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Content
January 2018, Volume 553, Issue 7686
- 59-62 Photonic topological boundary pumping as a probe of 4D quantum Hall physics
by Oded Zilberberg & Sheng Huang & Jonathan Guglielmon & Mohan Wang & Kevin P. Chen & Yaacov E. Kraus & Mikael C. Rechtsman - 63-67 One-pot growth of two-dimensional lateral heterostructures via sequential edge-epitaxy
by Prasana K. Sahoo & Shahriar Memaran & Yan Xin & Luis Balicas & Humberto R. Gutiérrez - 68-72 Perovskite nickelates as electric-field sensors in salt water
by Zhen Zhang & Derek Schwanz & Badri Narayanan & Michele Kotiuga & Joseph A. Dura & Mathew Cherukara & Hua Zhou & John W. Freeland & Jiarui Li & Ronny Sutarto & Feizhou He & Chongzhao Wu & Jiaxin Zhu & Yifei Sun & Koushik Ramadoss & Stephen S. Nonnenmann & Nanfang Yu & Riccardo Comin & Karin M. Rabe & Subramanian K. R. S. Sankaranarayanan & Shriram Ramanathan - 73-76 Unexpectedly large impact of forest management and grazing on global vegetation biomass
by Karl-Heinz Erb & Thomas Kastner & Christoph Plutzar & Anna Liza S. Bais & Nuno Carvalhais & Tamara Fetzel & Simone Gingrich & Helmut Haberl & Christian Lauk & Maria Niedertscheider & Julia Pongratz & Martin Thurner & Sebastiaan Luyssaert - 77-81 Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host
by David Palesch & Steven E. Bosinger & Gregory K. Tharp & Thomas H. Vanderford & Mirko Paiardini & Ann Chahroudi & Zachary P. Johnson & Frank Kirchhoff & Beatrice H. Hahn & Robert B. Norgren & Nirav B. Patel & Donald L. Sodora & Reem A. Dawoud & Caro-Beth Stewart & Sara M. Seepo & R. Alan Harris & Yue Liu & Muthuswamy Raveendran & Yi Han & Adam English & Gregg W. C. Thomas & Matthew W. Hahn & Lenore Pipes & Christopher E. Mason & Donna M. Muzny & Richard A. Gibbs & Daniel Sauter & Kim Worley & Jeffrey Rogers & Guido Silvestri - 82-85 MicroRNAs from the parasitic plant Cuscuta campestris target host messenger RNAs
by Saima Shahid & Gunjune Kim & Nathan R. Johnson & Eric Wafula & Feng Wang & Ceyda Coruh & Vivian Bernal-Galeano & Tamia Phifer & Claude W. dePamphilis & James H. Westwood & Michael J. Axtell - 86-90 Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts
by Raymond W. Bourdeau & Audrey Lee-Gosselin & Anupama Lakshmanan & Arash Farhadi & Sripriya Ravindra Kumar & Suchita P. Nety & Mikhail G. Shapiro - 91-95 Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
by Jinfang Zhang & Xia Bu & Haizhen Wang & Yasheng Zhu & Yan Geng & Naoe Taira Nihira & Yuyong Tan & Yanpeng Ci & Fei Wu & Xiangpeng Dai & Jianping Guo & Yu-Han Huang & Caoqi Fan & Shancheng Ren & Yinghao Sun & Gordon J. Freeman & Piotr Sicinski & Wenyi Wei - 96-100 Senescence-associated reprogramming promotes cancer stemness
by Maja Milanovic & Dorothy N. Y. Fan & Dimitri Belenki & J. Henry M. Däbritz & Zhen Zhao & Yong Yu & Jan R. Dörr & Lora Dimitrova & Dido Lenze & Ines A. Monteiro Barbosa & Marco A. Mendoza-Parra & Tamara Kanashova & Marlen Metzner & Katharina Pardon & Maurice Reimann & Andreas Trumpp & Bernd Dörken & Johannes Zuber & Hinrich Gronemeyer & Michael Hummel & Gunnar Dittmar & Soyoung Lee & Clemens A. Schmitt - 101-105 Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
by Stephen C. Mack & Kristian W. Pajtler & Lukas Chavez & Konstantin Okonechnikov & Kelsey C. Bertrand & Xiuxing Wang & Serap Erkek & Alexander Federation & Anne Song & Christine Lee & Xin Wang & Laura McDonald & James J. Morrow & Alina Saiakhova & Patrick Sin-Chan & Qiulian Wu & Kulandaimanuvel Antony Michaelraj & Tyler E. Miller & Christopher G. Hubert & Marina Ryzhova & Livia Garzia & Laura Donovan & Stephen Dombrowski & Daniel C. Factor & Betty Luu & Claudia L. L. Valentim & Ryan C. Gimple & Andrew Morton & Leo Kim & Briana C. Prager & John J. Y. Lee & Xiaochong Wu & Jennifer Zuccaro & Yuan Thompson & Borja L. Holgado & Jüri Reimand & Susan Q. Ke & Adam Tropper & Sisi Lai & Senthuran Vijayarajah & Sylvia Doan & Vaidehi Mahadev & Ana Fernandez Miñan & Susanne N. Gröbner & Matthias Lienhard & Marc Zapatka & Zhiqin Huang & Kenneth D. Aldape & Angel M. Carcaboso & Peter J. Houghton & Stephen T. Keir & Till Milde & Hendrik Witt & Yan Li & Chao-Jun Li & Xiu-Wu Bian & David T. W. Jones & Ian Scott & Sheila K. Singh & Annie Huang & Peter B. Dirks & Eric Bouffet & James E. Bradner & Vijay Ramaswamy & Nada Jabado & James T. Rutka & Paul A. Northcott & Mathieu Lupien & Peter Lichter & Andrey Korshunov & Peter C. Scacheri & Stefan M. Pfister & Marcel Kool & Michael D. Taylor & Jeremy N. Rich - 106-110 Structure of the glucagon receptor in complex with a glucagon analogue
by Haonan Zhang & Anna Qiao & Linlin Yang & Ned Van Eps & Klaus S. Frederiksen & Dehua Yang & Antao Dai & Xiaoqing Cai & Hui Zhang & Cuiying Yi & Can Cao & Lingli He & Huaiyu Yang & Jesper Lau & Oliver P. Ernst & Michael A. Hanson & Raymond C. Stevens & Ming-Wei Wang & Steffen Reedtz-Runge & Hualiang Jiang & Qiang Zhao & Beili Wu - 111-114 Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727
by Nathan Robertson & Mathieu Rappas & Andrew S. Doré & Jason Brown & Giovanni Bottegoni & Markus Koglin & Julie Cansfield & Ali Jazayeri & Robert M. Cooke & Fiona H. Marshall - 115-116 The research hardware in your video-game system
by Anna Nowogrodzki - 117-119 Put it on camera: How to get into scientific film- and video-making
by Roberta Kwok - 122-122 Universal Parking, Inc
by James Anderson
December 2017, Volume 552, Issue 7685
- 61-61 Cancer immunotherapy
by Eric Bender - 62-63 The quest to extend the reach of checkpoint inhibitors in lung cancer
by Karen Weintraub - 64-66 Attack of the killer clones
by Megan Scudellari - 67-69 The benefits of immunotherapy combinations
by Charles Schmidt - 70-71 Cancer immunotherapy research round-up
by Joana Osório - 72-73 Making cancer immunotherapy a surer bet
by Michael Eisenstein - 74-75 The struggle to do no harm in clinical trials
by Charles Schmidt - 76-77 Calling cancer’s bluff with neoantigen vaccines
by Sarah DeWeerdt - 78-78 Drug pricing should depend on shared values
by Scott Ramsey - 107-109 A smart place to work
by Brett Davis - 293-293 Peer reviewers need more nurturing
by Richard Catlow - 299-300 Rescued radar maps reveal Antarctica's past
by Alexandra Witze - 300-301 Gene editing staves off deafness in mice
by Heidi Ledford - 301-302 Could Bitcoin technology help science?
by Andy Extance - 302-302 South Korean scientists eager for reactor restart
by David Cyranoski - 304-307 2017 in news: The science events that shaped the year
by Ewen Callaway & Davide Castelvecchi & David Cyranoski & Elizabeth Gibney & Heidi Ledford & Jane J. Lee & Lauren Morello & Nicky Phillips & Quirin Schiermeier & Jeff Tollefson & Richard Van Noorden & Alexandra Witze - 308-313 2017 in pictures: The best science images of the year
by Nisha Gaind - 315-324 Nature’s 10
by Heidi Ledford & Davide Castelvecchi & Elie Dolgin & Sara Reardon & Elizabeth Gibney & Nicky Phillips & Alexandra Witze - 325-328 The case for technology investments in the environment
by Lucas N. Joppa - 329-333 Science fiction when the future is now
by Lauren Beukes & Kim Stanley Robinson & Ken Liu & Hannu Rajaniemi & Alastair Reynolds & Aliette de Bodard - 334-334 Train artificial intelligence to be fair to farming
by Yu-Pin Lin & Joy R. Petway & Josef Settele - 334-334 India and Pakistan need to collaborate against pollution
by Muhammad Usman & Abdul Wakeel & Muhammad Farooq - 334-334 Parasites’ rights gaining ground
by Donald A. Windsor - 334-334 A checklist to protect human rights in artificial-intelligence research
by Sumathy Ramesh - 334-334 Why eavesdropping in open-plan spaces is good for your research
by Volker Heine - 336-337 Energy from thin air
by Don A. Cowan & Thulani P. Makhalanyane - 337-339 The origins of memory T cells
by Kyla D. Omilusik & Ananda W. Goldrath - 339-340 Martian water stored underground
by Tomohiro Usui - 340-342 Tumour lymph vessels boost immunotherapy
by Christine Moussion & Shannon J. Turley - 342-343 Specks of insight into Alzheimer’s disease
by Richard M. Ransohoff - 347-354 Synthesis of E- and Z-trisubstituted alkenes by catalytic cross-metathesis
by Thach T. Nguyen & Ming Joo Koh & Tyler J. Mann & Richard R. Schrock & Amir H. Hoveyda - 355-361 Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
by Carmen Venegas & Sathish Kumar & Bernardo S. Franklin & Tobias Dierkes & Rebecca Brinkschulte & Dario Tejera & Ana Vieira-Saecker & Stephanie Schwartz & Francesco Santarelli & Markus P. Kummer & Angelika Griep & Ellen Gelpi & Michael Beilharz & Dietmar Riedel & Douglas T. Golenbock & Matthias Geyer & Jochen Walter & Eicke Latz & Michael T. Heneka - 362-367 Origin and differentiation of human memory CD8 T cells after vaccination
by Rama S. Akondy & Mark Fitch & Srilatha Edupuganti & Shu Yang & Haydn T. Kissick & Kelvin W. Li & Ben A. Youngblood & Hossam A. Abdelsamed & Donald J. McGuire & Kristen W. Cohen & Gabriela Alexe & Shashi Nagar & Megan M. McCausland & Satish Gupta & Pramila Tata & W. Nicholas Haining & M. Juliana McElrath & David Zhang & Bin Hu & William J. Greenleaf & Jorg J. Goronzy & Mark J. Mulligan & Marc Hellerstein & Rafi Ahmed - 368-373 Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40
by Haijuan Yang & Xiaolu Jiang & Buren Li & Hyo J. Yang & Meredith Miller & Angela Yang & Ankita Dhar & Nikola P. Pavletich - 374-377 Blazar spectral variability as explained by a twisted inhomogeneous jet
by C. M. Raiteri & M. Villata & J. A. Acosta-Pulido & I. Agudo & A. A. Arkharov & R. Bachev & G. V. Baida & E. Benítez & G. A. Borman & W. Boschin & V. Bozhilov & M. S. Butuzova & P. Calcidese & M. I. Carnerero & D. Carosati & C. Casadio & N. Castro-Segura & W.-P. Chen & G. Damljanovic & F. D’Ammando & A. Di Paola & J. Echevarría & N. V. Efimova & Sh. A. Ehgamberdiev & C. Espinosa & A. Fuentes & A. Giunta & J. L. Gómez & T. S. Grishina & M. A. Gurwell & D. Hiriart & H. Jermak & B. Jordan & S. G. Jorstad & M. Joshi & E. N. Kopatskaya & K. Kuratov & O. M. Kurtanidze & S. O. Kurtanidze & A. Lähteenmäki & V. M. Larionov & E. G. Larionova & L. V. Larionova & C. Lázaro & C. S. Lin & M. P. Malmrose & A. P. Marscher & K. Matsumoto & B. McBreen & R. Michel & B. Mihov & M. Minev & D. O. Mirzaqulov & A. A. Mokrushina & S. N. Molina & J. W. Moody & D. A. Morozova & S. V. Nazarov & M. G. Nikolashvili & J. M. Ohlert & D. N. Okhmat & E. Ovcharov & F. Pinna & T. A. Polakis & C. Protasio & T. Pursimo & F. J. Redondo-Lorenzo & N. Rizzi & G. Rodriguez-Coira & K. Sadakane & A. C. Sadun & M. R. Samal & S. S. Savchenko & E. Semkov & B. A. Skiff & L. Slavcheva-Mihova & P. S. Smith & I. A. Steele & A. Strigachev & J. Tammi & C. Thum & M. Tornikoski & Yu. V. Troitskaya & I. S. Troitsky & A. A. Vasilyev & O. Vince - 378-381 A brief visit from a red and extremely elongated interstellar asteroid
by Karen J. Meech & Robert Weryk & Marco Micheli & Jan T. Kleyna & Olivier R. Hainaut & Robert Jedicke & Richard J. Wainscoat & Kenneth C. Chambers & Jacqueline V. Keane & Andreea Petric & Larry Denneau & Eugene Magnier & Travis Berger & Mark E. Huber & Heather Flewelling & Chris Waters & Eva Schunova-Lilly & Serge Chastel - 382-385 Measurement of electrons from albedo neutron decay and neutron density in near-Earth space
by Xinlin Li & Richard Selesnick & Quintin Schiller & Kun Zhang & Hong Zhao & Daniel N. Baker & Michael A. Temerin - 386-390 Discovery of a big void in Khufu’s Pyramid by observation of cosmic-ray muons
by Kunihiro Morishima & Mitsuaki Kuno & Akira Nishio & Nobuko Kitagawa & Yuta Manabe & Masaki Moto & Fumihiko Takasaki & Hirofumi Fujii & Kotaro Satoh & Hideyo Kodama & Kohei Hayashi & Shigeru Odaka & Sébastien Procureur & David Attié & Simon Bouteille & Denis Calvet & Christopher Filosa & Patrick Magnier & Irakli Mandjavidze & Marc Riallot & Benoit Marini & Pierre Gable & Yoshikatsu Date & Makiko Sugiura & Yasser Elshayeb & Tamer Elnady & Mustapha Ezzy & Emmanuel Guerriero & Vincent Steiger & Nicolas Serikoff & Jean-Baptiste Mouret & Bernard Charlès & Hany Helal & Mehdi Tayoubi - 391-394 The divergent fates of primitive hydrospheric water on Earth and Mars
by Jon Wade & Brendan Dyck & Richard M. Palin & James D. P. Moore & Andrew J. Smye - 395-399 Synchrotron scanning reveals amphibious ecomorphology in a new clade of bird-like dinosaurs
by Andrea Cau & Vincent Beyrand & Dennis F. A. E. Voeten & Vincent Fernandez & Paul Tafforeau & Koen Stein & Rinchen Barsbold & Khishigjav Tsogtbaatar & Philip J. Currie & Pascal Godefroit - 400-403 Atmospheric trace gases support primary production in Antarctic desert surface soil
by Mukan Ji & Chris Greening & Inka Vanwonterghem & Carlo R. Carere & Sean K. Bay & Jason A. Steen & Kate Montgomery & Thomas Lines & John Beardall & Josie van Dorst & Ian Snape & Matthew B. Stott & Philip Hugenholtz & Belinda C. Ferrari - 404-409 Effector CD8 T cells dedifferentiate into long-lived memory cells
by Ben Youngblood & J. Scott Hale & Haydn T. Kissick & Eunseon Ahn & Xiaojin Xu & Andreas Wieland & Koichi Araki & Erin E. West & Hazem E. Ghoneim & Yiping Fan & Pranay Dogra & Carl W. Davis & Bogumila T. Konieczny & Rustom Antia & Xiaodong Cheng & Rafi Ahmed - 410-414 Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic
by Kangmin He & Robert Marsland III & Srigokul Upadhyayula & Eli Song & Song Dang & Benjamin R. Capraro & Weiming Wang & Wesley Skillern & Raphael Gaudin & Minghe Ma & Tom Kirchhausen - 415-420 Evolution of a designed protein assembly encapsulating its own RNA genome
by Gabriel L. Butterfield & Marc J. Lajoie & Heather H. Gustafson & Drew L. Sellers & Una Nattermann & Daniel Ellis & Jacob B. Bale & Sharon Ke & Garreck H. Lenz & Angelica Yehdego & Rashmi Ravichandran & Suzie H. Pun & Neil P. King & David Baker - 421-425 Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
by Cristina Paulino & Valeria Kalienkova & Andy K. M. Lam & Yvonne Neldner & Raimund Dutzler - 426-429 Cryo-EM structures of the TMEM16A calcium-activated chloride channel
by Shangyu Dang & Shengjie Feng & Jason Tien & Christian J. Peters & David Bulkley & Marco Lolicato & Jianhua Zhao & Kathrin Zuberbühler & Wenlei Ye & Lijun Qi & Tingxu Chen & Charles S. Craik & Yuh Nung Jan & Daniel L. Minor & Yifan Cheng & Lily Yeh Jan - 430-430 Correction: Corrigendum: Mega-evolutionary dynamics of the adaptive radiation of birds
by Christopher R. Cooney & Jen A. Bright & Elliot J. R. Capp & Angela M. Chira & Emma C. Hughes & Christopher J. A. Moody & Lara O. Nouri & Zoë K. Varley & Gavin H. Thomas - 430-430 Erratum: Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
by Shabnam Shalapour & Xue-Jia Lin & Ingmar N. Bastian & John Brain & Alastair D. Burt & Alexander A. Aksenov & Alison F. Vrbanac & Weihua Li & Andres Perkins & Takaji Matsutani & Zhenyu Zhong & Debanjan Dhar & Jose A. Navas-Molina & Jun Xu & Rohit Loomba & Michael Downes & Ruth T. Yu & Ronald M. Evans & Pieter C. Dorrestein & Rob Knight & Christopher Benner & Quentin M. Anstee & Michael Karin - 430-430 Correction: Corrigendum: RNA m6A methylation regulates the ultraviolet-induced DNA damage response
by Yang Xiang & Benoit Laurent & Chih-Hung Hsu & Sigrid Nachtergaele & Zhike Lu & Wanqiang Sheng & Chuanyun Xu & Hao Chen & Jian Ouyang & Siqing Wang & Dominic Ling & Pang-Hung Hsu & Lee Zou & Ashwini Jambhekar & Chuan He & Yang Shi - 431-432 Top ten tips to kick-start your career in 2018
by Chris Woolston - 434-434 The coupon
by Judy Helfrich
December 2017, Volume 552, Issue 7684
- 49-49 Spinal-cord injury: spurring regrowth
by David Holmes - 50-51 Repairing the neural highway
by David Holmes - 53-55 Chile’s chance to embrace science for the twenty-first century
by Aleszu Bajak - 57-59 New tricks from old dogs join the fight against ageing
by Neil Savage - 149-149 Zimbabwe’s new government must commit to science
by Dexter Tagwireyi - 155-156 Nine researchers sue University of Rochester over sexual-harassment allegations
by Alexandra Witze - 156-157 Tasmanian tiger genome offers clues to its extinction
by Ewen Callaway - 157-158 Acupuncture in cancer study reignites debate about controversial technique
by Jo Marchant - 158-159 US graduate students in uproar over proposed tax hike
by Helen Shen - 159-160 Argentinian geoscientist faces criminal charges over glacier survey
by Jeff Tollefson & Emiliano Rodríguez Mega - 162-164 The science that’s never been cited
by Richard Van Noorden - 165-167 Deploy vaccines to fight superbugs
by Rino Rappuoli & David E. Bloom & Steve Black - 168-170 Five priorities for weather and climate research
by Øystein Hov & Deon Terblanche & Gregory Carmichael & Sarah Jones & Paolo M. Ruti & Oksana Tarasova - 172-173 Planetariums and the rise of spectacular science
by Marek Kukula - 173-173 A manifesto for slow science, the biology of personal space, and an intimate look at the neuroscience of food: Books in brief
by Barbara Kiser - 174-174 Lyme disease laid bare
by James G. Logan - 175-175 Medical legacy of sanctions in Iran
by Reza Heidari & Mostafa Akbariqomi & Gholamreza Tavoosidana - 175-175 How to spare half a planet
by Andrew Balmford & Rhys Green - 175-175 Snow leopard conservation status is spot on
by Tom McCarthy - 175-175 Standardize future device connections for computers
by Ricardo Borges - 175-175 Pricing not enough for deep carbon cuts
by Michael Mehling & Endre Tvinnereim - 176-176 Ronald Breslow (1931–2017)
by Virginia W. Cornish - 178-179 Early embryos kept in check
by Julien G. Dumortier & Jean-Léon Maître - 179-180 Stellar cannibalism in fits and starts
by Thomas Marsh - 180-181 A dark side to omega-3 fatty acids
by Keisuke Yanagida & Timothy Hla - 182-183 Longer life through an odd Pol enzyme
by Bruce A. Edgar & Savraj S. Grewal - 183-184 Antarctic ice dynamics in warm climates
by Sarah Greenwood - 184-185 Viruses hijack a long non-coding RNA
by Nicholas S. Heaton & Bryan R. Cullen - 187-193 Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity
by Vincenzo Sorrentino & Mario Romani & Laurent Mouchiroud & John S. Beck & Hongbo Zhang & Davide D’Amico & Norman Moullan & Francesca Potenza & Adrien W. Schmid & Solène Rietsch & Scott E. Counts & Johan Auwerx - 194-199 Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
by Zdenek Skrott & Martin Mistrik & Klaus Kaae Andersen & Søren Friis & Dusana Majera & Jan Gursky & Tomas Ozdian & Jirina Bartkova & Zsofia Turi & Pavel Moudry & Marianne Kraus & Martina Michalova & Jana Vaclavkova & Petr Dzubak & Ivo Vrobel & Pavla Pouckova & Jindrich Sedlacek & Andrea Miklovicova & Anne Kutt & Jing Li & Jana Mattova & Christoph Driessen & Q. Ping Dou & Jørgen Olsen & Marian Hajduch & Boris Cvek & Raymond J. Deshaies & Jiri Bartek - 200-204 Electron cryo-microscopy structure of a human TRPM4 channel
by Paige A. Winkler & Yihe Huang & Weinan Sun & Juan Du & Wei Lü - 205-209 Structures of the calcium-activated, non-selective cation channel TRPM4
by Jiangtao Guo & Ji She & Weizhong Zeng & Qingfeng Chen & Xiao-chen Bai & Youxing Jiang - 210-213 Magnetically gated accretion in an accreting ‘non-magnetic’ white dwarf
by S. Scaringi & T. J. Maccarone & C. D’Angelo & C. Knigge & P. J. Groot - 214-218 An electric-eel-inspired soft power source from stacked hydrogels
by Thomas B. H. Schroeder & Anirvan Guha & Aaron Lamoureux & Gloria VanRenterghem & David Sept & Max Shtein & Jerry Yang & Michael Mayer - 219-224 Force loading explains spatial sensing of ligands by cells
by Roger Oria & Tina Wiegand & Jorge Escribano & Alberto Elosegui-Artola & Juan Jose Uriarte & Cristian Moreno-Pulido & Ilia Platzman & Pietro Delcanale & Lorenzo Albertazzi & Daniel Navajas & Xavier Trepat & José Manuel García-Aznar & Elisabetta Ada Cavalcanti-Adam & Pere Roca-Cusachs - 225-229 Initiation and long-term instability of the East Antarctic Ice Sheet
by Sean P. S. Gulick & Amelia E. Shevenell & Aleksandr Montelli & Rodrigo Fernandez & Catherine Smith & Sophie Warny & Steven M. Bohaty & Charlotte Sjunneskog & Amy Leventer & Bruce Frederick & Donald D. Blankenship - 230-234 Large emissions from floodplain trees close the Amazon methane budget
by Sunitha R. Pangala & Alex Enrich-Prast & Luana S. Basso & Roberta Bittencourt Peixoto & David Bastviken & Edward R. C. Hornibrook & Luciana V. Gatti & Humberto Marotta & Luana Silva Braucks Calazans & Cassia Mônica Sakuragui & Wanderley Rodrigues Bastos & Olaf Malm & Emanuel Gloor & John Bharat Miller & Vincent Gauci - 235-238 A compositional tipping point governing the mobilization and eruption style of rhyolitic magma
by D. Di Genova & S. Kolzenburg & S. Wiesmaier & E. Dallanave & D. R. Neuville & K. U. Hess & D. B. Dingwell - 239-243 Pluripotent state transitions coordinate morphogenesis in mouse and human embryos
by Marta N. Shahbazi & Antonio Scialdone & Natalia Skorupska & Antonia Weberling & Gaelle Recher & Meng Zhu & Agnieszka Jedrusik & Liani G. Devito & Laila Noli & Iain C. Macaulay & Christa Buecker & Yakoub Khalaf & Dusko Ilic & Thierry Voet & John C. Marioni & Magdalena Zernicka-Goetz - 244-247 Moving beyond microbiome-wide associations to causal microbe identification
by Neeraj K. Surana & Dennis L. Kasper - 248-252 Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy
by Jiong Hu & Sarah Dziumbla & Jihong Lin & Sofia-Iris Bibli & Sven Zukunft & Julian de Mos & Khader Awwad & Timo Frömel & Andreas Jungmann & Kavi Devraj & Zhixing Cheng & Liya Wang & Sascha Fauser & Charles G. Eberhart & Akrit Sodhi & Bruce D. Hammock & Stefan Liebner & Oliver J. Müller & Clemens Glaubitz & Hans-Peter Hammes & Rüdiger Popp & Ingrid Fleming - 253-257 Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours
by J. Justin Milner & Clara Toma & Bingfei Yu & Kai Zhang & Kyla Omilusik & Anthony T. Phan & Dapeng Wang & Adam J. Getzler & Toan Nguyen & Shane Crotty & Wei Wang & Matthew E. Pipkin & Ananda W. Goldrath - 258-262 A non-canonical Notch complex regulates adherens junctions and vascular barrier function
by William J. Polacheck & Matthew L. Kutys & Jinling Yang & Jeroen Eyckmans & Yinyu Wu & Hema Vasavada & Karen K. Hirschi & Christopher S. Chen - 263-267 RNA polymerase III limits longevity downstream of TORC1
by Danny Filer & Maximillian A. Thompson & Vakil Takhaveev & Adam J. Dobson & Ilektra Kotronaki & James W. M. Green & Matthias Heinemann & Jennifer M. A. Tullet & Nazif Alic - 268-272 piRNA-mediated regulation of transposon alternative splicing in the soma and germ line
by Felipe Karam Teixeira & Martyna Okuniewska & Colin D. Malone & Rémi-Xavier Coux & Donald C. Rio & Ruth Lehmann - 273-277 KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
by Yugang Wang & Yusong R. Guo & Ke Liu & Zheng Yin & Rui Liu & Yan Xia & Lin Tan & Peiying Yang & Jong-Ho Lee & Xin-jian Li & David Hawke & Yanhua Zheng & Xu Qian & Jianxin Lyu & Jie He & Dongming Xing & Yizhi Jane Tao & Zhimin Lu - 278-278 Correction: Corrigendum: The 4D nucleome project
by Job Dekker & Andrew S. Belmont & Mitchell Guttman & Victor O. Leshyk & John T. Lis & Stavros Lomvardas & Leonid A. Mirny & Clodagh C. O’Shea & Peter J. Park & Bing Ren & Joan C. Ritland Politz & Jay Shendure & Sheng Zhong - 278-278 Erratum: Probabilistic reanalysis of twentieth-century sea-level rise
by Carling C. Hay & Eric Morrow & Robert E. Kopp & Jerry X. Mitrovica - 278-278 Erratum: Early members of ‘living fossil’ lineage imply later origin of modern ray-finned fishes
by Sam Giles & Guang-Hui Xu & Thomas J. Near & Matt Friedman - 279-281 How museum work can combine research and public engagement
by Amber Dance - 284-284 Fifteen minutes
by Alex Shvartsman
December 2017, Volume 552, Issue 7683
- 5-5 Outsourcing discovery
by Smriti Mallapaty - 7-7 Wanted: academics wise to the needs of government
by Chris Tyler - 10-10 Papers to patents
by Ashish Arora & Sharon Belenzon & Andrea Patacconi - 11-13 Industry links boost research output
by Neil Savage - 13-14 Archaeologists uneasy as Trump shrinks Bears Ears monument lands
by Cally Carswell - 14-15 Huge haul of rare pterosaur eggs excites palaeontologists
by John Pickrell - 14-15 Help wanted: industry seeks science alliances
by Katharine Gammon - 15-16 Bat cave solves mystery of deadly SARS virus — and suggests new outbreak could occur
by David Cyranoski - 16-17 Scientists want in on humanity's next big space station
by Elizabeth Gibney - 17-18 Hundreds of German universities set to lose access to Elsevier journals
by Quirin Schiermeier - 18-18 Lost opportunities
by Phillip Phan & Dean Wong - 20-22 The labs that forge distant planets here on Earth
by Shannon Hall - 23-27 Use machine learning to find energy materials
by Phil De Luna & Jennifer Wei & Yoshua Bengio & Alán Aspuru-Guzik & Edward Sargent - 24-25 In good company
by Elie Dolgin - 25-27 Six principles for energy innovation
by Gabriel Chan & Anna P. Goldstein & Amitai Bin-Nun & Laura Diaz Anadon & Venkatesh Narayanamurti - 26-29 First among equals
by Mark Zastrow - 28-29 The doubly dextrous physics of Enrico Fermi
by Catherine Westfall - 29-30 How Viennese scientists fought the dogma, propaganda and prejudice of the 1930s
by Jordi Cat - 30-32 Corporates make reluctant partners
by Ichiko Fuyuno - 31-31 Scrap very useless qualifiers in research papers
by Stephen K. Donovan - 31-31 Save Iran’s cheetah from extinction
by Jamshid Parchizadeh & Samual T. Williams - 31-31 Gauging the risk from US nuclear waste
by Rodney C. Ewing - 31-31 Celebrate results of German excellence initiative
by Inna Sokolova - 32-32 Frank Brown (1943-2017)
by Bernard Wood - 34-35 DNA self-assembly scaled up
by Fei Zhang & Hao Yan - 35-37 A tip of the hat to evolutionary change
by Charles R. Marshall - 37-38 A steamy proposal for Martian clays
by Laura Schaefer - 38-39 Vivid views of the PINK1 protein
by Salima Daou & Frank Sicheri - 40-41 Two-dimensional tellurium
by Evan J. Reed - 41-42 The dark side of PD-1 receptor inhibition
by Aya Ludin & Leonard I. Zon - 41-43 India’s commitment to science begins to pay off
by T. V. Padma - 42-43 Quantum-teleportation experiments turn 20
by Nicolas Gisin - 45-47 Carbon belts and chains aid nanotech resurgence
by Tim Hornyak - 45-50 Greater future global warming inferred from Earth’s recent energy budget
by Patrick T. Brown & Ken Caldeira - 51-56 Structure of PINK1 in complex with its substrate ubiquitin
by Alexander F. Schubert & Christina Gladkova & Els Pardon & Jane L. Wagstaff & Stefan M. V. Freund & Jan Steyaert & Sarah L. Maslen & David Komander - 57-62 A transfer-RNA-derived small RNA regulates ribosome biogenesis
by Hak Kyun Kim & Gabriele Fuchs & Shengchun Wang & Wei Wei & Yue Zhang & Hyesuk Park & Biswajoy Roy-Chaudhuri & Pan Li & Jianpeng Xu & Kirk Chu & Feijie Zhang & Mei-Sze Chua & Samuel So & Qiangfeng Cliff Zhang & Peter Sarnow & Mark A. Kay - 67-71 Fractal assembly of micrometre-scale DNA origami arrays with arbitrary patterns
by Grigory Tikhomirov & Philip Petersen & Lulu Qian - 72-77 Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components
by Luvena L. Ong & Nikita Hanikel & Omar K. Yaghi & Casey Grun & Maximilian T. Strauss & Patrick Bron & Josephine Lai-Kee-Him & Florian Schueder & Bei Wang & Pengfei Wang & Jocelyn Y. Kishi & Cameron Myhrvold & Allen Zhu & Ralf Jungmann & Gaetan Bellot & Yonggang Ke & Peng Yin - 78-83 Gigadalton-scale shape-programmable DNA assemblies
by Klaus F. Wagenbauer & Christian Sigl & Hendrik Dietz - 84-87 Biotechnological mass production of DNA origami
by Florian Praetorius & Benjamin Kick & Karl L. Behler & Maximilian N. Honemann & Dirk Weuster-Botz & Hendrik Dietz - 88-91 Primordial clays on Mars formed beneath a steam or supercritical atmosphere
by Kevin M. Cannon & Stephen W. Parman & John F. Mustard - 92-95 Reconciling taxon senescence with the Red Queen’s hypothesis
by Indrė Žliobaitė & Mikael Fortelius & Nils C. Stenseth - 101-105 Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors
by Fumiji Saito & Kouyuki Hirayasu & Takeshi Satoh & Christian W. Wang & John Lusingu & Takao Arimori & Kyoko Shida & Nirianne Marie Q. Palacpac & Sawako Itagaki & Shiroh Iwanaga & Eizo Takashima & Takafumi Tsuboi & Masako Kohyama & Tadahiro Suenaga & Marco Colonna & Junichi Takagi & Thomas Lavstsen & Toshihiro Horii & Hisashi Arase - 106-109 Maternal age generates phenotypic variation in Caenorhabditis elegans
by Marcos Francisco Perez & Mirko Francesconi & Cristina Hidalgo-Carcedo & Ben Lehner - 110-115 IL-11 is a crucial determinant of cardiovascular fibrosis
by Sebastian Schafer & Sivakumar Viswanathan & Anissa A. Widjaja & Wei-Wen Lim & Aida Moreno-Moral & Daniel M. DeLaughter & Benjamin Ng & Giannino Patone & Kingsley Chow & Ester Khin & Jessie Tan & Sonia P. Chothani & Lei Ye & Owen J. L. Rackham & Nicole S. J. Ko & Norliza E. Sahib & Chee Jian Pua & Nicole T. G. Zhen & Chen Xie & Mao Wang & Henrike Maatz & Shiqi Lim & Kathrin Saar & Susanne Blachut & Enrico Petretto & Sabine Schmidt & Tracy Putoczki & Nuno Guimarães-Camboa & Hiroko Wakimoto & Sebastiaan van Heesch & Kristmundur Sigmundsson & See L. Lim & Jia L. Soon & Victor T. T. Chao & Yeow L. Chua & Teing E. Tan & Sylvia M. Evans & Yee J. Loh & Muhammad H. Jamal & Kim K. Ong & Kim C. Chua & Boon-Hean Ong & Mathew J. Chakaramakkil & Jonathan G. Seidman & Christine E. Seidman & Norbert Hubner & Kenny Y. K. Sin & Stuart A. Cook - 116-120 Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth
by Giovanni Germano & Simona Lamba & Giuseppe Rospo & Ludovic Barault & Alessandro Magrì & Federica Maione & Mariangela Russo & Giovanni Crisafulli & Alice Bartolini & Giulia Lerda & Giulia Siravegna & Benedetta Mussolin & Roberta Frapolli & Monica Montone & Federica Morano & Filippo de Braud & Nabil Amirouchene-Angelozzi & Silvia Marsoni & Maurizio D’Incalci & Armando Orlandi & Enrico Giraudo & Andrea Sartore-Bianchi & Salvatore Siena & Filippo Pietrantonio & Federica Di Nicolantonio & Alberto Bardelli - 121-125 PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis
by Tim Wartewig & Zsuzsanna Kurgyis & Selina Keppler & Konstanze Pechloff & Erik Hameister & Rupert Öllinger & Roman Maresch & Thorsten Buch & Katja Steiger & Christof Winter & Roland Rad & Jürgen Ruland - 126-131 Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
by Isaia Barbieri & Konstantinos Tzelepis & Luca Pandolfini & Junwei Shi & Gonzalo Millán-Zambrano & Samuel C. Robson & Demetrios Aspris & Valentina Migliori & Andrew J. Bannister & Namshik Han & Etienne De Braekeleer & Hannes Ponstingl & Alan Hendrick & Christopher R. Vakoc & George S. Vassiliou & Tony Kouzarides - 132-136 Genetically programmed chiral organoborane synthesis
by S. B. Jennifer Kan & Xiongyi Huang & Yosephine Gumulya & Kai Chen & Frances H. Arnold - 137-138 A test drive of a DNA-analysis toolkit in the cloud
by W. Wayt Gibbs - 139-140 A celebration of Spain’s exemplary lab leaders
by Alison Abbott - 142-142 Please consider my science-fiction story
by David G. Blake
November 2017, Volume 551, Issue 7682
- 133-133 Energy transitions
by Michelle Grayson - 134-137 Power through the ages
by Stephanie Pain - 138-140 Energize the people to effect policy change
by Craig Morris & Arne Jungjohann - 141-141 Make low-carbon energy an integral part of the knowledge economy
by Roger Fouquet - 142-144 How social scientists can help to shape climate policy
by Michael Eisenstein - 145-147 The real cost of energy
by Erica Gies - 148-149 The next step on the energy ladder
by Lucas Laursen - 150-152 The complex web behind the siting of power plants
by Peter Fairley - 181-183 Blood boosts bids to unpick membrane science
by Anna Petherick - 543-543 Pro-science budget is not enough for a Brexit world
by Venki Ramakrishnan - 549-550 AI-controlled brain implants for mood disorders tested in people
by Sara Reardon - 550-551 ‘Alien’ DNA makes proteins in living cells for the first time
by Ewen Callaway - 551-552 United Kingdom relies on science to revive flagging economy
by Elizabeth Gibney - 552-553 China to roll back regulations for traditional medicine despite safety concerns
by David Cyranoski - 554-556 Supercomputing poised for a massive speed boost
by Katherine Bourzac - 557-559 Five ways to fix statistics
by Jeff Leek & Blakeley B. McShane & Andrew Gelman & David Colquhoun & Michèle B. Nuijten & Steven N. Goodman - 561-562 How to mobilize group intelligence
by Beth Simone Noveck - 562-563 What makes teams tick
by Kara L. Hall - 563-563 Books in brief
by Barbara Kiser - 565-565 Research papers: Lifetime word limits would unleash woe
by Robert Gooding-Townsend - 565-565 Landmark contributions: Credit pioneer in plate tectonics
by William Kidd & Kevin Burke - 565-565 Clinical records: Thirty years of Dutch embryo selection
by Joep Geraedts - 565-565 Trophy hunting: Science on its own can’t dictate policy
by Chris Darimont - 566-566 Gilbert Stork (1921–2017)
by Paul A. Wender - 568-569 How chromosomes unite
by Tejas Dharmaraj & Katherine L. Wilson - 569-571 Large quantum systems tamed
by Christine Muschik - 571-572 A high-pressure situation for bacteria
by David A. Relman - 572-573 Contactless health-care sensing
by Leena Ukkonen & Lauri Sydänheimo - 573-575 Inequality has deep roots in Eurasia
by Michelle Elliott