas M. Ernst & James E. Rothman & Meriel McEntagart & Yanick J. Crow & Fowzan S. Alkuraya & Gaël Nicolas & Thomas Arnesen & Henry Houlden
1-20 Peptidylprolyl isomerase A guides SENP5/GAU1 DNA-lncRNA triplex generation for driving tumorigenesis
by Xiaoyu Zhang & Tianyi Ding & Fan Yang & Jixing Zhang & Haowen Xu & Yiran Bai & Yibing Shi & Jiaqi Yang & Chaoqun Chen & Chengbo Zhu & He Zhang
1-20 Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice
by Mei-Xin Li & Sheng Hu & He-Hua Lei & Meng Yuan & Xu Li & Wen-Kui Hou & Xiang-Jie Huang & Bing-Wen Xiao & Teng-Xiang Yu & Xiao-Hui Zhang & Xiao-Ting Wu & Wen-Qiang Jing & Hyeon-Jeong Lee & Juan-Juan Li & Da Fu & Li-Min Zhang & Wei Yan
1-20 Two-dimensional coordination risedronate-manganese nanobelts as adjuvant for cancer radiotherapy and immunotherapy
by Zhusheng Huang & Shiqian Huang & Simin Song & Yankui Ding & Hao Zhou & Shaoyin Zhang & Lixing Weng & Ying Zhang & Yiqiao Hu & Ahu Yuan & Yunlu Dai & Zhimin Luo & Lianhui Wang
1-20 The reactive pyruvate metabolite dimethylglyoxal mediates neurological consequences of diabetes
by Sina Rhein & Riccardo Costalunga & Julica Inderhees & Tammo Gürtzgen & Teresa Christina Faupel & Zaib Shaheryar & Adriana Arrulo Pereira & Alaa Othman & Kimberly Begemann & Sonja Binder & Ines Stölting & Valentina Dorta & Peter P. Nawroth & Thomas Fleming & Konrad Oexle & Vincent Prevot & Ruben Nogueiras & Svenja Meyhöfer & Sebastian M. Meyhöfer & Markus Schwaninger
1-20 Dissemination of pathogenic bacteria is reinforced by a MARTX toxin effector duet
by Sanghyeon Choi & Youngjin Lee & Shinhye Park & Song Yee Jang & Jongbin Park & Do Won Oh & Su-Man Kim & Tae-Hwan Kim & Ga Seul Lee & Changyi Cho & Byoung Sik Kim & Donghan Lee & Eun-Hee Kim & Hae-Kap Cheong & Jeong Hee Moon & Ji-Joon Song & Jungwon Hwang & Myung Hee Kim
1-20 RING1 missense variants reveal sensitivity of DNA damage repair to H2A monoubiquitination dosage during neurogenesis
by C. W. Ryan & S. L. Regan & E. F. Mills & B. T. McGrath & E. Gong & Y. T. Lai & J. B. Sheingold & K. Patel & T. Horowitz & A. Moccia & Y. C. Tsan & A. Srivastava & S. L. Bielas
1-20 The FvABF3-FvALKBH10B-FvSEP3 cascade regulates fruit ripening in strawberry
by Renkun Tang & Xiaoyu Duan & Leilei Zhou & Guangtong Gao & Jinying Liu & Yuying Wang & Xingfeng Shao & Guozheng Qin
1-20 Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology
by Thomas M. Goralski & Lindsay Meyerdirk & Libby Breton & Laura Brasseur & Kevin Kurgat & Daniella DeWeerd & Lisa Turner & Katelyn Becker & Marie Adams & Daniel J. Newhouse & Michael X. Henderson
1-20 ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation
by Luigi Mazzeo & Soumitra Ghosh & Emery Di Cicco & Jovan Isma & Daniele Tavernari & Anastasia Samarkina & Paola Ostano & Markus K. Youssef & Christian Simon & G. Paolo Dotto
1-20 ARID1A safeguards the canalization of the cell fate decision during osteoclastogenesis
by Jiahui Du & Yili Liu & Jinrui Sun & Enhui Yao & Jingyi Xu & Xiaolin Wu & Ling Xu & Mingliang Zhou & Guangzheng Yang & Xinquan Jiang
1-20 Tyrosol blocks E. coli anaerobic biofilm formation via YbfA and FNR to increase antibiotic susceptibility
by Ha-Young Choi & Won-Gon Kim
1-20 Enhancing aortic valve drug delivery with PAR2-targeting magnetic nano-cargoes for calcification alleviation
by Jinyong Chen & Tanchen Ren & Lan Xie & Haochang Hu & Xu Li & Miribani Maitusong & Xuhao Zhou & Wangxing Hu & Dilin Xu & Yi Qian & Si Cheng & Kaixiang Yu & Jian`an Wang & Xianbao Liu
1-20 Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
by Yang Zhao & Jingyuan Ning & Hongqi Teng & Yalan Deng & Marisela Sheldon & Lei Shi & Consuelo Martinez & Jie Zhang & Annie Tian & Yutong Sun & Shinichi Nakagawa & Fan Yao & Hai Wang & Li Ma
1-20 Genomic and transcriptomic landscape of human gastrointestinal stromal tumors
by Feifei Xie & Shuzhen Luo & Dongbing Liu & Xiaojing Lu & Ming Wang & Xiaoxiao Liu & Fujian Jia & Yuzhi Pang & Yanying Shen & Chunling Zeng & Xinli Ma & Daoqiang Tang & Lin Tu & Linxi Yang & Yumei Cheng & Yuxiang Luo & Fanfan Xie & Hao Hou & Tao Huang & Bo Ni & Chun Zhuang & Wenyi Zhao & Ke Li & Xufen Zheng & Wenbo Bi & Xiaona Jia & Yi He & Simin Wang & Hui Cao & Kui Wu & Yuexiang Wang
1-20 Loss of cold tolerance is conferred by absence of the WRKY34 promoter fragment during tomato evolution
by Mingyue Guo & Fengjun Yang & Lijuan Zhu & Leilei Wang & Zhichao Li & Zhenyu Qi & Vasileios Fotopoulos & Jingquan Yu & Jie Zhou
1-20 The secreted protein Amuc_1409 from Akkermansia muciniphila improves gut health through intestinal stem cell regulation
by Eun-Jung Kang & Jae-Hoon Kim & Young Eun Kim & Hana Lee & Kwang Bo Jung & Dong-Ho Chang & Youngjin Lee & Shinhye Park & Eun-Young Lee & Eun-Ji Lee & Ho Bum Kang & Moon-Young Rhyoo & Seungwoo Seo & Sohee Park & Yubin Huh & Jun Go & Jung Hyeon Choi & Young-Keun Choi & In-Bok Lee & Dong-Hee Choi & Yun Jeong Seo & Jung-Ran Noh & Kyoung-Shim Kim & Jung Hwan Hwang & Ji-Seon Jeong & Ha-Jeong Kwon & Hee Min Yoo & Mi-Young Son & Yeon-Gu Kim & Dae-Hee Lee & Tae-Young Kim & Hyo-Jung Kwon & Myung Hee Kim & Byoung-Chan Kim & Yong-Hoon Kim & Dukjin Kang & Chul-Ho Lee
1-20 scCAD: Cluster decomposition-based anomaly detection for rare cell identification in single-cell expression data
by Yunpei Xu & Shaokai Wang & Qilong Feng & Jiazhi Xia & Yaohang Li & Hong-Dong Li & Jianxin Wang
1-20 Nuclear IMPDH2 controls the DNA damage response by modulating PARP1 activity
by Lorena Espinar & Marta Garcia-Cao & Alisa Schmidt & Savvas Kourtis & Antoni Gañez Zapater & Carla Aranda-Vallejo & Ritobrata Ghose & Laura Garcia-Lopez & Ilir Sheraj & Natalia Pardo-Lorente & Marina Bantulà & Laura Pascual-Reguant & Evangelia Darai & Maria Guirola & Joan Montero & Sara Sdelci
1-20 Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow
by Tongling Huang & Zhaocheng Lu & Zihui Wang & Lixin Cheng & Lu Gao & Jun Gao & Ning Zhang & Chang-An Geng & Xiaoli Zhao & Huaiyu Wang & Chi-Wai Wong & Kelvin W. K. Yeung & Haobo Pan & William Weijia Lu & Min Guan
1-20 Structuring lipid nanoparticles, DNA, and protein corona into stealth bionanoarchitectures for in vivo gene delivery
by Serena Renzi & Luca Digiacomo & Daniela Pozzi & Erica Quagliarini & Elisabetta Vulpis & Maria Valeria Giuli & Angelica Mancusi & Bianca Natiello & Maria Gemma Pignataro & Gianluca Canettieri & Laura Magno & Luca Pesce & Valentina Lorenzi & Samuele Ghignoli & Luisa Loconte & Carmela Maria Montone & Anna Laura Capriotti & Aldo Laganà & Carmine Nicoletti & Heinz Amenitsch & Marco Rossi & Francesco Mura & Giacomo Parisi & Francesco Cardarelli & Alessandra Zingoni & Saula Checquolo & Giulio Caracciolo
1-20 BET inhibitors drive Natural Killer activation in non-small cell lung cancer via BRD4 and SMAD3
by Francesca Reggiani & Giovanna Talarico & Giulia Gobbi & Elisabetta Sauta & Federica Torricelli & Veronica Manicardi & Eleonora Zanetti & Stefania Orecchioni & Paolo Falvo & Simonetta Piana & Filippo Lococo & Massimiliano Paci & Francesco Bertolini & Alessia Ciarrocchi & Valentina Sancisi
1-20 Tissue niche influences immune and metabolic profiles to Staphylococcus aureus biofilm infection
by Zachary Roy & Prabakar Arumugam & Blake P. Bertrand & Dhananjay D. Shinde & Vinai C. Thomas & Tammy Kielian
1-20 Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis
by Heather J. Faust & Tan-Yun Cheng & Ilya Korsunsky & Gerald F. M. Watts & Shani T. Gal-Oz & William V. Trim & Suppawat Kongthong & Anna Helena Jonsson & Daimon P. Simmons & Fan Zhang & Robert Padera & Susan Chubinskaya & Kevin Wei & Soumya Raychaudhuri & Lydia Lynch & D. Branch Moody & Michael B. Brenner
1-20 A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds
by Ming Li & Chenxi Wang & Qiang Yu & Haoyi Chen & Yingying Ma & Li Wei & Mei X. Wu & Min Yao & Min Lu
1-20 Mitochondrial network reorganization and transient expansion during oligodendrocyte generation
by Xhoela Bame & Robert A. Hill
1-20 HRDE-2 drives small RNA specificity for the nuclear Argonaute protein HRDE-1
by Shihui Chen & Carolyn M. Phillips
1-20 Gut microbiome remodeling and metabolomic profile improves in response to protein pacing with intermittent fasting versus continuous caloric restriction
by Alex E. Mohr & Karen L. Sweazea & Devin A. Bowes & Paniz Jasbi & Corrie M. Whisner & Dorothy D. Sears & Rosa Krajmalnik-Brown & Yan Jin & Haiwei Gu & Judith Klein-Seetharaman & Karen M. Arciero & Eric Gumpricht & Paul J. Arciero
1-20 mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism
by Tal Levy & Kai Voeltzke & Laura Hruby & Khawla Alasad & Zuelal Bas & Marteinn Snaebjörnsson & Ran Marciano & Katerina Scharov & Mélanie Planque & Kim Vriens & Stefan Christen & Cornelius M. Funk & Christina Hassiepen & Alisa Kahler & Beate Heider & Daniel Picard & Jonathan K. M. Lim & Anja Stefanski & Katja Bendrin & Andres Vargas-Toscano & Ulf D. Kahlert & Kai Stühler & Marc Remke & Moshe Elkabets & Thomas G. P. Grünewald & Andreas S. Reichert & Sarah-Maria Fendt & Almut Schulze & Guido Reifenberger & Barak Rotblat & Gabriel Leprivier
1-20 MMP-2-triggered, mitochondria-targeted PROTAC-PDT therapy of breast cancer and brain metastases inhibition
by Fan Tong & Yufan Wang & Yanyan Xu & Yang Zhou & Siqin He & Yufan Du & Wenqin Yang & Ting Lei & Yujun Song & Tao Gong & Huile Gao
1-20 Proteomic landscape of epithelial ovarian cancer
by Liujia Qian & Jianqing Zhu & Zhangzhi Xue & Yan Zhou & Nan Xiang & Hong Xu & Rui Sun & Wangang Gong & Xue Cai & Lu Sun & Weigang Ge & Yufeng Liu & Ying Su & Wangmin Lin & Yuecheng Zhan & Junjian Wang & Shuang Song & Xiao Yi & Maowei Ni & Yi Zhu & Yuejin Hua & Zhiguo Zheng & Tiannan Guo
1-20 Polymeric nanocarrier via metabolism regulation mediates immunogenic cell death with spatiotemporal orchestration for cancer immunotherapy
by Yichen Guo & Yongjuan Li & Mengzhe Zhang & Rong Ma & Yayun Wang & Xiao Weng & Jinjie Zhang & Zhenzhong Zhang & Xiaoyuan Chen & Weijing Yang
1-20 Single-cell transcriptomics reveal transcriptional programs underlying male and female cell fate during Plasmodium falciparum gametocytogenesis
by Mubasher Mohammed & Alexis Dziedziech & Diego Macedo & Frederik Huppertz & Ylva Veith & Zoé Postel & Elena Christ & Richard Scheytt & Tanja Slotte & Johan Henriksson & Johan Ankarklev
1-20 Two KaiABC systems control circadian oscillations in one cyanobacterium
by Christin Köbler & Nicolas M. Schmelling & Anika Wiegard & Alice Pawlowski & Gopal K. Pattanayak & Philipp Spät & Nina M. Scheurer & Kim N. Sebastian & Florian P. Stirba & Lutz C. Berwanger & Petra Kolkhof & Boris Maček & Michael J. Rust & Ilka M. Axmann & Annegret Wilde
1-20 Defective mitochondria remodelling in B cells leads to an aged immune response
by Marta Iborra-Pernichi & Jonathan Ruiz García & María Velasco de la Esperanza & Belén S. Estrada & Elena R. Bovolenta & Claudia Cifuentes & Cristina Prieto Carro & Tamara González Martínez & José García-Consuegra & María Fernanda Rey-Stolle & Francisco Javier Rupérez & Milagros Guerra Rodriguez & Rafael J. Argüello & Sara Cogliati & Fernando Martín-Belmonte & Nuria Martínez-Martín
1-20 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase
by Benoît Arragain & Tim Krischuns & Martin Pelosse & Petra Drncova & Martin Blackledge & Nadia Naffakh & Stephen Cusack
1-20 Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers
by Yifan Li & Kai Shao & Zhaoxing Li & Kongfu Zhu & Bee Koon Gan & Jian Shi & Yibei Xiao & Min Luo
1-20 QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration
by Jayshree Advani & Puja A. Mehta & Andrew R. Hamel & Sudeep Mehrotra & Christina Kiel & Tobias Strunz & Ximena Corso-Díaz & Madeline Kwicklis & Freekje Asten & Rinki Ratnapriya & Emily Y. Chew & Dena G. Hernandez & Sandra R. Montezuma & Deborah A. Ferrington & Bernhard H. F. Weber & Ayellet V. Segrè & Anand Swaroop
1-20 Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins
by Tom J. Arrowsmith & Xibing Xu & Shangze Xu & Ben Usher & Peter Stokes & Megan Guest & Agnieszka K. Bronowska & Pierre Genevaux & Tim R. Blower

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December 2024, Volume 15, Issue 1

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