Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-023-44209-8
Download full text from publisher
References listed on IDEAS
- Alain R. Weber & Claudia Krawczyk & Adam B. Robertson & Anna Kuśnierczyk & Cathrine B. Vågbø & David Schuermann & Arne Klungland & Primo Schär, 2016. "Biochemical reconstitution of TET1–TDG–BER-dependent active DNA demethylation reveals a highly coordinated mechanism," Nature Communications, Nature, vol. 7(1), pages 1-13, April.
- Marcin J. Suskiewicz & Florian Zobel & Tom E. H. Ogden & Pietro Fontana & Antonio Ariza & Ji-Chun Yang & Kang Zhu & Lily Bracken & William J. Hawthorne & Dragana Ahel & David Neuhaus & Ivan Ahel, 2020. "HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation," Nature, Nature, vol. 579(7800), pages 598-602, March.
- Huifen Cao & Lorena Salazar-García & Fan Gao & Thor Wahlestedt & Chun-Lin Wu & Xueer Han & Ye Cai & Dongyang Xu & Fang Wang & Lu Tang & Natalie Ricciardi & DingDing Cai & Huifang Wang & Mario P. S. Ch, 2019. "Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Hana Hanzlikova & Evgeniia Prokhorova & Katerina Krejcikova & Zuzana Cihlarova & Ilona Kalasova & Jan Kubovciak & Jana Sachova & Richard Hailstone & Jan Brazina & Shereen Ghosh & Sebahattin Cirak & Jo, 2020. "Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
- Annika Krüger & Alexander Bürkle & Karin Hauser & Aswin Mangerich, 2020. "Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy," Nature Communications, Nature, vol. 11(1), pages 1-15, December.
- Clifford D. Mol & Tadahide Izumi & Sankar Mitra & John A. Tainer, 2000. "DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination," Nature, Nature, vol. 403(6768), pages 451-456, January.
- George E. Ronson & Ann Liza Piberger & Martin R. Higgs & Anna L. Olsen & Grant S. Stewart & Peter J. McHugh & Eva Petermann & Nicholas D. Lakin, 2018. "PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
- Wei Wu & Sarah E. Hill & William J. Nathan & Jacob Paiano & Elsa Callen & Dongpeng Wang & Kenta Shinoda & Niek Wietmarschen & Jennifer M. Colón-Mercado & Dali Zong & Raffaella Pace & Han-Yu Shih & Ste, 2021. "Neuronal enhancers are hotspots for DNA single-strand break repair," Nature, Nature, vol. 593(7859), pages 440-444, May.
- Paul Adrian Ginno & Dimos Gaidatzis & Angelika Feldmann & Leslie Hoerner & Dilek Imanci & Lukas Burger & Frederic Zilbermann & Antoine H. F. M. Peters & Frank Edenhofer & Sébastien A. Smallwood & Arna, 2020. "A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity," Nature Communications, Nature, vol. 11(1), pages 1-16, December.
- Clifford D. Mol & Tadahide Izumi & Sankar Mitra & John A. Tainer, 2000. "Erratum: DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination," Nature, Nature, vol. 404(6777), pages 525-525, March.
- Rahul M. Kohli & Yi Zhang, 2013. "TET enzymes, TDG and the dynamics of DNA demethylation," Nature, Nature, vol. 502(7472), pages 472-479, October.
- Stephen J. Pettitt & Dragomir B. Krastev & Inger Brandsma & Amy Dréan & Feifei Song & Radoslav Aleksandrov & Maria I. Harrell & Malini Menon & Rachel Brough & James Campbell & Jessica Frankum & Michae, 2018. "Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance," Nature Communications, Nature, vol. 9(1), pages 1-14, December.
Citations
Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
Cited by:
- Luc Provencher & Wilson Nartey & Peter M. Brownlee & Austin W. Atkins & Jean-Philippe Gagné & Lou Baudrier & Nicholas S. Y. Ting & Cortt G. Piett & Shujuan Fang & Dustin D. Pearson & Shaun Moore & Pie, 2025. "CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair," Nature Communications, Nature, vol. 16(1), pages 1-24, December.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Ivo A. Hendriks & Sara C. Buch-Larsen & Evgeniia Prokhorova & Jonas D. Elsborg & Alexandra K.L.F.S. Rebak & Kang Zhu & Dragana Ahel & Claudia Lukas & Ivan Ahel & Michael L. Nielsen, 2021. "The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
- Lina Wang & Siru Li & Kai Wang & Na Wang & Qiaoling Liu & Zhen Sun & Li Wang & Lulu Wang & Quentin Liu & Chengli Song & Caigang Liu & Qingkai Yang, 2022. "DNA mechanical flexibility controls DNA potential to activate cGAS-mediated immune surveillance," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
- Pietro Fontana & Sara C. Buch-Larsen & Osamu Suyari & Rebecca Smith & Marcin J. Suskiewicz & Kira Schützenhofer & Antonio Ariza & Johannes Gregor Matthias Rack & Michael L. Nielsen & Ivan Ahel, 2023. "Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Frederick Richards & Marta J. Llorca-Cardenosa & Jamie Langton & Sara C. Buch-Larsen & Noor F. Shamkhi & Abhishek Bharadwaj Sharma & Michael L. Nielsen & Nicholas D. Lakin, 2023. "Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- Ye Cai & Huifen Cao & Fang Wang & Yufei Zhang & Philipp Kapranov, 2022. "Complex genomic patterns of abasic sites in mammalian DNA revealed by a high-resolution SSiNGLe-AP method," Nature Communications, Nature, vol. 13(1), pages 1-21, December.
- Haichao Zhao & Jia Li & Zhongsheng You & Howard D. Lindsay & Shan Yan, 2024. "Distinct regulation of ATM signaling by DNA single-strand breaks and APE1," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Tyler M. Weaver & Nicole M. Hoitsma & Jonah J. Spencer & Lokesh Gakhar & Nicholas J. Schnicker & Bret D. Freudenthal, 2022. "Structural basis for APE1 processing DNA damage in the nucleosome," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Umeshkumar Vekariya & Leonid Minakhin & Gurushankar Chandramouly & Mrityunjay Tyagi & Tatiana Kent & Katherine Sullivan-Reed & Jessica Atkins & Douglas Ralph & Margaret Nieborowska-Skorska & Anna-Mari, 2024. "PARG is essential for Polθ-mediated DNA end-joining by removing repressive poly-ADP-ribose marks," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Giordano Reginato & Maria Rosaria Dello Stritto & Yanbo Wang & Jingzhou Hao & Raphael Pavani & Michael Schmitz & Swagata Halder & Vincent Morin & Elda Cannavo & Ilaria Ceppi & Stefan Braunshier & Anan, 2024. "HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Zita Fábián & Ellen S. Kakulidis & Ivo A. Hendriks & Ulrike Kühbacher & Nicolai B. Larsen & Marta Oliva-Santiago & Junhui Wang & Xueyuan Leng & A. Barbara Dirac-Svejstrup & Jesper Q. Svejstrup & Micha, 2024. "PARP1-dependent DNA-protein crosslink repair," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Luka Bacic & Guillaume Gaullier & Jugal Mohapatra & Guanzhong Mao & Klaus Brackmann & Mikhail Panfilov & Glen Liszczak & Anton Sabantsev & Sebastian Deindl, 2024. "Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
- Allegra Angeloni & Skye Fissette & Deniz Kaya & Jillian M. Hammond & Hasindu Gamaarachchi & Ira W. Deveson & Robert J. Klose & Weiming Li & Xiaotian Zhang & Ozren Bogdanovic, 2024. "Extensive DNA methylome rearrangement during early lamprey embryogenesis," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Steffen Mueller & Gail Dennison & Shujun Liu, 2021. "An Assessment on Ethanol-Blended Gasoline/Diesel Fuels on Cancer Risk and Mortality," IJERPH, MDPI, vol. 18(13), pages 1-23, June.
- Marie-France Langelier & Ramya Billur & Aleksandr Sverzhinsky & Ben E. Black & John M. Pascal, 2021. "HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
- Anchel de Jaime-Soguero & Janina Hattemer & Anja Bufe & Alexander Haas & Jeroen Berg & Vincent Batenburg & Biswajit Das & Barbara Marco & Stefania Androulaki & Nicolas Böhly & Jonathan J. M. Landry & , 2024. "Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress," Nature Communications, Nature, vol. 15(1), pages 1-22, December.
- Charlotte Blessing & Katja Apelt & Diana Heuvel & Claudia Gonzalez-Leal & Magdalena B. Rother & Melanie Woude & Román González-Prieto & Adi Yifrach & Avital Parnas & Rashmi G. Shah & Tia Tyrsett Kuo &, 2022. "XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
- Yidong Song & Qianmu Yuan & Sheng Chen & Yuansong Zeng & Huiying Zhao & Yuedong Yang, 2024. "Accurately predicting enzyme functions through geometric graph learning on ESMFold-predicted structures," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
- Ozge Saatci & Metin Cetin & Meral Uner & Unal Metin Tokat & Ioulia Chatzistamou & Pelin Gulizar Ersan & Elodie Montaudon & Aytekin Akyol & Sercan Aksoy & Aysegul Uner & Elisabetta Marangoni & Mathew S, 2023. "Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
- Yanbo Wang & W. Taylor Cottle & Haobo Wang & Momcilo Gavrilov & Roger S. Zou & Minh-Tam Pham & Srinivasan Yegnasubramanian & Scott Bailey & Taekjip Ha, 2022. "Achieving single nucleotide sensitivity in direct hybridization genome imaging," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
- Luc Provencher & Wilson Nartey & Peter M. Brownlee & Austin W. Atkins & Jean-Philippe Gagné & Lou Baudrier & Nicholas S. Y. Ting & Cortt G. Piett & Shujuan Fang & Dustin D. Pearson & Shaun Moore & Pie, 2025. "CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair," Nature Communications, Nature, vol. 16(1), pages 1-24, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-023-44209-8. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.