A polygenic score method boosted by non-additive models
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DOI: 10.1038/s41467-024-48654-x
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- Tian Ge & Chia-Yen Chen & Yang Ni & Yen-Chen Anne Feng & Jordan W. Smoller, 2019. "Polygenic prediction via Bayesian regression and continuous shrinkage priors," Nature Communications, Nature, vol. 10(1), pages 1-10, December.
- Lam C. Tsoi & Philip E. Stuart & Chao Tian & Johann E. Gudjonsson & Sayantan Das & Matthew Zawistowski & Eva Ellinghaus & Jonathan N. Barker & Vinod Chandran & Nick Dand & Kristina Callis Duffin & Cha, 2017. "Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants," Nature Communications, Nature, vol. 8(1), pages 1-8, August.
- Clare Bycroft & Colin Freeman & Desislava Petkova & Gavin Band & Lloyd T. Elliott & Kevin Sharp & Allan Motyer & Damjan Vukcevic & Olivier Delaneau & Jared O’Connell & Adrian Cortes & Samantha Welsh &, 2018. "The UK Biobank resource with deep phenotyping and genomic data," Nature, Nature, vol. 562(7726), pages 203-209, October.
- Junyang Qian & Yosuke Tanigawa & Wenfei Du & Matthew Aguirre & Chris Chang & Robert Tibshirani & Manuel A Rivas & Trevor Hastie, 2020. "A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank," PLOS Genetics, Public Library of Science, vol. 16(10), pages 1-30, October.
- Fredrick R. Schumacher & Stephanie L. Schmit & Shuo Jiao & Christopher K. Edlund & Hansong Wang & Ben Zhang & Li Hsu & Shu-Chen Huang & Christopher P. Fischer & John F. Harju & Gregory E. Idos & Flavi, 2015. "Genome-wide association study of colorectal cancer identifies six new susceptibility loci," Nature Communications, Nature, vol. 6(1), pages 1-7, November.
- Luke R. Lloyd-Jones & Jian Zeng & Julia Sidorenko & Loïc Yengo & Gerhard Moser & Kathryn E. Kemper & Huanwei Wang & Zhili Zheng & Reedik Magi & Tõnu Esko & Andres Metspalu & Naomi R. Wray & Michael E., 2019. "Improved polygenic prediction by Bayesian multiple regression on summary statistics," Nature Communications, Nature, vol. 10(1), pages 1-11, December.
- Fredrick R. Schumacher & Stephanie L. Schmit & Shuo Jiao & Christopher K. Edlund & Hansong Wang & Ben Zhang & Li Hsu & Shu-Chen Huang & Christopher P. Fischer & John F. Harju & Gregory E. Idos & Flavi, 2015. "Correction: Corrigendum: Genome-wide association study of colorectal cancer identifies six new susceptibility loci," Nature Communications, Nature, vol. 6(1), pages 1-1, December.
- John G. Cragg & Russell S. Uhler, 1970. "The Demand for Automobiles," Canadian Journal of Economics, Canadian Economics Association, vol. 3(3), pages 386-406, August.
- Yosuke Tanigawa & Junyang Qian & Guhan Venkataraman & Johanne Marie Justesen & Ruilin Li & Robert Tibshirani & Trevor Hastie & Manuel A Rivas, 2022. "Significant sparse polygenic risk scores across 813 traits in UK Biobank," PLOS Genetics, Public Library of Science, vol. 18(3), pages 1-21, March.
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