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The parasitic lifestyle of an archaeal symbiont

Author

Listed:
  • Joshua N. Hamm

    (UNSW Sydney
    Royal Netherlands Institute for Sea Research)

  • Yan Liao

    (University of Technology Sydney)

  • Andriko Kügelgen

    (MRC Laboratory of Molecular Biology
    University of Oxford)

  • Nina Dombrowski

    (Royal Netherlands Institute for Sea Research)

  • Evan Landers

    (UNSW Sydney)

  • Christopher Brownlee

    (University of New South Wales
    University of Wollongong)

  • Emma M. V. Johansson

    (University of New South Wales)

  • Renee M. Whan

    (The University of New South Wales)

  • Matthew A. B. Baker

    (UNSW Sydney)

  • Buzz Baum

    (MRC Laboratory of Molecular Biology)

  • Tanmay A. M. Bharat

    (MRC Laboratory of Molecular Biology
    University of Oxford)

  • Iain G. Duggin

    (University of Technology Sydney)

  • Anja Spang

    (Royal Netherlands Institute for Sea Research
    University of Amsterdam)

  • Ricardo Cavicchioli

    (UNSW Sydney)

Abstract

DPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the host species are poorly understood. Here, we show that a DPANN archaeon (Candidatus Nanohaloarchaeum antarcticus) engages in parasitic interactions with its host (Halorubrum lacusprofundi) that result in host cell lysis. During these interactions, the nanohaloarchaeon appears to enter, or be engulfed by, the host cell. Our results provide experimental evidence for a predatory-like lifestyle of an archaeon, suggesting that at least some DPANN archaea may have roles in controlling host populations and their ecology.

Suggested Citation

  • Joshua N. Hamm & Yan Liao & Andriko Kügelgen & Nina Dombrowski & Evan Landers & Christopher Brownlee & Emma M. V. Johansson & Renee M. Whan & Matthew A. B. Baker & Buzz Baum & Tanmay A. M. Bharat & Ia, 2024. "The parasitic lifestyle of an archaeal symbiont," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-49962-y
    DOI: 10.1038/s41467-024-49962-y
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    References listed on IDEAS

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