Content
December 2023, Volume 14, Issue 1
- 1-20 RUFY3 regulates endolysosomes perinuclear positioning, antigen presentation and migration in activated phagocytes
by Rémy Char & Zhuangzhuang Liu & Cédric Jacqueline & Marion Davieau & Maria-Graciela Delgado & Clara Soufflet & Mathieu Fallet & Lionel Chasson & Raphael Chapuy & Voahirana Camosseto & Eva Strock & Rejane Rua & Catarina R. Almeida & Bing Su & Ana-Maria Lennon-Duménil & Beatrice Nal & Antoine Roquilly & Yinming Liang & Stéphane Méresse & Evelina Gatti & Philippe Pierre - 1-20 Self-anticoagulant sponge for whole blood auto-transfusion and its mechanism of coagulation factor inactivation
by Tao Xu & Haifeng Ji & Lin Xu & Shengjun Cheng & Xianda Liu & Yupei Li & Rui Zhong & Weifeng Zhao & Jayachandran N. Kizhakkedathu & Changsheng Zhao - 1-20 TMEM135 links peroxisomes to the regulation of brown fat mitochondrial fission and energy homeostasis
by Donghua Hu & Min Tan & Dongliang Lu & Brian Kleiboeker & Xuejing Liu & Hongsuk Park & Alexxai V. Kravitz & Kooresh I. Shoghi & Yu-Hua Tseng & Babak Razani & Akihiro Ikeda & Irfan J. Lodhi - 1-20 H3.1K27me1 loss confers Arabidopsis resistance to Geminivirus by sequestering DNA repair proteins onto host genome
by Zhen Wang & Claudia M. Castillo-González & Changjiang Zhao & Chun-Yip Tong & Changhao Li & Songxiao Zhong & Zhiyang Liu & Kaili Xie & Jiaying Zhu & Zhongshou Wu & Xu Peng & Yannick Jacob & Scott D. Michaels & Steven E. Jacobsen & Xiuren Zhang - 1-20 Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation
by Moises Freitas-Andrade & Cesar H. Comin & Peter Dyken & Julie Ouellette & Joanna Raman-Nair & Nicole Blakeley & Qing Yan Liu & Sonia Leclerc & Youlian Pan & Ziying Liu & Micaël Carrier & Karan Thakur & Alexandre Savard & Gareth M. Rurak & Marie-Ève Tremblay & Natalina Salmaso & Luciano da F. Costa & Gianfilippo Coppola & Baptiste Lacoste - 1-20 CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons
by Gong-Her Wu & Charlene Smith-Geater & Jesús G. Galaz-Montoya & Yingli Gu & Sanket R. Gupte & Ranen Aviner & Patrick G. Mitchell & Joy Hsu & Ricardo Miramontes & Keona Q. Wang & Nicolette R. Geller & Cathy Hou & Cristina Danita & Lydia-Marie Joubert & Michael F. Schmid & Serena Yeung & Judith Frydman & William Mobley & Chengbiao Wu & Leslie M. Thompson & Wah Chiu - 1-20 Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen
by Katharine M. Wright & Sarah R. DiNapoli & Michelle S. Miller & P. Aitana Azurmendi & Xiaowei Zhao & Zhiheng Yu & Mayukh Chakrabarti & WuXian Shi & Jacqueline Douglass & Michael S. Hwang & Emily Han-Chung Hsiue & Brian J. Mog & Alexander H. Pearlman & Suman Paul & Maximilian F. Konig & Drew M. Pardoll & Chetan Bettegowda & Nickolas Papadopoulos & Kenneth W. Kinzler & Bert Vogelstein & Shibin Zhou & Sandra B. Gabelli - 1-20 The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion
by Laura Onuchic & Valeria Padovano & Giorgia Schena & Vanathy Rajendran & Ke Dong & Xiaojian Shi & Raj Pandya & Victoria Rai & Nikolay P. Gresko & Omair Ahmed & TuKiet T. Lam & Weiwei Wang & Hongying Shen & Stefan Somlo & Michael J. Caplan - 1-20 Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome
by Luis O. Romero & Rebeca Caires & A. Kaitlyn Victor & Juanma Ramirez & Francisco J. Sierra-Valdez & Patrick Walsh & Vincent Truong & Jungsoo Lee & Ugo Mayor & Lawrence T. Reiter & Valeria Vásquez & Julio F. Cordero-Morales - 1-20 Stress-induced metabolic exchanges between complementary bacterial types underly a dynamic mechanism of inter-species stress resistance
by Kapil Amarnath & Avaneesh V. Narla & Sammy Pontrelli & Jiajia Dong & Jack Reddan & Brian R. Taylor & Tolga Caglar & Julia Schwartzman & Uwe Sauer & Otto X. Cordero & Terence Hwa - 1-20 Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer
by Mary C. Bedard & Tafadzwa Chihanga & Adrean Carlile & Robert Jackson & Marion G. Brusadelli & Denis Lee & Andrew VonHandorf & Mark Rochman & Phillip J. Dexheimer & Jeffrey Chalmers & Gerard Nuovo & Maria Lehn & David E. J. Williams & Aditi Kulkarni & Molly Carey & Amanda Jackson & Caroline Billingsley & Alice Tang & Chad Zender & Yash Patil & Trisha M. Wise-Draper & Thomas J. Herzog & Robert L. Ferris & Ady Kendler & Bruce J. Aronow & Matthew Kofron & Marc E. Rothenberg & Matthew T. Weirauch & Koenraad Doorslaer & Kathryn A. Wikenheiser-Brokamp & Paul F. Lambert & Mike Adam & S. Steven Potter & Susanne I. Wells - 1-20 Reprogramming systemic and local immune function to empower immunotherapy against glioblastoma
by Songlei Zhou & Yukun Huang & Yu Chen & Yipu Liu & Laozhi Xie & Yang You & Shiqiang Tong & Jianpei Xu & Gan Jiang & Qingxiang Song & Ni Mei & Fenfen Ma & Xiaoling Gao & Hongzhuan Chen & Jun Chen - 1-20 Quality control of protein synthesis in the early elongation stage
by Asuteka Nagao & Yui Nakanishi & Yutaro Yamaguchi & Yoshifumi Mishina & Minami Karoji & Takafumi Toya & Tomoya Fujita & Shintaro Iwasaki & Kenjyo Miyauchi & Yuriko Sakaguchi & Tsutomu Suzuki - 1-20 Zika virus remodelled ER membranes contain proviral factors involved in redox and methylation pathways
by Solène Denolly & Alexey Stukalov & Uladzimir Barayeu & Alina N. Rosinski & Paraskevi Kritsiligkou & Sebastian Joecks & Tobias P. Dick & Andreas Pichlmair & Ralf Bartenschlager - 1-20 A systematic study of key elements underlying molecular property prediction
by Jianyuan Deng & Zhibo Yang & Hehe Wang & Iwao Ojima & Dimitris Samaras & Fusheng Wang - 1-20 Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia
by Hope Mumme & Beena E. Thomas & Swati S. Bhasin & Upaasana Krishnan & Bhakti Dwivedi & Pruthvi Perumalla & Debasree Sarkar & Gulay B. Ulukaya & Himalee S. Sabnis & Sunita I. Park & Deborah DeRyckere & Sunil S. Raikar & Melinda Pauly & Ryan J. Summers & Sharon M. Castellino & Daniel S. Wechsler & Christopher C. Porter & Douglas K. Graham & Manoj Bhasin - 1-20 RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis
by Xiao Han & Lijuan Liu & Saihua Huang & Wenfeng Xiao & Yajing Gao & Weitao Zhou & Caiyan Zhang & Hongmei Zheng & Lan Yang & Xueru Xie & Qiuyan Liang & Zikun Tu & Hongmiao Yu & Jinrong Fu & Libo Wang & Xiaobo Zhang & Liling Qian & Yufeng Zhou - 1-20 Whole-genome screens reveal regulators of differentiation state and context-dependent migration in human neutrophils
by Nathan M. Belliveau & Matthew J. Footer & Emel Akdoǧan & Aaron P. Loon & Sean R. Collins & Julie A. Theriot - 1-20 Visualization of accessible cholesterol using a GRAM domain-based biosensor
by Dylan Hong Zheng Koh & Tomoki Naito & Minyoung Na & Yee Jie Yeap & Pritisha Rozario & Franklin L. Zhong & Kah-Leong Lim & Yasunori Saheki - 1-20 Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development
by Christopher Bono & Yang Liu & Alexander Ferrena & Aneesa Valentine & Deyou Zheng & Bernice E. Morrow - 1-20 Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants
by Tomokazu Tamura & Jumpei Ito & Keiya Uriu & Jiri Zahradnik & Izumi Kida & Yuki Anraku & Hesham Nasser & Maya Shofa & Yoshitaka Oda & Spyros Lytras & Naganori Nao & Yukari Itakura & Sayaka Deguchi & Rigel Suzuki & Lei Wang & MST Monira Begum & Shunsuke Kita & Hisano Yajima & Jiei Sasaki & Kaori Sasaki-Tabata & Ryo Shimizu & Masumi Tsuda & Yusuke Kosugi & Shigeru Fujita & Lin Pan & Daniel Sauter & Kumiko Yoshimatsu & Saori Suzuki & Hiroyuki Asakura & Mami Nagashima & Kenji Sadamasu & Kazuhisa Yoshimura & Yuki Yamamoto & Tetsuharu Nagamoto & Gideon Schreiber & Katsumi Maenaka & Takao Hashiguchi & Terumasa Ikeda & Takasuke Fukuhara & Akatsuki Saito & Shinya Tanaka & Keita Matsuno & Kazuo Takayama & Kei Sato - 1-20 The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG
by Eitan Kugler & Shreyas Madiwale & Darren Yong & Julie A. I. Thoms & Yehudit Birger & David B. Sykes & Johannes Schmoellerl & Aneta Drakul & Valdemar Priebe & Muhammad Yassin & Nasma Aqaqe & Avigail Rein & Hila Fishman & Ifat Geron & Chun-Wei Chen & Brian Raught & Qiao Liu & Heather Ogana & Elisabeth Liedke & Jean-Pierre Bourquin & Johannes Zuber & Michael Milyavsky & John Pimanda & Gilbert G. Privé & Shai Izraeli - 1-20 Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex
by Yina Wei & Anirban Nandi & Xiaoxuan Jia & Joshua H. Siegle & Daniel Denman & Soo Yeun Lee & Anatoly Buchin & Werner Geit & Clayton P. Mosher & Shawn Olsen & Costas A. Anastassiou - 1-20 Elevated pre-mRNA 3′ end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation
by Yange Cui & Luyang Wang & Qingbao Ding & Jihae Shin & Joel Cassel & Qin Liu & Joseph M. Salvino & Bin Tian - 1-20 Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
by Marc P. Forrest & Marc Dos Santos & Nicolas H. Piguel & Yi-Zhi Wang & Nicole A. Hawkins & Vikram A. Bagchi & Leonardo E. Dionisio & Sehyoun Yoon & Dina Simkin & Maria Dolores Martin-de-Saavedra & Ruoqi Gao & Katherine E. Horan & Alfred L. George & Mark S. LeDoux & Jennifer A. Kearney & Jeffrey N. Savas & Peter Penzes - 1-20 The transcription factor Zeb1 controls homeostasis and function of type 1 conventional dendritic cells
by Yan Wang & Quan Zhang & Tingting He & Yechen Wang & Tianqi Lu & Zengge Wang & Yiyi Wang & Shen Lin & Kang Yang & Xinming Wang & Jun Xie & Ying Zhou & Yazhen Hong & Wen-Hsien Liu & Kairui Mao & Shih-Chin Cheng & Xin Chen & Qiyuan Li & Nengming Xiao - 1-20 BICD2 phosphorylation regulates dynein function and centrosome separation in G2 and M
by Núria Gallisà-Suñé & Paula Sànchez-Fernàndez-de-Landa & Fabian Zimmermann & Marina Serna & Laura Regué & Joel Paz & Oscar Llorca & Jens Lüders & Joan Roig - 1-20 Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis
by Yu Muta & Juan F. Linares & Anxo Martinez-Ordoñez & Angeles Duran & Tania Cid-Diaz & Hiroto Kinoshita & Xiao Zhang & Qixiu Han & Yuki Nakanishi & Naoko Nakanishi & Thekla Cordes & Gurpreet K. Arora & Marc Ruiz-Martinez & Miguel Reina-Campos & Hiroaki Kasashima & Masakazu Yashiro & Kiyoshi Maeda & Ana Albaladejo-Gonzalez & Daniel Torres-Moreno & José García-Solano & Pablo Conesa-Zamora & Giorgio Inghirami & Christian M. Metallo & Timothy F. Osborne & Maria T. Diaz-Meco & Jorge Moscat - 1-20 Catch bond models may explain how force amplifies TCR signaling and antigen discrimination
by Hyun-Kyu Choi & Peiwen Cong & Chenghao Ge & Aswin Natarajan & Baoyu Liu & Yong Zhang & Kaitao Li & Muaz Nik Rushdi & Wei Chen & Jizhong Lou & Michelle Krogsgaard & Cheng Zhu - 1-20 A click chemistry-mediated all-peptide cell printing hydrogel platform for diabetic wound healing
by Jinjian Huang & Rong Yang & Jiao Jiao & Ze Li & Penghui Wang & Ye Liu & Sicheng Li & Canwen Chen & Zongan Li & Guiwen Qu & Kang Chen & Xiuwen Wu & Bo Chi & Jianan Ren - 1-20 Self assembling nanoparticle enzyme clusters provide access to substrate channeling in multienzymatic cascades
by Joyce C. Breger & James N. Vranish & Eunkeu Oh & Michael H. Stewart & Kimihiro Susumu & Guillermo Lasarte-Aragonés & Gregory A. Ellis & Scott A. Walper & Sebastián A. Díaz & Shelby L. Hooe & William P. Klein & Meghna Thakur & Mario G. Ancona & Igor L. Medintz - 1-20 Signal-noise metrics for RNA binding protein identification reveal broad spectrum protein-RNA interaction frequencies and dynamics
by JohnCarlo Kristofich & Christopher V. Nicchitta - 1-20 Photostimulation of brain lymphatics in male newborn and adult rodents for therapy of intraventricular hemorrhage
by Dongyu Li & Shaojun Liu & Tingting Yu & Zhang Liu & Silin Sun & Denis Bragin & Alexander Shirokov & Nikita Navolokin & Olga Bragina & Zhengwu Hu & Jürgen Kurths & Ivan Fedosov & Inna Blokhina & Alexander Dubrovski & Alexander Khorovodov & Andrey Terskov & Maria Tzoy & Oxana Semyachkina-Glushkovskaya & Dan Zhu - 1-20 MYH10 activation rescues contractile defects in arrhythmogenic cardiomyopathy (ACM)
by Nieves García-Quintáns & Silvia Sacristán & Cristina Márquez-López & Cristina Sánchez-Ramos & Fernando Martinez-de-Benito & David Siniscalco & Andrés González-Guerra & Emilio Camafeita & Marta Roche-Molina & Mariya Lytvyn & David Morera & María I. Guillen & María A. Sanguino & David Sanz-Rosa & Daniel Martín-Pérez & Ricardo Garcia & Juan A. Bernal - 1-20 Nanomedicine-based co-delivery of a calcium channel inhibitor and a small molecule targeting CD47 for lung cancer immunotherapy
by Yuedong Guo & Qunqun Bao & Ping Hu & Jianlin Shi - 1-20 Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
by Max Adrian & Martin Weber & Ming-Chi Tsai & Caspar Glock & Olga I. Kahn & Lilian Phu & Tommy K. Cheung & William J. Meilandt & Christopher M. Rose & Casper C. Hoogenraad - 1-20 Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats
by Haobo Han & Jiakai Xing & Wenqi Chen & Jiaxin Jia & Quanshun Li - 1-20 A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection
by Joana Sá-Pessoa & Sara López-Montesino & Kornelia Przybyszewska & Isabel Rodríguez-Escudero & Helina Marshall & Adelia Ova & Gunnar N. Schroeder & Peter Barabas & María Molina & Tim Curtis & Víctor J. Cid & José A. Bengoechea - 1-20 In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy
by Wenquan Ou & Samantha Stewart & Alisa White & Elyahb A. Kwizera & Jiangsheng Xu & Yuanzhang Fang & James G. Shamul & Changqing Xie & Suliat Nurudeen & Nikki P. Tirada & Xiongbin Lu & Katherine H. R. Tkaczuk & Xiaoming He - 1-20 Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites
by Alexander Y. G. Yip & Olivia G. King & Oleksii Omelchenko & Sanjana Kurkimat & Victoria Horrocks & Phoebe Mostyn & Nathan Danckert & Rohma Ghani & Giovanni Satta & Elita Jauneikaite & Frances J. Davies & Thomas B. Clarke & Benjamin H. Mullish & Julian R. Marchesi & Julie A. K. McDonald - 1-20 Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant
by Jumpei Ito & Rigel Suzuki & Keiya Uriu & Yukari Itakura & Jiri Zahradnik & Kanako Terakado Kimura & Sayaka Deguchi & Lei Wang & Spyros Lytras & Tomokazu Tamura & Izumi Kida & Hesham Nasser & Maya Shofa & Mst Monira Begum & Masumi Tsuda & Yoshitaka Oda & Tateki Suzuki & Jiei Sasaki & Kaori Sasaki-Tabata & Shigeru Fujita & Kumiko Yoshimatsu & Hayato Ito & Naganori Nao & Hiroyuki Asakura & Mami Nagashima & Kenji Sadamasu & Kazuhisa Yoshimura & Yuki Yamamoto & Tetsuharu Nagamoto & Jin Kuramochi & Gideon Schreiber & Akatsuki Saito & Keita Matsuno & Kazuo Takayama & Takao Hashiguchi & Shinya Tanaka & Takasuke Fukuhara & Terumasa Ikeda & Kei Sato - 1-20 Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels
by Michaela M. Novakovic & Kirill S. Korshunov & Rogan A. Grant & Megan E. Martin & Hiam A. Valencia & G. R. Scott Budinger & Jelena Radulovic & Murali Prakriya - 1-20 Endothelial discoidin domain receptor 1 senses flow to modulate YAP activation
by Jiayu Liu & Chuanrong Zhao & Xue Xiao & Aohan Li & Yueqi Liu & Jianan Zhao & Linwei Fan & Zhenhui Liang & Wei Pang & Weijuan Yao & Wei Li & Jing Zhou - 1-20 Specific heterozygous variants in MGP lead to endoplasmic reticulum stress and cause spondyloepiphyseal dysplasia
by Ophélie Gourgas & Gabrielle Lemire & Alison J. Eaton & Sultanah Alshahrani & Angela L. Duker & Jingjing Li & Ricki S. Carroll & Stuart Mackenzie & Sarah M. Nikkel & Michael B. Bober & Kym M. Boycott & Monzur Murshed - 1-20 Behavioral decomposition reveals rich encoding structure employed across neocortex in rats
by Bartul Mimica & Tuçe Tombaz & Claudia Battistin & Jingyi Guo Fuglstad & Benjamin A. Dunn & Jonathan R. Whitlock - 1-20 URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers
by Zhiwen Ding & Yufei Pan & Taiyu Shang & Tianyi Jiang & Yunkai Lin & Chun Yang & Shujie Pang & Xiaowen Cui & Yixiu Wang & Xiao fan Feng & Mengyou Xu & Mengmiao Pei & Yibin Chen & Xin Li & Jin Ding & Yexiong Tan & Hongyang Wang & Liwei Dong & Lu Wang - 1-20 Revealing hidden patterns in deep neural network feature space continuum via manifold learning
by Md Tauhidul Islam & Zixia Zhou & Hongyi Ren & Masoud Badiei Khuzani & Daniel Kapp & James Zou & Lu Tian & Joseph C. Liao & Lei Xing - 1-20 TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation
by Yu-Hsuan Chen & Han-Hsiun Chen & Won-Jing Wang & Hsin-Yi Chen & Wei-Syun Huang & Chien-Han Kao & Sin-Rong Lee & Nai Yang Yeat & Ruei-Liang Yan & Shu-Jou Chan & Kuen-Phon Wu & Ruey-Hwa Chen - 1-20 Adult stem cell activity in naked mole rats for long-term tissue maintenance
by Shamir Montazid & Sheila Bandyopadhyay & Daniel W. Hart & Nan Gao & Brian Johnson & Sri G. Thrumurthy & Dustin J. Penn & Bettina Wernisch & Mukesh Bansal & Philipp M. Altrock & Fabian Rost & Patrycja Gazinska & Piotr Ziolkowski & Bu’Hussain Hayee & Yue Liu & Jiangmeng Han & Annamaria Tessitore & Jana Koth & Walter F. Bodmer & James E. East & Nigel C. Bennett & Ian Tomlinson & Shazia Irshad - 1-20 Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton
by Madison L. Doolittle & Dominik Saul & Japneet Kaur & Jennifer L. Rowsey & Stephanie J. Vos & Kevin D. Pavelko & Joshua N. Farr & David G. Monroe & Sundeep Khosla - 1-20 TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress
by Marika K. Kucińska & Juliette Fedry & Carmela Galli & Diego Morone & Andrea Raimondi & Tatiana Soldà & Friedrich Förster & Maurizio Molinari - 1-20 Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex
by Yilun Sun & Simone A. Baechler & Xiaohu Zhang & Suresh Kumar & Valentina M. Factor & Yasuhiro Arakawa & Cindy H. Chau & Kanako Okamoto & Anup Parikh & Bob Walker & Yijun P. Su & Jiji Chen & Tabitha Ting & Shar-yin N. Huang & Erin Beck & Zina Itkin & Crystal McKnight & Changqing Xie & Nitin Roper & Deepak Nijhawan & William Douglas Figg & Paul S. Meltzer & James C. Yang & Craig J. Thomas & Yves Pommier - 1-20 Rab41-mediated ESCRT machinery repairs membrane rupture by a bacterial toxin in xenophagy
by Takashi Nozawa & Hirotaka Toh & Junpei Iibushi & Kohei Kogai & Atsuko Minowa-Nozawa & Junko Satoh & Shinji Ito & Kazunori Murase & Ichiro Nakagawa - 1-20 Four-dimensional trapped ion mobility spectrometry lipidomics for high throughput clinical profiling of human blood samples
by Raissa Lerner & Dhanwin Baker & Claudia Schwitter & Sarah Neuhaus & Tony Hauptmann & Julia M. Post & Stefan Kramer & Laura Bindila - 1-20 SEMA6A drives GnRH neuron-dependent puberty onset by tuning median eminence vascular permeability
by Antonella Lettieri & Roberto Oleari & Marleen Hester Munkhof & Eljo Yvette Battum & Marieke Geerte Verhagen & Carlotta Tacconi & Marco Spreafico & Alyssa Julia Jennifer Paganoni & Roberta Azzarelli & Valentina Andre’ & Federica Amoruso & Luca Palazzolo & Ivano Eberini & Leo Dunkel & Sasha Rose Howard & Alessandro Fantin & Ronald Jeroen Pasterkamp & Anna Cariboni - 1-20 Dynamic and stable hippocampal representations of social identity and reward expectation support associative social memory in male mice
by Eunji Kong & Kyu-Hee Lee & Jongrok Do & Pilhan Kim & Doyun Lee - 1-20 Zika virus prM protein contains cholesterol binding motifs required for virus entry and assembly
by Sarah Goellner & Giray Enkavi & Vibhu Prasad & Solène Denolly & Sungmin Eu & Giulia Mizzon & Leander Witte & Waldemar Kulig & Zina M. Uckeley & Teresa M. Lavacca & Uta Haselmann & Pierre-Yves Lozach & Britta Brügger & Ilpo Vattulainen & Ralf Bartenschlager - 1-20 A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs
by Jing Wang & Ramon Ocadiz-Ruiz & Matthew S. Hall & Grace G. Bushnell & Sophia M. Orbach & Joseph T. Decker & Ravi M. Raghani & Yining Zhang & Aaron H. Morris & Jacqueline S. Jeruss & Lonnie D. Shea - 1-20 WHIM Syndrome-linked CXCR4 mutations drive osteoporosis
by Adrienne Anginot & Julie Nguyen & Zeina Abou Nader & Vincent Rondeau & Amélie Bonaud & Maria Kalogeraki & Antoine Boutin & Julia P. Lemos & Valeria Bisio & Joyce Koenen & Lea Hanna Doumit Sakr & Amandine Picart & Amélie Coudert & Sylvain Provot & Nicolas Dulphy & Michel Aurrand-Lions & Stéphane J. C. Mancini & Gwendal Lazennec & David H. McDermott & Fabien Guidez & Claudine Blin-Wakkach & Philip M. Murphy & Martine Cohen-Solal & Marion Espéli & Matthieu Rouleau & Karl Balabanian - 1-20 FAM3A reshapes VSMC fate specification in abdominal aortic aneurysm by regulating KLF4 ubiquitination
by Chuxiang Lei & Haoxuan Kan & Xiangyu Xian & Wenlin Chen & Wenxuan Xiang & Xiaohong Song & Jianqiang Wu & Dan Yang & Yuehong Zheng - 1-20 Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target
by Marcos Georgiades & Alexandros Alampounti & Jason Somers & Matthew P. Su & David A. Ellis & Judit Bagi & Daniela Terrazas-Duque & Scott Tytheridge & Watson Ntabaliba & Sarah Moore & Joerg T. Albert & Marta Andrés - 1-20 Genomic and microenvironmental heterogeneity shaping epithelial-to-mesenchymal trajectories in cancer
by Guidantonio Malagoli Tagliazucchi & Anna J. Wiecek & Eloise Withnell & Maria Secrier - 1-20 Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs
by Praveen Weeratunga & Laura Denney & Joshua A. Bull & Emmanouela Repapi & Martin Sergeant & Rachel Etherington & Chaitanya Vuppussetty & Gareth D. H. Turner & Colin Clelland & Jeongmin Woo & Amy Cross & Fadi Issa & Carlos Eduardo Andrea & Ignacio Melero Bermejo & David Sims & Simon McGowan & Yasemin-Xiomara Zurke & David J. Ahern & Eddie C. Gamez & Justin Whalley & Duncan Richards & Paul Klenerman & Claudia Monaco & Irina A. Udalova & Tao Dong & Agne Antanaviciute & Graham Ogg & Julian C. Knight & Helen M. Byrne & Stephen Taylor & Ling-Pei Ho - 1-20 Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance
by Daniel J. Fazakerley & Julian van Gerwen & Kristen C. Cooke & Xiaowen Duan & Elise J. Needham & Alexis Díaz-Vegas & Søren Madsen & Dougall M. Norris & Amber S. Shun-Shion & James R. Krycer & James G. Burchfield & Pengyi Yang & Mark R. Wade & Joseph T. Brozinick & David E. James & Sean J. Humphrey - 1-20 Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization
by Toshiharu Onodera & May-Yun Wang & Joseph M. Rutkowski & Stanislaw Deja & Shiuhwei Chen & Michael S. Balzer & Dae-Seok Kim & Xuenan Sun & Yu A. An & Bianca C. Field & Charlotte Lee & Ei-ichi Matsuo & Monika Mizerska & Ina Sanjana & Naoto Fujiwara & Christine M. Kusminski & Ruth Gordillo & Laurent Gautron & Denise K. Marciano & Ming Chang Hu & Shawn C. Burgess & Katalin Susztak & Orson W. Moe & Philipp E. Scherer - 1-20 MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain
by Dustin C. Becht & Brianna J. Klein & Akinori Kanai & Suk Min Jang & Khan L. Cox & Bing-Rui Zhou & Sabrina K. Phanor & Yi Zhang & Ruo-Wen Chen & Christopher C. Ebmeier & Catherine Lachance & Maxime Galloy & Amelie Fradet-Turcotte & Martha L. Bulyk & Yawen Bai & Michael G. Poirier & Jacques Côté & Akihiko Yokoyama & Tatiana G. Kutateladze - 1-20 Engineered hypermutation adapts cyanobacterial photosynthesis to combined high light and high temperature stress
by Huili Sun & Guodong Luan & Yifan Ma & Wenjing Lou & Rongze Chen & Dandan Feng & Shanshan Zhang & Jiahui Sun & Xuefeng Lu - 1-20 A non-canonical striatopallidal Go pathway that supports motor control
by Marie A. Labouesse & Arturo Torres-Herraez & Muhammad O. Chohan & Joseph M. Villarin & Julia Greenwald & Xiaoxiao Sun & Mysarah Zahran & Alice Tang & Sherry Lam & Jeremy Veenstra-VanderWeele & Clay O. Lacefield & Jordi Bonaventura & Michael Michaelides & C. Savio Chan & Ofer Yizhar & Christoph Kellendonk - 1-20 The RNA-binding protein landscapes differ between mammalian organs and cultured cells
by Joel I. Perez-Perri & Dunja Ferring-Appel & Ina Huppertz & Thomas Schwarzl & Sudeep Sahadevan & Frank Stein & Mandy Rettel & Bruno Galy & Matthias W. Hentze - 1-20 Intranasal mask for protecting the respiratory tract against viral aerosols
by Xiaoming Hu & Shuang Wang & Shaotong Fu & Meng Qin & Chengliang Lyu & Zhaowen Ding & Yan Wang & Yishu Wang & Dongshu Wang & Li Zhu & Tao Jiang & Jing Sun & Hui Ding & Jie Wu & Lingqian Chang & Yimin Cui & Xiaocong Pang & Youchun Wang & Weijin Huang & Peidong Yang & Limin Wang & Guanghui Ma & Wei Wei - 1-20 Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia
by Yong Hu & Liu Liu & Yong Chen & Xiaohui Zhang & Haifeng Zhou & Sheng Hu & Xu Li & Meixin Li & Juanjuan Li & Siyuan Cheng & Yong Liu & Yancheng Xu & Wei Yan - 1-20 The unprecedented Pacific Northwest heatwave of June 2021
by Rachel H. White & Sam Anderson & James F. Booth & Ginni Braich & Christina Draeger & Cuiyi Fei & Christopher D. G. Harley & Sarah B. Henderson & Matthias Jakob & Carie-Ann Lau & Lualawi Mareshet Admasu & Veeshan Narinesingh & Christopher Rodell & Eliott Roocroft & Kate R. Weinberger & Greg West - 1-20 Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
by Hyoseon Oh & Suho Lee & Yusang Oh & Seongbin Kim & Young Seo Kim & Yeji Yang & Woochul Choi & Ye-Eun Yoo & Heejin Cho & Seungjoon Lee & Esther Yang & Wuhyun Koh & Woojin Won & Ryunhee Kim & C. Justin Lee & Hyun Kim & Hyojin Kang & Jin Young Kim & Taeyun Ku & Se-Bum Paik & Eunjoon Kim - 1-20 Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response
by Pradeep Ramalingam & Michael C. Gutkin & Michael G. Poulos & Taylor Tillery & Chelsea Doughty & Agatha Winiarski & Ana G. Freire & Shahin Rafii & David Redmond & Jason M. Butler - 1-20 Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis
by Céline Ortega-Ferreira & Perrine Soret & Gautier Robin & Silvia Speca & Sandra Hubert & Marianne Le Gall & Emiko Desvaux & Manel Jendoubi & Julie Saint-Paul & Loubna Chadli & Agnès Chomel & Sylvie Berger & Emmanuel Nony & Béatrice Neau & Benjamin Fould & Anne Licznar & Franck Levasseur & Thomas Guerrier & Sahar Elouej & Sophie Courtade-Gaïani & Nicolas Provost & The Quyen Nguyen & Julien Verdier & David Launay & Frédéric De Ceuninck - 1-20 The H2A.Z and NuRD associated protein HMG20A controls early head and heart developmental transcription programs
by Andreas Herchenröther & Stefanie Gossen & Tobias Friedrich & Alexander Reim & Nadine Daus & Felix Diegmüller & Jörg Leers & Hakimeh Moghaddas Sani & Sarah Gerstner & Leah Schwarz & Inga Stellmacher & Laura Victoria Szymkowiak & Andrea Nist & Thorsten Stiewe & Tilman Borggrefe & Matthias Mann & Joel P. Mackay & Marek Bartkuhn & Annette Borchers & Jie Lan & Sandra B. Hake - 1-20 Interpretable and context-free deconvolution of multi-scale whole transcriptomic data with UniCell deconvolve
by Daniel Charytonowicz & Rachel Brody & Robert Sebra - 1-20 A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene
by Yuandi Gao & Laure Guitton-Sert & Julien Dessapt & Yan Coulombe & Amélie Rodrigue & Larissa Milano & Andréanne Blondeau & Nicolai Balle Larsen & Julien P. Duxin & Samer Hussein & Amélie Fradet-Turcotte & Jean-Yves Masson - 1-20 Spatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer
by Xuejiao Liu & Simin Zhao & Keke Wang & Liting Zhou & Ming Jiang & Yunfeng Gao & Ran Yang & Shiwen Yan & Wen Zhang & Bingbing Lu & Feifei Liu & Ran Zhao & Wenting Liu & Zihan Zhang & Kangdong Liu & Xiang Li & Zigang Dong - 1-20 The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate
by Andreas Lackner & Michael Müller & Magdalena Gamperl & Delyana Stoeva & Olivia Langmann & Henrieta Papuchova & Elisabeth Roitinger & Gerhard Dürnberger & Richard Imre & Karl Mechtler & Paulina A. Latos - 1-20 A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2
by Marta Losa & Iros Barozzi & Marco Osterwalder & Viviana Hermosilla-Aguayo & Angela Morabito & Brandon H. Chacón & Peyman Zarrineh & Ausra Girdziusaite & Jean Denis Benazet & Jianjian Zhu & Susan Mackem & Terence D. Capellini & Diane Dickel & Nicoletta Bobola & Aimée Zuniga & Axel Visel & Rolf Zeller & Licia Selleri - 1-20 Spontaneously evolved progenitor niches escape Yap oncogene addiction in advanced pancreatic ductal adenocarcinomas
by Shigekazu Murakami & Shannon M. White & Alec T. McIntosh & Chan D. K. Nguyen & Chunling Yi - 1-20 Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis
by Richard J. Hewitt & Franz Puttur & David C. A. Gaboriau & Frédéric Fercoq & Maryline Fresquet & William J. Traves & Laura L. Yates & Simone A. Walker & Philip L. Molyneaux & Samuel V. Kemp & Andrew G. Nicholson & Alexandra Rice & Edward Roberts & Rachel Lennon & Leo M. Carlin & Adam J. Byrne & Toby M. Maher & Clare M. Lloyd - 1-20 Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3
by Julia Kornienko & Marta Rodríguez-Martínez & Kai Fenzl & Florian Hinze & Daniel Schraivogel & Markus Grosch & Brigit Tunaj & Dominik Lindenhofer & Laura Schraft & Moritz Kueblbeck & Eric Smith & Chad Mao & Emily Brown & Anjali Owens & Ardan M. Saguner & Benjamin Meder & Victoria Parikh & Michael Gotthardt & Lars M. Steinmetz - 1-20 Retinoic acid signaling modulation guides in vitro specification of human heart field-specific progenitor pools
by Dorota Zawada & Jessica Kornherr & Anna B. Meier & Gianluca Santamaria & Tatjana Dorn & Monika Nowak-Imialek & Daniel Ortmann & Fangfang Zhang & Mark Lachmann & Martina Dreßen & Mariaestela Ortiz & Victoria L. Mascetti & Stephen C. Harmer & Muriel Nobles & Andrew Tinker & Maria Teresa Angelis & Roger A. Pedersen & Phillip Grote & Karl-Ludwig Laugwitz & Alessandra Moretti & Alexander Goedel - 1-20 Apoptotic dysregulation mediates stem cell competition and tissue regeneration
by Marianna Yusupova & Roi Ankawa & Yahav Yosefzon & David Meiri & Ido Bachelet & Yaron Fuchs - 1-20 BRD9-mediated chromatin remodeling suppresses osteoclastogenesis through negative feedback mechanism
by Jiahui Du & Yili Liu & Xiaolin Wu & Jinrui Sun & Junfeng Shi & Hongming Zhang & Ao Zheng & Mingliang Zhou & Xinquan Jiang - 1-20 Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice
by Odette Leiter & David Brici & Stephen J. Fletcher & Xuan Ling Hilary Yong & Jocelyn Widagdo & Nicholas Matigian & Adam B. Schroer & Gregor Bieri & Daniel G. Blackmore & Perry F. Bartlett & Victor Anggono & Saul A. Villeda & Tara L. Walker - 1-20 Inducing multiple nicks promotes interhomolog homologous recombination to correct heterozygous mutations in somatic cells
by Akiko Tomita & Hiroyuki Sasanuma & Tomoo Owa & Yuka Nakazawa & Mayuko Shimada & Takahiro Fukuoka & Tomoo Ogi & Shinichiro Nakada - 1-20 MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia
by Nicholas T. Crump & Alastair L. Smith & Laura Godfrey & Ana M. Dopico-Fernandez & Nicholas Denny & Joe R. Harman & Joseph C. Hamley & Nicole E. Jackson & Catherine Chahrour & Simone Riva & Siobhan Rice & Jaehoon Kim & Venkatesha Basrur & Damian Fermin & Kojo Elenitoba-Johnson & Robert G. Roeder & C. David Allis & Irene Roberts & Anindita Roy & Huimin Geng & James O. J. Davies & Thomas A. Milne - 1-20 A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
by Adriana K. Alexander & Edward J. Rice & Jelena Lujic & Leah E. Simon & Stephanie Tanis & Gilad Barshad & Lina Zhu & Jyoti Lama & Paula E. Cohen & Charles G. Danko - 1-20 Biosynthesized gold nanoparticles that activate Toll-like receptors and elicit localized light-converting hyperthermia for pleiotropic tumor immunoregulation
by Hao Qin & Yang Chen & Zeming Wang & Nan Li & Qing Sun & Yixuan Lin & Wenyi Qiu & Yuting Qin & Long Chen & Hanqing Chen & Yiye Li & Jian Shi & Guangjun Nie & Ruifang Zhao - 1-20 Broad-spectrum kinome profiling identifies CDK6 upregulation as a driver of lenvatinib resistance in hepatocellular carcinoma
by Carmen Oi Ning Leung & Yang Yang & Rainbow Wing Hei Leung & Karl Kam Hei So & Hai Jun Guo & Martina Mang Leng Lei & Gregory Kenneth Muliawan & Yuan Gao & Qian Qian Yu & Jing Ping Yun & Stephanie Ma & Qian Zhao & Terence Kin Wah Lee - 1-20 Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs
by Ganna Petruk & Manoj Puthia & Firdaus Samsudin & Jitka Petrlova & Franziska Olm & Margareta Mittendorfer & Snejana Hyllén & Dag Edström & Ann-Charlotte Strömdahl & Carl Diehl & Simon Ekström & Björn Walse & Sven Kjellström & Peter J. Bond & Sandra Lindstedt & Artur Schmidtchen - 1-20 Antigen recognition detains CD8+ T cells at the blood-brain barrier and contributes to its breakdown
by Sidar Aydin & Javier Pareja & Vivianne M. Schallenberg & Armelle Klopstein & Thomas Gruber & Nicolas Page & Elisa Bouillet & Nicolas Blanchard & Roland Liblau & Jakob Körbelin & Markus Schwaninger & Aaron J. Johnson & Mirjam Schenk & Urban Deutsch & Doron Merkler & Britta Engelhardt - 1-20 ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells
by Jiyeon Lee & Haeryung Lee & Hyein Lee & Miram Shin & Min-Gi Shin & Jinsoo Seo & Eun Jeong Lee & Sun Ah Park & Soochul Park - 1-20 Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development
by Poonam Dhillon & Kelly Ann Mulholland & Hailong Hu & Jihwan Park & Xin Sheng & Amin Abedini & Hongbo Liu & Allison Vassalotti & Junnan Wu & Katalin Susztak - 1-20 Lung endothelial cells regulate pulmonary fibrosis through FOXF1/R-Ras signaling
by Fenghua Bian & Ying-Wei Lan & Shuyang Zhao & Zicheng Deng & Samriddhi Shukla & Anusha Acharya & Johnny Donovan & Tien Le & David Milewski & Matthew Bacchetta & Ahmed Emad Hozain & Yuliya Tipograf & Ya-Wen Chen & Yan Xu & Donglu Shi & Vladimir V. Kalinichenko & Tanya V. Kalin - 1-20 Epigenetic and molecular coordination between HDAC2 and SMAD3-SKI regulates essential brain tumour stem cell characteristics
by Ravinder K. Bahia & Xiaoguang Hao & Rozina Hassam & Orsolya Cseh & Danielle A. Bozek & H. Artee Luchman & Samuel Weiss - 1-20 The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition
by Rakesh Ganji & Joao A. Paulo & Yuecheng Xi & Ian Kline & Jiang Zhu & Christoph S. Clemen & Conrad C. Weihl & John G. Purdy & Steve P. Gygi & Malavika Raman - 1-20 Drosophila motor neuron boutons remodel through membrane blebbing coupled with muscle contraction
by Andreia R. Fernandes & João P. Martins & Edgar R. Gomes & César S. Mendes & Rita O. Teodoro - 1-20 Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer
by Ozge Saatci & Metin Cetin & Meral Uner & Unal Metin Tokat & Ioulia Chatzistamou & Pelin Gulizar Ersan & Elodie Montaudon & Aytekin Akyol & Sercan Aksoy & Aysegul Uner & Elisabetta Marangoni & Mathew Sajish & Ozgur Sahin - 1-20 Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis
by Maria Fankhaenel & Farahnaz S. Golestan Hashemi & Larissa Mourao & Emily Lucas & Manal M. Hosawi & Paul Skipp & Xavier Morin & Colinda L.G.J. Scheele & Salah Elias - 1-20 Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures
by Leland S. Hu & Fulvio D’Angelo & Taylor M. Weiskittel & Francesca P. Caruso & Shannon P. Fortin Ensign & Mylan R. Blomquist & Matthew J. Flick & Lujia Wang & Christopher P. Sereduk & Kevin Meng-Lin & Gustavo Leon & Ashley Nespodzany & Javier C. Urcuyo & Ashlyn C Gonzales & Lee Curtin & Erika M. Lewis & Kyle W. Singleton & Timothy Dondlinger & Aliya Anil & Natenael B. Semmineh & Teresa Noviello & Reyna A. Patel & Panwen Wang & Junwen Wang & Jennifer M. Eschbacher & Andrea Hawkins-Daarud & Pamela R. Jackson & Itamar S. Grunfeld & Christian Elrod & Gina L. Mazza & Sam C. McGee & Lisa Paulson & Kamala Clark-Swanson & Yvette Lassiter-Morris & Kris A. Smith & Peter Nakaji & Bernard R. Bendok & Richard S. Zimmerman & Chandan Krishna & Devi P. Patra & Naresh P. Patel & Mark Lyons & Matthew Neal & Kliment Donev & Maciej M. Mrugala & Alyx B. Porter & Scott C. Beeman & Todd R. Jensen & Kathleen M. Schmainda & Yuxiang Zhou & Leslie C. Baxter & Christopher L. Plaisier & Jing Li & Hu Li & Anna Lasorella & C. Chad Quarles & Kristin R. Swanson & Michele Ceccarelli & Antonio Iavarone & Nhan L. Tran - 1-20 Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination
by Chih-Wei Chou & Chia-Nung Hung & Cheryl Hsiang-Ling Chiu & Xi Tan & Meizhen Chen & Chien-Chin Chen & Moawiz Saeed & Che-Wei Hsu & Michael A. Liss & Chiou-Miin Wang & Zhao Lai & Nathaniel Alvarez & Pawel A. Osmulski & Maria E. Gaczynska & Li-Ling Lin & Veronica Ortega & Nameer B. Kirma & Kexin Xu & Zhijie Liu & Addanki P. Kumar & Josephine A. Taverna & Gopalrao V. N. Velagaleti & Chun-Liang Chen & Zhao Zhang & Tim Hui-Ming Huang - 1-20 NEUROD1 reinforces endocrine cell fate acquisition in pancreatic development
by Romana Bohuslavova & Valeria Fabriciova & Ondrej Smolik & Laura Lebrón-Mora & Pavel Abaffy & Sarka Benesova & Daniel Zucha & Lukas Valihrach & Zuzana Berkova & Frantisek Saudek & Gabriela Pavlinkova - 1-20 mGluR5 is transiently confined in perisynaptic nanodomains to shape synaptic function
by Nicky Scheefhals & Manon Westra & Harold D. MacGillavry - 1-20 Internal states as a source of subject-dependent movement variability are represented by large-scale brain networks
by Macauley Smith Breault & Pierre Sacré & Zachary B. Fitzgerald & John T. Gale & Kathleen E. Cullen & Jorge A. González-Martínez & Sridevi V. Sarma - 1-20 Cdc14 phosphatase counteracts Cdk-dependent Dna2 phosphorylation to inhibit resection during recombinational DNA repair
by Adrián Campos & Facundo Ramos & Lydia Iglesias & Celia Delgado & Eva Merino & Antonio Esperilla-Muñoz & Jaime Correa-Bordes & Andrés Clemente-Blanco - 1-20 Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on an IL23/IFNγ axis
by Jonathan W. Lo & Domenico Cozzetto & James L. Alexander & Nathan P. Danckert & Matthew Madgwick & Naomi Knox & Jillian Yong Xin Sieh & Marton Olbei & Zhigang Liu & Hajir Ibraheim & Jesus Miguens Blanco & Hiromi Kudo & Rocio Castro Seoane & Lucia A. Possamai & Robert Goldin & Julian Marchesi & Tamas Korcsmaros & Graham M. Lord & Nick Powell - 1-20 A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification
by B. Edginton-White & A. Maytum & S. G. Kellaway & D. K. Goode & P. Keane & I. Pagnuco & S. A. Assi & L. Ames & M. Clarke & P. N. Cockerill & B. Göttgens & J. B. Cazier & C. Bonifer - 1-20 Delineating the early dissemination mechanisms of acral melanoma by integrating single-cell and spatial transcriptomic analyses
by Chuanyuan Wei & Wei Sun & Kangjie Shen & Jingqin Zhong & Wanlin Liu & Zixu Gao & Yu Xu & Lu Wang & Tu Hu & Ming Ren & Yinlam Li & Yu Zhu & Shaoluan Zheng & Ming Zhu & Rongkui Luo & Yanwen Yang & Yingyong Hou & Fazhi Qi & Yuhong Zhou & Yong Chen & Jianying Gu - 1-20 RNA splicing analysis using heterogeneous and large RNA-seq datasets
by Jorge Vaquero-Garcia & Joseph K. Aicher & San Jewell & Matthew R. Gazzara & Caleb M. Radens & Anupama Jha & Scott S. Norton & Nicholas F. Lahens & Gregory R. Grant & Yoseph Barash - 1-20 Guided construction of single cell reference for human and mouse lung
by Minzhe Guo & Michael P. Morley & Cheng Jiang & Yixin Wu & Guangyuan Li & Yina Du & Shuyang Zhao & Andrew Wagner & Adnan Cihan Cakar & Michal Kouril & Kang Jin & Nathan Gaddis & Joseph A. Kitzmiller & Kathleen Stewart & Maria C. Basil & Susan M. Lin & Yun Ying & Apoorva Babu & Kathryn A. Wikenheiser-Brokamp & Kyu Shik Mun & Anjaparavanda P. Naren & Geremy Clair & Joshua N. Adkins & Gloria S. Pryhuber & Ravi S. Misra & Bruce J. Aronow & Timothy L. Tickle & Nathan Salomonis & Xin Sun & Edward E. Morrisey & Jeffrey A. Whitsett & Yan Xu - 1-20 Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair
by Durba Pal & Subhadip Ghatak & Kanhaiya Singh & Ahmed Safwat Abouhashem & Manishekhar Kumar & Mohamed S El Masry & Sujit K. Mohanty & Ravichand Palakurti & Yashika Rustagi & Saba Tabasum & Dolly K. Khona & Savita Khanna & Sedat Kacar & Rajneesh Srivastava & Pramod Bhasme & Sumit S. Verma & Edward Hernandez & Anu Sharma & Diamond Reese & Priyanka Verma & Nandini Ghosh & Mahadeo Gorain & Jun Wan & Sheng Liu & Yunlong Liu & Natalia Higuita Castro & Surya C. Gnyawali & William Lawrence & Jordan Moore & Daniel Gallego Perez & Sashwati Roy & Mervin C. Yoder & Chandan K. Sen - 1-20 Continuous multiplexed population representations of task context in the mouse primary visual cortex
by Márton Albert Hajnal & Duy Tran & Michael Einstein & Mauricio Vallejo Martelo & Karen Safaryan & Pierre-Olivier Polack & Peyman Golshani & Gergő Orbán - 1-20 Panoramic analysis of coronaviruses carried by representative bat species in Southern China to better understand the coronavirus sphere
by Yelin Han & Panpan Xu & Yuyang Wang & Wenliang Zhao & Junpeng Zhang & Shuyi Zhang & Jianwei Wang & Qi Jin & Zhiqiang Wu - 1-20 Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma
by Do-Won Jeong & Jong-Wan Park & Kyeong Seog Kim & Jiyoung Kim & June Huh & Jieun Seo & Ye Lee Kim & Joo-Youn Cho & Kwang-Woong Lee & Junji Fukuda & Yang-Sook Chun - 1-20 Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
by Liam McAllan & Damir Baranasic & Sergio Villicaña & Scarlett Brown & Weihua Zhang & Benjamin Lehne & Marco Adamo & Andrew Jenkinson & Mohamed Elkalaawy & Borzoueh Mohammadi & Majid Hashemi & Nadia Fernandes & Nathalie Lambie & Richard Williams & Colette Christiansen & Youwen Yang & Liudmila Zudina & Vasiliki Lagou & Sili Tan & Juan Castillo-Fernandez & James W. D. King & Richie Soong & Paul Elliott & James Scott & Inga Prokopenko & Inês Cebola & Marie Loh & Boris Lenhard & Rachel L. Batterham & Jordana T. Bell & John C. Chambers & Jaspal S. Kooner & William R. Scott - 1-20 Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington’s disease
by Meeli Mullari & Nicolas Fossat & Niels H. Skotte & Andrea Asenjo-Martinez & David T. Humphreys & Jens Bukh & Agnete Kirkeby & Troels K. H. Scheel & Michael L. Nielsen - 1-20 Neuraminidase 1 promotes renal fibrosis development in male mice
by Qian-Qian Chen & Kang Liu & Ning Shi & Gaoxiang Ma & Peipei Wang & Hua-Mei Xie & Si-Jia Jin & Ting-Ting Wei & Xiang-Yu Yu & Yi Wang & Jun-Yuan Zhang & Ping Li & Lian-Wen Qi & Lei Zhang - 1-20 Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments
by Yuzhou Feng & Tianpei Yang & John Zhu & Mabel Li & Maria Doyle & Volkan Ozcoban & Greg T. Bass & Angela Pizzolla & Lachlan Cain & Sirui Weng & Anupama Pasam & Nikolce Kocovski & Yu-Kuan Huang & Simon P. Keam & Terence P. Speed & Paul J. Neeson & Richard B. Pearson & Shahneen Sandhu & David L. Goode & Anna S. Trigos - 1-20 A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer
by Sandra Tietscher & Johanna Wagner & Tobias Anzeneder & Claus Langwieder & Martin Rees & Bettina Sobottka & Natalie Souza & Bernd Bodenmiller - 1-20 The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells
by Aurore Claude-Taupin & Pierre Isnard & Alessia Bagattin & Nicolas Kuperwasser & Federica Roccio & Biagina Ruscica & Nicolas Goudin & Meriem Garfa-Traoré & Alice Regnier & Lisa Turinsky & Martine Burtin & Marc Foretz & Marco Pontoglio & Etienne Morel & Benoit Viollet & Fabiola Terzi & Patrice Codogno & Nicolas Dupont - 1-20 TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells
by Shaun Scaramuzza & Rebecca M. Jones & Martina Muste Sadurni & Alicja Reynolds-Winczura & Divyasree Poovathumkadavil & Abigail Farrell & Toyoaki Natsume & Patricia Rojas & Cyntia Fernandez Cuesta & Masato T. Kanemaki & Marco Saponaro & Agnieszka Gambus - 1-20 Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis
by Nadege Gitego & Bogos Agianian & Oi Wei Mak & Vasantha Kumar MV & Emily H. Cheng & Evripidis Gavathiotis - 1-20 Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair
by Nikolaos Parisis & Pablo D. Dans & Muhammad Jbara & Balveer Singh & Diane Schausi-Tiffoche & Diego Molina-Serrano & Isabelle Brun-Heath & Denisa Hendrychová & Suman Kumar Maity & Diana Buitrago & Rafael Lema & Thiziri Nait Achour & Simona Giunta & Michael Girardot & Nicolas Talarek & Valérie Rofidal & Katerina Danezi & Damien Coudreuse & Marie-Noëlle Prioleau & Robert Feil & Modesto Orozco & Ashraf Brik & Pei-Yun Jenny Wu & Liliana Krasinska & Daniel Fisher - 1-20 Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching
by Jennine M. Dawicki-McKenna & Alex J. Felix & Elisa A. Waxman & Congsheng Cheng & Defne A. Amado & Paul T. Ranum & Alexey Bogush & Lea V. Dungan & Jean Ann Maguire & Alyssa L. Gagne & Elizabeth A. Heller & Deborah L. French & Beverly L. Davidson & Benjamin L. Prosser - 1-20 Regorafenib inhibits EphA2 phosphorylation and leads to liver damage via the ERK/MDM2/p53 axis
by Hao Yan & Wentong Wu & Yuhuai Hu & Jinjin Li & Jiangxin Xu & Xueqin Chen & Zhifei Xu & Xiaochun Yang & Bo Yang & Qiaojun He & Peihua Luo - 1-20 Tau forms synaptic nano-biomolecular condensates controlling the dynamic clustering of recycling synaptic vesicles
by Shanley F. Longfield & Mahdie Mollazade & Tristan P. Wallis & Rachel S. Gormal & Merja Joensuu & Jesse R. Wark & Ashley J. Waardenberg & Christopher Small & Mark E. Graham & Frédéric A. Meunier & Ramón Martínez-Mármol - 1-20 Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
by Filip Mihalič & Leandro Simonetti & Girolamo Giudice & Marie Rubin Sander & Richard Lindqvist & Marie Berit Akpiroro Peters & Caroline Benz & Eszter Kassa & Dilip Badgujar & Raviteja Inturi & Muhammad Ali & Izabella Krystkowiak & Ahmed Sayadi & Eva Andersson & Hanna Aronsson & Ola Söderberg & Doreen Dobritzsch & Evangelia Petsalaki & Anna K. Överby & Per Jemth & Norman E. Davey & Ylva Ivarsson - 1-20 Interleukin-9 production by type 2 innate lymphoid cells induces Paneth cell metaplasia and small intestinal remodeling
by Chengyin Yuan & Aditya Rayasam & Alison Moe & Michael Hayward & Clive Wells & Aniko Szabo & Andrew Mackenzie & Nita Salzman & William R. Drobyski - 1-20 SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma
by Ki-Fong Man & Lei Zhou & Huajian Yu & Ka-Hei Lam & Wei Cheng & Jun Yu & Terence K. Lee & Jing-Ping Yun & Xin-Yuan Guan & Ming Liu & Stephanie Ma - 1-20 Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
by Judith Dönig & Hannah Mende & Jimena Davila Gallesio & Kristina Wagner & Paul Hotz & Kathrin Schunck & Tanja Piller & Soraya Hölper & Sara Uhan & Manuel Kaulich & Matthias Wirth & Ulrich Keller & Georg Tascher & Katherine E. Bohnsack & Stefan Müller - 1-20 An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats
by Mai Iwasaki & Arthur Lefevre & Ferdinand Althammer & Etienne Clauss Creusot & Olga Łąpieś & Hugues Petitjean & Louis Hilfiger & Damien Kerspern & Meggane Melchior & Stephanie Küppers & Quirin Krabichler & Ryan Patwell & Alan Kania & Tim Gruber & Matthew K. Kirchner & Moritz Wimmer & Henning Fröhlich & Laura Dötsch & Jonas Schimmer & Sabine C. Herpertz & Beate Ditzen & Christian P. Schaaf & Kai Schönig & Dusan Bartsch & Anna Gugula & Aleksandra Trenk & Anna Blasiak & Javier E. Stern & Pascal Darbon & Valery Grinevich & Alexandre Charlet - 1-20 DAXX drives de novo lipogenesis and contributes to tumorigenesis
by Iqbal Mahmud & Guimei Tian & Jia Wang & Tarun E. Hutchinson & Brandon J. Kim & Nikee Awasthee & Seth Hale & Chengcheng Meng & Allison Moore & Liming Zhao & Jessica E. Lewis & Aaron Waddell & Shangtao Wu & Julia M. Steger & McKenzie L. Lydon & Aaron Chait & Lisa Y. Zhao & Haocheng Ding & Jian-Liang Li & Hamsa Thayele Purayil & Zhiguang Huo & Yehia Daaka & Timothy J. Garrett & Daiqing Liao - 1-20 PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions
by Xiaocen Jin & Hikari Tanaka & Meihua Jin & Kyota Fujita & Hidenori Homma & Maiko Inotsume & Huang Yong & Kenichi Umeda & Noriyuki Kodera & Toshio Ando & Hitoshi Okazawa - 1-20 Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma
by Bruna Calsina & Elena Piñeiro-Yáñez & Ángel M. Martínez-Montes & Eduardo Caleiras & Ángel Fernández-Sanromán & María Monteagudo & Rafael Torres-Pérez & Coral Fustero-Torre & Marta Pulgarín-Alfaro & Eduardo Gil & Rocío Letón & Scherezade Jiménez & Santiago García-Martín & Maria Carmen Martin & Juan María Roldán-Romero & Javier Lanillos & Sara Mellid & María Santos & Alberto Díaz-Talavera & Ángeles Rubio & Patricia González & Barbara Hernando & Nicole Bechmann & Margo Dona & María Calatayud & Sonsoles Guadalix & Cristina Álvarez-Escolá & Rita M. Regojo & Javier Aller & Maria Isabel Del Olmo-Garcia & Adrià López-Fernández & Stephanie M. J. Fliedner & Elena Rapizzi & Martin Fassnacht & Felix Beuschlein & Marcus Quinkler & Rodrigo A. Toledo & Massimo Mannelli & Henri J. Timmers & Graeme Eisenhofer & Sandra Rodríguez-Perales & Orlando Domínguez & Geoffrey Macintyre & Maria Currás-Freixes & Cristina Rodríguez-Antona & Alberto Cascón & Luis J. Leandro-García & Cristina Montero-Conde & Giovanna Roncador & Juan Fernando García-García & Karel Pacak & Fátima Al-Shahrour & Mercedes Robledo - 1-20 The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling
by Kellianne D. Alexander & Shankar Ramachandran & Kasturi Biswas & Christopher M. Lambert & Julia Russell & Devyn B. Oliver & William Armstrong & Monika Rettler & Samuel Liu & Maria Doitsidou & Claire Bénard & Amy K. Walker & Michael M. Francis - 1-20 Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses
by Taghreed Hirz & Shenglin Mei & Hirak Sarkar & Youmna Kfoury & Shulin Wu & Bronte M. Verhoeven & Alexander O. Subtelny & Dimitar V. Zlatev & Matthew W. Wszolek & Keyan Salari & Evan Murray & Fei Chen & Evan Z. Macosko & Chin-Lee Wu & David T. Scadden & Douglas M. Dahl & Ninib Baryawno & Philip J. Saylor & Peter V. Kharchenko & David B. Sykes - 1-20 MYTHO is a novel regulator of skeletal muscle autophagy and integrity
by Jean-Philippe Leduc-Gaudet & Anais Franco-Romero & Marina Cefis & Alaa Moamer & Felipe E. Broering & Giulia Milan & Roberta Sartori & Tomer Jordi Chaffer & Maude Dulac & Vincent Marcangeli & Dominique Mayaki & Laurent Huck & Anwar Shams & José A. Morais & Elise Duchesne & Hanns Lochmuller & Marco Sandri & Sabah N. A. Hussain & Gilles Gouspillou - 1-20 Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment
by Thillai V. Sekar & Eslam A. Elghonaimy & Katy L. Swancutt & Sebastian Diegeler & Isaac Gonzalez & Cassandra Hamilton & Peter Q. Leung & Jens Meiler & Cristina E. Martina & Michael Whitney & Todd A. Aguilera - 1-20 Molecular landscape and functional characterization of centrosome amplification in ovarian cancer
by Carolin M. Sauer & James A. Hall & Dominique-Laurent Couturier & Thomas Bradley & Anna M. Piskorz & Jacob Griffiths & Ashley Sawle & Matthew D. Eldridge & Philip Smith & Karen Hosking & Marika A. V. Reinius & Lena Morrill Gavarró & Anne-Marie Mes-Masson & Darren Ennis & David Millan & Aoisha Hoyle & Iain A. McNeish & Mercedes Jimenez-Linan & Filipe Correia Martins & Julia Tischer & Maria Vias & James D. Brenton - 1-20 Broad phosphorylation mediated by testis-specific serine/threonine kinases contributes to spermiogenesis and male fertility
by Xuedi Zhang & Ju Peng & Menghua Wu & Angyang Sun & Xiangyu Wu & Jie Zheng & Wangfei Shi & Guanjun Gao - 1-20 Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution
by Ryann M. Fame & Peter N. Kalugin & Boryana Petrova & Huixin Xu & Paul A. Soden & Frederick B. Shipley & Neil Dani & Bradford Grant & Aja Pragana & Joshua P. Head & Suhasini Gupta & Morgan L. Shannon & Fortunate F. Chifamba & Hannah Hawks-Mayer & Amanda Vernon & Fan Gao & Yong Zhang & Michael J. Holtzman & Myriam Heiman & Mark L. Andermann & Naama Kanarek & Jonathan O. Lipton & Maria K. Lehtinen - 1-20 Dynamical latent state computation in the male macaque posterior parietal cortex
by Kaushik J. Lakshminarasimhan & Eric Avila & Xaq Pitkow & Dora E. Angelaki - 1-20 A defect in mitochondrial protein translation influences mitonuclear communication in the heart
by Feng Gao & Tian Liang & Yao Wei Lu & Xuyang Fu & Xiaoxuan Dong & Linbin Pu & Tingting Hong & Yuxia Zhou & Yu Zhang & Ning Liu & Feng Zhang & Jianming Liu & Andrea P. Malizia & Hong Yu & Wei Zhu & Douglas B. Cowan & Hong Chen & Xinyang Hu & John D. Mably & Jian’an Wang & Da-Zhi Wang & Jinghai Chen - 1-20 Cellular state landscape and herpes simplex virus type 1 infection progression are connected
by Maija K. Pietilä & Jana J. Bachmann & Janne Ravantti & Lucas Pelkmans & Cornel Fraefel - 1-20 Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury
by Yongheng Fan & Xianming Wu & Sufang Han & Qi Zhang & Zheng Sun & Bing Chen & Xiaoyu Xue & Haipeng Zhang & Zhenni Chen & Man Yin & Zhifeng Xiao & Yannan Zhao & Jianwu Dai - 1-20 TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation
by Miho M. Suzuki & Kenta Iijima & Koichi Ogami & Keiko Shinjo & Yoshiteru Murofushi & Jingqi Xie & Xuebing Wang & Yotaro Kitano & Akira Mamiya & Yuji Kibe & Tatsunori Nishimura & Fumiharu Ohka & Ryuta Saito & Shinya Sato & Junya Kobayashi & Ryoji Yao & Kanjiro Miyata & Kazunori Kataoka & Hiroshi I. Suzuki & Yutaka Kondo - 1-20 M1BP is an essential transcriptional activator of oxidative metabolism during Drosophila development
by Gabriela Poliacikova & Marine Barthez & Thomas Rival & Aïcha Aouane & Nuno Miguel Luis & Fabrice Richard & Fabrice Daian & Nicolas Brouilly & Frank Schnorrer & Corinne Maurel-Zaffran & Yacine Graba & Andrew J. Saurin - 1-20 The usherin mutation c.2299delG leads to its mislocalization and disrupts interactions with whirlin and VLGR1
by Lars Tebbe & Maggie L. Mwoyosvi & Ryan Crane & Mustafa S. Makia & Mashal Kakakhel & Dominic Cosgrove & Muayyad R. Al-Ubaidi & Muna I. Naash - 1-20 Hippocampal firing fields anchored to a moving object predict homing direction during path-integration-based behavior
by Maryam Najafian Jazi & Adrian Tymorek & Ting-Yun Yen & Felix Jose Kavarayil & Moritz Stingl & Sherman Richard Chau & Benay Baskurt & Celia García Vilela & Kevin Allen - 1-20 Single-cell spatial metabolomics with cell-type specific protein profiling for tissue systems biology
by Thomas Hu & Mayar Allam & Shuangyi Cai & Walter Henderson & Brian Yueh & Aybuke Garipcan & Anton V. Ievlev & Maryam Afkarian & Semir Beyaz & Ahmet F. Coskun - 1-20 Oxidized mitochondrial DNA induces gasdermin D oligomerization in systemic lupus erythematosus
by Naijun Miao & Zhuning Wang & Qinlan Wang & Hongyan Xie & Ninghao Yang & Yanzhe Wang & Jin Wang & Haixia Kang & Wenjuan Bai & Yuanyuan Wang & Rui He & Kepeng Yan & Yang Wang & Qiongyi Hu & Zhaoyuan Liu & Fubin Li & Feng Wang & Florent Ginhoux & Xiaoling Zhang & Jianyong Yin & Limin Lu & Jing Wang - 1-20 Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex
by Komal Soni & Anusree Sivadas & Attila Horvath & Nikolay Dobrev & Rippei Hayashi & Leo Kiss & Bernd Simon & Klemens Wild & Irmgard Sinning & Tamás Fischer - 1-20 SRC and TKS5 mediated podosome formation in fibroblasts promotes extracellular matrix invasion and pulmonary fibrosis
by Ilianna Barbayianni & Paraskevi Kanellopoulou & Dionysios Fanidis & Dimitris Nastos & Eleftheria-Dimitra Ntouskou & Apostolos Galaris & Vaggelis Harokopos & Pantelis Hatzis & Eliza Tsitoura & Robert Homer & Naftali Kaminski & Katerina M. Antoniou & Bruno Crestani & Argyrios Tzouvelekis & Vassilis Aidinis - 1-20 Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss
by Laura Rüland & Francesco Andreatta & Simone Massalini & Susana Chuva de Sousa Lopes & Hans Clevers & Delilah Hendriks & Benedetta Artegiani - 1-20 Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex
by Timothy R. Young & Mariko Yamamoto & Satomi S. Kikuchi & Aya C. Yoshida & Takaya Abe & Kenichi Inoue & Joshua P. Johansen & Andrea Benucci & Yumiko Yoshimura & Tomomi Shimogori - 1-20 Tryptase β regulation of joint lubrication and inflammation via proteoglycan-4 in osteoarthritis
by Nabangshu Das & Luiz G. N. Almeida & Afshin Derakhshani & Daniel Young & Kobra Mehdinejadiani & Paul Salo & Alexander Rezansoff & Gregory D. Jay & Christian P. Sommerhoff & Tannin A. Schmidt & Roman Krawetz & Antoine Dufour - 1-20 Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles
by Flavia A. Graca & Anna Stephan & Benjamin A. Minden-Birkenmaier & Abbas Shirinifard & Yong-Dong Wang & Fabio Demontis & Myriam Labelle - 1-20 A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets
by Péter István Kulcsár & András Tálas & Zoltán Ligeti & Eszter Tóth & Zsófia Rakvács & Zsuzsa Bartos & Sarah Laura Krausz & Ágnes Welker & Vanessza Laura Végi & Krisztina Huszár & Ervin Welker - 1-20 ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling
by Maximilian Hirschenberger & Alice Lepelley & Ulrich Rupp & Susanne Klute & Victoria Hunszinger & Lennart Koepke & Veronika Merold & Blaise Didry-Barca & Fanny Wondany & Tim Bergner & Tatiana Moreau & Mathieu P. Rodero & Reinhild Rösler & Sebastian Wiese & Stefano Volpi & Marco Gattorno & Riccardo Papa & Sally-Ann Lynch & Marte G. Haug & Gunnar Houge & Kristen M. Wigby & Jessica Sprague & Jerica Lenberg & Clarissa Read & Paul Walther & Jens Michaelis & Frank Kirchhoff & Carina C. Oliveira Mann & Yanick J. Crow & Konstantin M. J. Sparrer - 1-20 Hierarchical fluctuation shapes a dynamic flow linked to states of consciousness
by Ang Li & Haiyang Liu & Xu Lei & Yini He & Qian Wu & Yan Yan & Xin Zhou & Xiaohan Tian & Yingjie Peng & Shangzheng Huang & Kaixin Li & Meng Wang & Yuqing Sun & Hao Yan & Cheng Zhang & Sheng He & Ruquan Han & Xiaoqun Wang & Bing Liu - 1-20 Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity
by Benedikt Goretzki & Christoph Wiedemann & Brett A. McCray & Stefan L. Schäfer & Jasmin Jansen & Frederike Tebbe & Sarah-Ana Mitrovic & Julia Nöth & Ainara Claveras Cabezudo & Jack K. Donohue & Cy M. Jeffries & Wieland Steinchen & Florian Stengel & Charlotte J. Sumner & Gerhard Hummer & Ute A. Hellmich - 1-20 REPTOR and CREBRF encode key regulators of muscle energy metabolism
by Pedro Saavedra & Phillip A. Dumesic & Yanhui Hu & Elizabeth Filine & Patrick Jouandin & Richard Binari & Sarah E. Wilensky & Jonathan Rodiger & Haiyun Wang & Weihang Chen & Ying Liu & Bruce M. Spiegelman & Norbert Perrimon - 1-20 ANKS1B encoded AIDA-1 regulates social behaviors by controlling oligodendrocyte function
by Chang Hoon Cho & Ilana Vasilisa Deyneko & Dylann Cordova-Martinez & Juan Vazquez & Anne S. Maguire & Jenny R. Diaz & Abigail U. Carbonell & Jaafar O. Tindi & Min-Hui Cui & Roman Fleysher & Sophie Molholm & Michael L. Lipton & Craig A. Branch & Louis Hodgson & Bryen A. Jordan - 1-20 Tissue-resident B cells orchestrate macrophage polarisation and function
by Ondrej Suchanek & John R. Ferdinand & Zewen K. Tuong & Sathi Wijeyesinghe & Anita Chandra & Ann-Katrin Clauder & Larissa N. Almeida & Simon Clare & Katherine Harcourt & Christopher J. Ward & Rachael Bashford-Rogers & Trevor Lawley & Rudolf A. Manz & Klaus Okkenhaug & David Masopust & Menna R. Clatworthy - 1-20 Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia
by Matteo Maria Naldini & Gabriele Casirati & Matteo Barcella & Paola Maria Vittoria Rancoita & Andrea Cosentino & Carolina Caserta & Francesca Pavesi & Erika Zonari & Giacomo Desantis & Diego Gilioli & Matteo Giovanni Carrabba & Luca Vago & Massimo Bernardi & Raffaella Micco & Clelia Serio & Ivan Merelli & Monica Volpin & Eugenio Montini & Fabio Ciceri & Bernhard Gentner - 1-20 Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis
by Yuichi Tsuchiya & Takao Seki & Kenta Kobayashi & Sachiko Komazawa-Sakon & Shigeyuki Shichino & Takashi Nishina & Kyoko Fukuhara & Kenichi Ikejima & Hidenari Nagai & Yoshinori Igarashi & Satoshi Ueha & Akira Oikawa & Shinya Tsurusaki & Soh Yamazaki & Chiharu Nishiyama & Tetuo Mikami & Hideo Yagita & Ko Okumura & Taketomo Kido & Atsushi Miyajima & Kouji Matsushima & Mai Imasaka & Kimi Araki & Toru Imamura & Masaki Ohmuraya & Minoru Tanaka & Hiroyasu Nakano - 1-20 Cytolytic circumsporozoite-specific memory CD4+ T cell clones are expanded during Plasmodium falciparum infection
by Raquel Furtado & Mahinder Paul & Jinghang Zhang & Joowhan Sung & Paul Karell & Ryung S. Kim & Sophie Caillat-Zucman & Li Liang & Philip Felgner & Andy Bauleni & Syze Gama & Andrea Buchwald & Terrie Taylor & Karl Seydel & Miriam Laufer & Fabien Delahaye & Johanna P. Daily & Grégoire Lauvau - 1-20 Illuminating the mechanism and allosteric behavior of NanoLuc luciferase
by Michal Nemergut & Daniel Pluskal & Jana Horackova & Tereza Sustrova & Jan Tulis & Tomas Barta & Racha Baatallah & Glwadys Gagnot & Veronika Novakova & Marika Majerova & Karolina Sedlackova & Sérgio M. Marques & Martin Toul & Jiri Damborsky & Zbynek Prokop & David Bednar & Yves L. Janin & Martin Marek - 1-20 A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia
by Anna Laddach & Song Hui Chng & Reena Lasrado & Fränze Progatzky & Michael Shapiro & Alek Erickson & Marisol Sampedro Castaneda & Artem V. Artemov & Ana Carina Bon-Frauches & Eleni-Maria Amaniti & Jens Kleinjung & Stefan Boeing & Sila Ultanir & Igor Adameyko & Vassilis Pachnis - 1-20 Antigen footprint governs activation of the B cell receptor
by Alexey Ferapontov & Marjan Omer & Isabelle Baudrexel & Jesper Sejrup Nielsen & Daniel Miotto Dupont & Kristian Juul-Madsen & Philipp Steen & Alexandra S. Eklund & Steffen Thiel & Thomas Vorup-Jensen & Ralf Jungmann & Jørgen Kjems & Søren Egedal Degn - 1-20 Salicylic acid metabolism and signalling coordinate senescence initiation in aspen in nature
by Jenna Lihavainen & Jan Šimura & Pushan Bag & Nazeer Fataftah & Kathryn Megan Robinson & Nicolas Delhomme & Ondřej Novák & Karin Ljung & Stefan Jansson - 1-20 Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration
by Andrea Toth & Paranthaman Kannan & John Snowball & Matthew Kofron & Joseph A. Wayman & James P. Bridges & Emily R. Miraldi & Daniel Swarr & William J. Zacharias - 1-20 Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk
by Pingting Ying & Can Chen & Zequn Lu & Shuoni Chen & Ming Zhang & Yimin Cai & Fuwei Zhang & Jinyu Huang & Linyun Fan & Caibo Ning & Yanmin Li & Wenzhuo Wang & Hui Geng & Yizhuo Liu & Wen Tian & Zhiyong Yang & Jiuyang Liu & Chaoqun Huang & Xiaojun Yang & Bin Xu & Heng Li & Xu Zhu & Ni Li & Bin Li & Yongchang Wei & Ying Zhu & Jianbo Tian & Xiaoping Miao - 1-20 Lateral hypothalamic proenkephalin neurons drive threat-induced overeating associated with a negative emotional state
by In-Jee You & Yeeun Bae & Alec R. Beck & Sora Shin - 1-20 EB1 decoration of microtubule lattice facilitates spindle-kinetochore lateral attachment in Plasmodium male gametogenesis
by Shuzhen Yang & Mengya Cai & Junjie Huang & Shengnan Zhang & Xiaoli Mo & Kai Jiang & Huiting Cui & Jing Yuan - 1-20 Molecular basis and cellular functions of vinculin-actin directional catch bonding
by Venkat R. Chirasani & Mohammad Ashhar I. Khan & Juilee N. Malavade & Nikolay V. Dokholyan & Brenton D. Hoffman & Sharon L. Campbell - 1-20 Activation of ILC2s through constitutive IFNγ signaling reduction leads to spontaneous pulmonary fibrosis
by Natsuko Otaki & Yasutaka Motomura & Tommy Terooatea & S. Thomas Kelly & Miho Mochizuki & Natsuki Takeno & Shigeo Koyasu & Miu Tamamitsu & Fuminori Sugihara & Junichi Kikuta & Hideya Kitamura & Yoshiki Shiraishi & Jun Miyanohara & Yuji Nagano & Yuji Saita & Takashi Ogura & Koichiro Asano & Aki Minoda & Kazuyo Moro - 1-20 SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activity
by Feng Wang & Yang Gao & Situ Xue & Luyao Zhao & Huimin Jiang & Tingting Zhang & Yunxuan Li & Chenxi Zhao & Fan Wu & Tana Siqin & Ying Liu & Jie Wu & Yechao Yan & Jian Yuan & Jian-dong Jiang & Ke Li - 1-20 Bacteroides Fragilis in the gut microbiomes of Alzheimer’s disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice
by Yiyuan Xia & Yifan Xiao & Zhi-Hao Wang & Xia Liu & Ashfaqul M. Alam & John P. Haran & Beth A. McCormick & Xiji Shu & Xiaochuan Wang & Keqiang Ye - 1-20 CTCF controls three-dimensional enhancer network underlying the inflammatory response of bone marrow-derived dendritic cells
by Bobae Yang & Sueun Kim & Woong-Jae Jung & Kyungwoo Kim & Sugyung Kim & Yong-Jin Kim & Tae-Gyun Kim & Eun-Chong Lee & Jung-Sik Joo & Chae Gyu Park & Sumin Oh & Kyung Hyun Yoo & Hyoung-Pyo Kim - 1-20 Single-cell analysis of lizard blastema fibroblasts reveals phagocyte-dependent activation of Hedgehog-responsive chondrogenesis
by Ariel C. Vonk & Xiaofan Zhao & Zheyu Pan & Megan L. Hudnall & Conrad G. Oakes & Gabriela A. Lopez & Sarah C. Hasel-Kolossa & Alexander W. C. Kuncz & Sasha B. Sengelmann & Darian J. Gamble & Thomas P. Lozito - 1-20 Custom tuning of Rieske oxygenase reactivity
by Jiayi Tian & Jianxin Liu & Madison Knapp & Patrick H. Donnan & David G. Boggs & Jennifer Bridwell-Rabb - 1-20 MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ
by Sandra Schrenk & Lindsay J. Bischoff & Jillian Goines & Yuqi Cai & Shruti Vemaraju & Yoshinobu Odaka & Samantha R. Good & Joseph S. Palumbo & Sara Szabo & Damien Reynaud & Catherine D. Raamsdonk & Richard A. Lang & Elisa Boscolo - 1-20 The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation
by Johannes Benedum & Vedran Franke & Lisa-Marie Appel & Lena Walch & Melania Bruno & Rebecca Schneeweiss & Juliane Gruber & Helena Oberndorfer & Emma Frank & Xué Strobl & Anton Polyansky & Bojan Zagrovic & Altuna Akalin & Dea Slade - 1-20 A transcriptional network required for bradyzoite development in Toxoplasma gondii is dispensable for recrudescent disease
by Sarah L. Sokol-Borrelli & Sarah M. Reilly & Michael J. Holmes & Stephanie B. Orchanian & Mackenzie D. Massmann & Katherine G. Sharp & Leah F. Cabo & Hisham S. Alrubaye & Bruno Martorelli Di Genova & Melissa B. Lodoen & William J. Sullivan & Jon P. Boyle - 1-20 Homology directed telomere clustering, ultrabright telomere formation and nuclear envelope rupture in cells lacking TRF2B and RAP1
by Rekha Rai & Kevin Biju & Wenqi Sun & Tori Sodeinde & Amer Al-Hiyasat & Jaida Morgan & Xianwen Ye & Xueqing Li & Yong Chen & Sandy Chang - 1-20 Structural titration reveals Ca2+-dependent conformational landscape of the IP3 receptor
by Navid Paknejad & Vinay Sapuru & Richard K. Hite