Content
August 2016, Volume 536, Issue 7617
- 387-387 Obama’s science legacy: climate (policy) hots up
by Jeff Tollefson - 388-390 Busting the billion-dollar myth: how to slash the cost of drug development
by Amy Maxmen - 391-393 Expand the frontiers of urban sustainability
by David Wachsmuth & Daniel Aldana Cohen & Hillary Angelo - 394-395 In retrospect: Flowers for Algernon
by Ananyo Bhattacharya - 395-395 Books in brief
by Barbara Kiser - 396-396 Social changes affect water quality too
by Alec Rolston - 396-396 Venezuela's brain drain is accelerating
by Jaime Requena - 396-396 Stop marginalizing rare syndromes
by Svein Olav Kolset - 396-396 Don't let climate crush coral efforts
by Jennifer McGowan & Hugh P. Possingham & Ken Anthony - 396-396 Strengthen China's flood control
by Yang Zhou & Yansui Liu & Wenxiang Wu - 397-397 Alfred G. Knudson (1922–2016)
by Carlo M. Croce - 400-401 Generation soft
by Barbara Mazzolai & Virgilio Mattoli - 401-402 Friendly neighbours feed tumour cells
by Jurre J. Kamphorst & Eyal Gottlieb - 402-404 Signal locked in
by Kimberley C. Snowden & Bart J. Janssen - 404-405 Fleeting glimpse of an elusive element
by Thomas E. Albrecht-Schmitt - 405-406 Memories linked within a window of time
by Howard Eichenbaum - 407-408 Mitotic regulation comes into focus
by David O. Morgan - 408-409 Earth-like planet around Sun's neighbour
by Artie P. Hatzes - 411-418 Early onset of industrial-era warming across the oceans and continents
by Nerilie J. Abram & Helen V. McGregor & Jessica E. Tierney & Michael N. Evans & Nicholas P. McKay & Darrell S. Kaufman - 419-424 Genomic insights into the origin of farming in the ancient Near East
by Iosif Lazaridis & Dani Nadel & Gary Rollefson & Deborah C. Merrett & Nadin Rohland & Swapan Mallick & Daniel Fernandes & Mario Novak & Beatriz Gamarra & Kendra Sirak & Sarah Connell & Kristin Stewardson & Eadaoin Harney & Qiaomei Fu & Gloria Gonzalez-Fortes & Eppie R. Jones & Songül Alpaslan Roodenberg & György Lengyel & Fanny Bocquentin & Boris Gasparian & Janet M. Monge & Michael Gregg & Vered Eshed & Ahuva-Sivan Mizrahi & Christopher Meiklejohn & Fokke Gerritsen & Luminita Bejenaru & Matthias Blüher & Archie Campbell & Gianpiero Cavalleri & David Comas & Philippe Froguel & Edmund Gilbert & Shona M. Kerr & Peter Kovacs & Johannes Krause & Darren McGettigan & Michael Merrigan & D. Andrew Merriwether & Seamus O'Reilly & Martin B. Richards & Ornella Semino & Michel Shamoon-Pour & Gheorghe Stefanescu & Michael Stumvoll & Anke Tönjes & Antonio Torroni & James F. Wilson & Loic Yengo & Nelli A. Hovhannisyan & Nick Patterson & Ron Pinhasi & David Reich - 425-430 Uncovering Earth’s virome
by David Paez-Espino & Emiley A. Eloe-Fadrosh & Georgios A. Pavlopoulos & Alex D. Thomas & Marcel Huntemann & Natalia Mikhailova & Edward Rubin & Natalia N. Ivanova & Nikos C. Kyrpides - 431-436 Molecular basis of APC/C regulation by the spindle assembly checkpoint
by Claudio Alfieri & Leifu Chang & Ziguo Zhang & Jing Yang & Sarah Maslen & Mark Skehel & David Barford - 437-440 A terrestrial planet candidate in a temperate orbit around Proxima Centauri
by Guillem Anglada-Escudé & Pedro J. Amado & John Barnes & Zaira M. Berdiñas & R. Paul Butler & Gavin A. L. Coleman & Ignacio de la Cueva & Stefan Dreizler & Michael Endl & Benjamin Giesers & Sandra V. Jeffers & James S. Jenkins & Hugh R. A. Jones & Marcin Kiraga & Martin Kürster & Marίa J. López-González & Christopher J. Marvin & Nicolás Morales & Julien Morin & Richard P. Nelson & José L. Ortiz & Aviv Ofir & Sijme-Jan Paardekooper & Ansgar Reiners & Eloy Rodríguez & Cristina Rodrίguez-López & Luis F. Sarmiento & John P. Strachan & Yiannis Tsapras & Mikko Tuomi & Mathias Zechmeister - 441-445 Extending the lifetime of a quantum bit with error correction in superconducting circuits
by Nissim Ofek & Andrei Petrenko & Reinier Heeres & Philip Reinhold & Zaki Leghtas & Brian Vlastakis & Yehan Liu & Luigi Frunzio & S. M. Girvin & L. Jiang & Mazyar Mirrahimi & M. H. Devoret & R. J. Schoelkopf - 446-450 Molecular modifiers reveal a mechanism of pathological crystal growth inhibition
by Jihae Chung & Ignacio Granja & Michael G. Taylor & Giannis Mpourmpakis & John R. Asplin & Jeffrey D. Rimer - 451-455 An integrated design and fabrication strategy for entirely soft, autonomous robots
by Michael Wehner & Ryan L. Truby & Daniel J. Fitzgerald & Bobak Mosadegh & George M. Whitesides & Jennifer A. Lewis & Robert J. Wood - 456-459 Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality
by Santiago Soliveres & Fons van der Plas & Peter Manning & Daniel Prati & Martin M. Gossner & Swen C. Renner & Fabian Alt & Hartmut Arndt & Vanessa Baumgartner & Julia Binkenstein & Klaus Birkhofer & Stefan Blaser & Nico Blüthgen & Steffen Boch & Stefan Böhm & Carmen Börschig & Francois Buscot & Tim Diekötter & Johannes Heinze & Norbert Hölzel & Kirsten Jung & Valentin H. Klaus & Till Kleinebecker & Sandra Klemmer & Jochen Krauss & Markus Lange & E. Kathryn Morris & Jörg Müller & Yvonne Oelmann & Jörg Overmann & Esther Pašalić & Matthias C. Rillig & H. Martin Schaefer & Michael Schloter & Barbara Schmitt & Ingo Schöning & Marion Schrumpf & Johannes Sikorski & Stephanie A. Socher & Emily F. Solly & Ilja Sonnemann & Elisabeth Sorkau & Juliane Steckel & Ingolf Steffan-Dewenter & Barbara Stempfhuber & Marco Tschapka & Manfred Türke & Paul C. Venter & Christiane N. Weiner & Wolfgang W. Weisser & Michael Werner & Catrin Westphal & Wolfgang Wilcke & Volkmar Wolters & Tesfaye Wubet & Susanne Wurst & Markus Fischer & Eric Allan - 460-463 The TRPM2 ion channel is required for sensitivity to warmth
by Chun-Hsiang Tan & Peter A. McNaughton - 464-468 The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6
by Alexander Küffer & Asvin K. K. Lakkaraju & Amit Mogha & Sarah C. Petersen & Kristina Airich & Cédric Doucerain & Rajlakshmi Marpakwar & Pamela Bakirci & Assunta Senatore & Arnaud Monnard & Carmen Schiavi & Mario Nuvolone & Bianka Grosshans & Simone Hornemann & Frederic Bassilana & Kelly R. Monk & Adriano Aguzzi - 469-473 DWARF14 is a non-canonical hormone receptor for strigolactone
by Ruifeng Yao & Zhenhua Ming & Liming Yan & Suhua Li & Fei Wang & Sui Ma & Caiting Yu & Mai Yang & Li Chen & Linhai Chen & Yuwen Li & Chun Yan & Di Miao & Zhongyuan Sun & Jianbin Yan & Yuna Sun & Lei Wang & Jinfang Chu & Shilong Fan & Wei He & Haiteng Deng & Fajun Nan & Jiayang Li & Zihe Rao & Zhiyong Lou & Daoxin Xie - 474-478 Vaccine protection against Zika virus from Brazil
by Rafael A. Larocca & Peter Abbink & Jean Pierre S. Peron & Paolo M. de A. Zanotto & M. Justin Iampietro & Alexander Badamchi-Zadeh & Michael Boyd & David Ng’ang’a & Marinela Kirilova & Ramya Nityanandam & Noe B. Mercado & Zhenfeng Li & Edward T. Moseley & Christine A. Bricault & Erica N. Borducchi & Patricia B. Giglio & David Jetton & George Neubauer & Joseph P. Nkolola & Lori F. Maxfield & Rafael A. De La Barrera & Richard G. Jarman & Kenneth H. Eckels & Nelson L. Michael & Stephen J. Thomas & Dan H. Barouch - 479-483 Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
by Cristovão M. Sousa & Douglas E. Biancur & Xiaoxu Wang & Christopher J. Halbrook & Mara H. Sherman & Li Zhang & Daniel Kremer & Rosa F. Hwang & Agnes K. Witkiewicz & Haoqiang Ying & John M. Asara & Ronald M. Evans & Lewis C. Cantley & Costas A. Lyssiotis & Alec C. Kimmelman - 484-487 Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
by A. J. Venkatakrishnan & Xavier Deupi & Guillaume Lebon & Franziska M. Heydenreich & Tilman Flock & Tamara Miljus & Santhanam Balaji & Michel Bouvier & Dmitry B. Veprintsev & Christopher G. Tate & Gebhard F. X. Schertler & M. Madan Babu - 488-488 Retraction Note: Odour receptors and neurons for DEET and new insect repellents
by Pinky Kain & Sean Michael Boyle & Sana Khalid Tharadra & Tom Guda & Christine Pham & Anupama Dahanukar & Anandasankar Ray - 488-488 Erratum: The bacterial DnaA-trio replication origin element specifies single-stranded DNA initiator binding
by Tomas T. Richardson & Omar Harran & Heath Murray - 488-488 Correction: Corrigendum: Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling
by Zinan Zhou & Alan T. Tang & Weng-Yew Wong & Sharika Bamezai & Lauren M. Goddard & Robert Shenkar & Su Zhou & Jisheng Yang & Alexander C. Wright & Matthew Foley & J. Simon C. Arthur & Kevin J. Whitehead & Issam A. Awad & Dean Y. Li & Xiangjian Zheng & Mark L. Kahn - 489-491 Moonlighting: Dip your toes
by Amy Maxmen - 491-491 Trade talk: Binational liaison
by Monya Baker - 494-494 Interdimensional trade benefits
by Brian Trent
August 2016, Volume 536, Issue 7616
- 251-251 Define the Anthropocene in terms of the whole Earth
by Clive Hamilton - 257-258 Mosquito guns and heavy fines: how Cuba kept Zika at bay for so long
by Sara Reardon - 258-259 Artificial black hole creates its own version of Hawking radiation
by Davide Castelvecchi - 260-260 Nobel laureate’s death highlights struggles at Egyptian science hub
by Pakinam Amer & Mohammed Yahia - 260-261 Trump’s border-wall pledge threatens delicate desert ecosystems
by Brian Owens - 261-262 Morphing neutrinos provide clue to antimatter mystery
by Elizabeth Gibney - 263-265 Bottles, bags, ropes and toothbrushes: the struggle to track ocean plastics
by Daniel Cressey - 266-268 The plastics revolution: how chemists are pushing polymers to new limits
by Mark Peplow - 269-270 Rethink how chemical hazards are tested
by John C. Warner & Jennifer K. Ludwig - 271-272 Ethics: Taming our technologies
by Steven Aftergood - 272-273 Q&A: Brenda Keneghan: The polymer conservator
by Elizabeth Gibney - 273-273 Books in brief
by Barbara Kiser - 274-274 Being more open about PhD papers
by Joy Burrough-Boenisch - 274-274 Music calculations out of tune
by Adrian Goldman - 274-274 World's last in vitro fertilization ban falls
by Felipe Mora-Bermúdez - 274-274 Stop vultures from striking aircraft
by Antoni Margalida - 274-274 Royal Society helps guide Brexit science
by Julie Maxton - 276-277 Sixty years of living polymers
by Gary Patterson - 277-278 A deep dive into genetic variation
by Jay Shendure - 278-280 Flipping the sleep switch
by Stephane Dissel & Paul J. Shaw - 280-281 Elusive active site in focus
by Jay A. Labinger - 281-282 Mechanics drives cell differentiation
by Berenika Plusa & Anna-Katerina Hadjantonakis - 282-283 Superconducting electrons go missing
by Jan Zaanen - 285-291 Analysis of protein-coding genetic variation in 60,706 humans
by Monkol Lek & Konrad J. Karczewski & Eric V. Minikel & Kaitlin E. Samocha & Eric Banks & Timothy Fennell & Anne H. O’Donnell-Luria & James S. Ware & Andrew J. Hill & Beryl B. Cummings & Taru Tukiainen & Daniel P. Birnbaum & Jack A. Kosmicki & Laramie E. Duncan & Karol Estrada & Fengmei Zhao & James Zou & Emma Pierce-Hoffman & Joanne Berghout & David N. Cooper & Nicole Deflaux & Mark DePristo & Ron Do & Jason Flannick & Menachem Fromer & Laura Gauthier & Jackie Goldstein & Namrata Gupta & Daniel Howrigan & Adam Kiezun & Mitja I. Kurki & Ami Levy Moonshine & Pradeep Natarajan & Lorena Orozco & Gina M. Peloso & Ryan Poplin & Manuel A. Rivas & Valentin Ruano-Rubio & Samuel A. Rose & Douglas M. Ruderfer & Khalid Shakir & Peter D. Stenson & Christine Stevens & Brett P. Thomas & Grace Tiao & Maria T. Tusie-Luna & Ben Weisburd & Hong-Hee Won & Dongmei Yu & David M. Altshuler & Diego Ardissino & Michael Boehnke & John Danesh & Stacey Donnelly & Roberto Elosua & Jose C. Florez & Stacey B. Gabriel & Gad Getz & Stephen J. Glatt & Christina M. Hultman & Sekar Kathiresan & Markku Laakso & Steven McCarroll & Mark I. McCarthy & Dermot McGovern & Ruth McPherson & Benjamin M. Neale & Aarno Palotie & Shaun M. Purcell & Danish Saleheen & Jeremiah M. Scharf & Pamela Sklar & Patrick F. Sullivan & Jaakko Tuomilehto & Ming T. Tsuang & Hugh C. Watkins & James G. Wilson & Mark J. Daly & Daniel G. MacArthur - 292-297 Circadian neuron feedback controls the Drosophila sleep–activity profile
by Fang Guo & Junwei Yu & Hyung Jae Jung & Katharine C. Abruzzi & Weifei Luo & Leslie C. Griffith & Michael Rosbash - 298-303 Defining the clonal dynamics leading to mouse skin tumour initiation
by Adriana Sánchez-Danés & Edouard Hannezo & Jean-Christophe Larsimont & Mélanie Liagre & Khalil Kass Youssef & Benjamin D. Simons & Cédric Blanpain - 304-308 Capturing a substrate in an activated RING E3/E2–SUMO complex
by Frederick C. Streich Jr & Christopher D. Lima - 309-311 Dependence of the critical temperature in overdoped copper oxides on superfluid density
by I. Božović & X. He & J. Wu & A. T. Bollinger - 312-316 High-efficiency two-dimensional Ruddlesden–Popper perovskite solar cells
by Hsinhan Tsai & Wanyi Nie & Jean-Christophe Blancon & Constantinos C. Stoumpos & Reza Asadpour & Boris Harutyunyan & Amanda J. Neukirch & Rafael Verduzco & Jared J. Crochet & Sergei Tretiak & Laurent Pedesseau & Jacky Even & Muhammad A. Alam & Gautam Gupta & Jun Lou & Pulickel M. Ajayan & Michael J. Bedzyk & Mercouri G. Kanatzidis & Aditya D. Mohite - 317-321 The active site of low-temperature methane hydroxylation in iron-containing zeolites
by Benjamin E. R. Snyder & Pieter Vanelderen & Max L. Bols & Simon D. Hallaert & Lars H. Böttger & Liviu Ungur & Kristine Pierloot & Robert A. Schoonheydt & Bert F. Sels & Edward I. Solomon - 322-325 Metallaphotoredox-catalysed sp3–sp3 cross-coupling of carboxylic acids with alkyl halides
by Craig P. Johnston & Russell T. Smith & Simon Allmendinger & David W. C. MacMillan - 326-328 An early geodynamo driven by exsolution of mantle components from Earth’s core
by James Badro & Julien Siebert & Francis Nimmo - 329-332 Natural courtship song variation caused by an intronic retroelement in an ion channel gene
by Yun Ding & Augusto Berrocal & Tomoko Morita & Kit D. Longden & David L. Stern - 333-337 Operation of a homeostatic sleep switch
by Diogo Pimentel & Jeffrey M. Donlea & Clifford B. Talbot & Seoho M. Song & Alexander J. F. Thurston & Gero Miesenböck - 338-343 A human neurodevelopmental model for Williams syndrome
by Thanathom Chailangkarn & Cleber A. Trujillo & Beatriz C. Freitas & Branka Hrvoj-Mihic & Roberto H. Herai & Diana X. Yu & Timothy T. Brown & Maria C. Marchetto & Cedric Bardy & Lauren McHenry & Lisa Stefanacci & Anna Järvinen & Yvonne M. Searcy & Michelle DeWitt & Wenny Wong & Philip Lai & M. Colin Ard & Kari L. Hanson & Sarah Romero & Bob Jacobs & Anders M. Dale & Li Dai & Julie R. Korenberg & Fred H. Gage & Ursula Bellugi & Eric Halgren & Katerina Semendeferi & Alysson R. Muotri - 344-348 Asymmetric division of contractile domains couples cell positioning and fate specification
by Jean-Léon Maître & Hervé Turlier & Rukshala Illukkumbura & Björn Eismann & Ritsuya Niwayama & François Nédélec & Takashi Hiiragi - 349-353 HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis
by David A. Jacques & William A. McEwan & Laura Hilditch & Amanda J. Price & Greg J. Towers & Leo C. James - 354-358 Structure of mammalian respiratory complex I
by Jiapeng Zhu & Kutti R. Vinothkumar & Judy Hirst - 359-359 Correction: Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
by Yu-Hwa Huang & Chen Zhu & Yasuyuki Kondo & Ana C. Anderson & Amit Gandhi & Andrew Russell & Stephanie K. Dougan & Britt-Sabina Petersen & Espen Melum & Thomas Pertel & Kiera L. Clayton & Monika Raab & Qiang Chen & Nicole Beauchemin & Paul J. Yazaki & Michal Pyzik & Mario A. Ostrowski & Jonathan N. Glickman & Christopher E. Rudd & Hidde L. Ploegh & Andre Franke & Gregory A. Petsko & Vijay K. Kuchroo & Richard S. Blumberg - 360-360 Correction: Corrigendum: Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases
by Dominik A. Herbst & Roman P. Jakob & Franziska Zähringer & Timm Maier - 360-360 Correction: Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1
by Edward T. Chouchani & Lawrence Kazak & Mark P. Jedrychowski & Gina Z. Lu & Brian K. Erickson & John Szpyt & Kerry A. Pierce & Dina Laznik-Bogoslavski & Ramalingam Vetrivelan & Clary B. Clish & Alan J. Robinson & Steve P. Gygi & Bruce M. Spiegelman - 360-360 Correction: Corrigendum: A receptor heteromer mediates the male perception of female attractants in plants
by Tong Wang & Liang Liang & Yong Xue & Peng-Fei Jia & Wei Chen & Meng-Xia Zhang & Ying-Chun Wang & Hong-Ju Li & Wei-Cai Yang - 361-363 Let the structural symphony begin
by Stephen Ornes - 365-366 Work abroad: Visa to visit
by Barbra Rodriguez - 368-368 Legacy admissions
by S. R. Algernon
August 2016, Volume 536, Issue 7615
- 127-127 Steer driverless cars towards full automation
by John Baruch - 133-134 Hopes for revolutionary new LHC particle dashed
by Elizabeth Gibney - 134-135 Glider aims to break world record — and boost climate science
by Declan Butler - 135-135 US agency to lift ban on funding human–animal hybrids
by Sara Reardon - 136-137 Replications, ridicule and a recluse: the controversy over NgAgo gene-editing intensifies
by David Cyranoski - 137-137 Beyond CRISPR: A guide to the many other ways to edit a genome
by Heidi Ledford - 138-138 Plant and animal DNA suggests first Americans took the coastal route
by Ewen Callaway - 139-142 The bandwidth bottleneck that is throttling the Internet
by Jeff Hecht - 143-145 Biodiversity: The ravages of guns, nets and bulldozers
by Sean L. Maxwell & Richard A. Fuller & Thomas M. Brooks & James E. M. Watson - 146-147 Microbiology: Mob rule
by Adrian Woolfson - 147-147 Books in brief
by Barbara Kiser - 148-148 Kudos for female Antarctic researchers
by Jan Strugnell - 148-148 Would Mendel have won it?
by Daniel Hebenstreit - 148-148 Spot value in grant proposals
by Gabriele Bammer - 148-148 Satellite company clarifies proposal
by Doug Smith - 148-148 Reforms set to seep into India's schools
by Sanchit Misra - 150-151 Fast track for silver
by Tom Nilges - 151-152 Nanocolumns at the heart of the synapse
by Stephan J. Sigrist & Astrid G. Petzoldt - 152-154 A modern map of the human cerebral cortex
by B. T. Thomas Yeo & Simon B. Eickhoff - 154-155 Endothelial-cell killing promotes metastasis
by Claudio R. Alarcón & Sohail F. Tavazoie - 155-156 The TORC1 pathway to protein destruction
by Lynne Chantranupong & David M. Sabatini - 157-157 Fat and the fate of pancreatic tumours
by Melek Canan Arkan - 159-164 Synergistic, ultrafast mass storage and removal in artificial mixed conductors
by Chia-Chin Chen & Lijun Fu & Joachim Maier - 165-170 Tempo and mode of genome evolution in a 50,000-generation experiment
by Olivier Tenaillon & Jeffrey E. Barrick & Noah Ribeck & Daniel E. Deatherage & Jeffrey L. Blanchard & Aurko Dasgupta & Gabriel C. Wu & Sébastien Wielgoss & Stéphane Cruveiller & Claudine Médigue & Dominique Schneider & Richard E. Lenski - 171-178 A multi-modal parcellation of human cerebral cortex
by Matthew F. Glasser & Timothy S. Coalson & Emma C. Robinson & Carl D. Hacker & John Harwell & Essa Yacoub & Kamil Ugurbil & Jesper Andersson & Christian F. Beckmann & Mark Jenkinson & Stephen M. Smith & David C. Van Essen - 179-183 SAR11 bacteria linked to ocean anoxia and nitrogen loss
by Despina Tsementzi & Jieying Wu & Samuel Deutsch & Sangeeta Nath & Luis M. Rodriguez-R & Andrew S. Burns & Piyush Ranjan & Neha Sarode & Rex R. Malmstrom & Cory C. Padilla & Benjamin K. Stone & Laura A. Bristow & Morten Larsen & Jennifer B. Glass & Bo Thamdrup & Tanja Woyke & Konstantinos T. Konstantinidis & Frank J. Stewart - 184-189 An evolutionarily conserved pathway controls proteasome homeostasis
by Adrien Rousseau & Anne Bertolotti - 190-192 Heating of Jupiter’s upper atmosphere above the Great Red Spot
by J. O’Donoghue & L. Moore & T. S. Stallard & H. Melin - 193-196 A photon–photon quantum gate based on a single atom in an optical resonator
by Bastian Hacker & Stephan Welte & Gerhard Rempe & Stephan Ritter - 197-200 Single-layer MoS2 nanopores as nanopower generators
by Jiandong Feng & Michael Graf & Ke Liu & Dmitry Ovchinnikov & Dumitru Dumcenco & Mohammad Heiranian & Vishal Nandigana & Narayana R. Aluru & Andras Kis & Aleksandra Radenovic - 201-204 Abrupt plate accelerations shape rifted continental margins
by Sascha Brune & Simon E. Williams & Nathaniel P. Butterworth & R. Dietmar Müller - 205-209 Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility
by Xander Nuttle & Giuliana Giannuzzi & Michael H. Duyzend & Joshua G. Schraiber & Iñigo Narvaiza & Peter H. Sudmant & Osnat Penn & Giorgia Chiatante & Maika Malig & John Huddleston & Chris Benner & Francesca Camponeschi & Simone Ciofi-Baffoni & Holly A. F. Stessman & Maria C. N. Marchetto & Laura Denman & Lana Harshman & Carl Baker & Archana Raja & Kelsi Penewit & Nicolette Janke & W. Joyce Tang & Mario Ventura & Lucia Banci & Francesca Antonacci & Joshua M. Akey & Chris T. Amemiya & Fred H. Gage & Alexandre Reymond & Evan E. Eichler - 210-214 A trans-synaptic nanocolumn aligns neurotransmitter release to receptors
by Ai-Hui Tang & Haiwen Chen & Tuo P. Li & Sarah R. Metzbower & Harold D. MacGillavry & Thomas A. Blanpied - 215-218 Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
by Boris Strilic & Lida Yang & Julián Albarrán-Juárez & Laurens Wachsmuth & Kang Han & Ulrike C. Müller & Manolis Pasparakis & Stefan Offermanns - 219-223 Global profiling of SRP interaction with nascent polypeptides
by Daniela Schibich & Felix Gloge & Ina Pöhner & Patrik Björkholm & Rebecca C. Wade & Gunnar von Heijne & Bernd Bukau & Günter Kramer - 224-228 Cotranslational signal-independent SRP preloading during membrane targeting
by Justin W. Chartron & Katherine C. L. Hunt & Judith Frydman - 229-233 Mechanism of arginine sensing by CASTOR1 upstream of mTORC1
by Robert A. Saxton & Lynne Chantranupong & Kevin E. Knockenhauer & Thomas U. Schwartz & David M. Sabatini - 234-237 Reconstruction of bacterial transcription-coupled repair at single-molecule resolution
by Jun Fan & Mathieu Leroux-Coyau & Nigel J. Savery & Terence R. Strick - 238-238 Erratum: Universal resilience patterns in complex networks
by Jianxi Gao & Baruch Barzel & Albert-László Barabási - 238-238 Erratum: Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
by Minoru Takasato & Pei X. Er & Han S. Chiu & Barbara Maier & Gregory J. Baillie & Charles Ferguson & Robert G. Parton & Ernst J. Wolvetang & Matthias S. Roost & Susana M. Chuva de Sousa Lopes & Melissa H. Little - 238-238 Correction: Corrigendum: Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
by Benoit Chassaing & Omry Koren & Julia K. Goodrich & Angela C. Poole & Shanthi Srinivasan & Ruth E. Ley & Andrew T. Gewirtz - 239-241 Research protocols: A forest of hypotheses
by Julia Rosen - 241-241 Turning point: Planet navigator
by Smriti Mallapaty - 244-244 Walls of Nigeria
by Jeremy Szal
August 2016, Volume 536, Issue 7614
- 7-7 Donald Trump’s appeal should be a call to arms
by Daniel Sarewitz - 13-14 Troubled Japanese space agency seeks fresh start
by Alexandra Witze - 14-15 Monumental proof to torment mathematicians for years to come
by Davide Castelvecchi - 15-16 Scientists seek influence on ‘Brexit ministry’
by Elizabeth Gibney - 16-17 Legal confusion threatens to slow data science
by Simon Oxenham - 18-19 Scholarly Olympics: How the games have shaped research
by Daniel Cressey & Ramin Skibba & Richard Van Noorden - 20-22 Welcome to the Cyborg Olympics
by Sara Reardon - 23-25 Take responsibility for electronic-waste disposal
by Zhaohua Wang & Bin Zhang & Dabo Guan - 26-27 Economics: Singular currency
by Jonathan Portes - 27-28 Child development: A cognitive case for un‑parenting
by Josie Glausiusz - 28-29 China: A hydrological history
by Andrea Janku - 30-30 Refereed science to guide action on EDCs
by Leonardo Trasande - 30-30 Mentoring female scientists in Africa
by Rose G. F. Leke & S. Kwedi Nolna - 30-30 China: Standardize R&D costing
by Yutao Sun & Cong Cao - 30-30 China: Change tack to boost basic research
by Raphael K. Didham & Chao-Dong Zhu - 32-33 Death-defying plaque cells
by Ira Tabas - 33-34 Bacteria synchronized for drug delivery
by Shibin Zhou - 35-36 A milestone in quantum computing
by Stephen D. Bartlett - 36-37 Protection for anaesthetized mice
by Laura Cornelissen & Charles Berde - 37-38 Still a geneticist's nightmare
by Stephen S. Rich - 38-39 Destruction of discrete charge
by Yuli V. Nazarov - 41-47 The genetic architecture of type 2 diabetes
by Christian Fuchsberger & Jason Flannick & Tanya M. Teslovich & Anubha Mahajan & Vineeta Agarwala & Kyle J. Gaulton & Clement Ma & Pierre Fontanillas & Loukas Moutsianas & Davis J. McCarthy & Manuel A. Rivas & John R. B. Perry & Xueling Sim & Thomas W. Blackwell & Neil R. Robertson & N. William Rayner & Pablo Cingolani & Adam E. Locke & Juan Fernandez Tajes & Heather M. Highland & Josee Dupuis & Peter S. Chines & Cecilia M. Lindgren & Christopher Hartl & Anne U. Jackson & Han Chen & Jeroen R. Huyghe & Martijn van de Bunt & Richard D. Pearson & Ashish Kumar & Martina Müller-Nurasyid & Niels Grarup & Heather M. Stringham & Eric R. Gamazon & Jaehoon Lee & Yuhui Chen & Robert A. Scott & Jennifer E. Below & Peng Chen & Jinyan Huang & Min Jin Go & Michael L. Stitzel & Dorota Pasko & Stephen C. J. Parker & Tibor V. Varga & Todd Green & Nicola L. Beer & Aaron G. Day-Williams & Teresa Ferreira & Tasha Fingerlin & Momoko Horikoshi & Cheng Hu & Iksoo Huh & Mohammad Kamran Ikram & Bong-Jo Kim & Yongkang Kim & Young Jin Kim & Min-Seok Kwon & Juyoung Lee & Selyeong Lee & Keng-Han Lin & Taylor J. Maxwell & Yoshihiko Nagai & Xu Wang & Ryan P. Welch & Joon Yoon & Weihua Zhang & Nir Barzilai & Benjamin F. Voight & Bok-Ghee Han & Christopher P. Jenkinson & Teemu Kuulasmaa & Johanna Kuusisto & Alisa Manning & Maggie C. Y. Ng & Nicholette D. Palmer & Beverley Balkau & Alena Stančáková & Hanna E. Abboud & Heiner Boeing & Vilmantas Giedraitis & Dorairaj Prabhakaran & Omri Gottesman & James Scott & Jason Carey & Phoenix Kwan & George Grant & Joshua D. Smith & Benjamin M. Neale & Shaun Purcell & Adam S. Butterworth & Joanna M. M. Howson & Heung Man Lee & Yingchang Lu & Soo-Heon Kwak & Wei Zhao & John Danesh & Vincent K. L. Lam & Kyong Soo Park & Danish Saleheen & Wing Yee So & Claudia H. T. Tam & Uzma Afzal & David Aguilar & Rector Arya & Tin Aung & Edmund Chan & Carmen Navarro & Ching-Yu Cheng & Domenico Palli & Adolfo Correa & Joanne E. Curran & Denis Rybin & Vidya S. Farook & Sharon P. Fowler & Barry I. Freedman & Michael Griswold & Daniel Esten Hale & Pamela J. Hicks & Chiea-Chuen Khor & Satish Kumar & Benjamin Lehne & Dorothée Thuillier & Wei Yen Lim & Jianjun Liu & Yvonne T. van der Schouw & Marie Loh & Solomon K. Musani & Sobha Puppala & William R. Scott & Loïc Yengo & Sian-Tsung Tan & Herman A. Taylor Jr. & Farook Thameem & Gregory Wilson & Tien Yin Wong & Pål Rasmus Njølstad & Jonathan C. Levy & Massimo Mangino & Lori L. Bonnycastle & Thomas Schwarzmayr & João Fadista & Gabriela L. Surdulescu & Christian Herder & Christopher J. Groves & Thomas Wieland & Jette Bork-Jensen & Ivan Brandslund & Cramer Christensen & Heikki A. Koistinen & Alex S. F. Doney & Leena Kinnunen & Tõnu Esko & Andrew J. Farmer & Liisa Hakaste & Dylan Hodgkiss & Jasmina Kravic & Valeriya Lyssenko & Mette Hollensted & Marit E. Jørgensen & Torben Jørgensen & Claes Ladenvall & Johanne Marie Justesen & Annemari Käräjämäki & Jennifer Kriebel & Wolfgang Rathmann & Lars Lannfelt & Torsten Lauritzen & Narisu Narisu & Allan Linneberg & Olle Melander & Lili Milani & Matt Neville & Marju Orho-Melander & Lu Qi & Qibin Qi & Michael Roden & Olov Rolandsson & Amy Swift & Anders H. Rosengren & Kathleen Stirrups & Andrew R. Wood & Evelin Mihailov & Christine Blancher & Mauricio O. Carneiro & Jared Maguire & Ryan Poplin & Khalid Shakir & Timothy Fennell & Mark DePristo & Martin Hrabé de Angelis & Panos Deloukas & Anette P. Gjesing & Goo Jun & Peter Nilsson & Jacquelyn Murphy & Robert Onofrio & Barbara Thorand & Torben Hansen & Christa Meisinger & Frank B. Hu & Bo Isomaa & Fredrik Karpe & Liming Liang & Annette Peters & Cornelia Huth & Stephen P. O’Rahilly & Colin N. A. Palmer & Oluf Pedersen & Rainer Rauramaa & Jaakko Tuomilehto & Veikko Salomaa & Richard M. Watanabe & Ann-Christine Syvänen & Richard N. Bergman & Dwaipayan Bharadwaj & Erwin P. Bottinger & Yoon Shin Cho & Giriraj R. Chandak & Juliana C. N. Chan & Kee Seng Chia & Mark J. Daly & Shah B. Ebrahim & Claudia Langenberg & Paul Elliott & Kathleen A. Jablonski & Donna M. Lehman & Weiping Jia & Ronald C. W. Ma & Toni I. Pollin & Manjinder Sandhu & Nikhil Tandon & Philippe Froguel & Inês Barroso & Yik Ying Teo & Eleftheria Zeggini & Ruth J. F. Loos & Kerrin S. Small & Janina S. Ried & Ralph A. DeFronzo & Harald Grallert & Benjamin Glaser & Andres Metspalu & Nicholas J. Wareham & Mark Walker & Eric Banks & Christian Gieger & Erik Ingelsson & Hae Kyung Im & Thomas Illig & Paul W. Franks & Gemma Buck & Joseph Trakalo & David Buck & Inga Prokopenko & Reedik Mägi & Lars Lind & Yossi Farjoun & Katharine R. Owen & Anna L. Gloyn & Konstantin Strauch & Tiinamaija Tuomi & Jaspal Singh Kooner & Jong-Young Lee & Taesung Park & Peter Donnelly & Andrew D. Morris & Andrew T. Hattersley & Donald W. Bowden & Francis S. Collins & Gil Atzmon & John C. Chambers & Timothy D. Spector & Markku Laakso & Tim M. Strom & Graeme I. Bell & John Blangero & Ravindranath Duggirala & E. Shyong Tai & Gilean McVean & Craig L. Hanis & James G. Wilson & Mark Seielstad & Timothy M. Frayling & James B. Meigs & Nancy J. Cox & Rob Sladek & Eric S. Lander & Stacey Gabriel & Noël P. Burtt & Karen L. Mohlke & Thomas Meitinger & Leif Groop & Goncalo Abecasis & Jose C. Florez & Laura J. Scott & Andrew P. Morris & Hyun Min Kang & Michael Boehnke & David Altshuler & Mark I. McCarthy - 48-53 Structural basis of potent Zika–dengue virus antibody cross-neutralization
by Giovanna Barba-Spaeth & Wanwisa Dejnirattisai & Alexander Rouvinski & Marie-Christine Vaney & Iris Medits & Arvind Sharma & Etienne Simon-Lorière & Anavaj Sakuntabhai & Van-Mai Cao-Lormeau & Ahmed Haouz & Patrick England & Karin Stiasny & Juthathip Mongkolsapaya & Franz X. Heinz & Gavin R. Screaton & Félix A. Rey - 54-57 Bright carbonate deposits as evidence of aqueous alteration on (1) Ceres
by M. C. De Sanctis & A. Raponi & E. Ammannito & M. Ciarniello & M. J. Toplis & H. Y. McSween & J. C. Castillo-Rogez & B. L. Ehlmann & F. G. Carrozzo & S. Marchi & F. Tosi & F. Zambon & F. Capaccioni & M. T. Capria & S. Fonte & M. Formisano & A. Frigeri & M. Giardino & A. Longobardo & G. Magni & E. Palomba & L. A. McFadden & C. M. Pieters & R. Jaumann & P. Schenk & R. Mugnuolo & C. A. Raymond & C. T. Russell - 58-62 Controlling charge quantization with quantum fluctuations
by S. Jezouin & Z. Iftikhar & A. Anthore & F. D. Parmentier & U. Gennser & A. Cavanna & A. Ouerghi & I. P. Levkivskyi & E. Idrisov & E. V. Sukhorukov & L. I. Glazman & F. Pierre - 63-66 Demonstration of a small programmable quantum computer with atomic qubits
by S. Debnath & N. M. Linke & C. Figgatt & K. A. Landsman & K. Wright & C. Monroe - 67-71 Carbon-based tribofilms from lubricating oils
by Ali Erdemir & Giovanni Ramirez & Osman L. Eryilmaz & Badri Narayanan & Yifeng Liao & Ganesh Kamath & Subramanian K. R. S. Sankaranarayanan - 72-75 Evidence for climate change in the satellite cloud record
by Joel R. Norris & Robert J. Allen & Amato T. Evan & Mark D. Zelinka & Christopher W. O’Dell & Stephen A. Klein - 76-80 A novel excitatory network for the control of breathing
by Tatiana M. Anderson & Alfredo J. Garcia & Nathan A. Baertsch & Julia Pollak & Jacob C. Bloom & Aguan D. Wei & Karan G. Rai & Jan-Marino Ramirez - 81-85 Synchronized cycles of bacterial lysis for in vivo delivery
by M. Omar Din & Tal Danino & Arthur Prindle & Matt Skalak & Jangir Selimkhanov & Kaitlin Allen & Ellixis Julio & Eta Atolia & Lev S. Tsimring & Sangeeta N. Bhatia & Jeff Hasty - 86-90 CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis
by Yoko Kojima & Jens-Peter Volkmer & Kelly McKenna & Mete Civelek & Aldons Jake Lusis & Clint L. Miller & Daniel Direnzo & Vivek Nanda & Jianqin Ye & Andrew J. Connolly & Eric E. Schadt & Thomas Quertermous & Paola Betancur & Lars Maegdefessel & Ljubica Perisic Matic & Ulf Hedin & Irving L. Weissman & Nicholas J. Leeper - 91-95 Neoantigen landscape dynamics during human melanoma–T cell interactions
by Els M. E. Verdegaal & Noel F. C. C. de Miranda & Marten Visser & Tom Harryvan & Marit M. van Buuren & Rikke S. Andersen & Sine R. Hadrup & Caroline E. van der Minne & Remko Schotte & Hergen Spits & John B. A. G. Haanen & Ellen H. W. Kapiteijn & Ton N. Schumacher & Sjoerd H. van der Burg - 96-99 eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
by Amy S. Y. Lee & Philip J. Kranzusch & Jennifer A. Doudna & Jamie H. D. Cate - 100-103 The structural basis of modified nucleosome recognition by 53BP1
by Marcus D. Wilson & Samir Benlekbir & Amélie Fradet-Turcotte & Alana Sherker & Jean-Philippe Julien & Andrea McEwan & Sylvie M. Noordermeer & Frank Sicheri & John L. Rubinstein & Daniel Durocher - 104-107 Structure of the adenosine A2A receptor bound to an engineered G protein
by Byron Carpenter & Rony Nehmé & Tony Warne & Andrew G. W. Leslie & Christopher G. Tate - 108-111 Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM
by Yan Zhao & Shanshuang Chen & Craig Yoshioka & Isabelle Baconguis & Eric Gouaux - 112-112 Correction: Corrigendum: Structure of promoter-bound TFIID and model of human pre-initiation complex assembly
by Robert K. Louder & Yuan He & José Ramón López-Blanco & Jie Fang & Pablo Chacón & Eva Nogales - 112-112 Retraction Note: Effects of electron correlations on transport properties of iron at Earth’s core conditions
by Peng Zhang & R. E. Cohen & K. Haule - 112-112 Correction: Corrigendum: Flexible high-temperature dielectric materials from polymer nanocomposites
by Qi Li & Lei Chen & Matthew R. Gadinski & Shihai Zhang & Guangzu Zhang & Haoyu U. Li & Elissei Iagodkine & Aman Haque & Long-Qing Chen & Thomas N. Jackson & Qing Wang - 113-114 ‘Kudos’ promises to help scientists promote their papers to new audiences
by Jeffrey Perkel - 115-117 Conference presentations: Lead the poster parade
by Chris Woolston - 117-117 Turning point: Kevin Esvelt
by Vijee Venkatraman - 120-120 Floating in my tin can
by Gerri Leen
July 2016, Volume 535, Issue 7613
- 49-49 Rising stars
by Nicky Phillips - 50-51 The new contenders
by Larissa Kogleck - 467-467 Resilient British science will withstand Brexit
by Ehsan Masood - 473-474 Trump vs Clinton: worlds apart on science
by Jeff Tollefson - 474-474 Planet hunters seek new ways to detect alien life
by Alexandra Witze - 475-476 Brazil asks whether Zika acts alone to cause birth defects
by Declan Butler - 476-477 Chinese scientists to pioneer first human CRISPR trial
by David Cyranoski - 477-478 Europe’s premier funding agency measures its impact
by Alison Abbott - 478-479 Chinese satellite is one giant step for the quantum internet
by Elizabeth Gibney - 480-483 180,000 forgotten photos reveal the future of Greenland’s ice
by Quirin Schiermeier - 484-486 Tapping genetics for better beer
by Ewen Callaway - 490-491 Science fiction: The science that fed Frankenstein
by Richard Holmes - 491-491 Books in brief
by Barbara Kiser - 493-493 diseases that neglect no goals
by Christopher Fitzpatrick & Mathieu Bangert & Dirk Engels - 493-493 A very preventable mammal extinction
by John C. Z. Woinarski - 493-493 Fresh strategies to save orangutans
by Andrew J. Marshall & Serge Wich & Marc Ancrenaz - 493-493 create a coordinating body
by Peter M. Haas - 493-493 Vet reproducibility of biology preprints
by Roy Calne - 496-497 Amazon music
by Robert Zatorre - 497-498 Unexpected fix for ocean models
by Kathryn A. Kelly & LuAnne Thompson - 498-500 Mitochondrial DNA in evolution and disease
by Douglas C. Wallace - 500-501 Dynamo theory questioned
by Paul Charbonneau - 501-502 Antibiotics right under our nose
by Kim Lewis & Philip Strandwitz - 502-503 Thirty-five years of endless cell potential
by M. Azim Surani - 505-510 Rapid signalling in distinct dopaminergic axons during locomotion and reward
by M. W. Howe & D. A. Dombeck - 511-516 Human commensals producing a novel antibiotic impair pathogen colonization
by Alexander Zipperer & Martin C. Konnerth & Claudia Laux & Anne Berscheid & Daniela Janek & Christopher Weidenmaier & Marc Burian & Nadine A. Schilling & Christoph Slavetinsky & Matthias Marschal & Matthias Willmann & Hubert Kalbacher & Birgit Schittek & Heike Brötz-Oesterhelt & Stephanie Grond & Andreas Peschel & Bernhard Krismer - 517-522 Structural basis of Smoothened regulation by its extracellular domains
by Eamon F. X. Byrne & Ria Sircar & Paul S. Miller & George Hedger & Giovanni Luchetti & Sigrid Nachtergaele & Mark D. Tully & Laurel Mydock-McGrane & Douglas F. Covey & Robert P. Rambo & Mark S. P. Sansom & Simon Newstead & Rajat Rohatgi & Christian Siebold