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Content
September 2016, Volume 537, Issue 7619
- 170-171 Designing the ideal opioid
by Brigitte L. Kieffer - 171-172 Slippery when narrow
by Angelos Michaelides - 172-173 Mapping the terrestrial human footprint
by Philip J. K. McGowan - 174-175 Violent emissions of newborn stars
by Markus Röllig - 175-176 Catalytic spliceosome captured
by Brian Kosmyna & Charles C. Query - 176-177 Fin to limb within our grasp
by Aditya Saxena & Kimberly L. Cooper - 179-184 Photocontrol of fluid slugs in liquid crystal polymer microactuators
by Jiu-an Lv & Yuyun Liu & Jia Wei & Erqiang Chen & Lang Qin & Yanlei Yu - 185-190 Structure-based discovery of opioid analgesics with reduced side effects
by Aashish Manglik & Henry Lin & Dipendra K. Aryal & John D. McCorvy & Daniela Dengler & Gregory Corder & Anat Levit & Ralf C. Kling & Viachaslau Bernat & Harald Hübner & Xi-Ping Huang & Maria F. Sassano & Patrick M. Giguère & Stefan Löber & Da Duan & Grégory Scherrer & Brian K. Kobilka & Peter Gmeiner & Bryan L. Roth & Brian K. Shoichet - 191-196 Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
by Jianping Wu & Zhen Yan & Zhangqiang Li & Xingyang Qian & Shan Lu & Mengqiu Dong & Qiang Zhou & Nieng Yan - 197-201 Cryo-EM structure of the spliceosome immediately after branching
by Wojciech P. Galej & Max E. Wilkinson & Sebastian M. Fica & Chris Oubridge & Andrew J. Newman & Kiyoshi Nagai - 202-206 Structural basis for the antifolding activity of a molecular chaperone
by Chengdong Huang & Paolo Rossi & Tomohide Saio & Charalampos G. Kalodimos - 207-209 Compression and ablation of the photo-irradiated molecular cloud the Orion Bar
by Javier R. Goicoechea & Jérôme Pety & Sara Cuadrado & José Cernicharo & Edwige Chapillon & Asunción Fuente & Maryvonne Gerin & Christine Joblin & Nuria Marcelino & Paolo Pilleri - 210-213 Massive radius-dependent flow slippage in carbon nanotubes
by Eleonora Secchi & Sophie Marbach & Antoine Niguès & Derek Stein & Alessandro Siria & Lydéric Bocquet - 214-219 Oxidative diversification of amino acids and peptides by small-molecule iron catalysis
by Thomas J. Osberger & Donald C. Rogness & Jeffrey T. Kohrt & Antonia F. Stepan & M. Christina White - 220-224 A progressively wetter climate in southern East Africa over the past 1.3 million years
by T. C. Johnson & J. P. Werne & E. T. Brown & A. Abbott & M. Berke & B. A. Steinman & J. Halbur & S. Contreras & S. Grosshuesch & A. Deino & C. A. Scholz & R. P. Lyons & S. Schouten & J. S. Sinninghe Damsté - 225-228 Digits and fin rays share common developmental histories
by Tetsuya Nakamura & Andrew R. Gehrke & Justin Lemberg & Julie Szymaszek & Neil H. Shubin - 229-233 Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
by Shilpi Khare & Advait S. Nagle & Agnes Biggart & Yin H. Lai & Fang Liang & Lauren C. Davis & S. Whitney Barnes & Casey J. N. Mathison & Elmarie Myburgh & Mu-Yun Gao & J. Robert Gillespie & Xianzhong Liu & Jocelyn L. Tan & Monique Stinson & Ianne C. Rivera & Jaime Ballard & Vince Yeh & Todd Groessl & Glenn Federe & Hazel X. Y. Koh & John D. Venable & Badry Bursulaya & Michael Shapiro & Pranab K. Mishra & Glen Spraggon & Ansgar Brock & Jeremy C. Mottram & Frederick S. Buckner & Srinivasa P. S. Rao & Ben G. Wen & John R. Walker & Tove Tuntland & Valentina Molteni & Richard J. Glynne & Frantisek Supek - 234-238 Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
by Sung Hoon Cho & Ariel L. Raybuck & Kristy Stengel & Mei Wei & Thomas C. Beck & Emmanuel Volanakis & James W. Thomas & Scott Hiebert & Volker H. Haase & Mark R. Boothby - 239-243 The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan
by Jonathan J. Kotzin & Sean P. Spencer & Sam J. McCright & Dinesh B. Uthaya Kumar & Magalie A. Collet & Walter K. Mowel & Ellen N. Elliott & Asli Uyar & Michelle A. Makiya & Margaret C. Dunagin & Christian C. D. Harman & Anthony T. Virtue & Stella Zhu & Will Bailis & Judith Stein & Cynthia Hughes & Arjun Raj & E. John Wherry & Loyal A. Goff & Amy D. Klion & John L. Rinn & Adam Williams & Richard A. Flavell & Jorge Henao-Mejia - 244-248 PionX sites mark the X chromosome for dosage compensation
by Raffaella Villa & Tamas Schauer & Pawel Smialowski & Tobias Straub & Peter B. Becker - 249-253 Insights from biochemical reconstitution into the architecture of human kinetochores
by John R. Weir & Alex C. Faesen & Kerstin Klare & Arsen Petrovic & Federica Basilico & Josef Fischböck & Satyakrishna Pentakota & Jenny Keller & Marion E. Pesenti & Dongqing Pan & Doro Vogt & Sabine Wohlgemuth & Franz Herzog & Andrea Musacchio - 254-254 Correction: Corrigendum: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
by Amanpreet Kaur & Marie R. Webster & Katie Marchbank & Reeti Behera & Abibatou Ndoye & Curtis H. Kugel & Vanessa M. Dang & Jessica Appleton & Michael P. O’Connell & Phil Cheng & Alexander A. Valiga & Rachel Morissette & Nazli B. McDonnell & Luigi Ferrucci & Andrew V. Kossenkov & Katrina Meeth & Hsin-Yao Tang & Xiangfan Yin & William H. Wood & Elin Lehrmann & Kevin G. Becker & Keith T. Flaherty & Dennie T. Frederick & Jennifer A. Wargo & Zachary A. Cooper & Michael T. Tetzlaff & Courtney Hudgens & Katherine M. Aird & Rugang Zhang & Xiaowei Xu & Qin Liu & Edmund Bartlett & Giorgos Karakousis & Zeynep Eroglu & Roger S. Lo & Matthew Chan & Alexander M. Menzies & Georgina V. Long & Douglas B. Johnson & Jeffrey Sosman & Bastian Schilling & Dirk Schadendorf & David W. Speicher & Marcus Bosenberg & Antoni Ribas & Ashani T. Weeraratna - 254-254 Correction: Corrigendum: Malaria: Thermoregulation in a parasite’s life cycle
by Jun Fang & Thomas F. McCutchan - 254-254 Correction: Corrigendum: Enhancer loops appear stable during development and are associated with paused polymerase
by Yad Ghavi-Helm & Felix A. Klein & Tibor Pakozdi & Lucia Ciglar & Daan Noordermeer & Wolfgang Huber & Eileen E. M. Furlong - 255-257 Lab life: Daydream and discover
by Emily Sohn - 257-257 Trade talk: Star selector
by Monya Baker - 259-270 Try catch throw
by Andrew Neil Gray
September 2016, Volume 537, Issue 7618
- 1-1 Science-led economies
by Herb Brody - 1-2 Verifying quantum superpositions at metre scales
by D. M. Stamper-Kurn & G. E. Marti & H. Müller - 2-3 Kovachy et al. reply
by T. Kovachy & P. Asenbaum & C. Overstreet & C. A. Donnelly & S. M. Dickerson & A. Sugarbaker & J. M. Hogan & M. A. Kasevich - 2-3 Big science spenders
by Alla Katsnelson - 4-5 Questioning Holocene community shifts
by Cleo Bertelsmeier & Sébastien Ollier - 4-5 Rwanda: From killing fields to technopolis
by Linda Nordling - 5-6 Lyons et al. reply
by S. Kathleen Lyons & Joshua H. Miller & Anikó Tóth & Kathryn L. Amatangelo & Anna K. Behrensmeyer & Antoine Bercovici & Jessica L. Blois & Matt Davis & William A. DiMichelle & Andrew Du & Jussi T. Eronen & J. Tyler Faith & Gary R. Graves & Nathan Jud & Conrad Labandeira & Cindy V. Looy & Brian McGill & David Patterson & Silvia Pineda-Munoz & Richard Potts & Brett Riddle & Rebecca Terry & Werner Ulrich & Amelia Villaseñor & Scott Wing & Heidi Anderson & John Anderson & Nicholas J. Gotelli - 6-7 The Middle East: An end to oil dependency
by Louise Sarant - 8-9 China: High-tech transformation
by Annabel McGilvray - 9-9 Preserve personal freedom in networked societies
by Christoph Bock - 10-11 Russia: A faltering recovery
by Olga Dobrovidova - 12-13 Germany: Equality or excellence
by Anja Krieger - 14-15 Australia: Balancing act
by Bianca Nogrady - 15-16 Italian scientists shocked by earthquake devastation
by Alison Abbott & Quirin Schiermeier - 16-17 Nuclear power plants prepare for old age
by Jeff Tollefson - 16-17 Singapore: The brain-gain game
by Annabel McGilvray - 18-19 Massachusetts: Mass effect
by Neil Savage - 19-20 Print your own 3D Lucy to work out how the famous hominin died
by Ewen Callaway - 20-20 Perspective: Fix the incentives
by Julia Lane - 20-21 Majority of mathematicians hail from just 24 scientific ‘families’
by Davide Castelvecchi - 22-24 How DNA could store all the world’s data
by Andy Extance - 26-28 Vipers, mambas and taipans: the escalating health crisis over snakebites
by Carrie Arnold - 29-30 Stop ignoring misconduct
by Donald S. Kornfeld & Sandra L. Titus - 32-33 In retrospect: A New System of Chemical Philosophy
by Philip Ball - 33-33 Books in brief
by Barbara Kiser - 34-34 Could Pokémon Go boost birding?
by Fabio de Oliveira Roque - 34-34 Stuck between a rock and a hard place
by Yingchao Hu & Liangjun Hu - 34-34 Rate oceans' capital to help achieve SDGs
by Yonglong Lu - 34-34 Hallmark labs with a replicability record
by Mattia Andreoletti - 34-34 Fallacy of perfection harms peer review
by James C. Zimring & Steven L. Spitalnik - 36-37 Attack on amyloid-β protein
by Eric M. Reiman - 37-38 Cometary dust under the microscope
by Ludmilla Kolokolova - 38-40 Moulding the ribosome
by Marlene Oeffinger - 40-41 Southern Ocean freshened by sea ice
by Ted Maksym - 42-42 More is less
by Ryan Wilkinson - 42-43 Suffocation of gene expression
by Dan Ye & Yue Xiong - 43-44 Muddy messages about American migration
by Suzanne McGowan - 45-49 Postglacial viability and colonization in North America’s ice-free corridor
by Mikkel W. Pedersen & Anthony Ruter & Charles Schweger & Harvey Friebe & Richard A. Staff & Kristian K. Kjeldsen & Marie L. Z. Mendoza & Alwynne B. Beaudoin & Cynthia Zutter & Nicolaj K. Larsen & Ben A. Potter & Rasmus Nielsen & Rebecca A. Rainville & Ludovic Orlando & David J. Meltzer & Kurt H. Kjær & Eske Willerslev - 50-56 The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease
by Jeff Sevigny & Ping Chiao & Thierry Bussière & Paul H. Weinreb & Leslie Williams & Marcel Maier & Robert Dunstan & Stephen Salloway & Tianle Chen & Yan Ling & John O’Gorman & Fang Qian & Mahin Arastu & Mingwei Li & Sowmya Chollate & Melanie S. Brennan & Omar Quintero-Monzon & Robert H. Scannevin & H. Moore Arnold & Thomas Engber & Kenneth Rhodes & James Ferrero & Yaming Hang & Alvydas Mikulskis & Jan Grimm & Christoph Hock & Roger M. Nitsch & Alfred Sandrock - 57-62 A developmental coordinate of pluripotency among mice, monkeys and humans
by Tomonori Nakamura & Ikuhiro Okamoto & Kotaro Sasaki & Yukihiro Yabuta & Chizuru Iwatani & Hideaki Tsuchiya & Yasunari Seita & Shinichiro Nakamura & Takuya Yamamoto & Mitinori Saitou - 63-68 Tumour hypoxia causes DNA hypermethylation by reducing TET activity
by Bernard Thienpont & Jessica Steinbacher & Hui Zhao & Flora D’Anna & Anna Kuchnio & Athanasios Ploumakis & Bart Ghesquière & Laurien Van Dyck & Bram Boeckx & Luc Schoonjans & Els Hermans & Frederic Amant & Vessela N. Kristensen & Kian Peng Koh & Massimiliano Mazzone & Mathew L. Coleman & Thomas Carell & Peter Carmeliet & Diether Lambrechts - 69-72 A combined transmission spectrum of the Earth-sized exoplanets TRAPPIST-1 b and c
by Julien de Wit & Hannah R. Wakeford & Michaël Gillon & Nikole K. Lewis & Jeff A. Valenti & Brice-Olivier Demory & Adam J. Burgasser & Artem Burdanov & Laetitia Delrez & Emmanuël Jehin & Susan M. Lederer & Didier Queloz & Amaury H. M. J. Triaud & Valérie Van Grootel - 73-75 Aggregate dust particles at comet 67P/Churyumov–Gerasimenko
by Mark S. Bentley & Roland Schmied & Thurid Mannel & Klaus Torkar & Harald Jeszenszky & Jens Romstedt & Anny-Chantal Levasseur-Regourd & Iris Weber & Elmar K. Jessberger & Pascale Ehrenfreund & Christian Koeberl & Ove Havnes - 76-79 Dynamically encircling an exceptional point for asymmetric mode switching
by Jörg Doppler & Alexei A. Mailybaev & Julian Böhm & Ulrich Kuhl & Adrian Girschik & Florian Libisch & Thomas J. Milburn & Peter Rabl & Nimrod Moiseyev & Stefan Rotter - 80-83 Topological energy transfer in an optomechanical system with exceptional points
by H. Xu & D. Mason & Luyao Jiang & J. G. E. Harris - 84-88 Ablation-cooled material removal with ultrafast bursts of pulses
by Can Kerse & Hamit Kalaycıoğlu & Parviz Elahi & Barbaros Çetin & Denizhan K. Kesim & Önder Akçaalan & Seydi Yavaş & Mehmet D. Aşık & Bülent Öktem & Heinar Hoogland & Ronald Holzwarth & Fatih Ömer Ilday - 89-92 Sea-ice transport driving Southern Ocean salinity and its recent trends
by F. Alexander Haumann & Nicolas Gruber & Matthias Münnich & Ivy Frenger & Stefan Kern - 93-96 Addition of multiple limiting resources reduces grassland diversity
by W. Stanley Harpole & Lauren L. Sullivan & Eric M. Lind & Jennifer Firn & Peter B. Adler & Elizabeth T. Borer & Jonathan Chase & Philip A. Fay & Yann Hautier & Helmut Hillebrand & Andrew S. MacDougall & Eric W. Seabloom & Ryan Williams & Jonathan D. Bakker & Marc W. Cadotte & Enrique J. Chaneton & Chengjin Chu & Elsa E. Cleland & Carla D’Antonio & Kendi F. Davies & Daniel S. Gruner & Nicole Hagenah & Kevin Kirkman & Johannes M. H. Knops & Kimberly J. La Pierre & Rebecca L. McCulley & Joslin L. Moore & John W. Morgan & Suzanne M. Prober & Anita C. Risch & Martin Schuetz & Carly J. Stevens & Peter D. Wragg - 97-101 Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala
by Catherine A. Marcinkiewcz & Christopher M. Mazzone & Giuseppe D’Agostino & Lindsay R. Halladay & J. Andrew Hardaway & Jeffrey F. DiBerto & Montserrat Navarro & Nathan Burnham & Claudia Cristiano & Cayce E. Dorrier & Gregory J. Tipton & Charu Ramakrishnan & Tamas Kozicz & Karl Deisseroth & Todd E. Thiele & Zoe A. McElligott & Andrew Holmes & Lora K. Heisler & Thomas L. Kash - 102-106 HER2 expression identifies dynamic functional states within circulating breast cancer cells
by Nicole Vincent Jordan & Aditya Bardia & Ben S. Wittner & Cyril Benes & Matteo Ligorio & Yu Zheng & Min Yu & Tilak K. Sundaresan & Joseph A. Licausi & Rushil Desai & Ryan M. O’Keefe & Richard Y. Ebright & Myriam Boukhali & Srinjoy Sil & Maristela L. Onozato & Anthony J. Iafrate & Ravi Kapur & Dennis Sgroi & David T. Ting & Mehmet Toner & Sridhar Ramaswamy & Wilhelm Haas & Shyamala Maheswaran & Daniel A. Haber - 107-111 An endosomal tether undergoes an entropic collapse to bring vesicles together
by David H. Murray & Marcus Jahnel & Janelle Lauer & Mario J. Avellaneda & Nicolas Brouilly & Alice Cezanne & Hernán Morales-Navarrete & Enrico D. Perini & Charles Ferguson & Andrei N. Lupas & Yannis Kalaidzidis & Robert G. Parton & Stephan W. Grill & Marino Zerial - 112-116 Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling
by Neil S. Dhawan & Alex P. Scopton & Arvin C. Dar - 117-121 Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs
by Lin Tang & Tamer M. Gamal El-Din & Teresa M. Swanson & David C. Pryde & Todd Scheuer & Ning Zheng & William A. Catterall - 122-122 Correction: Corrigendum: Robust neuronal dynamics in premotor cortex during motor planning
by Nuo Li & Kayvon Daie & Karel Svoboda & Shaul Druckmann - 122-122 Correction: Corrigendum: Convection in a volatile nitrogen-ice-rich layer drives Pluto’s geological vigour
by William B. McKinnon & Francis Nimmo & Teresa Wong & Paul M. Schenk & Oliver L. White & J. H. Roberts & J. M. Moore & J. R. Spencer & A. D. Howard & O. M. Umurhan & S. A. Stern & H. A. Weaver & C. B. Olkin & L. A. Young & K. E. Smith - 122-122 Correction: Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis
by Beatriz Baragaña & Irene Hallyburton & Marcus C. S. Lee & Neil R. Norcross & Raffaella Grimaldi & Thomas D. Otto & William R. Proto & Andrew M. Blagborough & Stephan Meister & Grennady Wirjanata & Andrea Ruecker & Leanna M. Upton & Tara S. Abraham & Mariana J. Almeida & Anupam Pradhan & Achim Porzelle & María Santos Martínez & Judith M. Bolscher & Andrew Woodland & Torsten Luksch & Suzanne Norval & Fabio Zuccotto & John Thomas & Frederick Simeons & Laste Stojanovski & Maria Osuna-Cabello & Paddy M. Brock & Tom S. Churcher & Katarzyna A. Sala & Sara E. Zakutansky & María Belén Jiménez-Díaz & Laura Maria Sanz & Jennifer Riley & Rajshekhar Basak & Michael Campbell & Vicky M. Avery & Robert W. Sauerwein & Koen J. Dechering & Rintis Noviyanti & Brice Campo & Julie A. Frearson & Iñigo Angulo-Barturen & Santiago Ferrer-Bazaga & Francisco Javier Gamo & Paul G. Wyatt & Didier Leroy & Peter Siegl & Michael J. Delves & Dennis E. Kyle & Sergio Wittlin & Jutta Marfurt & Ric N. Price & Robert E. Sinden & Elizabeth A. Winzeler & Susan A. Charman & Lidiya Bebrevska & David W. Gray & Simon Campbell & Alan H. Fairlamb & Paul A. Willis & Julian C. Rayner & David A. Fidock & Kevin D. Read & Ian H. Gilbert - 123-124 Computers on the reef
by Jeff Tollefson - 125-126 Art–science collaborations: Change of perspective
by Sheila Mulrooney Eldred - 128-128 Skin hunger
by Bo Balder
August 2016, Volume 536, Issue 7617
- 1-1 Career guide: Asia-Pacific
by Nic Fleming - 1-3 Isotopic composition of plant water sources
by Mathieu Javaux & Youri Rothfuss & Jan Vanderborght & Harry Vereecken & Nicolas Brüggemann - 3-3 Evaristo et al. reply
by J. Evaristo & S. Jasechko & J. J. McDonnell - 6-8 China
by Rebecca Kanthor - 14-16 Japan
by Smriti Mallapaty - 18-20 Australia
by Karen McGhee - 22-23 South Korea
by Mark Zastrow - 26-27 India
by T.V. Padma - 28-29 Singapore
by Tom Benner - 30-31 New Zealand
by Annabel McGilvray - 375-375 China's soil plan needs strong support
by Hong Yang - 381-382 Earth-sized planet around nearby star is astronomy dream come true
by Alexandra Witze - 382-382 US personalized-medicine industry takes hit from Supreme Court
by Heidi Ledford - 383-384 China, Japan, CERN: Who will host the next LHC?
by Elizabeth Gibney - 385-386 Obama’s science legacy: betting big on biomedical science
by Heidi Ledford - 386-386 Obama’s science legacy: a space race stalls
by Alexandra Witze - 386-387 Obama’s science legacy: uneven progress on scientific integrity
by Richard Monastersky - 387-387 Obama’s science legacy: climate (policy) hots up
by Jeff Tollefson - 388-390 Busting the billion-dollar myth: how to slash the cost of drug development
by Amy Maxmen - 391-393 Expand the frontiers of urban sustainability
by David Wachsmuth & Daniel Aldana Cohen & Hillary Angelo - 394-395 In retrospect: Flowers for Algernon
by Ananyo Bhattacharya - 395-395 Books in brief
by Barbara Kiser - 396-396 Social changes affect water quality too
by Alec Rolston - 396-396 Venezuela's brain drain is accelerating
by Jaime Requena - 396-396 Stop marginalizing rare syndromes
by Svein Olav Kolset - 396-396 Don't let climate crush coral efforts
by Jennifer McGowan & Hugh P. Possingham & Ken Anthony - 396-396 Strengthen China's flood control
by Yang Zhou & Yansui Liu & Wenxiang Wu - 397-397 Alfred G. Knudson (1922–2016)
by Carlo M. Croce - 400-401 Generation soft
by Barbara Mazzolai & Virgilio Mattoli - 401-402 Friendly neighbours feed tumour cells
by Jurre J. Kamphorst & Eyal Gottlieb - 402-404 Signal locked in
by Kimberley C. Snowden & Bart J. Janssen - 404-405 Fleeting glimpse of an elusive element
by Thomas E. Albrecht-Schmitt - 405-406 Memories linked within a window of time
by Howard Eichenbaum - 407-408 Mitotic regulation comes into focus
by David O. Morgan - 408-409 Earth-like planet around Sun's neighbour
by Artie P. Hatzes - 411-418 Early onset of industrial-era warming across the oceans and continents
by Nerilie J. Abram & Helen V. McGregor & Jessica E. Tierney & Michael N. Evans & Nicholas P. McKay & Darrell S. Kaufman - 419-424 Genomic insights into the origin of farming in the ancient Near East
by Iosif Lazaridis & Dani Nadel & Gary Rollefson & Deborah C. Merrett & Nadin Rohland & Swapan Mallick & Daniel Fernandes & Mario Novak & Beatriz Gamarra & Kendra Sirak & Sarah Connell & Kristin Stewardson & Eadaoin Harney & Qiaomei Fu & Gloria Gonzalez-Fortes & Eppie R. Jones & Songül Alpaslan Roodenberg & György Lengyel & Fanny Bocquentin & Boris Gasparian & Janet M. Monge & Michael Gregg & Vered Eshed & Ahuva-Sivan Mizrahi & Christopher Meiklejohn & Fokke Gerritsen & Luminita Bejenaru & Matthias Blüher & Archie Campbell & Gianpiero Cavalleri & David Comas & Philippe Froguel & Edmund Gilbert & Shona M. Kerr & Peter Kovacs & Johannes Krause & Darren McGettigan & Michael Merrigan & D. Andrew Merriwether & Seamus O'Reilly & Martin B. Richards & Ornella Semino & Michel Shamoon-Pour & Gheorghe Stefanescu & Michael Stumvoll & Anke Tönjes & Antonio Torroni & James F. Wilson & Loic Yengo & Nelli A. Hovhannisyan & Nick Patterson & Ron Pinhasi & David Reich - 425-430 Uncovering Earth’s virome
by David Paez-Espino & Emiley A. Eloe-Fadrosh & Georgios A. Pavlopoulos & Alex D. Thomas & Marcel Huntemann & Natalia Mikhailova & Edward Rubin & Natalia N. Ivanova & Nikos C. Kyrpides - 431-436 Molecular basis of APC/C regulation by the spindle assembly checkpoint
by Claudio Alfieri & Leifu Chang & Ziguo Zhang & Jing Yang & Sarah Maslen & Mark Skehel & David Barford - 437-440 A terrestrial planet candidate in a temperate orbit around Proxima Centauri
by Guillem Anglada-Escudé & Pedro J. Amado & John Barnes & Zaira M. Berdiñas & R. Paul Butler & Gavin A. L. Coleman & Ignacio de la Cueva & Stefan Dreizler & Michael Endl & Benjamin Giesers & Sandra V. Jeffers & James S. Jenkins & Hugh R. A. Jones & Marcin Kiraga & Martin Kürster & Marίa J. López-González & Christopher J. Marvin & Nicolás Morales & Julien Morin & Richard P. Nelson & José L. Ortiz & Aviv Ofir & Sijme-Jan Paardekooper & Ansgar Reiners & Eloy Rodríguez & Cristina Rodrίguez-López & Luis F. Sarmiento & John P. Strachan & Yiannis Tsapras & Mikko Tuomi & Mathias Zechmeister - 441-445 Extending the lifetime of a quantum bit with error correction in superconducting circuits
by Nissim Ofek & Andrei Petrenko & Reinier Heeres & Philip Reinhold & Zaki Leghtas & Brian Vlastakis & Yehan Liu & Luigi Frunzio & S. M. Girvin & L. Jiang & Mazyar Mirrahimi & M. H. Devoret & R. J. Schoelkopf - 446-450 Molecular modifiers reveal a mechanism of pathological crystal growth inhibition
by Jihae Chung & Ignacio Granja & Michael G. Taylor & Giannis Mpourmpakis & John R. Asplin & Jeffrey D. Rimer - 451-455 An integrated design and fabrication strategy for entirely soft, autonomous robots
by Michael Wehner & Ryan L. Truby & Daniel J. Fitzgerald & Bobak Mosadegh & George M. Whitesides & Jennifer A. Lewis & Robert J. Wood - 456-459 Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality
by Santiago Soliveres & Fons van der Plas & Peter Manning & Daniel Prati & Martin M. Gossner & Swen C. Renner & Fabian Alt & Hartmut Arndt & Vanessa Baumgartner & Julia Binkenstein & Klaus Birkhofer & Stefan Blaser & Nico Blüthgen & Steffen Boch & Stefan Böhm & Carmen Börschig & Francois Buscot & Tim Diekötter & Johannes Heinze & Norbert Hölzel & Kirsten Jung & Valentin H. Klaus & Till Kleinebecker & Sandra Klemmer & Jochen Krauss & Markus Lange & E. Kathryn Morris & Jörg Müller & Yvonne Oelmann & Jörg Overmann & Esther Pašalić & Matthias C. Rillig & H. Martin Schaefer & Michael Schloter & Barbara Schmitt & Ingo Schöning & Marion Schrumpf & Johannes Sikorski & Stephanie A. Socher & Emily F. Solly & Ilja Sonnemann & Elisabeth Sorkau & Juliane Steckel & Ingolf Steffan-Dewenter & Barbara Stempfhuber & Marco Tschapka & Manfred Türke & Paul C. Venter & Christiane N. Weiner & Wolfgang W. Weisser & Michael Werner & Catrin Westphal & Wolfgang Wilcke & Volkmar Wolters & Tesfaye Wubet & Susanne Wurst & Markus Fischer & Eric Allan - 460-463 The TRPM2 ion channel is required for sensitivity to warmth
by Chun-Hsiang Tan & Peter A. McNaughton - 464-468 The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6
by Alexander Küffer & Asvin K. K. Lakkaraju & Amit Mogha & Sarah C. Petersen & Kristina Airich & Cédric Doucerain & Rajlakshmi Marpakwar & Pamela Bakirci & Assunta Senatore & Arnaud Monnard & Carmen Schiavi & Mario Nuvolone & Bianka Grosshans & Simone Hornemann & Frederic Bassilana & Kelly R. Monk & Adriano Aguzzi - 469-473 DWARF14 is a non-canonical hormone receptor for strigolactone
by Ruifeng Yao & Zhenhua Ming & Liming Yan & Suhua Li & Fei Wang & Sui Ma & Caiting Yu & Mai Yang & Li Chen & Linhai Chen & Yuwen Li & Chun Yan & Di Miao & Zhongyuan Sun & Jianbin Yan & Yuna Sun & Lei Wang & Jinfang Chu & Shilong Fan & Wei He & Haiteng Deng & Fajun Nan & Jiayang Li & Zihe Rao & Zhiyong Lou & Daoxin Xie - 474-478 Vaccine protection against Zika virus from Brazil
by Rafael A. Larocca & Peter Abbink & Jean Pierre S. Peron & Paolo M. de A. Zanotto & M. Justin Iampietro & Alexander Badamchi-Zadeh & Michael Boyd & David Ng’ang’a & Marinela Kirilova & Ramya Nityanandam & Noe B. Mercado & Zhenfeng Li & Edward T. Moseley & Christine A. Bricault & Erica N. Borducchi & Patricia B. Giglio & David Jetton & George Neubauer & Joseph P. Nkolola & Lori F. Maxfield & Rafael A. De La Barrera & Richard G. Jarman & Kenneth H. Eckels & Nelson L. Michael & Stephen J. Thomas & Dan H. Barouch - 479-483 Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
by Cristovão M. Sousa & Douglas E. Biancur & Xiaoxu Wang & Christopher J. Halbrook & Mara H. Sherman & Li Zhang & Daniel Kremer & Rosa F. Hwang & Agnes K. Witkiewicz & Haoqiang Ying & John M. Asara & Ronald M. Evans & Lewis C. Cantley & Costas A. Lyssiotis & Alec C. Kimmelman - 484-487 Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
by A. J. Venkatakrishnan & Xavier Deupi & Guillaume Lebon & Franziska M. Heydenreich & Tilman Flock & Tamara Miljus & Santhanam Balaji & Michel Bouvier & Dmitry B. Veprintsev & Christopher G. Tate & Gebhard F. X. Schertler & M. Madan Babu - 488-488 Retraction Note: Odour receptors and neurons for DEET and new insect repellents
by Pinky Kain & Sean Michael Boyle & Sana Khalid Tharadra & Tom Guda & Christine Pham & Anupama Dahanukar & Anandasankar Ray - 488-488 Erratum: The bacterial DnaA-trio replication origin element specifies single-stranded DNA initiator binding
by Tomas T. Richardson & Omar Harran & Heath Murray - 488-488 Correction: Corrigendum: Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling
by Zinan Zhou & Alan T. Tang & Weng-Yew Wong & Sharika Bamezai & Lauren M. Goddard & Robert Shenkar & Su Zhou & Jisheng Yang & Alexander C. Wright & Matthew Foley & J. Simon C. Arthur & Kevin J. Whitehead & Issam A. Awad & Dean Y. Li & Xiangjian Zheng & Mark L. Kahn - 489-491 Moonlighting: Dip your toes
by Amy Maxmen - 491-491 Trade talk: Binational liaison
by Monya Baker - 494-494 Interdimensional trade benefits
by Brian Trent
August 2016, Volume 536, Issue 7616
- 251-251 Define the Anthropocene in terms of the whole Earth
by Clive Hamilton - 257-258 Mosquito guns and heavy fines: how Cuba kept Zika at bay for so long
by Sara Reardon - 258-259 Artificial black hole creates its own version of Hawking radiation
by Davide Castelvecchi - 260-260 Nobel laureate’s death highlights struggles at Egyptian science hub
by Pakinam Amer & Mohammed Yahia - 260-261 Trump’s border-wall pledge threatens delicate desert ecosystems
by Brian Owens - 261-262 Morphing neutrinos provide clue to antimatter mystery
by Elizabeth Gibney - 263-265 Bottles, bags, ropes and toothbrushes: the struggle to track ocean plastics
by Daniel Cressey - 266-268 The plastics revolution: how chemists are pushing polymers to new limits
by Mark Peplow - 269-270 Rethink how chemical hazards are tested
by John C. Warner & Jennifer K. Ludwig - 271-272 Ethics: Taming our technologies
by Steven Aftergood - 272-273 Q&A: Brenda Keneghan: The polymer conservator
by Elizabeth Gibney - 273-273 Books in brief
by Barbara Kiser - 274-274 Being more open about PhD papers
by Joy Burrough-Boenisch - 274-274 Music calculations out of tune
by Adrian Goldman - 274-274 World's last in vitro fertilization ban falls
by Felipe Mora-Bermúdez - 274-274 Stop vultures from striking aircraft
by Antoni Margalida - 274-274 Royal Society helps guide Brexit science
by Julie Maxton - 276-277 Sixty years of living polymers
by Gary Patterson - 277-278 A deep dive into genetic variation
by Jay Shendure - 278-280 Flipping the sleep switch
by Stephane Dissel & Paul J. Shaw - 280-281 Elusive active site in focus
by Jay A. Labinger - 281-282 Mechanics drives cell differentiation
by Berenika Plusa & Anna-Katerina Hadjantonakis - 282-283 Superconducting electrons go missing
by Jan Zaanen - 285-291 Analysis of protein-coding genetic variation in 60,706 humans
by Monkol Lek & Konrad J. Karczewski & Eric V. Minikel & Kaitlin E. Samocha & Eric Banks & Timothy Fennell & Anne H. O’Donnell-Luria & James S. Ware & Andrew J. Hill & Beryl B. Cummings & Taru Tukiainen & Daniel P. Birnbaum & Jack A. Kosmicki & Laramie E. Duncan & Karol Estrada & Fengmei Zhao & James Zou & Emma Pierce-Hoffman & Joanne Berghout & David N. Cooper & Nicole Deflaux & Mark DePristo & Ron Do & Jason Flannick & Menachem Fromer & Laura Gauthier & Jackie Goldstein & Namrata Gupta & Daniel Howrigan & Adam Kiezun & Mitja I. Kurki & Ami Levy Moonshine & Pradeep Natarajan & Lorena Orozco & Gina M. Peloso & Ryan Poplin & Manuel A. Rivas & Valentin Ruano-Rubio & Samuel A. Rose & Douglas M. Ruderfer & Khalid Shakir & Peter D. Stenson & Christine Stevens & Brett P. Thomas & Grace Tiao & Maria T. Tusie-Luna & Ben Weisburd & Hong-Hee Won & Dongmei Yu & David M. Altshuler & Diego Ardissino & Michael Boehnke & John Danesh & Stacey Donnelly & Roberto Elosua & Jose C. Florez & Stacey B. Gabriel & Gad Getz & Stephen J. Glatt & Christina M. Hultman & Sekar Kathiresan & Markku Laakso & Steven McCarroll & Mark I. McCarthy & Dermot McGovern & Ruth McPherson & Benjamin M. Neale & Aarno Palotie & Shaun M. Purcell & Danish Saleheen & Jeremiah M. Scharf & Pamela Sklar & Patrick F. Sullivan & Jaakko Tuomilehto & Ming T. Tsuang & Hugh C. Watkins & James G. Wilson & Mark J. Daly & Daniel G. MacArthur - 292-297 Circadian neuron feedback controls the Drosophila sleep–activity profile
by Fang Guo & Junwei Yu & Hyung Jae Jung & Katharine C. Abruzzi & Weifei Luo & Leslie C. Griffith & Michael Rosbash - 298-303 Defining the clonal dynamics leading to mouse skin tumour initiation
by Adriana Sánchez-Danés & Edouard Hannezo & Jean-Christophe Larsimont & Mélanie Liagre & Khalil Kass Youssef & Benjamin D. Simons & Cédric Blanpain - 304-308 Capturing a substrate in an activated RING E3/E2–SUMO complex
by Frederick C. Streich Jr & Christopher D. Lima - 309-311 Dependence of the critical temperature in overdoped copper oxides on superfluid density
by I. Božović & X. He & J. Wu & A. T. Bollinger - 312-316 High-efficiency two-dimensional Ruddlesden–Popper perovskite solar cells
by Hsinhan Tsai & Wanyi Nie & Jean-Christophe Blancon & Constantinos C. Stoumpos & Reza Asadpour & Boris Harutyunyan & Amanda J. Neukirch & Rafael Verduzco & Jared J. Crochet & Sergei Tretiak & Laurent Pedesseau & Jacky Even & Muhammad A. Alam & Gautam Gupta & Jun Lou & Pulickel M. Ajayan & Michael J. Bedzyk & Mercouri G. Kanatzidis & Aditya D. Mohite - 317-321 The active site of low-temperature methane hydroxylation in iron-containing zeolites
by Benjamin E. R. Snyder & Pieter Vanelderen & Max L. Bols & Simon D. Hallaert & Lars H. Böttger & Liviu Ungur & Kristine Pierloot & Robert A. Schoonheydt & Bert F. Sels & Edward I. Solomon - 322-325 Metallaphotoredox-catalysed sp3–sp3 cross-coupling of carboxylic acids with alkyl halides
by Craig P. Johnston & Russell T. Smith & Simon Allmendinger & David W. C. MacMillan - 326-328 An early geodynamo driven by exsolution of mantle components from Earth’s core
by James Badro & Julien Siebert & Francis Nimmo - 329-332 Natural courtship song variation caused by an intronic retroelement in an ion channel gene
by Yun Ding & Augusto Berrocal & Tomoko Morita & Kit D. Longden & David L. Stern - 333-337 Operation of a homeostatic sleep switch
by Diogo Pimentel & Jeffrey M. Donlea & Clifford B. Talbot & Seoho M. Song & Alexander J. F. Thurston & Gero Miesenböck - 338-343 A human neurodevelopmental model for Williams syndrome
by Thanathom Chailangkarn & Cleber A. Trujillo & Beatriz C. Freitas & Branka Hrvoj-Mihic & Roberto H. Herai & Diana X. Yu & Timothy T. Brown & Maria C. Marchetto & Cedric Bardy & Lauren McHenry & Lisa Stefanacci & Anna Järvinen & Yvonne M. Searcy & Michelle DeWitt & Wenny Wong & Philip Lai & M. Colin Ard & Kari L. Hanson & Sarah Romero & Bob Jacobs & Anders M. Dale & Li Dai & Julie R. Korenberg & Fred H. Gage & Ursula Bellugi & Eric Halgren & Katerina Semendeferi & Alysson R. Muotri - 344-348 Asymmetric division of contractile domains couples cell positioning and fate specification
by Jean-Léon Maître & Hervé Turlier & Rukshala Illukkumbura & Björn Eismann & Ritsuya Niwayama & François Nédélec & Takashi Hiiragi - 349-353 HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis
by David A. Jacques & William A. McEwan & Laura Hilditch & Amanda J. Price & Greg J. Towers & Leo C. James - 354-358 Structure of mammalian respiratory complex I
by Jiapeng Zhu & Kutti R. Vinothkumar & Judy Hirst - 359-359 Correction: Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
by Yu-Hwa Huang & Chen Zhu & Yasuyuki Kondo & Ana C. Anderson & Amit Gandhi & Andrew Russell & Stephanie K. Dougan & Britt-Sabina Petersen & Espen Melum & Thomas Pertel & Kiera L. Clayton & Monika Raab & Qiang Chen & Nicole Beauchemin & Paul J. Yazaki & Michal Pyzik & Mario A. Ostrowski & Jonathan N. Glickman & Christopher E. Rudd & Hidde L. Ploegh & Andre Franke & Gregory A. Petsko & Vijay K. Kuchroo & Richard S. Blumberg - 360-360 Correction: Corrigendum: Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases
by Dominik A. Herbst & Roman P. Jakob & Franziska Zähringer & Timm Maier - 360-360 Correction: Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1
by Edward T. Chouchani & Lawrence Kazak & Mark P. Jedrychowski & Gina Z. Lu & Brian K. Erickson & John Szpyt & Kerry A. Pierce & Dina Laznik-Bogoslavski & Ramalingam Vetrivelan & Clary B. Clish & Alan J. Robinson & Steve P. Gygi & Bruce M. Spiegelman - 360-360 Correction: Corrigendum: A receptor heteromer mediates the male perception of female attractants in plants
by Tong Wang & Liang Liang & Yong Xue & Peng-Fei Jia & Wei Chen & Meng-Xia Zhang & Ying-Chun Wang & Hong-Ju Li & Wei-Cai Yang - 361-363 Let the structural symphony begin
by Stephen Ornes - 365-366 Work abroad: Visa to visit
by Barbra Rodriguez - 368-368 Legacy admissions
by S. R. Algernon
August 2016, Volume 536, Issue 7615
- 127-127 Steer driverless cars towards full automation
by John Baruch - 133-134 Hopes for revolutionary new LHC particle dashed
by Elizabeth Gibney - 134-135 Glider aims to break world record — and boost climate science
by Declan Butler - 135-135 US agency to lift ban on funding human–animal hybrids
by Sara Reardon - 136-137 Replications, ridicule and a recluse: the controversy over NgAgo gene-editing intensifies
by David Cyranoski - 137-137 Beyond CRISPR: A guide to the many other ways to edit a genome
by Heidi Ledford - 138-138 Plant and animal DNA suggests first Americans took the coastal route
by Ewen Callaway - 139-142 The bandwidth bottleneck that is throttling the Internet
by Jeff Hecht - 143-145 Biodiversity: The ravages of guns, nets and bulldozers
by Sean L. Maxwell & Richard A. Fuller & Thomas M. Brooks & James E. M. Watson - 146-147 Microbiology: Mob rule
by Adrian Woolfson - 147-147 Books in brief
by Barbara Kiser