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Content
May 2016, Volume 533, Issue 7603
- 333-337 Reproducible pharmacogenomic profiling of cancer cell line panels
by Peter M. Haverty & Eva Lin & Jenille Tan & Yihong Yu & Billy Lam & Steve Lianoglou & Richard M. Neve & Scott Martin & Jeff Settleman & Robert L. Yauch & Richard Bourgon - 338-345 A platform for the discovery of new macrolide antibiotics
by Ian B. Seiple & Ziyang Zhang & Pavol Jakubec & Audrey Langlois-Mercier & Peter M. Wright & Daniel T. Hog & Kazuo Yabu & Senkara Rao Allu & Takehiro Fukuzaki & Peter N. Carlsen & Yoshiaki Kitamura & Xiang Zhou & Matthew L. Condakes & Filip T. Szczypiński & William D. Green & Andrew G. Myers - 346-352 Structure of the T4 baseplate and its function in triggering sheath contraction
by Nicholas M. I. Taylor & Nikolai S. Prokhorov & Ricardo C. Guerrero-Ferreira & Mikhail M. Shneider & Christopher Browning & Kenneth N. Goldie & Henning Stahlberg & Petr G. Leiman - 353-358 Transcription initiation complex structures elucidate DNA opening
by C. Plaschka & M. Hantsche & C. Dienemann & C. Burzinski & J. Plitzko & P. Cramer - 359-365 Near-atomic resolution visualization of human transcription promoter opening
by Yuan He & Chunli Yan & Jie Fang & Carla Inouye & Robert Tjian & Ivaylo Ivanov & Eva Nogales - 366-368 An irradiated brown-dwarf companion to an accreting white dwarf
by Juan V. Hernández Santisteban & Christian Knigge & Stuart P. Littlefair & Rene P. Breton & Vikram S. Dhillon & Boris T. Gänsicke & Thomas R. Marsh & Magaretha L. Pretorius & John Southworth & Peter H. Hauschildt - 369-373 Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals
by Yuta Suzuki & Giovanni Cardone & David Restrepo & Pablo D. Zavattieri & Timothy S. Baker & F. Akif Tezcan - 374-379 Iron(III)-catalysed carbonyl–olefin metathesis
by Jacob R. Ludwig & Paul M. Zimmerman & Joseph B. Gianino & Corinna S. Schindler - 380-384 Changing atmospheric CO2 concentration was the primary driver of early Cenozoic climate
by Eleni Anagnostou & Eleanor H. John & Kirsty M. Edgar & Gavin L. Foster & Andy Ridgwell & Gordon N. Inglis & Richard D. Pancost & Daniel J. Lunt & Paul N. Pearson - 385-389 Repeated large-scale retreat and advance of Totten Glacier indicated by inland bed erosion
by A. R. A. Aitken & J. L. Roberts & T. D. van Ommen & D. A. Young & N. R. Golledge & J. S. Greenbaum & D. D. Blankenship & M. J. Siegert - 390-392 Metabolic acceleration and the evolution of human brain size and life history
by Herman Pontzer & Mary H. Brown & David A. Raichlen & Holly Dunsworth & Brian Hare & Kara Walker & Amy Luke & Lara R. Dugas & Ramon Durazo-Arvizu & Dale Schoeller & Jacob Plange-Rhule & Pascal Bovet & Terrence E. Forrester & Estelle V. Lambert & Melissa Emery Thompson & Robert W. Shumaker & Stephen R. Ross - 393-396 Deep-sea diversity patterns are shaped by energy availability
by Skipton N. C. Woolley & Derek P. Tittensor & Piers K. Dunstan & Gurutzeta Guillera-Arroita & José J. Lahoz-Monfort & Brendan A. Wintle & Boris Worm & Timothy D. O’Hara - 397-401 Local fitness landscape of the green fluorescent protein
by Karen S. Sarkisyan & Dmitry A. Bolotin & Margarita V. Meer & Dinara R. Usmanova & Alexander S. Mishin & George V. Sharonov & Dmitry N. Ivankov & Nina G. Bozhanova & Mikhail S. Baranov & Onuralp Soylemez & Natalya S. Bogatyreva & Peter K. Vlasov & Evgeny S. Egorov & Maria D. Logacheva & Alexey S. Kondrashov & Dmitry M. Chudakov & Ekaterina V. Putintseva & Ilgar Z. Mamedov & Dan S. Tawfik & Konstantin A. Lukyanov & Fyodor A. Kondrashov - 402-406 Opponent and bidirectional control of movement velocity in the basal ganglia
by Eric A. Yttri & Joshua T. Dudman - 407-410 FGF8 and SHH substitute for anterior–posterior tissue interactions to induce limb regeneration
by Eugeniu Nacu & Elena Gromberg & Catarina R. Oliveira & David Drechsel & Elly M. Tanaka - 411-415 An obligatory role for neurotensin in high-fat-diet-induced obesity
by Jing Li & Jun Song & Yekaterina Y. Zaytseva & Yajuan Liu & Piotr Rychahou & Kai Jiang & Marlene E. Starr & Ji Tae Kim & Jennifer W. Harris & Frederique B. Yiannikouris & Wendy S. Katz & Peter M. Nilsson & Marju Orho-Melander & Jing Chen & Haining Zhu & Timothy Fahrenholz & Richard M. Higashi & Tianyan Gao & Andrew J. Morris & Lisa A. Cassis & Teresa W. -M. Fan & Heidi L. Weiss & Paul R. Dobner & Olle Melander & Jianhang Jia & B. Mark Evers - 416-419 Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response
by Yi-Fan Lin & Anna M. Schulz & Mark W. Pellegrino & Yun Lu & Shai Shaham & Cole M. Haynes - 420-424 Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
by Alexis C. Komor & Yongjoo B. Kim & Michael S. Packer & John A. Zuris & David R. Liu - 425-428 Structure of the thermally stable Zika virus
by Victor A. Kostyuchenko & Elisa X. Y. Lim & Shuijun Zhang & Guntur Fibriansah & Thiam-Seng Ng & Justin S. G. Ooi & Jian Shi & Shee-Mei Lok - 429-430 Relationships: Doctor's advice
by Alaina Levine - 430-430 Trade talk: Cell negotiator
by Monya Baker - 432-432 Project Earth is leaving beta
by J.W. Alden
May 2016, Volume 533, Issue 7602
- 53-53 Open innovation
by Richard Hodson - 54-55 A new chapter in innovation
by David Holmes - 56-58 Competition: Unlikely partnerships
by Neil Savage - 59-59 Q&A: Bernard Munos
by Eric Bender - 60-61 Chemical probes: A shared toolbox
by Andrew R. Scott - 62-64 Challenges: Crowdsourced solutions
by Eric Bender - 65-67 Compound screening: Fresh hunting ground
by Annabel McGilvray - 68-69 Tropical disease: A neglected cause
by Lucas Laursen - 70-70 Perspective: Science is still too closed
by Aled Edwards - 71-72 Data sharing: Access all areas
by Brian Owens - 147-147 The pressure to publish pushes down quality
by Daniel Sarewitz - 149-149 Higgs Bison or Niels Bohrson? Twitter offers names for Fermilab’s baby bison
by Chris Woolston - 153-154 Low-cost headsets boost virtual reality’s lab appeal
by Davide Castelvecchi - 154-155 Gene variants linked to success at school prove divisive
by Erika Check Hayden - 155-155 Intricate animal and flower tattoos found on Egyptian mummy
by Traci Watson - 156-157 Biologists struggle with push to eliminate radioactive caesium in labs
by Jeff Tollefson - 157-158 France’s research minister lays out his priorities
by Declan Butler - 158-159 Row over proposed Italian biomedical centre intensifies
by Alison Abbott - 160-163 The spectrum of sex development: Eric Vilain and the intersex controversy
by Sara Reardon - 164-167 How to hack the hackers: The human side of cybercrime
by M. Mitchell Waldrop - 169-171 Embryology policy: Revisit the 14-day rule
by Insoo Hyun & Amy Wilkerson & Josephine Johnston - 172-174 Natural history: Restore our sense of species
by Klaas-Douwe B. Dijkstra - 175-176 History: A chemist's contradictions
by Mark Peplow - 176-177 Biodiversity: England's green and well-known land
by Stuart Pimm - 178-178 Genetics: On the heredity trail
by Matthew Cobb - 179-179 El Niño dons winter disguise as La Niña
by Judah Cohen - 179-179 Reminder to deposit DNA sequences
by Steven L. Salzberg - 179-179 Reform oversight of Italy's science funds
by Ernesto Carafoli & Cesare Montecucco - 179-179 Regulate devices for brain stimulation
by Olivia Carter & Jason Forte - 182-183 Implantation barrier overcome
by Janet Rossant - 183-184 Precision pruning of molecules
by Kin S. Yang & Keary M. Engle - 184-186 Ancient air caught by shooting stars
by Kevin Zahnle & Roger Buick - 186-187 Quasiparticles on a collision course
by Dirk van der Marel - 187-188 Fresh solutions to the four-body problem
by Douglas P. Hamilton - 188-189 Wired for sex
by Douglas S. Portman - 191-199 Palaeoclimatic insights into forcing and response of monsoon rainfall
by Mahyar Mohtadi & Matthias Prange & Stephan Steinke - 200-205 The Atlantic salmon genome provides insights into rediploidization
by Sigbjørn Lien & Ben F. Koop & Simen R. Sandve & Jason R. Miller & Matthew P. Kent & Torfinn Nome & Torgeir R. Hvidsten & Jong S. Leong & David R. Minkley & Aleksey Zimin & Fabian Grammes & Harald Grove & Arne Gjuvsland & Brian Walenz & Russell A. Hermansen & Kris von Schalburg & Eric B. Rondeau & Alex Di Genova & Jeevan K. A. Samy & Jon Olav Vik & Magnus D. Vigeland & Lis Caler & Unni Grimholt & Sissel Jentoft & Dag Inge Våge & Pieter de Jong & Thomas Moen & Matthew Baranski & Yniv Palti & Douglas R. Smith & James A. Yorke & Alexander J. Nederbragt & Ave Tooming-Klunderud & Kjetill S. Jakobsen & Xuanting Jiang & Dingding Fan & Yan Hu & David A. Liberles & Rodrigo Vidal & Patricia Iturra & Steven J. M. Jones & Inge Jonassen & Alejandro Maass & Stig W. Omholt & William S. Davidson - 206-211 Sex-specific pruning of neuronal synapses in Caenorhabditis elegans
by Meital Oren-Suissa & Emily A. Bayer & Oliver Hobert - 212-216 Interconnected microbiomes and resistomes in low-income human habitats
by Erica C. Pehrsson & Pablo Tsukayama & Sanket Patel & Melissa Mejía-Bautista & Giordano Sosa-Soto & Karla M. Navarrete & Maritza Calderon & Lilia Cabrera & William Hoyos-Arango & M. Teresita Bertoli & Douglas E. Berg & Robert H. Gilman & Gautam Dantas - 217-220 No Sun-like dynamo on the active star ζ Andromedae from starspot asymmetry
by R. M. Roettenbacher & J. D. Monnier & H. Korhonen & A. N. Aarnio & F. Baron & X. Che & R. O. Harmon & Zs. Kővári & S. Kraus & G. H. Schaefer & G. Torres & M. Zhao & T. A. ten Brummelaar & J. Sturmann & L. Sturmann - 221-224 Temperate Earth-sized planets transiting a nearby ultracool dwarf star
by Michaël Gillon & Emmanuël Jehin & Susan M. Lederer & Laetitia Delrez & Julien de Wit & Artem Burdanov & Valérie Van Grootel & Adam J. Burgasser & Amaury H. M. J. Triaud & Cyrielle Opitom & Brice-Olivier Demory & Devendra K. Sahu & Daniella Bardalez Gagliuffi & Pierre Magain & Didier Queloz - 225-229 Lightwave-driven quasiparticle collisions on a subcycle timescale
by F. Langer & M. Hohenleutner & C. P. Schmid & C. Poellmann & P. Nagler & T. Korn & C. Schüller & M. S. Sherwin & U. Huttner & J. T. Steiner & S. W. Koch & M. Kira & R. Huber - 230-234 Site-selective and stereoselective functionalization of unactivated C–H bonds
by Kuangbiao Liao & Solymar Negretti & Djamaladdin G. Musaev & John Bacsa & Huw M. L. Davies - 235-238 Ancient micrometeorites suggestive of an oxygen-rich Archaean upper atmosphere
by Andrew G. Tomkins & Lara Bowlt & Matthew Genge & Sasha Wilson & Helen E. A. Brand & Jeremy L. Wykes - 239-242 A rapid burst in hotspot motion through the interaction of tectonics and deep mantle flow
by Rakib Hassan & R. Dietmar Müller & Michael Gurnis & Simon E. Williams & Nicolas Flament - 243-246 First North American fossil monkey and early Miocene tropical biotic interchange
by Jonathan I. Bloch & Emily D. Woodruff & Aaron R. Wood & Aldo F. Rincon & Arianna R. Harrington & Gary S. Morgan & David A. Foster & Camilo Montes & Carlos A. Jaramillo & Nathan A. Jud & Douglas S. Jones & Bruce J. MacFadden - 247-250 Restoring cortical control of functional movement in a human with quadriplegia
by Chad E. Bouton & Ammar Shaikhouni & Nicholas V. Annetta & Marcia A. Bockbrader & David A. Friedenberg & Dylan M. Nielson & Gaurav Sharma & Per B. Sederberg & Bradley C. Glenn & W. Jerry Mysiw & Austin G. Morgan & Milind Deogaonkar & Ali R. Rezai - 251-254 Self-organization of the in vitro attached human embryo
by Alessia Deglincerti & Gist F. Croft & Lauren N. Pietila & Magdalena Zernicka-Goetz & Eric D. Siggia & Ali H. Brivanlou - 255-259 The evolution of cooperation within the gut microbiota
by Seth Rakoff-Nahoum & Kevin R. Foster & Laurie E. Comstock - 260-264 Molecular mechanism of APC/C activation by mitotic phosphorylation
by Suyang Zhang & Leifu Chang & Claudio Alfieri & Ziguo Zhang & Jing Yang & Sarah Maslen & Mark Skehel & David Barford - 265-268 Activation of the A2A adenosine G-protein-coupled receptor by conformational selection
by Libin Ye & Ned Van Eps & Marco Zimmer & Oliver P. Ernst & R. Scott Prosser - 269-273 Architecture of the mitochondrial calcium uniporter
by Kirill Oxenoid & Ying Dong & Chan Cao & Tanxing Cui & Yasemin Sancak & Andrew L. Markhard & Zenon Grabarek & Liangliang Kong & Zhijun Liu & Bo Ouyang & Yao Cong & Vamsi K. Mootha & James J. Chou - 274-277 Extra-helical binding site of a glucagon receptor antagonist
by Ali Jazayeri & Andrew S. Doré & Daniel Lamb & Harini Krishnamurthy & Stacey M. Southall & Asma H. Baig & Andrea Bortolato & Markus Koglin & Nathan J. Robertson & James C. Errey & Stephen P. Andrews & Iryna Teobald & Alastair J. H. Brown & Robert M. Cooke & Malcolm Weir & Fiona H. Marshall - 278-278 Correction: Corrigendum: Structural and functional features of central nervous system lymphatic vessels
by Antoine Louveau & Igor Smirnov & Timothy J. Keyes & Jacob D. Eccles & Sherin J. Rouhani & J. David Peske & Noel C. Derecki & David Castle & James W. Mandell & Kevin S. Lee & Tajie H. Harris & Jonathan Kipnis - 278-278 Correction: Corrigendum: Bees prefer foods containing neonicotinoid pesticides
by Sébastien C. Kessler & Erin Jo Tiedeken & Kerry L. Simcock & Sophie Derveau & Jessica Mitchell & Samantha Softley & Amy Radcliffe & Jane C. Stout & Geraldine A. Wright - 278-278 Correction: Corrigendum: Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis
by Shidong Jia & Zhenning Liu & Sen Zhang & Pixu Liu & Lei Zhang & Sang Hyun Lee & Jing Zhang & Sabina Signoretti & Massimo Loda & Thomas M. Roberts & Jean J. Zhao - 279-281 Peer review: Close inspection
by Quirin Schiermeier - 281-281 Turning point: Intelligence programmer
by Virginia Gewin - 284-284 Venice, Version 9.0
by Preston Grassmann
May 2016, Volume 533, Issue 7601
- 5-5 Research commercialization
by Herb Brody - 6-7 Cashing in on science
by Alla Katsnelson - 9-9 Set up a public registry of competing interests
by Adam G. Dunn - 10-12 Start-ups: A sense of enterprise
by Neil Savage - 13-15 Technology transfer: The leap to industry
by Jessica Wapner - 15-16 Human embryos grown in lab for longer than ever before
by Sara Reardon - 16-17 Australia softens blow of climate job cuts
by Myles Gough - 18-19 Software error doomed Japanese Hitomi spacecraft
by Alexandra Witze - 19-19 US and China eye up European gravitational-wave mission
by Elizabeth Gibney - 20-21 Assessment: Academic return
by Michael Eisenstein - 20-21 Stem-cell plan aims to bring rhino back from brink of extinction
by Ewen Callaway - 22-23 Australia: Engagement upgrade
by Bianca Nogrady - 22-25 Can artificial intelligence create the next wonder material?
by Nicola Nosengo - 26-28 Nine years of censorship
by Lesley Evans Ogden - 29-31 Policy: Security spending must cover disease outbreaks
by Tadataka Yamada & V. Ayano Ogawa & Maria Freire - 30-31 Q&A: Horst Domdey
by Chelsea Wald - 32-33 China: Building an innovator
by Nicky Phillips - 32-33 Ethology: Intrepid translator of the hive
by Mark L. Winston - 33-33 Books in brief
by Barbara Kiser - 34-34 Physics: Material to meaning
by Robert P. Crease - 36-36 Curb anchor scour for green shipping
by Andrew R. Davis & Allison Broad - 36-36 Debate over whale longevity is futile
by P. J. Nico de Bruyn - 36-36 Shared goals score reproducible results
by Eric Buenz - 36-36 Renewables targeted before Fukushima
by Aleh Cherp & Jessica Jewell - 38-39 Clockwork at the atomic scale
by Marjana Ležaić - 39-40 Evolved to overcome Bt-toxin resistance
by Daniel Dovrat & Amir Aharoni - 40-41 Guilt by genetic association
by Asa Abeliovich & Herve Rhinn - 40-42 Collaboration: The geography of discovery
by Emily Sohn - 42-43 Mum's microbes boost baby's immunity
by Mihir Pendse & Lora V. Hooper - 43-44 Ubiquitination without E1 and E2 enzymes
by Sagar Bhogaraju & Ivan Dikic - 43-45 Funding: Donor drugs
by Cassandra Willyard - 44-45 Elusive transition spotted in thorium
by Marianna Safronova - 47-47 Q&A: Helga Nowotny
by Chelsea Wald - 47-51 Direct detection of the 229Th nuclear clock transition
by Lars von der Wense & Benedict Seiferle & Mustapha Laatiaoui & Jürgen B. Neumayr & Hans-Jörg Maier & Hans-Friedrich Wirth & Christoph Mokry & Jörg Runke & Klaus Eberhardt & Christoph E. Düllmann & Norbert G. Trautmann & Peter G. Thirolf - 52-57 Principles underlying sensory map topography in primary visual cortex
by Jens Kremkow & Jianzhong Jin & Yushi Wang & Jose M. Alonso - 58-63 Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance
by Ahmed H. Badran & Victor M. Guzov & Qing Huai & Melissa M. Kemp & Prashanth Vishwanath & Wendy Kain & Autumn M. Nance & Artem Evdokimov & Farhad Moshiri & Keith H. Turner & Ping Wang & Thomas Malvar & David R. Liu - 64-67 Resolved atomic lines reveal outflows in two ultraluminous X-ray sources
by Ciro Pinto & Matthew J. Middleton & Andrew C. Fabian - 68-72 Polar metals by geometric design
by T. H. Kim & D. Puggioni & Y. Yuan & L. Xie & H. Zhou & N. Campbell & P. J. Ryan & Y. Choi & J.-W. Kim & J. R. Patzner & S. Ryu & J. P. Podkaminer & J. Irwin & Y. Ma & C. J. Fennie & M. S. Rzchowski & X. Q. Pan & V. Gopalan & J. M. Rondinelli & C. B. Eom - 73-76 Machine-learning-assisted materials discovery using failed experiments
by Paul Raccuglia & Katherine C. Elbert & Philip D. F. Adler & Casey Falk & Malia B. Wenny & Aurelio Mollo & Matthias Zeller & Sorelle A. Friedler & Joshua Schrier & Alexander J. Norquist - 77-81 Scalable and sustainable electrochemical allylic C–H oxidation
by Evan J. Horn & Brandon R. Rosen & Yong Chen & Jiaze Tang & Ke Chen & Martin D. Eastgate & Phil S. Baran - 82-85 Chondritic xenon in the Earth’s mantle
by Antonio Caracausi & Guillaume Avice & Peter G. Burnard & Evelyn Füri & Bernard Marty - 86-89 The genetic program for cartilage development has deep homology within Bilateria
by Oscar A. Tarazona & Leslie A. Slota & Davys H. Lopez & GuangJun Zhang & Martin J. Cohn - 90-94 Topology of ON and OFF inputs in visual cortex enables an invariant columnar architecture
by Kuo-Sheng Lee & Xiaoying Huang & David Fitzpatrick - 95-99 Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
by Frank Soldner & Yonatan Stelzer & Chikdu S. Shivalila & Brian J. Abraham & Jeanne C. Latourelle & M. Inmaculada Barrasa & Johanna Goldmann & Richard H. Myers & Richard A. Young & Rudolf Jaenisch - 100-104 Unique human immune signature of Ebola virus disease in Guinea
by Paula Ruibal & Lisa Oestereich & Anja Lüdtke & Beate Becker-Ziaja & David M. Wozniak & Romy Kerber & Miša Korva & Mar Cabeza-Cabrerizo & Joseph A. Bore & Fara Raymond Koundouno & Sophie Duraffour & Romy Weller & Anja Thorenz & Eleonora Cimini & Domenico Viola & Chiara Agrati & Johanna Repits & Babak Afrough & Lauren A. Cowley & Didier Ngabo & Julia Hinzmann & Marc Mertens & Inês Vitoriano & Christopher H. Logue & Jan Peter Boettcher & Elisa Pallasch & Andreas Sachse & Amadou Bah & Katja Nitzsche & Eeva Kuisma & Janine Michel & Tobias Holm & Elsa-Gayle Zekeng & Isabel García-Dorival & Roman Wölfel & Kilian Stoecker & Erna Fleischmann & Thomas Strecker & Antonino Di Caro & Tatjana Avšič-Županc & Andreas Kurth & Silvia Meschi & Stephane Mély & Edmund Newman & Anne Bocquin & Zoltan Kis & Anne Kelterbaum & Peter Molkenthin & Fabrizio Carletti & Jasmine Portmann & Svenja Wolff & Concetta Castilletti & Gordian Schudt & Alexandra Fizet & Lisa J. Ottowell & Eva Herker & Thomas Jacobs & Birte Kretschmer & Ettore Severi & Nobila Ouedraogo & Mar Lago & Anabel Negredo & Leticia Franco & Pedro Anda & Stefan Schmiedel & Benno Kreuels & Dominic Wichmann & Marylyn M. Addo & Ansgar W. Lohse & Hilde De Clerck & Carolina Nanclares & Sylvie Jonckheere & Michel Van Herp & Armand Sprecher & Gao Xiaojiang & Mary Carrington & Osvaldo Miranda & Carlos M. Castro & Martin Gabriel & Patrick Drury & Pierre Formenty & Boubacar Diallo & Lamine Koivogui & N’Faly Magassouba & Miles W. Carroll & Stephan Günther & César Muñoz-Fontela - 105-109 A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
by Rajeev Gautam & Yoshiaki Nishimura & Amarendra Pegu & Martha C. Nason & Florian Klein & Anna Gazumyan & Jovana Golijanin & Alicia Buckler-White & Reza Sadjadpour & Keyun Wang & Zachary Mankoff & Stephen D. Schmidt & Jeffrey D. Lifson & John R. Mascola & Michel C. Nussenzweig & Malcolm A. Martin - 110-114 EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells
by Jianhua Li & Erick Lu & Tangsheng Yi & Jason G. Cyster - 115-119 RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells
by Jennifer Martinez & Larissa D. Cunha & Sunmin Park & Mao Yang & Qun Lu & Robert Orchard & Quan-Zhen Li & Mei Yan & Laura Janke & Cliff Guy & Andreas Linkermann & Herbert W. Virgin & Douglas R. Green - 120-124 Ubiquitination independent of E1 and E2 enzymes by bacterial effectors
by Jiazhang Qiu & Michael J. Sheedlo & Kaiwen Yu & Yunhao Tan & Ernesto S. Nakayasu & Chittaranjan Das & Xiaoyun Liu & Zhao-Qing Luo - 125-129 Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9
by Dominik Paquet & Dylan Kwart & Antonia Chen & Andrew Sproul & Samson Jacob & Shaun Teo & Kimberly Moore Olsen & Andrew Gregg & Scott Noggle & Marc Tessier-Lavigne - 130-130 Correction: Corrigendum: Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans
by Sreekanth H. Chalasani & Nikos Chronis & Makoto Tsunozaki & Jesse M. Gray & Daniel Ramot & Miriam B. Goodman & Cornelia I. Bargmann - 130-130 Correction: Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions
by Wendy Huang & Benjamin Thomas & Ryan A. Flynn & Samuel J. Gavzy & Lin Wu & Sangwon V. Kim & Jason A. Hall & Emily R. Miraldi & Charles P. Ng & Frank Rigo & Sarah Meadows & Nina R. Montoya & Natalia G. Herrera & Ana I. Domingos & Fraydoon Rastinejad & Richard M. Myers & Frances V. Fuller-Pace & Richard Bonneau & Howard Y. Chang & Oreste Acuto & Dan R. Littman - 130-130 Correction: Corrigendum: Discovery of Atg5/Atg7-independent alternative macroautophagy
by Yuya Nishida & Satoko Arakawa & Kenji Fujitani & Hirofumi Yamaguchi & Takeshi Mizuta & Toku Kanaseki & Masaaki Komatsu & Kinya Otsu & Yoshihide Tsujimoto & Shigeomi Shimizu - 131-132 The struggle with image glut
by Jeffrey M. Perkel - 133-135 Relationships: Scions of science
by Amber Dance - 138-138 The Museum of Nothing
by Anna Zumbro
April 2016, Volume 532, Issue 7600
- 1-1 Saudi Arabia
by Mohammed Yahia - 2-3 Sights set on a central role
by Larissa Kogleck - 4-9 A 21st century transformation
by Sedeer El-Showk - 10-12 Making the most of financial might
by Pakinam Amer - 13-15 Oiling the wheels on a road to success
by Pakinam Amer - 16-18 Shared knowledge is key to a kingdom
by Nadia El-Awady - 19-21 Making the most of local expertise
by Nadia El-Awady - 415-415 Speak up about subtle sexism in science
by Tricia Serio - 421-422 Devastating wheat fungus appears in Asia for first time
by Ewen Callaway - 422-423 AI talent grab sparks excitement and concern
by Elizabeth Gibney - 424-425 Scientists worry as cancer moonshots multiply
by Erika Check Hayden - 425-425 Researchers push for personalized tumour vaccines
by Heidi Ledford - 426-426 Europe plans giant billion-euro quantum technologies project
by Elizabeth Gibney - 427-427 AstraZeneca launches project to sequence 2 million genomes
by Heidi Ledford - 428-431 Killer landslides: The lasting legacy of Nepal’s quake
by Jane Qiu - 432-434 The quiet revolutionary: How the co-discovery of CRISPR explosively changed Emmanuelle Charpentier’s life
by Alison Abbott - 435-437 Seven chemical separations to change the world
by David S. Sholl & Ryan P. Lively - 438-439 Technology: Beyond the 'InterNyet'
by Michael D. Gordin - 439-439 Books in brief
by Barbara Kiser - 440-440 Zoology: In the museum with Roosevelt
by Michael Ross Canfield - 441-441 Benefits of trade in amber fossils
by Jun Chen & Bo Wang & Edmund A. Jarzembowski - 441-441 Postdoc rights need not hurt productivity
by Nuno Cerca - 441-441 Anti-science wave sweeps Poland
by Paula Dobosz & Jakub Zawiła-Niedźwiecki - 441-441 Tell us the end of the story
by M. Usman & A. Chaudhary & M. Farooq - 441-441 Ventilating Beijing cannot fix pollution
by Yansui Liu & Yang Zhou & Yurui Li - 442-442 R. McNeill Alexander (1934–2016)
by Andrew A. Biewener & Alan Wilson - 444-445 The rise of Rhizaria
by David A. Caron - 445-446 Cracks help membranes to stay hydrated
by Jovan Kamcev & Benny D. Freeman - 447-448 Getting the measure of a monster
by Shigeru Kuratani & Tatsuya Hirasawa - 449-449 Four neutrons together momentarily
by Carlos A. Bertulani & Vladimir Zelevinsky - 449-450 Fault tolerance in the brain
by Byron M. Yu - 450-451 Glitches in time
by Charlotte A. L. Haley - 453-458 Natural speech reveals the semantic maps that tile human cerebral cortex
by Alexander G. Huth & Wendy A. de Heer & Thomas L. Griffiths & Frédéric E. Theunissen & Jack L. Gallant - 459-464 Robust neuronal dynamics in premotor cortex during motor planning
by Nuo Li & Kayvon Daie & Karel Svoboda & Shaul Druckmann - 465-470 Plankton networks driving carbon export in the oligotrophic ocean
by Lionel Guidi & Samuel Chaffron & Lucie Bittner & Damien Eveillard & Abdelhalim Larhlimi & Simon Roux & Youssef Darzi & Stephane Audic & Léo Berline & Jennifer R. Brum & Luis Pedro Coelho & Julio Cesar Ignacio Espinoza & Shruti Malviya & Shinichi Sunagawa & Céline Dimier & Stefanie Kandels-Lewis & Marc Picheral & Julie Poulain & Sarah Searson & Lars Stemmann & Fabrice Not & Pascal Hingamp & Sabrina Speich & Mick Follows & Lee Karp-Boss & Emmanuel Boss & Hiroyuki Ogata & Stephane Pesant & Jean Weissenbach & Patrick Wincker & Silvia G. Acinas & Peer Bork & Colomban de Vargas & Daniele Iudicone & Matthew B. Sullivan & Jeroen Raes & Eric Karsenti & Chris Bowler & Gabriel Gorsky - 471-475 Dynamics from noisy data with extreme timing uncertainty
by R. Fung & A. M. Hanna & O. Vendrell & S. Ramakrishna & T. Seideman & R. Santra & A. Ourmazd - 476-479 Quantum phases from competing short- and long-range interactions in an optical lattice
by Renate Landig & Lorenz Hruby & Nishant Dogra & Manuele Landini & Rafael Mottl & Tobias Donner & Tilman Esslinger - 480-483 Nanocrack-regulated self-humidifying membranes
by Chi Hoon Park & So Young Lee & Doo Sung Hwang & Dong Won Shin & Doo Hee Cho & Kang Hyuck Lee & Tae-Woo Kim & Tae-Wuk Kim & Mokwon Lee & Deok-Soo Kim & Cara M. Doherty & Aaron W. Thornton & Anita J. Hill & Michael D. Guiver & Young Moo Lee - 484-488 The pentadehydro-Diels–Alder reaction
by Teng Wang & Rajasekhar Reddy Naredla & Severin K. Thompson & Thomas R. Hoye - 489-491 Rapid cycling of reactive nitrogen in the marine boundary layer
by Chunxiang Ye & Xianliang Zhou & Dennis Pu & Jochen Stutz & James Festa & Max Spolaor & Catalina Tsai & Christopher Cantrell & Roy L. Mauldin & Teresa Campos & Andrew Weinheimer & Rebecca S. Hornbrook & Eric C. Apel & Alex Guenther & Lisa Kaser & Bin Yuan & Thomas Karl & Julie Haggerty & Samuel Hall & Kirk Ullmann & James N. Smith & John Ortega & Christoph Knote - 492-495 Bubble accumulation and its role in the evolution of magma reservoirs in the upper crust
by A. Parmigiani & S. Faroughi & C. Huber & O. Bachmann & Y. Su - 496-499 The ‘Tully monster’ is a vertebrate
by Victoria E. McCoy & Erin E. Saupe & James C. Lamsdell & Lidya G. Tarhan & Sean McMahon & Scott Lidgard & Paul Mayer & Christopher D. Whalen & Carmen Soriano & Lydia Finney & Stefan Vogt & Elizabeth G. Clark & Ross P. Anderson & Holger Petermann & Emma R. Locatelli & Derek E. G. Briggs - 500-503 The eyes of Tullimonstrum reveal a vertebrate affinity
by Thomas Clements & Andrei Dolocan & Peter Martin & Mark A. Purnell & Jakob Vinther & Sarah E. Gabbott - 504-507 In situ imaging reveals the biomass of giant protists in the global ocean
by Tristan Biard & Lars Stemmann & Marc Picheral & Nicolas Mayot & Pieter Vandromme & Helena Hauss & Gabriel Gorsky & Lionel Guidi & Rainer Kiko & Fabrice Not - 508-511 Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells
by Stefan Rentas & Nicholas T. Holzapfel & Muluken S. Belew & Gabriel A. Pratt & Veronique Voisin & Brian T. Wilhelm & Gary D. Bader & Gene W. Yeo & Kristin J. Hope - 512-516 Normalizing the environment recapitulates adult human immune traits in laboratory mice
by Lalit K. Beura & Sara E. Hamilton & Kevin Bi & Jason M. Schenkel & Oludare A. Odumade & Kerry A. Casey & Emily A. Thompson & Kathryn A. Fraser & Pamela C. Rosato & Ali Filali-Mouhim & Rafick P. Sekaly & Marc K. Jenkins & Vaiva Vezys & W. Nicholas Haining & Stephen C. Jameson & David Masopust - 517-521 The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
by Ines Fonfara & Hagen Richter & Majda Bratovič & Anaïs Le Rhun & Emmanuelle Charpentier - 522-526 The crystal structure of Cpf1 in complex with CRISPR RNA
by De Dong & Kuan Ren & Xiaolin Qiu & Jianlin Zheng & Minghui Guo & Xiaoyu Guan & Hongnan Liu & Ningning Li & Bailing Zhang & Daijun Yang & Chuang Ma & Shuo Wang & Dan Wu & Yunfeng Ma & Shilong Fan & Jiawei Wang & Ning Gao & Zhiwei Huang - 527-530 Crystal structure of the human σ1 receptor
by Hayden R. Schmidt & Sanduo Zheng & Esin Gurpinar & Antoine Koehl & Aashish Manglik & Andrew C. Kruse - 531-533 Non-profit work: Take my advice
by Chris Woolston - 533-533 Turning point: Carpe freedom
by Virginia Gewin - 536-536 A slice of time
by Jeff Hecht
April 2016, Volume 532, Issue 7599
- 283-283 The Paris Agreement has solved a troubling problem
by Simon L. Lewis - 289-290 Gene-editing research in human embryos gains momentum
by Ewen Callaway - 290-291 North Korea lets scientists peer inside dangerous volcano
by Alexandra Witze - 291-291 Multibillion-euro innovation hub slammed by auditors
by Quirin Schiermeier - 292-292 Synthetic biology tackles global antivenom shortage
by Carrie Arnold - 293-293 Gene-edited CRISPR mushroom escapes US regulation
by Emily Waltz - 294-295 Dirty room-mates make lab mice more useful
by Sara Reardon - 296-299 Cold truths at the top of the world
by Julia Rosen - 300-302 Monkey kingdom
by David Cyranoski