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The genetic program for cartilage development has deep homology within Bilateria

Author

Listed:
  • Oscar A. Tarazona

    (Howard Hughes Medical Institute, UF Genetics Institute, University of Florida
    University of Florida)

  • Leslie A. Slota

    (University of Florida College of Medicine)

  • Davys H. Lopez

    (University of Florida College of Medicine)

  • GuangJun Zhang

    (University of Florida
    † Present address: Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, 625 Harrison Street, West Lafayette, Indiana 47907, USA.)

  • Martin J. Cohn

    (Howard Hughes Medical Institute, UF Genetics Institute, University of Florida
    University of Florida
    University of Florida College of Medicine)

Abstract

Vertebrate and invertebrate cartilage share structural and biochemical properties, and their development is controlled by a highly conserved genetic circuit, suggesting that a deeply homologous mechanism underlies the parallel evolution of cartilage in Bilateria.

Suggested Citation

  • Oscar A. Tarazona & Leslie A. Slota & Davys H. Lopez & GuangJun Zhang & Martin J. Cohn, 2016. "The genetic program for cartilage development has deep homology within Bilateria," Nature, Nature, vol. 533(7601), pages 86-89, May.
    • Handle: RePEc:nat:nature:v:533:y:2016:i:7601:d:10.1038_nature17398
    DOI: 10.1038/nature17398
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