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The parasitic lifestyle of an archaeal symbiont

Author

Listed:
  • Joshua N. Hamm

    (UNSW Sydney
    Royal Netherlands Institute for Sea Research)

  • Yan Liao

    (University of Technology Sydney)

  • Andriko Kügelgen

    (MRC Laboratory of Molecular Biology
    University of Oxford)

  • Nina Dombrowski

    (Royal Netherlands Institute for Sea Research)

  • Evan Landers

    (UNSW Sydney)

  • Christopher Brownlee

    (University of New South Wales
    University of Wollongong)

  • Emma M. V. Johansson

    (University of New South Wales)

  • Renee M. Whan

    (The University of New South Wales)

  • Matthew A. B. Baker

    (UNSW Sydney)

  • Buzz Baum

    (MRC Laboratory of Molecular Biology)

  • Tanmay A. M. Bharat

    (MRC Laboratory of Molecular Biology
    University of Oxford)

  • Iain G. Duggin

    (University of Technology Sydney)

  • Anja Spang

    (Royal Netherlands Institute for Sea Research
    University of Amsterdam)

  • Ricardo Cavicchioli

    (UNSW Sydney)

Abstract

DPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the host species are poorly understood. Here, we show that a DPANN archaeon (Candidatus Nanohaloarchaeum antarcticus) engages in parasitic interactions with its host (Halorubrum lacusprofundi) that result in host cell lysis. During these interactions, the nanohaloarchaeon appears to enter, or be engulfed by, the host cell. Our results provide experimental evidence for a predatory-like lifestyle of an archaeon, suggesting that at least some DPANN archaea may have roles in controlling host populations and their ecology.

Suggested Citation

  • Joshua N. Hamm & Yan Liao & Andriko Kügelgen & Nina Dombrowski & Evan Landers & Christopher Brownlee & Emma M. V. Johansson & Renee M. Whan & Matthew A. B. Baker & Buzz Baum & Tanmay A. M. Bharat & Ia, 2024. "The parasitic lifestyle of an archaeal symbiont," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-49962-y
    DOI: 10.1038/s41467-024-49962-y
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    References listed on IDEAS

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    1. Susanne Krause & Sabrina Gfrerer & Andriko Kügelgen & Carsten Reuse & Nina Dombrowski & Laura Villanueva & Boyke Bunk & Cathrin Spröer & Thomas R. Neu & Ute Kuhlicke & Kerstin Schmidt-Hohagen & Karste, 2022. "The importance of biofilm formation for cultivation of a Micrarchaeon and its interactions with its Thermoplasmatales host," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
    2. Nina Dombrowski & Tom A. Williams & Jiarui Sun & Benjamin J. Woodcroft & Jun-Hoe Lee & Bui Quang Minh & Christian Rinke & Anja Spang, 2020. "Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution," Nature Communications, Nature, vol. 11(1), pages 1-15, December.
    3. Harald Huber & Michael J. Hohn & Reinhard Rachel & Tanja Fuchs & Verena C. Wimmer & Karl O. Stetter, 2002. "A new phylum of Archaea represented by a nanosized hyperthermophilic symbiont," Nature, Nature, vol. 417(6884), pages 63-67, May.
    4. Olga V. Golyshina & Stepan V. Toshchakov & Kira S. Makarova & Sergey N. Gavrilov & Aleksei A. Korzhenkov & Violetta La Cono & Erika Arcadi & Taras Y. Nechitaylo & Manuel Ferrer & Ilya V. Kublanov & Yu, 2017. "‘ARMAN’ archaea depend on association with euryarchaeal host in culture and in situ," Nature Communications, Nature, vol. 8(1), pages 1-12, December.
    5. Renée Kapteijn & Shraddha Shitut & Dennis Aschmann & Le Zhang & Marit Beer & Deniz Daviran & Rona Roverts & Anat Akiva & Gilles P. Wezel & Alexander Kros & Dennis Claessen, 2022. "Endocytosis-like DNA uptake by cell wall-deficient bacteria," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    6. Louie Wurch & Richard J. Giannone & Bernard S. Belisle & Carolyn Swift & Sagar Utturkar & Robert L. Hettich & Anna-Louise Reysenbach & Mircea Podar, 2016. "Genomics-informed isolation and characterization of a symbiotic Nanoarchaeota system from a terrestrial geothermal environment," Nature Communications, Nature, vol. 7(1), pages 1-10, November.
    7. David Moreira & Yvan Zivanovic & Ana I. López-Archilla & Miguel Iniesto & Purificación López-García, 2021. "Reductive evolution and unique predatory mode in the CPR bacterium Vampirococcus lugosii," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
    8. Iain G. Duggin & Christopher H. S. Aylett & James C. Walsh & Katharine A. Michie & Qing Wang & Lynne Turnbull & Emma M. Dawson & Elizabeth J. Harry & Cynthia B. Whitchurch & Linda A. Amos & Jan Löwe, 2015. "CetZ tubulin-like proteins control archaeal cell shape," Nature, Nature, vol. 519(7543), pages 362-365, March.
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