Content
December 2014, Volume 516, Issue 7531
- 321-323 Scientific method: Defend the integrity of physics
by George Ellis & Joe Silk - 323-325 Infectious disease: Mobilizing Ebola survivors to curb the epidemic
by Joshua M. Epstein & Lauren M. Sauer & Julia Chelen & Erez Hatna & Jon Parker & Richard E. Rothman & Lewis Rubinson - 326-328 In retrospect: Between Pacific Tides
by Aaron Hirsh - 329-329 What football can teach science
by Arturo Sala - 329-329 Prescient words on comets and life
by Milton Wainwright - 329-329 Flood resilience a must for delta cities
by Ruben Dahm - 329-329 Pool resources for protected areas
by Jon Hoekstra & Meg Symington & Chris Weaver - 329-329 Research agency will lose autonomy
by András Váradi & János Kertész - 330-330 Martin L. Perl (1927–2014)
by Valerie Halyo - 332-333 Better chemistry through radicals
by Steven L. Castle - 333-334 Toehold gene switches make big footprints
by Simon Ausländer & Martin Fussenegger - 334-335 How vector mosquitoes beat the heat
by Nora J. Besansky - 336-337 Mind the gaps
by Thomas M. Brooks - 337-338 Two steps for a magnetoelectric switch
by Kathrin Dörr & Andreas Herklotz - 338-339 An RNA-synthesizing machine
by Robert M. Krug - 343-348 Functionalized olefin cross-coupling to construct carbon–carbon bonds
by Julian C. Lo & Jinghan Gui & Yuki Yabe & Chung-Mao Pan & Phil S. Baran - 349-354 An AUTS2–Polycomb complex activates gene expression in the CNS
by Zhonghua Gao & Pedro Lee & James M. Stafford & Melanie von Schimmelmann & Anne Schaefer & Danny Reinberg - 355-360 Structure of influenza A polymerase bound to the viral RNA promoter
by Alexander Pflug & Delphine Guilligay & Stefan Reich & Stephen Cusack - 361-366 Structural insight into cap-snatching and RNA synthesis by influenza polymerase
by Stefan Reich & Delphine Guilligay & Alexander Pflug & Hélène Malet & Imre Berger & Thibaut Crépin & Darren Hart & Thomas Lunardi & Max Nanao & Rob W. H. Ruigrok & Stephen Cusack - 367-369 The exclusion of a significant range of ages in a massive star cluster
by Chengyuan Li & Richard de Grijs & Licai Deng - 370-373 Deterministic switching of ferromagnetism at room temperature using an electric field
by J. T. Heron & J. L. Bosse & Q. He & Y. Gao & M. Trassin & L. Ye & J. D. Clarkson & C. Wang & Jian Liu & S. Salahuddin & D. C. Ralph & D. G. Schlom & J. Íñiguez & B. D. Huey & R. Ramesh - 374-378 Reconstruction and control of a time-dependent two-electron wave packet
by Christian Ott & Andreas Kaldun & Luca Argenti & Philipp Raith & Kristina Meyer & Martin Laux & Yizhu Zhang & Alexander Blättermann & Steffen Hagstotz & Thomas Ding & Robert Heck & Javier Madroñero & Fernando Martín & Thomas Pfeifer - 379-382 The contribution of the Precambrian continental lithosphere to global H2 production
by Barbara Sherwood Lollar & T. C. Onstott & G. Lacrampe-Couloume & C. J. Ballentine - 383-386 Global protected area expansion is compromised by projected land-use and parochialism
by Federico Montesino Pouzols & Tuuli Toivonen & Enrico Di Minin & Aija S. Kukkala & Peter Kullberg & Johanna Kuusterä & Joona Lehtomäki & Henrikki Tenkanen & Peter H. Verburg & Atte Moilanen - 387-390 Signatures of aestivation and migration in Sahelian malaria mosquito populations
by A. Dao & A. S. Yaro & M. Diallo & S. Timbiné & D. L. Huestis & Y. Kassogué & A. I. Traoré & Z. L. Sanogo & D. Samaké & T. Lehmann - 391-394 A relative shift in cloacal location repositions external genitalia in amniote evolution
by Patrick Tschopp & Emma Sherratt & Thomas J. Sanger & Anna C. Groner & Ariel C. Aspiras & Jimmy K. Hu & Olivier Pourquié & Jérôme Gros & Clifford J. Tabin - 395-399 Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
by Thorsten Gnad & Saskia Scheibler & Ivar von Kügelgen & Camilla Scheele & Ana Kilić & Anja Glöde & Linda S. Hoffmann & Laia Reverte-Salisa & Philipp Horn & Samet Mutlu & Ali El-Tayeb & Mathias Kranz & Winnie Deuther-Conrad & Peter Brust & Martin E. Lidell & Matthias J. Betz & Sven Enerbäck & Jürgen Schrader & Gennady G. Yegutkin & Christa E. Müller & Alexander Pfeifer - 400-404 Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
by Kyle W. McCracken & Emily M. Catá & Calyn M. Crawford & Katie L. Sinagoga & Michael Schumacher & Briana E. Rockich & Yu-Hwai Tsai & Christopher N. Mayhew & Jason R. Spence & Yana Zavros & James M. Wells - 405-409 Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells
by Jichang Wang & Gangcai Xie & Manvendra Singh & Avazeh T. Ghanbarian & Tamás Raskó & Attila Szvetnik & Huiqiang Cai & Daniel Besser & Alessandro Prigione & Nina V. Fuchs & Gerald G. Schumann & Wei Chen & Matthew C. Lorincz & Zoltán Ivics & Laurence D. Hurst & Zsuzsanna Izsvák - 410-413 Protein quality control at the inner nuclear membrane
by Anton Khmelinskii & Ewa Blaszczak & Marina Pantazopoulou & Bernd Fischer & Deike J. Omnus & Gaëlle Le Dez & Audrey Brossard & Alexander Gunnarsson & Joseph D. Barry & Matthias Meurer & Daniel Kirrmaier & Charles Boone & Wolfgang Huber & Gwenaël Rabut & Per O. Ljungdahl & Michael Knop - 414-417 Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection
by Mark W. Pellegrino & Amrita M. Nargund & Natalia V. Kirienko & Reba Gillis & Christopher J. Fiorese & Cole M. Haynes - 418-422 Rapid development of broadly influenza neutralizing antibodies through redundant mutations
by Leontios Pappas & Mathilde Foglierini & Luca Piccoli & Nicole L. Kallewaard & Filippo Turrini & Chiara Silacci & Blanca Fernandez-Rodriguez & Gloria Agatic & Isabella Giacchetto-Sasselli & Gabriele Pellicciotta & Federica Sallusto & Qing Zhu & Elisa Vicenzi & Davide Corti & Antonio Lanzavecchia - 423-427 In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
by Danilo Maddalo & Eusebio Manchado & Carla P. Concepcion & Ciro Bonetti & Joana A. Vidigal & Yoon-Chi Han & Paul Ogrodowski & Alessandra Crippa & Natasha Rekhtman & Elisa de Stanchina & Scott W. Lowe & Andrea Ventura - 428-431 Rapid modelling of cooperating genetic events in cancer through somatic genome editing
by Francisco J. Sánchez-Rivera & Thales Papagiannakopoulos & Rodrigo Romero & Tuomas Tammela & Matthew R. Bauer & Arjun Bhutkar & Nikhil S. Joshi & Lakshmipriya Subbaraj & Roderick T. Bronson & Wen Xue & Tyler Jacks - 432-435 Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe
by Takeshi Mizuguchi & Geoffrey Fudenberg & Sameet Mehta & Jon-Matthew Belton & Nitika Taneja & Hernan Diego Folco & Peter FitzGerald & Job Dekker & Leonid Mirny & Jemima Barrowman & Shiv I. S. Grewal - 436-439 R-loops induce repressive chromatin marks over mammalian gene terminators
by Konstantina Skourti-Stathaki & Kinga Kamieniarz-Gdula & Nicholas J. Proudfoot - 440-440 Correction: Corrigendum: Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles
by Susanne Walz & Francesca Lorenzin & Jennifer Morton & Katrin E. Wiese & Björn von Eyss & Steffi Herold & Lukas Rycak & Hélène Dumay-Odelot & Saadia Karim & Marek Bartkuhn & Frederik Roels & Torsten Wüstefeld & Matthias Fischer & Martin Teichmann & Lars Zender & Chia-Lin Wei & Owen Sansom & Elmar Wolf & Martin Eilers - 440-440 Editorial Expression of Concern: Non-adaptive origins of interactome complexity
by Ariel Fernández & Michael Lynch - 441-442 Nurture your online persona
by Peter Fiske - 444-444 The chains of plenty
by S. R. Algernon
December 2014, Volume 516, Issue 7530
- 1-2 Latest anomalocaridid affinities challenged
by Georg Mayer & Christine Martin & Ivo de Sena Oliveira & Franziska Anni Franke & Vladimir Gross - 3-4 Cong et al. reply
by Peiyun Cong & Xiaoya Ma & Xianguang Hou & Gregory D. Edgecombe & Nicholas J. Strausfeld - 145-145 Assess the real cost of research assessment
by Peter M. Atkinson - 147-147 Funders drawn to alternative metrics
by Chris Woolston - 151-152 Tsunami alerts fail to bridge the ‘last mile’
by Alexandra Witze - 153-153 Europe proposes joint Moon trips with Russia
by Elizabeth Gibney - 154-155 Ebola experts seek to expand testing
by Declan Butler - 156-156 Immune cells boost cancer survival from months to years
by Heidi Ledford - 157-157 Microsoft billionaire takes on cell biology
by Ewen Callaway - 158-161 Biodiversity: Life – a status report
by Richard Monastersky - 162-164 Stem cells: The black box of reprogramming
by David Cyranoski - 165-166 Microbiology: Ditch the term pathogen
by Arturo Casadevall & Liise-anne Pirofski - 168-169 In retrospect: Elective Affinities
by Matthew Bell - 169-169 Genetics: Genius on the fly
by Ewen Callaway - 170-170 Biodiversity reports need author rules
by Axel Hochkirch & Philip J. K. McGowan & Jeroen van der Sluijs - 170-170 Several fields still need primates
by Angela Roberts & Trevor Robbins - 170-170 Manage military land for the environment
by Rick Zentelis & David Lindenmayer - 170-170 Europe is failing young researchers
by Thomas Schäfer - 170-170 Engaged cohort good for science
by Katarzyna Kordas & Dara O'Hare & Makaela Jacobs-Pearson - 172-173 A designer's guide to pluripotency
by Jun Wu & Juan Carlos Izpisua Belmonte - 173-174 Breakthrough for protons
by Rohit N. Karnik - 175-176 A beacon for bacterial tubulin
by Elizabeth J. Harry - 176-178 Calcium-activated proteins visualized
by Matt Whorton - 178-179 The virtues of tiling
by Peter Fratzl - 179-180 When wells run dry
by Richard Taylor - 181-191 Catalytic enantioselective synthesis of quaternary carbon stereocentres
by Kyle W. Quasdorf & Larry E. Overman - 192-197 Divergent reprogramming routes lead to alternative stem-cell states
by Peter D. Tonge & Andrew J. Corso & Claudio Monetti & Samer M. I. Hussein & Mira C. Puri & Iacovos P. Michael & Mira Li & Dong-Sung Lee & Jessica C. Mar & Nicole Cloonan & David L. Wood & Maely E. Gauthier & Othmar Korn & Jennifer L. Clancy & Thomas Preiss & Sean M. Grimmond & Jong-Yeon Shin & Jeong-Sun Seo & Christine A. Wells & Ian M. Rogers & Andras Nagy - 198-206 Genome-wide characterization of the routes to pluripotency
by Samer M. I. Hussein & Mira C. Puri & Peter D. Tonge & Marco Benevento & Andrew J. Corso & Jennifer L. Clancy & Rowland Mosbergen & Mira Li & Dong-Sung Lee & Nicole Cloonan & David L. A. Wood & Javier Munoz & Robert Middleton & Othmar Korn & Hardip R. Patel & Carl A. White & Jong-Yeon Shin & Maely E. Gauthier & Kim-Anh Lê Cao & Jong-Il Kim & Jessica C. Mar & Nika Shakiba & William Ritchie & John E. J. Rasko & Sean M. Grimmond & Peter W. Zandstra & Christine A. Wells & Thomas Preiss & Jeong-Sun Seo & Albert J. R. Heck & Ian M. Rogers & Andras Nagy - 207-212 X-ray structure of a calcium-activated TMEM16 lipid scramblase
by Janine D. Brunner & Novandy K. Lim & Stephan Schenck & Alessia Duerst & Raimund Dutzler - 213-218 Structure and insights into the function of a Ca2+-activated Cl− channel
by Veronica Kane Dickson & Leanne Pedi & Stephen B. Long - 219-221 H2D+ observations give an age of at least one million years for a cloud core forming Sun-like stars
by Sandra Brünken & Olli Sipilä & Edward T. Chambers & Jorma Harju & Paola Caselli & Oskar Asvany & Cornelia E. Honingh & Tomasz Kamiński & Karl M. Menten & Jürgen Stutzki & Stephan Schlemmer - 222-226 Ultrasensitive mechanical crack-based sensor inspired by the spider sensory system
by Daeshik Kang & Peter V. Pikhitsa & Yong Whan Choi & Chanseok Lee & Sung Soo Shin & Linfeng Piao & Byeonghak Park & Kahp-Yang Suh & Tae-il Kim & Mansoo Choi - 227-230 Proton transport through one-atom-thick crystals
by S. Hu & M. Lozada-Hidalgo & F. C. Wang & A. Mishchenko & F. Schedin & R. R. Nair & E. W. Hill & D. W. Boukhvalov & M. I. Katsnelson & R. A. W. Dryfe & I. V. Grigorieva & H. A. Wu & A. K. Geim - 231-233 Formation and properties of ice XVI obtained by emptying a type sII clathrate hydrate
by Andrzej Falenty & Thomas C. Hansen & Werner F. Kuhs - 234-237 Isotopic constraints on marine and terrestrial N2O emissions during the last deglaciation
by Adrian Schilt & Edward J. Brook & Thomas K. Bauska & Daniel Baggenstos & Hubertus Fischer & Fortunat Joos & Vasilii V. Petrenko & Hinrich Schaefer & Jochen Schmitt & Jeffrey P. Severinghaus & Renato Spahni & Thomas F. Stocker - 238-241 Cell differentiation and germ–soma separation in Ediacaran animal embryo-like fossils
by Lei Chen & Shuhai Xiao & Ke Pang & Chuanming Zhou & Xunlai Yuan - 242-245 An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons
by Frank M. J. Jacobs & David Greenberg & Ngan Nguyen & Maximilian Haeussler & Adam D. Ewing & Sol Katzman & Benedict Paten & Sofie R. Salama & David Haussler - 246-249 Dietary modulation of the microbiome affects autoinflammatory disease
by John R. Lukens & Prajwal Gurung & Peter Vogel & Gordon R. Johnson & Robert A. Carter & Daniel J. McGoldrick & Srinivasa Rao Bandi & Christopher R. Calabrese & Lieselotte Vande Walle & Mohamed Lamkanfi & Thirumala-Devi Kanneganti - 250-253 Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG
by Parveen Goyal & Petya V. Krasteva & Nani Van Gerven & Francesca Gubellini & Imke Van den Broeck & Anastassia Troupiotis-Tsaïlaki & Wim Jonckheere & Gérard Péhau-Arnaudet & Jerome S. Pinkner & Matthew R. Chapman & Scott J. Hultgren & Stefan Howorka & Rémi Fronzes & Han Remaut - 254-258 Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma
by Jagan R. Muppidi & Roland Schmitz & Jesse A. Green & Wenming Xiao & Adrien B. Larsen & Sterling E. Braun & Jinping An & Ying Xu & Andreas Rosenwald & German Ott & Randy D. Gascoyne & Lisa M. Rimsza & Elias Campo & Elaine S. Jaffe & Jan Delabie & Erlend B. Smeland & Rita M. Braziel & Raymond R. Tubbs & J. R. Cook & Dennis D. Weisenburger & Wing C. Chan & Nagarajan Vaidehi & Louis M. Staudt & Jason G. Cyster - 259-262 MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae
by Aurore Fleurie & Christian Lesterlin & Sylvie Manuse & Chao Zhao & Caroline Cluzel & Jean-Pierre Lavergne & Mirita Franz-Wachtel & Boris Macek & Christophe Combet & Erkin Kuru & Michael S. VanNieuwenhze & Yves V. Brun & David Sherratt & Christophe Grangeasse - 263-266 Programmable RNA recognition and cleavage by CRISPR/Cas9
by Mitchell R. O’Connell & Benjamin L. Oakes & Samuel H. Sternberg & Alexandra East-Seletsky & Matias Kaplan & Jennifer A. Doudna - 267-271 Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation
by Harihar Basnet & Xue B. Su & Yuliang Tan & Jill Meisenhelder & Daria Merkurjev & Kenneth A. Ohgi & Tony Hunter & Lorraine Pillus & Michael G. Rosenfeld - 272-275 Regulation of RNA polymerase II activation by histone acetylation in single living cells
by Timothy J. Stasevich & Yoko Hayashi-Takanaka & Yuko Sato & Kazumitsu Maehara & Yasuyuki Ohkawa & Kumiko Sakata-Sogawa & Makio Tokunaga & Takahiro Nagase & Naohito Nozaki & James G. McNally & Hiroshi Kimura - 276-276 Correction: Corrigendum: Mitochondrial gene replacement in primate offspring and embryonic stem cells
by Masahito Tachibana & Michelle Sparman & Hathaitip Sritanaudomchai & Hong Ma & Lisa Clepper & Joy Woodward & Ying Li & Cathy Ramsey & Olena Kolotushkina & Shoukhrat Mitalipov - 276-276 Correction: Corrigendum: Producing primate embryonic stem cells by somatic cell nuclear transfer
by J. A. Byrne & D. A. Pedersen & L. L. Clepper & M. Nelson & W. G. Sanger & S. Gokhale & D. P. Wolf & S. M. Mitalipov - 276-276 Correction: Corrigendum: Nuclear reprogramming by interphase cytoplasm of two-cell mouse embryos
by Eunju Kang & Guangming Wu & Hong Ma & Ying Li & Rebecca Tippner-Hedges & Masahito Tachibana & Michelle Sparman & Don P. Wolf & Hans R. Schöler & Shoukhrat Mitalipov - 277-279 Ocean biology: Marine dreams
by Chris Woolston - 282-282 Missed message
by Rachel Reddick
December 2014, Volume 516, Issue 7529
- 1-1 Liver cancer
by Lauren Gravitz - 2-3 A preventable cancer
by Lucas Laursen - 4-6 Drug development: Try and try again
by Megan Scudellari - 7-7 Perspective: Time to face the fungal threat
by Felicia Wu - 8-9 Fatty liver disease: The liver labyrinth
by Branwen Morgan - 9-9 Science should keep out of partisan politics
by Daniel Sarewitz - 10-11 Sex differences: Luck of the chromosomes
by Courtney Humphries - 12-13 Vaccines: Taking a shot at protection
by Karen Weintraub - 14-16 Microbiome: The bacterial tightrope
by Katherine Bourzac - 15-16 Positive results spur race for Ebola vaccine
by Ewen Callaway - 16-17 Investigations launched into artificial tracheas
by David Cyranoski - 17-17 Perspective: Incision revision
by Myron Schwartz - 18-19 Rival species recast significance of ‘first bird’
by Ewen Callaway - 20-21 Climate tinkerers thrash out a plan
by Quirin Schiermeier - 21-22 Projects seek hidden effects of cancer drugs
by Heidi Ledford - 24-26 Physics: Quantum computer quest
by Elizabeth Gibney - 28-30 Natural gas: The fracking fallacy
by Mason Inman - 31-33 Climate change: Protect the world's deltas
by Liviu Giosan & James Syvitski & Stefan Constantinescu & John Day - 34-35 Mathematics: Set theory for six-year-olds
by Alex Bellos - 35-35 Books in brief
by Barbara Kiser - 36-36 Robotics: Bottom-up innovation
by Noel Sharkey - 37-37 Conservation: Focus on implementation
by Erik Meijaard & Douglas Sheil & Marcel Cardillo - 37-37 New pasture plants pose weed risk
by Don Driscoll & Jane Catford - 37-37 Conservation: More than inclusivity
by Laura J. Martin & Sara B. Pritchard - 37-37 Conservation: Stop profit trumping all
by Jessica Dempsey & Rosemary Collard & Juanita Sundberg - 37-37 Conservation: Listen to more voices
by David A. Wardle - 38-38 Herman Eisen (1918–2014)
by Lisa Steiner & Hidde Ploegh - 40-41 Autophagy transcribed
by Carmine Settembre & Andrea Ballabio - 41-42 Controls on isotopic gradients in rain
by Katherine H. Freeman - 42-43 A backup for bacteria
by Yao Wang & Julie K. Pfeiffer - 44-45 Stars fight back
by Philip F. Hopkins - 45-46 A molecular knife to dice depression
by Gerhard Schratt - 46-47 Ultrafast imaging takes on a new design
by Brian W. Pogue - 48-49 Professional identity can increase dishonesty
by Marie Claire Villeval - 49-50 The good in fat
by Deborah M. Muoio & Christopher B. Newgard - 51-55 β-catenin mediates stress resilience through Dicer1/microRNA regulation
by Caroline Dias & Jian Feng & Haosheng Sun & Ning yi Shao & Michelle S. Mazei-Robison & Diane Damez-Werno & Kimberly Scobie & Rosemary Bagot & Benoit LaBonté & Efrain Ribeiro & XiaoChuan Liu & Pamela Kennedy & Vincent Vialou & Deveroux Ferguson & Catherine Peña & Erin S. Calipari & Ja Wook Koo & Ezekiell Mouzon & Subroto Ghose & Carol Tamminga & Rachael Neve & Li Shen & Eric J. Nestler - 56-61 Deconstructing transcriptional heterogeneity in pluripotent stem cells
by Roshan M. Kumar & Patrick Cahan & Alex K. Shalek & Rahul Satija & A. Jay DaleyKeyser & Hu Li & Jin Zhang & Keith Pardee & David Gennert & John J. Trombetta & Thomas C. Ferrante & Aviv Regev & George Q. Daley & James J. Collins - 62-67 Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase
by Julia Steuber & Georg Vohl & Marco S. Casutt & Thomas Vorburger & Kay Diederichs & Günter Fritz - 68-70 Stellar feedback as the origin of an extended molecular outflow in a starburst galaxy
by J. E. Geach & R. C. Hickox & A. M. Diamond-Stanic & M. Krips & G. H. Rudnick & C. A. Tremonti & P. H. Sell & A. L. Coil & J. Moustakas - 71-73 Nonlinear lattice dynamics as a basis for enhanced superconductivity in YBa2Cu3O6.5
by R. Mankowsky & A. Subedi & M. Först & S. O. Mariager & M. Chollet & H. T. Lemke & J. S. Robinson & J. M. Glownia & M. P. Minitti & A. Frano & M. Fechner & N. A. Spaldin & T. Loew & B. Keimer & A. Georges & A. Cavalleri - 74-77 Single-shot compressed ultrafast photography at one hundred billion frames per second
by Liang Gao & Jinyang Liang & Chiye Li & Lihong V. Wang - 78-81 Conductive two-dimensional titanium carbide ‘clay’ with high volumetric capacitance
by Michael Ghidiu & Maria R. Lukatskaya & Meng-Qiang Zhao & Yury Gogotsi & Michel W. Barsoum - 82-85 Eastern Pacific tropical cyclones intensified by El Niño delivery of subsurface ocean heat
by F.-F. Jin & J. Boucharel & I.-I. Lin - 86-89 Business culture and dishonesty in the banking industry
by Alain Cohn & Ernst Fehr & Michel André Maréchal - 90-93 Inhibition of cell expansion by rapid ABP1-mediated auxin effect on microtubules
by Xu Chen & Laurie Grandont & Hongjiang Li & Robert Hauschild & Sébastien Paque & Anas Abuzeineh & Hana Rakusová & Eva Benkova & Catherine Perrot-Rechenmann & Jiří Friml - 94-98 An enteric virus can replace the beneficial function of commensal bacteria
by Elisabeth Kernbauer & Yi Ding & Ken Cadwell - 99-103 The ESCRT machinery regulates the secretion and long-range activity of Hedgehog
by Tamás Matusek & Franz Wendler & Sophie Polès & Sandrine Pizette & Gisela D’Angelo & Maximilian Fürthauer & Pascal P. Thérond - 104-107 Centriole amplification by mother and daughter centrioles differs in multiciliated cells
by Adel Al Jord & Anne-Iris Lemaître & Nathalie Delgehyr & Marion Faucourt & Nathalie Spassky & Alice Meunier - 108-111 Transcriptional regulation of autophagy by an FXR–CREB axis
by Sunmi Seok & Ting Fu & Sung-E Choi & Yang Li & Rong Zhu & Subodh Kumar & Xiaoxiao Sun & Gyesoon Yoon & Yup Kang & Wenxuan Zhong & Jian Ma & Byron Kemper & Jongsook Kim Kemper - 112-115 Nutrient-sensing nuclear receptors coordinate autophagy
by Jae Man Lee & Martin Wagner & Rui Xiao & Kang Ho Kim & Dan Feng & Mitchell A. Lazar & David D. Moore - 116-120 TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein
by Sanchita Bhatnagar & Claude Gazin & Lynn Chamberlain & Jianhong Ou & Xiaochun Zhu & Jogender S. Tushir & Ching-Man Virbasius & Ling Lin & Lihua J. Zhu & Narendra Wajapeyee & Michael R. Green - 121-125 Piezo2 is the major transducer of mechanical forces for touch sensation in mice
by Sanjeev S. Ranade & Seung-Hyun Woo & Adrienne E. Dubin & Rabih A. Moshourab & Christiane Wetzel & Matt Petrus & Jayanti Mathur & Valérie Bégay & Bertrand Coste & James Mainquist & A. J. Wilson & Allain G. Francisco & Kritika Reddy & Zhaozhu Qiu & John N. Wood & Gary R. Lewin & Ardem Patapoutian - 126-130 Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel
by Stephen G. Brohawn & Ernest B. Campbell & Roderick MacKinnon - 131-132 The automated lab
by Erika Check Hayden - 133-135 Boosting business
by Kendall Powell - 138-138 Reversal of misfortune
by J. W. Armstrong
November 2014, Volume 515, Issue 7528
- 157-157 Haemophilia
by Herb Brody - 158-159 Born in the blood
by Neil Savage - 160-161 Gene therapy: Genie in a vector
by Julie Gould - 162-164 Clotting factors: Stretching time
by Neil Savage - 165-165 Perspective: The fix is in
by Stephen Pemberton - 166-167 Immunology: Oral solutions
by Elie Dolgin - 168-169 Thrombosis: Balancing act
by Cassandra Willyard - 170-171 Orthopaedics: Joint effort
by Katharine Gammon - 172-173 Animal models: Dogged pursuit
by Emily Sohn - 467-467 Open access is tiring out peer reviewers
by Martijn Arns - 473-474 US–China climate deal raises hopes for Lima talks
by Jeff Tollefson - 474-475 Ocean observatory project hits rough water
by Alexandra Witze - 476-476 US regulators move on thought-controlled prosthetics
by Sara Reardon - 477-477 Clinical-trial rules to improve access to results
by Sara Reardon - 478-478 Confusion over publisher’s pioneering open-data rules
by Richard Van Noorden - 479-479 Key Galapagos research station in trouble
by Aleszu Bajak - 480-482 Publishing: The peer-review scam
by Cat Ferguson & Adam Marcus & Ivan Oransky - 484-486 Nuclear power: Desperately seeking plutonium
by Alexandra Witze - 487-488 Microscopy: Hasten high resolution
by Stephen J. Pennycook & Sergei V. Kalinin - 489-490 Military science: Scientific spoils of war
by Ann Finkbeiner - 490-491 Ornithology: Fowl domination
by Ewen Callaway - 491-491 Climate science: A climate trance
by Richard Van Noorden - 492-492 Rename comet probe after Greek hero
by Len Fisher - 492-492 Can brain training boost cognition?
by David Moreau - 492-492 Ebola: the power of behaviour change
by Sebastian Funk & Gwenan M. Knight & Vincent A. A. Jansen - 492-492 Ebola: models do more than forecast
by Caitlin Rivers - 492-492 Chinese universities: beware cronyism
by Hong-Wei Xiao - 492-492 Chinese universities: gear up for Nobels
by Yi-Ping Chen & Yi-Shan Lin & Yi Zhang - 494-495 El Niño's variable history
by Josephine R. Brown - 495-496 A beast of the southern wild
by Anne Weil - 496-498 Antitumour immunity gets a boost
by Jedd D. Wolchok & Timothy A. Chan - 498-499 Cosmic triangles and black-hole masses
by Martin Elvis - 499-501 Polarize to elongate
by Ulrich Tepass - 501-502 Food choices for health and planet
by Elke Stehfest - 502-503 Tolerance lies in the timing
by Nicholas R. J. Gascoigne - 505-511 Belowground biodiversity and ecosystem functioning
by Richard D. Bardgett & Wim H. van der Putten - 512-517 First cranial remains of a gondwanatherian mammal reveal remarkable mosaicism
by David W. Krause & Simone Hoffmann & John R. Wible & E. Christopher Kirk & Julia A. Schultz & Wighart von Koenigswald & Joseph R. Groenke & James B. Rossie & Patrick M. O’Connor & Erik R. Seiffert & Elizabeth R. Dumont & Waymon L. Holloway & Raymond R. Rogers & Lydia J. Rahantarisoa & Addison D. Kemp & Haingoson Andriamialison - 518-522 Global diets link environmental sustainability and human health
by David Tilman & Michael Clark - 523-527 A positional Toll receptor code directs convergent extension in Drosophila
by Adam C. Paré & Athea Vichas & Christopher T. Fincher & Zachary Mirman & Dene L. Farrell & Avantika Mainieri & Jennifer A. Zallen - 528-530 A dust-parallax distance of 19 megaparsecs to the supermassive black hole in NGC 4151
by Sebastian F. Hönig & Darach Watson & Makoto Kishimoto & Jens Hjorth - 531-534 An impenetrable barrier to ultrarelativistic electrons in the Van Allen radiation belts
by D. N. Baker & A. N. Jaynes & V. C. Hoxie & R. M. Thorne & J. C. Foster & X. Li & J. F. Fennell & J. R. Wygant & S. G. Kanekal & P. J. Erickson & W. Kurth & W. Li & Q. Ma & Q. Schiller & L. Blum & D. M. Malaspina & A. Gerrard & L. J. Lanzerotti - 535-539 Metallization of vanadium dioxide driven by large phonon entropy
by John D. Budai & Jiawang Hong & Michael E. Manley & Eliot D. Specht & Chen W. Li & Jonathan Z. Tischler & Douglas L. Abernathy & Ayman H. Said & Bogdan M. Leu & Lynn A. Boatner & Robert J. McQueeney & Olivier Delaire - 540-544 Passive radiative cooling below ambient air temperature under direct sunlight
by Aaswath P. Raman & Marc Abou Anoma & Linxiao Zhu & Eden Rephaeli & Shanhui Fan - 545-549 Design and fabrication of memory devices based on nanoscale polyoxometalate clusters
by Christoph Busche & Laia Vilà-Nadal & Jun Yan & Haralampos N. Miras & De-Liang Long & Vihar P. Georgiev & Asen Asenov & Rasmus H. Pedersen & Nikolaj Gadegaard & Muhammad M. Mirza & Douglas J. Paul & Josep M. Poblet & Leroy Cronin - 550-553 Evolution and forcing mechanisms of El Niño over the past 21,000 years
by Zhengyu Liu & Zhengyao Lu & Xinyu Wen & B. L. Otto-Bliesner & A. Timmermann & K. M. Cobb - 554-557 Multiplex single-molecule interaction profiling of DNA-barcoded proteins
by Liangcai Gu & Chao Li & John Aach & David E. Hill & Marc Vidal & George M. Church - 558-562 MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
by Thomas Powles & Joseph Paul Eder & Gregg D. Fine & Fadi S. Braiteh & Yohann Loriot & Cristina Cruz & Joaquim Bellmunt & Howard A. Burris & Daniel P. Petrylak & Siew-leng Teng & Xiaodong Shen & Zachary Boyd & Priti S. Hegde & Daniel S. Chen & Nicholas J. Vogelzang - 563-567 Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
by Roy S. Herbst & Jean-Charles Soria & Marcin Kowanetz & Gregg D. Fine & Omid Hamid & Michael S. Gordon & Jeffery A. Sosman & David F. McDermott & John D. Powderly & Scott N. Gettinger & Holbrook E. K. Kohrt & Leora Horn & Donald P. Lawrence & Sandra Rost & Maya Leabman & Yuanyuan Xiao & Ahmad Mokatrin & Hartmut Koeppen & Priti S. Hegde & Ira Mellman & Daniel S. Chen & F. Stephen Hodi - 568-571 PD-1 blockade induces responses by inhibiting adaptive immune resistance
by Paul C. Tumeh & Christina L. Harview & Jennifer H. Yearley & I. Peter Shintaku & Emma J. M. Taylor & Lidia Robert & Bartosz Chmielowski & Marko Spasic & Gina Henry & Voicu Ciobanu & Alisha N. West & Manuel Carmona & Christine Kivork & Elizabeth Seja & Grace Cherry & Antonio J. Gutierrez & Tristan R. Grogan & Christine Mateus & Gorana Tomasic & John A. Glaspy & Ryan O. Emerson & Harlan Robins & Robert H. Pierce & David A. Elashoff & Caroline Robert & Antoni Ribas - 572-576 Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
by Mahesh Yadav & Suchit Jhunjhunwala & Qui T. Phung & Patrick Lupardus & Joshua Tanguay & Stephanie Bumbaca & Christian Franci & Tommy K. Cheung & Jens Fritsche & Toni Weinschenk & Zora Modrusan & Ira Mellman & Jennie R. Lill & Lélia Delamarre - 577-581 Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
by Matthew M. Gubin & Xiuli Zhang & Heiko Schuster & Etienne Caron & Jeffrey P. Ward & Takuro Noguchi & Yulia Ivanova & Jasreet Hundal & Cora D. Arthur & Willem-Jan Krebber & Gwenn E. Mulder & Mireille Toebes & Matthew D. Vesely & Samuel S. K. Lam & Alan J. Korman & James P. Allison & Gordon J. Freeman & Arlene H. Sharpe & Erika L. Pearce & Ton N. Schumacher & Ruedi Aebersold & Hans-Georg Rammensee & Cornelis J. M. Melief & Elaine R. Mardis & William E. Gillanders & Maxim N. Artyomov & Robert D. Schreiber - 582-586 Histone H2A.Z subunit exchange controls consolidation of recent and remote memory
by Iva B. Zovkic & Brynna S. Paulukaitis & Jeremy J. Day & Deepa M. Etikala & J. David Sweatt - 587-590 Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state
by Pedro Crevillén & Hongchun Yang & Xia Cui & Christiaan Greeff & Martin Trick & Qi Qiu & Xiaofeng Cao & Caroline Dean