Content
November 1999, Volume 402, Issue 6760
- 5-11 The alliance of genes and environment in asthma and allergy
by William Cookson - 12-17 The role of allergy in the development of asthma
by P. G. Holt & C. Macaubas & P. A. Stumbles & P. D. Sly - 18-23 Induction and regulation of the IgE response
by David B. Corry & Farrah Kheradmand - 24-30 Signalling through the high-affinity IgE receptor FcεRI
by Helen Turner & Jean-Pierre Kinet - 31-38 Therapeutic strategies for allergic diseases
by Peter J. Barnes - 40-40 Schering-Plough and allergic disease
by Francis Cuss - 331-331 ‘It's a G’: the one-billionth nucleotide
by David Dickson & Colin Macilwain - 331-332 German bioethics inquiry ‘could hold up essential changes’
by Quirin Schiermeier - 332-332 Concern at cheap AIDS drug fears
by Michael Cherry - 332-332 Israel urged to set up labs to carry out military research
by Haim Watzman - 333-333 Praise greets accuracy of Leonid prediction
by Tony Reichhardt - 333-334 Brookhaven leak reactor to close
by Colin Macilwain - 334-334 Science lobby ‘ecstatic’ after triumph in NIH budget battle
by Meredith Wadman - 334-335 Hughes institute unveils top team
by Colin Macilwain - 335-335 Busquin plans white paper to integrate European research
by Keith Nuttall - 335-335 Genentech pays $200m over growth hormone ‘theft’
by Rex Dalton & Quirin Schiermeier - 336-336 China on verge of putting man into space…
by Tian Xuewen - 336-336 …as a new failed satellite launch embarrasses Japan
by Asako Saegusa - 337-337 Gender discrimination ‘undermines science’
by Natasha Loder - 342-343 India intends to reap the full commercial benefits
by K. S. Jayaraman - 343-344 Access issues may determine whether agri-biotech will help the world's poor
by Colin Macilwain - 344-345 Smugglers aim to circumvent GM court ban in Brazil
by Ricardo Bonalume Neto - 345-345 Academies link to map scientific priorities for meeting real needs
by David Dickson - 347-347 Promoting a standard nomenclature for genes and proteins
by Julia White & Hester Wain & Elspeth Bruford & Sue Povey - 347-347 Sequencing challenge
by Lois J. Maltais & Ian Jackson - 347-348 What's in a name?
by Tony Smith - 348-348 Cooperative efforts around Lake Tahoe
by Stephen G. Wells & James S. Coleman & Joseph N. Crowley & Kenneth W. Hunter - 348-348 Precautionary approach to risk assessment
by Alister Scott & Andy Stirling & Nick Mabey & Frans Berkhout & Chris Williams & Chris Rose & Michael Jacobs & Robin Grove-White & Ian Scoones & Melissa Leach - 349-350 Mastering the art of the skies
by Euan Nisbet - 350-350 Personal views of an impersonal world
by Howard P. Segal - 351-351 A friend of one's own
by Paul L. Harris - 351-352 Sniffing the world of olfaction
by Vincent Dusastre - 353-353 Two millennia of animal spirits
by Ian Glynn - 355-355 Emortality — at last!
by Brian Stableford - 357-358 Plug-in quantum software
by John Preskill - 358-359 The family tree flowers
by Paul Kenrick - 359-361 Clouds from near and far
by W. Butler Burton & Robert Braun - 362-363 What do yeast proteins do?
by Philip Hieter - 363-365 Sulphur in the mix
by Ronald P. Kiene - 365-366 Ancestral primate viewed
by Stephen J. O'Brien & Roscoe Stanyon - 366-367 Competition and coexistence
by Ulrich Sommer - 367-367 Internal ecology
by David Jones - 368-368 Charles M. Steinberg (1932–99)
by Jack von Borstel & John Cairns - 369-370 Feeding by mandibular raking in a snake
by N. J. Kley & E. L. Brainerd - 370-371 A universal marker for transgenic insects
by Andreas J. Berghammer & Martin Klingler & Ernst A. Wimmer - 371-372 Ubiquitin tag for sperm mitochondria
by Peter Sutovsky & Ricardo D. Moreno & João Ramalho-Santos & Tanja Dominko & Calvin Simerly & Gerald Schatten - 372-372 Iron, nitrogen and phosphorus in the ocean
by John J. Cullen - 372-372 reply: Iron, nitrogen and phosphorus in the ocean
by Toby Tyrrell - 373-376 Active site-directed protein regulation
by Bostjan Kobe & Bruce E. Kemp - 377-385 Structure of fumarate reductase from Wolinella succinogenes at 2.2 Å resolution
by C. Roy D. Lancaster & Achim Kröger & Manfred Auer & Hartmut Michel - 386-387 Discovery of molecular hydrogen in a high-velocity cloud of the Galactic halo
by P. Richter & K. S. de Boer & H. Widmann & N. Kappelmann & W. Gringel & M. Grewing & J. Barnstedt - 388-390 Accretion of low-metallicity gas by the Milky Way
by B. P. Wakker & J. C. Howk & B. D. Savage & H. van Woerden & S. L. Tufte & U. J. Schwarz & R. Benjamin & R. J. Reynolds & R. F. Peletier & P. M. W. Kalberla - 390-393 Demonstrating the viability of universal quantum computation using teleportation and single-qubit operations
by Daniel Gottesman & Isaac L. Chuang - 393-395 Coupled synthesis and self-assembly of nanoparticles to give structures with controlled organization
by Mei Li & Heimo Schnablegger & Stephen Mann - 396-399 Role of vertical mixing in controlling the oceanic production of dimethyl sulphide
by Rafel Simó & Carlos Pedrós-Alió - 399-401 The effect of climate change on ozone depletion through changes in stratospheric water vapour
by Daniel B. Kirk-Davidoff & Eric J. Hintsa & James G. Anderson & David W. Keith - 402-404 Angiosperm phylogeny inferred from multiple genes as a tool for comparative biology
by Pamela S. Soltis & Douglas E. Soltis & Mark W. Chase - 404-407 The earliest angiosperms: evidence from mitochondrial, plastid and nuclear genomes
by Yin-Long Qiu & Jungho Lee & Fabiana Bernasconi-Quadroni & Douglas E. Soltis & Pamela S. Soltis & Michael Zanis & Elizabeth A. Zimmer & Zhiduan Chen & Vincent Savolainen & Mark W. Chase - 407-410 Biodiversity of plankton by species oscillations and chaos
by Jef Huisman & Franz J. Weissing - 411-413 The dynamics of chromosome evolution in birds and mammals
by David W. Burt & Charlotte Bruley & Ian C. Dunn & Cheryl T. Jones & Anne Ramage & Andy S. Law & David R. Morrice & Ian R. Paton & Jacqueline Smith & Dawn Windsor & Alexei Sazanov & Ruedi Fries & David Waddington - 413-418 Large-scale analysis of the yeast genome by transposon tagging and gene disruption
by Petra Ross-Macdonald & Paulo S. R. Coelho & Terry Roemer & Seema Agarwal & Anuj Kumar & Ronald Jansen & Kei-Hoi Cheung & Amy Sheehan & Dawn Symoniatis & Lara Umansky & Matthew Heidtman & F. Kenneth Nelson & Hiroshi Iwasaki & Karl Hager & Mark Gerstein & Perry Miller & G. Shirleen Roeder & Michael Snyder - 418-421 Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast
by John J. Wyrick & Frank C. P. Holstege & Ezra G. Jennings & Helen C. Causton & David Shore & Michael Grunstein & Eric S. Lander & Richard A. Young - 421-425 LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite
by N. Toni & P.-A. Buchs & I. Nikonenko & C. R. Bron & D. Muller - 425-429 Conserved regulation of proximodistal limb axis development by Meis1/Hth
by Nadia Mercader & Esther Leonardo & Natalia Azpiazu & Antonio Serrano & Ginés Morata & Carlos Martínez-A & Miguel Torres - 429-433 CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid
by Roberto Weigert & Maria Giuseppina Silletta & Stefania Spanò & Gabriele Turacchio & Claudia Cericola & Antonino Colanzi & Silvia Senatore & Raffaella Mancini & Elena V. Polishchuk & Mario Salmona & Francesco Facchiano & Koert N. J. Burger & Alexander Mironov & Alberto Luini & Daniela Corda - 434-439 Crystal structures of the membrane-binding C2 domain of human coagulation factor V
by Sandra Macedo-Ribeiro & Wolfram Bode & Robert Huber & Mary Ann Quinn-Allen & Suhng Wook Kim & Thomas L. Ortel & Gleb P. Bourenkov & Hans D. Bartunik & Milton T. Stubbs & William H. Kane & Pablo Fuentes-Prior - 439-442 Structure of the C2 domain of human factor VIII at 1.5 Å resolution
by Kathleen P. Pratt & Betty W. Shen & Kazuya Takeshima & Earl W. Davie & Kazuo Fujikawa & Barry L. Stoddard - 442-442 addendum: Energetic constraints on the diet of terrestrial carnivores
by Chris Carbone & Georgina M. Mace & S. Craig Roberts & David W. Macdonald
November 1999, Volume 402, Issue 6759
- 219-219 Scientists reel after Indian cyclone
by K.S. Jayaraman - 219-220 Alliance of US labs plans to build map of cell signalling pathways
by Alison Abbott - 220-220 Japan calls for partnership to develop semiconductors
by Asako Saegusa - 221-221 France could face ‘scientific recession’, warns council
by Heather McCabe - 221-222 Concern over Mars Lander as inquiry reports on Orbiter loss
by Tony Reichhardt - 222-222 Professors use web to catch students who plagiarize…
by Rex Dalton - 222-222 … and author gets similar paper retracted
by Rex Dalton - 223-223 Privatization of UK weapons labs under fire
by Natasha Loder - 223-224 Jobs boost for Spanish science
by Xavier Bosch - 224-224 Body takes centre stage in UK's Millennium Dome
by Natasha Loder - 224-224 Opposition pledges to raise New Zealand science budget
by Peter Pockley - 225-225 AZT critics ‘swayed South African president’
by Mike Cherry - 225-225 Russian peace researcher detained
by Carl Levitin - 229-229 Genetically modified foods face rigorous safety evaluation
by M. J. Gasson - 229-230 Bureaucracy blights Japan's safety record
by Kazuo Inoue - 230-230 Unfair exchange
by David Colquhoun - 230-230 Challenge for global e-journal project
by Lance Sultzbaugh - 230-230 How the Church moves with the times
by Guy Consolmagno - 231-232 Much food, many problems
by Anthony Trewavas - 233-234 Creating a climate for change
by Nancy Kete - 234-235 Let them think cake
by Marian Stamp Dawkins - 235-236 Cajal's scientific prescience revisited
by Harvey J. Karten - 236-236 Science in culture
by Martin Kemp - 237-237 Achilles and the maggots
by Paolo Mazzarello - 239-239 When thought-mail fails
by Ian Watson - 241-242 Fishing for function in noise
by James J. Collins - 242-243 Open season for solid frameworks
by Michael J. Zaworotko - 243-245 Mutant mice live longer
by Leonard Guarente - 245-247 Molten rocks in motion
by Michael R. Perfit - 247-249 What makes ATP synthase spin?
by Paul D. Boyer - 249-249 Frankenstein lives!
by David Jones - 250-250 Guido Pontecorvo (1907–99)
by Obaid Siddiqi - 251-251 Why ‘false’ colours are seen by butterflies
by Almut Kelber - 251-253 Ferromagnetism in the hexaborides
by M. E. Zhitomirsky & T. M. Rice & V. I. Anisimov - 253-253 Variable cell number in nematodes
by Ana Cunha & Ricardo B. R. Azevedo & Scott W. Emmons & Armand M. Leroi - 253-254 Growing Y-junction carbon nanotubes
by Jing Li & Chris Papadopoulos & Jimmy Xu - 255-262 Selecting and maintaining a diverse T-cell repertoire
by Ananda W. Goldrath & Michael J. Bevan - 263-268 Structural changes linked to proton translocation by subunit c of the ATP synthase
by Vinit K. Rastogi & Mark E. Girvin - 269-270 A low-temperature origin for the planetesimals that formed Jupiter
by Tobias Owen & Paul Mahaffy & H. B. Niemann & Sushil Atreya & Thomas Donahue & Akiva Bar-Nun & Imke de Pater - 270-273 Lithium nucleosynthesis in the Sun inferred from the solar-wind 7Li/6Li ratio
by Marc Chaussidon & François Robert - 273-276 Carbon nanotube intramolecular junctions
by Zhen Yao & Henk W. Ch. Postma & Leon Balents & Cees Dekker - 276-279 Design and synthesis of an exceptionally stable and highly porous metal-organic framework
by Hailian Li & Mohamed Eddaoudi & M. O'Keeffe & O. M. Yaghi - 279-282 Abrupt termination of the 1997–98 El Niño in response to a Madden–Julian oscillation
by Yukari N. Takayabu & Toshio Iguchi & Misako Kachi & Akira Shibata & Hiroshi Kanzawa - 282-285 Combined dynamic and geochemical evidence for convergent melt flow beneath the East Pacific Rise
by Marc Spiegelman & Jennifer R. Reynolds - 286-288 Energetic constraints on the diet of terrestrial carnivores
by Chris Carbone & Georgina M. Mace & S. Craig Roberts & David W. Macdonald - 288-290 Total lipid energy as a proxy for total egg production by fish stocks
by C. Tara Marshall & Nathalia A. Yaragina & Yvan Lambert & Olav S. Kjesbu - 291-294 Use of behavioural stochastic resonance by paddle fish for feeding
by David F. Russell & Lon A. Wilkens & Frank Moss - 294-296 The amygdala modulates prefrontal cortex activity relative to conditioned fear
by René Garcia & Rose-Marie Vouimba & Michel Baudry & Richard F. Thompson - 297-301 Kainate receptors are involved in synaptic plasticity
by Zuner A. Bortolotto & Vernon R. J. Clarke & Caroline M. Delany & Michael C. Parry & Ilse Smolders & Michel Vignes & Ken H. Ho & Peter Miu & Bradford T. Brinton & Robert Fantaske & Ann Ogden & Mary Gates & Paul L. Ornstein & David Lodge & David Bleakman & Graham L. Collingridge - 301-304 Activation of the epithelial Na+ channel (ENaC) requires CFTR Cl- channel function
by M. M. Reddy & M. J. Light & P. M. Quinton - 304-309 Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
by Young-Yun Kong & Ulrich Feige & Iidiko Sarosi & Brad Bolon & Anna Tafuri & Sean Morony & Casey Capparelli & Ji Li & Robin Elliott & Susan McCabe & Thomas Wong & Giuseppe Campagnuolo & Erika Moran & Earl R. Bogoch & Gwyneth Van & Linh T. Nguyen & Pamela S. Ohashi & David L. Lacey & Eleanor Fish & William J. Boyle & Josef M. Penninger - 309-313 The p66shc adaptor protein controls oxidative stress response and life span in mammals
by Enrica Migliaccio & Marco Giorgio & Simonetta Mele & Giuliana Pelicci & Paolo Reboldi & Pier Paolo Pandolfi & Luisa Lanfrancone & Pier Giuseppe Pelicci - 313-320 Structural insights into phosphoinositide 3-kinase catalysis and signalling
by Edward H. Walker & Olga Perisic & Christian Ried & Len Stephens & Roger L. Williams - 320-322 Sustained oscillations in living cells
by Sune Danø & Preben Graae Sørensen & Finn Hynne - 323-325 A ribozyme that lacks cytidine
by Jeff Rogers & Gerald F. Joyce
November 1999, Volume 402, Issue 6758
- 3-3 Career choices for scientists: an introduction
by Helen Gavaghan - 109-109 Australia ‘tops per capita emissions’
by Peter Pockley - 109-110 US universities find that demand for botanists exceeds supply
by Rex Dalton - 110-110 Publishing group offers peer review on PubMed Central
by Declan Butler - 110-110 Ukraine denies arresting biologist
by Natasha Loder - 111-111 Cambridge, UK, hopes MIT magic will work on joint institute
by Colin Macilwain - 111-111 Daresbury senses victory in battle for UK synchrotron
by Natasha Loder & Heather McCabe - 112-112 Race is on to find successor to Varmus at NIH
by Meredith Wadman - 112-112 Surprise boost for stem-cell work
by Colin Macilwain - 113-113 University debate boils over in Australia
by Peter Pockley - 113-114 German scientists must repay fees
by Quirin Schiermeier - 114-114 Israel shuts four ‘incubators’ for high-tech companies
by Haim Watzman - 114-114 $2m ransom sought for kidnapped ecologists
by Carl Levitin - 115-115 Publishers map out a way forward in response to free online archives
by Declan Butler - 118-118 Parents need catch-up courses to boost careers
by Wendy Powell - 118-118 Lacking cover
by Vani Kalyanaraman - 118-118 Survey confirms fears about licensing of genetic tests
by Anna Schissel & Jon F. Merz & Mildred K. Cho - 119-120 Lessons in molecular gymnastics
by Philip Ball - 120-121 Evolutionary play on maternal behaviour
by Kristen Hawkes - 121-121 Rocks of the ages
by Robert W. Buddemeier - 122-122 Growing old in Germany
by John Grimley Evans - 123-123 Dark on a light subject
by Brian Pippard - 125-125 Homo sapiens declared extinct
by Bruce Sterling - 127-128 Survival of the weakest
by Erik Asphaug - 128-129 Policing rogue genes
by Rueyling Lin & Leon Avery - 131-132 Distorting sex ratios
by Keith R. Willison - 132-133 Through a glass, lightly
by A. Lindsay Greer - 133-135 Dual control of mitotic exit
by Susanne Prinz & Angelika Amon - 135-136 Knocking out nodules
by Herman P. Spaink - 136-136 Asteroidal defence
by David Jones - 137-138 Motherhood improves learning and memory
by Craig H. Kinsley & Lisa Madonia & Gordon W. Gifford & Kara Tureski & Garrett R. Griffin & Catherine Lowry & Jamison Williams & Jennifer Collins & Heather McLearie & Kelly G. Lambert - 138-138 Fractal modes in unstable resonators
by G. P. Karman & G. S. McDonald & G. H. C. New & J. P. Woerdman - 139-139 Seed germination in rainforest fragments
by Emilio M. Bruna - 139-140 Dichromatism in macaque monkeys
by Akishi Onishi & Satoshi Koike & Miki Ida & Hiroo Imai & Yoshinori Shichida & Osamu Takenaka & Akitoshi Hanazawa & Hidehiko Konatsu & Akichika Mikami & Shunji Goto & Bambang Suryobrotoq & Kenji Kitahara & Tetsuo Yamamori - 141-146 A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance
by Bernhard G. Herrmann & Birgit Koschorz & Karin Wertz & K. John McLaughlin & Andreas Kispert - 147-154 Identification of in vivo substrates of the chaperonin GroEL
by Walid A. Houry & Dmitrij Frishman & Christoph Eckerskorn & Friedrich Lottspeich & F. Ulrich Hartl - 155-157 Compaction as the origin of the unusual craters on the asteroid Mathilde
by Kevin R. Housen & Keith A. Holsapple & Michael E. Voss - 157-160 Spatial sampling of crystal electrons by in-flight annihilation of fast positrons
by A. W. Hunt & D. B. Cassidy & F. A. Selim & R. Haakenaasen & T. E. Cowan & R. H. Howell & K. G. Lynn & J. A. Golovchenko - 160-162 Diffusion mechanisms in metallic supercooled liquids and glasses
by X.-P. Tang & Ulrich Geyer & Ralf Busch & William L. Johnson & Yue Wu - 162-165 Diamond formation by thermal activation of graphite
by A. V. Palnichenko & A. M. Jonas & J.-C. Charlier & A. S. Aronin & J.-P. Issi - 165-167 Modulation of cadmium uptake in phytoplankton by seawater CO2 concentration
by Jay T. Cullen & Todd W. Lane & François M. M. Morel & Robert M. Sherrell - 167-170 Influence of NOx emissions from ships on tropospheric photochemistry and climate
by Mark G. Lawrence & Paul J. Crutzen - 170-173 A polar vortex in the Earth's core
by Peter Olson & Jonathan Aurnou - 173-176 The insidious effect of diatoms on copepod reproduction
by A. Miralto & G. Barone & G. Romano & S. A. Poulet & A. Ianora & G. L. Russo & I. Buttino & G. Mazzarella & M. Laabir & M. Cabrini & M. G. Giacobbe - 176-178 Signal but not noise changes with perceptual learning
by J. Gold & P. J. Bennett & A. B. Sekuler - 179-181 Conflict monitoring versus selection-for-action in anterior cingulate cortex
by Matthew Botvinick & Leigh E. Nystrom & Kate Fissell & Cameron S. Carter & Jonathan D. Cohen - 181-184 Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
by Lutz Hein & John D. Altman & Brian K. Kobilka - 184-187 Rapid gating and anion permeability of an intracellular aquaporin
by Masato Yasui & Akihiro Hazama & Tae-Hwan Kwon & Søren Nielsen & Wm. B. Guggino & Peter Agre - 187-191 Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
by Guo-Liang Xu & Timothy H. Bestor & Déborah Bourc'his & Chih-Lin Hsieh & Niels Tommerup & Merete Bugge & Maj Hulten & Xiaoyan Qu & James J. Russo & Evani Viegas-Péquignot - 191-195 A plant regulator controlling development of symbiotic root nodules
by Leif Schauser & Andreas Roussis & Jiri Stiller & Jens Stougaard - 195-199 CaMKII regulates the density of central glutamatergic synapses in vivo
by Christopher Rongo & Joshua M. Kaplan - 199-203 Diverse behavioural defects caused by mutations in Caenorhabditis elegans unc-43 CaM Kinase II
by David J. Reiner & Elizabeth M. Newton & Hong Tian & James H. Thomas - 203-207 APCCdc20 promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5
by Masaki Shirayama & Attila Tóth & Marta Gálová & Kim Nasmyth - 207-210 The RNA splicing factor hSlu7 is required for correct 3′ splice-site choice
by Katrin Chua & Robin Reed - 213-215 From bench to bedside… research makes the translational transition
by Brendan Horton - 215-215 Clinical research in practice
by Diane Gershon - 215-216 Improving the plight of the physician–scientist in the US
by Diane Gershon
November 1999, Volume 402, Issue 6757
- 3-3 South Africa says AIDS drug ‘toxic’
by Michael Cherry - 3-4 Life science facilities in crisis as Brussels switches off funding
by Declan Butler - 4-4 Framework funding ban hits mouse mutant archive
by Alison Abbott - 5-5 Silicon pioneer funds biomedical engineering centre
by Rex Dalton - 5-5 Californian universities scrap hospitals merger
by Rex Dalton - 6-6 Protests grow over interrogation of Ukraine scientists
by Natasha Loder - 6-6 NIH panel to limit secrecy on gene therapy
by Meredith Wadman - 7-7 NASA relativity probe facing costly delay
by Tony Reichhardt - 7-8 Threats to US primate researchers
by Steve Nadis - 8-8 Japan plans ethics guidelines
by Asako Saegusa - 8-8 French scientists resign from Allègre's advisory council
by Heather McCabe - 9-9 Providing support and a voice for Europe's young researchers
by Natasha Loder - 12-12 University becomes political football
by Georges Dreyfus - 12-12 Europe must grant crucial funds for biological research
by Michael Ashburner - 13-13 Making no sense, making money
by Alison Mitchell - 13-14 Making sense, making money
by Norman Myers - 14-15 Condensed physics matters
by Philip W. Anderson - 15-16 Simple twists of fate
by Jonathan Hodgkin