IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v535y2016i7611d10.1038_nature18610.html
   My bibliography  Save this article

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes

Author

Listed:
  • Sara Cuylen

    (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC))

  • Claudia Blaukopf

    (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC))

  • Antonio Z. Politi

    (Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL))

  • Thomas Müller-Reichert

    (Medical Faculty Carl Gustav Carus, Experimental Center, Technische Universität Dresden)

  • Beate Neumann

    (Advanced Light Microscopy Facility, European Molecular Biology Laboratory (EMBL))

  • Ina Poser

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Jan Ellenberg

    (Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL))

  • Anthony A. Hyman

    (Max Planck Institute of Molecular Cell Biology and Genetics)

  • Daniel W. Gerlich

    (Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC))

Abstract

During cell division, chromosomes are maintained as individual units; this process is shown to be mediated by the cell proliferation marker Ki-67, which has biophysical properties similar to those of surfactants.

Suggested Citation

  • Sara Cuylen & Claudia Blaukopf & Antonio Z. Politi & Thomas Müller-Reichert & Beate Neumann & Ina Poser & Jan Ellenberg & Anthony A. Hyman & Daniel W. Gerlich, 2016. "Ki-67 acts as a biological surfactant to disperse mitotic chromosomes," Nature, Nature, vol. 535(7611), pages 308-312, July.
    • Handle: RePEc:nat:nature:v:535:y:2016:i:7611:d:10.1038_nature18610
    DOI: 10.1038/nature18610
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature18610
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature18610?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Kayo Hibino & Yuji Sakai & Sachiko Tamura & Masatoshi Takagi & Katsuhiko Minami & Toyoaki Natsume & Masa A. Shimazoe & Masato T. Kanemaki & Naoko Imamoto & Kazuhiro Maeshima, 2024. "Single-nucleosome imaging unveils that condensins and nucleosome–nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    2. Ravi Chawla & Jenna K. A. Tom & Tumara Boyd & Nicholas H. Tu & Tanxi Bai & Danielle A. Grotjahn & Donghyun Park & Ashok A. Deniz & Lisa R. Racki, 2024. "Reentrant DNA shells tune polyphosphate condensate size," Nature Communications, Nature, vol. 15(1), pages 1-15, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:535:y:2016:i:7611:d:10.1038_nature18610. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.