IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v533y2016i7603d10.1038_nature17662.html
   My bibliography  Save this article

An obligatory role for neurotensin in high-fat-diet-induced obesity

Author

Listed:
  • Jing Li

    (University of Kentucky
    Markey Cancer Center, University of Kentucky)

  • Jun Song

    (University of Kentucky
    Markey Cancer Center, University of Kentucky)

  • Yekaterina Y. Zaytseva

    (Markey Cancer Center, University of Kentucky
    University of Kentucky)

  • Yajuan Liu

    (Markey Cancer Center, University of Kentucky)

  • Piotr Rychahou

    (University of Kentucky
    Markey Cancer Center, University of Kentucky)

  • Kai Jiang

    (Markey Cancer Center, University of Kentucky)

  • Marlene E. Starr

    (University of Kentucky)

  • Ji Tae Kim

    (University of Kentucky
    Markey Cancer Center, University of Kentucky)

  • Jennifer W. Harris

    (University of Kentucky
    Markey Cancer Center, University of Kentucky)

  • Frederique B. Yiannikouris

    (University of Kentucky)

  • Wendy S. Katz

    (University of Kentucky)

  • Peter M. Nilsson

    (Lund University
    Skåne University Hospital)

  • Marju Orho-Melander

    (Lund University)

  • Jing Chen

    (University of Kentucky
    Center for Structural Biology, University of Kentucky)

  • Haining Zhu

    (University of Kentucky
    Center for Structural Biology, University of Kentucky)

  • Timothy Fahrenholz

    (Markey Cancer Center, University of Kentucky
    University of Kentucky
    Center for Environmental and Systems Biochemistry, University of Kentucky)

  • Richard M. Higashi

    (Markey Cancer Center, University of Kentucky
    University of Kentucky
    Center for Environmental and Systems Biochemistry, University of Kentucky)

  • Tianyan Gao

    (Markey Cancer Center, University of Kentucky
    University of Kentucky)

  • Andrew J. Morris

    (Gill Heart Institute, University of Kentucky and Lexington Veterans Affairs Medical Center)

  • Lisa A. Cassis

    (University of Kentucky)

  • Teresa W. -M. Fan

    (Markey Cancer Center, University of Kentucky
    University of Kentucky
    Center for Environmental and Systems Biochemistry, University of Kentucky)

  • Heidi L. Weiss

    (Markey Cancer Center, University of Kentucky
    University of Kentucky)

  • Paul R. Dobner

    (University of Massachusetts Medical School)

  • Olle Melander

    (Lund University
    Skåne University Hospital)

  • Jianhang Jia

    (Markey Cancer Center, University of Kentucky
    University of Kentucky)

  • B. Mark Evers

    (University of Kentucky
    Markey Cancer Center, University of Kentucky)

Abstract

Neurotensin, a peptide expressed in the enteroendocrine cells of the small intestine that is released upon fat ingestion, is shown to increase fatty acid absorption, with neurotensin-deficient mice being protected from obesity induced by a high-fat diet.

Suggested Citation

  • Jing Li & Jun Song & Yekaterina Y. Zaytseva & Yajuan Liu & Piotr Rychahou & Kai Jiang & Marlene E. Starr & Ji Tae Kim & Jennifer W. Harris & Frederique B. Yiannikouris & Wendy S. Katz & Peter M. Nilss, 2016. "An obligatory role for neurotensin in high-fat-diet-induced obesity," Nature, Nature, vol. 533(7603), pages 411-415, May.
    • Handle: RePEc:nat:nature:v:533:y:2016:i:7603:d:10.1038_nature17662
    DOI: 10.1038/nature17662
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature17662
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature17662?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Maximilian Tremmel & Ulf-G. Gerdtham & Peter M. Nilsson & Sanjib Saha, 2017. "Economic Burden of Obesity: A Systematic Literature Review," IJERPH, MDPI, vol. 14(4), pages 1-18, April.
    2. Chuanxin Zhong & Nanxi Li & Shengzheng Wang & Dijie Li & Zhihua Yang & Lin Du & Guangxin Huang & Haitian Li & Wing Sze Yeung & Shan He & Shuting Ma & Zhuqian Wang & Hewen Jiang & Huarui Zhang & Zhangh, 2024. "Targeting osteoblastic 11β-HSD1 to combat high-fat diet-induced bone loss and obesity," Nature Communications, Nature, vol. 15(1), pages 1-18, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:533:y:2016:i:7603:d:10.1038_nature17662. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.