Content
December 2016, Volume 7, Issue 1
- 1-13 MHC class II complexes sample intermediate states along the peptide exchange pathway
by Marek Wieczorek & Jana Sticht & Sebastian Stolzenberg & Sebastian Günther & Christoph Wehmeyer & Zeina El Habre & Miguel Álvaro-Benito & Frank Noé & Christian Freund - 1-13 The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis
by Gabriel J. Starrett & Elizabeth M. Luengas & Jennifer L. McCann & Diako Ebrahimi & Nuri A. Temiz & Robin P. Love & Yuqing Feng & Madison B. Adolph & Linda Chelico & Emily K. Law & Michael A. Carpenter & Reuben S Harris - 1-13 Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity
by Lauriane Galle-Treger & Yuzo Suzuki & Nisheel Patel & Ishwarya Sankaranarayanan & Jennifer L. Aron & Hadi Maazi & Lin Chen & Omid Akbari - 1-13 Two pathways regulate cortical granule translocation to prevent polyspermy in mouse oocytes
by Liam P. Cheeseman & Jérôme Boulanger & Lisa M. Bond & Melina Schuh - 1-13 Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue
by Rita Martello & Mario Leutert & Stephanie Jungmichel & Vera Bilan & Sara C. Larsen & Clifford Young & Michael O. Hottiger & Michael L. Nielsen - 1-13 Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment
by Tyler K. Ulland & Nidhi Jain & Emma E. Hornick & Eric I. Elliott & Gwendolyn M. Clay & Jeffrey J. Sadler & Kathleen A. M. Mills & Ann M. Janowski & A. Paige Davis Volk & Kai Wang & Kevin L. Legge & Lokesh Gakhar & Mohammed Bourdi & Polly J. Ferguson & Mary E. Wilson & Suzanne L. Cassel & Fayyaz S. Sutterwala - 1-13 Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication
by Kan Xing Wu & Patchara Phuektes & Pankaj Kumar & Germaine Yen Lin Goh & Dimitri Moreau & Vincent Tak Kwong Chow & Frederic Bard & Justin Jang Hann Chu - 1-13 A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis
by Ines Jeric & Gabriele Maurer & Anna Lina Cavallo & Josipa Raguz & Enrico Desideri & Bartosz Tarkowski & Matthias Parrini & Irmgard Fischer & Kurt Zatloukal & Manuela Baccarini - 1-13 Ageing and brain white matter structure in 3,513 UK Biobank participants
by Simon R. Cox & Stuart J. Ritchie & Elliot M. Tucker-Drob & David C. Liewald & Saskia P. Hagenaars & Gail Davies & Joanna M. Wardlaw & Catharine R. Gale & Mark E. Bastin & Ian J. Deary - 1-13 Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish
by Chenglu Xiao & Lu Gao & Yu Hou & Congfei Xu & Nannan Chang & Fang Wang & Keping Hu & Aibin He & Ying Luo & Jun Wang & Jinrong Peng & Fuchou Tang & Xiaojun Zhu & Jing-Wei Xiong - 1-13 A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication
by Daniela Carnevale & Marialuisa Perrotta & Fabio Pallante & Valentina Fardella & Roberta Iacobucci & Stefania Fardella & Lorenzo Carnevale & Raimondo Carnevale & Massimiliano De Lucia & Giuseppe Cifelli & Giuseppe Lembo - 1-13 Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy
by Kristin L. Griffiths & Mushtaq Ahmed & Shibali Das & Radha Gopal & William Horne & Terry D. Connell & Kelly D. Moynihan & Jay K. Kolls & Darrell J. Irvine & Maxim N. Artyomov & Javier Rangel-Moreno & Shabaana A. Khader - 1-13 Structural basis of myelin-associated glycoprotein adhesion and signalling
by Matti F. Pronker & Suzanne Lemstra & Joost Snijder & Albert J. R. Heck & Dominique M. E. Thies-Weesie & R. Jeroen Pasterkamp & Bert J. C. Janssen - 1-13 Coding and decoding libraries of sequence-defined functional copolymers synthesized via photoligation
by Nicolas Zydziak & Waldemar Konrad & Florian Feist & Sergii Afonin & Steffen Weidner & Christopher Barner-Kowollik - 1-13 Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers
by Anup Arumughan & Yvette Roske & Carolin Barth & Laura Lleras Forero & Kenny Bravo-Rodriguez & Alexandra Redel & Simona Kostova & Erik McShane & Robert Opitz & Katja Faelber & Kirstin Rau & Thorsten Mielke & Oliver Daumke & Matthias Selbach & Elsa Sanchez-Garcia & Oliver Rocks & Daniela Panáková & Udo Heinemann & Erich E. Wanker - 1-13 Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia
by Satoru Koyanagi & Naoki Kusunose & Marie Taniguchi & Takahiro Akamine & Yuki Kanado & Yui Ozono & Takahiro Masuda & Yuta Kohro & Naoya Matsunaga & Makoto Tsuda & Michael W. Salter & Kazuhide Inoue & Shigehiro Ohdo - 1-13 Microtubule organization is determined by the shape of epithelial cells
by Juan Manuel Gomez & Lyubov Chumakova & Natalia A. Bulgakova & Nicholas H. Brown - 1-13 Adaptive microwave impedance memory effect in a ferromagnetic insulator
by Hanju Lee & Barry Friedman & Kiejin Lee - 1-13 ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A
by Chris T. Williamson & Rowan Miller & Helen N. Pemberton & Samuel E. Jones & James Campbell & Asha Konde & Nicholas Badham & Rumana Rafiq & Rachel Brough & Aditi Gulati & Colm J. Ryan & Jeff Francis & Peter B. Vermulen & Andrew R. Reynolds & Philip M. Reaper & John R. Pollard & Alan Ashworth & Christopher J. Lord - 1-13 Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
by Henning Kempf & Ruth Olmer & Alexandra Haase & Annika Franke & Emiliano Bolesani & Kristin Schwanke & Diana Robles-Diaz & Michelle Coffee & Gudrun Göhring & Gerald Dräger & Oliver Pötz & Thomas Joos & Erik Martinez-Hackert & Axel Haverich & Falk F. R. Buettner & Ulrich Martin & Robert Zweigerdt - 1-13 LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells
by Pingping Zhu & Yanying Wang & Jiayi Wu & Guanling Huang & Benyu Liu & Buqing Ye & Ying Du & Guangxia Gao & Yong Tian & Lei He & Zusen Fan - 1-13 3D visualization of additive occlusion and tunable full-spectrum fluorescence in calcite
by David C. Green & Johannes Ihli & Paul D. Thornton & Mark A. Holden & Bartosz Marzec & Yi-Yeoun Kim & Alex N. Kulak & Mark A. Levenstein & Chiu Tang & Christophe Lynch & Stephen E. D. Webb & Christopher J. Tynan & Fiona C. Meldrum - 1-13 Making brain–machine interfaces robust to future neural variability
by David Sussillo & Sergey D. Stavisky & Jonathan C. Kao & Stephen I. Ryu & Krishna V. Shenoy - 1-13 Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction
by Marie A. Hanebuth & Roman Kityk & Sandra J. Fries & Alok Jain & Allison Kriel & Veronique Albanese & Tancred Frickey & Christine Peter & Matthias P. Mayer & Judith Frydman & Elke Deuerling - 1-13 Functional implications of orientation maps in primary visual cortex
by Erin Koch & Jianzhong Jin & Jose M. Alonso & Qasim Zaidi - 1-13 The pseudokinase CaMKv is required for the activity-dependent maintenance of dendritic spines
by Zhuoyi Liang & Yi Zhan & Yang Shen & Catherine C. L. Wong & John R. Yates & Florian Plattner & Kwok-On Lai & Nancy Y. Ip - 1-13 ICER is requisite for Th17 differentiation
by Nobuya Yoshida & Denis Comte & Masayuki Mizui & Kotaro Otomo & Florencia Rosetti & Tanya N. Mayadas & José C. Crispín & Sean J. Bradley & Tomohiro Koga & Michihito Kono & Maria P. Karampetsou & Vasileios C. Kyttaris & Klaus Tenbrock & George C. Tsokos - 1-13 CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation
by Shangcheng Xu & Pei Wang & Huiliang Zhang & Guohua Gong & Nicolas Gutierrez Cortes & Weizhong Zhu & Yisang Yoon & Rong Tian & Wang Wang - 1-13 Rapid construction of a whole-genome transposon insertion collection for Shewanella oneidensis by Knockout Sudoku
by Michael Baym & Lev Shaket & Isao A. Anzai & Oluwakemi Adesina & Buz Barstow - 1-13 U–Pb geochronology documents out-of-sequence emplacement of ultramafic layers in the Bushveld Igneous Complex of South Africa
by James E. Mungall & Sandra L. Kamo & Stewart McQuade - 1-13 Genome-wide compendium and functional assessment of in vivo heart enhancers
by Diane E. Dickel & Iros Barozzi & Yiwen Zhu & Yoko Fukuda-Yuzawa & Marco Osterwalder & Brandon J. Mannion & Dalit May & Cailyn H. Spurrell & Ingrid Plajzer-Frick & Catherine S. Pickle & Elizabeth Lee & Tyler H. Garvin & Momoe Kato & Jennifer A. Akiyama & Veena Afzal & Ah Young Lee & David U. Gorkin & Bing Ren & Edward M. Rubin & Axel Visel & Len A. Pennacchio - 1-13 Deep phenotyping unveils hidden traits and genetic relations in subtle mutants
by Adriana San-Miguel & Peri T. Kurshan & Matthew M. Crane & Yuehui Zhao & Patrick T. McGrath & Kang Shen & Hang Lu - 1-13 Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism
by Mahya Mehrmohamadi & Lucas K. Mentch & Andrew G. Clark & Jason W. Locasale - 1-13 Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion
by Francesca Sacco & Sean J. Humphrey & Jürgen Cox & Marcel Mischnik & Anke Schulte & Thomas Klabunde & Matthias Schäfer & Matthias Mann - 1-13 Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling
by János Brunner & János Szabadics - 1-13 The Ca2+-activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons
by Go Eun Ha & Jaekwang Lee & Hankyul Kwak & Kiyeong Song & Jea Kwon & Soon-Young Jung & Joohyeon Hong & Gyeong-Eon Chang & Eun Mi Hwang & Hee-Sup Shin & C. Justin Lee & Eunji Cheong - 1-13 Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
by Jan Felix & Eaazhisai Kandiah & Steven De Munck & Yehudi Bloch & Gydo C.P. van Zundert & Kris Pauwels & Ann Dansercoer & Katka Novanska & Randy J. Read & Alexandre M.J.J. Bonvin & Bjorn Vergauwen & Kenneth Verstraete & Irina Gutsche & Savvas N. Savvides - 1-13 A bromodomain–DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT
by Thomas C. R. Miller & Bernd Simon & Vladimir Rybin & Helga Grötsch & Sandrine Curtet & Saadi Khochbin & Teresa Carlomagno & Christoph W. Müller - 1-13 Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres
by Wei-Hao Shang & Tetsuya Hori & Frederick G. Westhorpe & Kristina M. Godek & Atsushi Toyoda & Sadahiko Misu & Norikazu Monma & Kazuho Ikeo & Christopher W. Carroll & Yasunari Takami & Asao Fujiyama & Hiroshi Kimura & Aaron F. Straight & Tatsuo Fukagawa - 1-13 Replication intermediates that escape Dna2 activity are processed by Holliday junction resolvase Yen1
by Gizem Ölmezer & Maryna Levikova & Dominique Klein & Benoît Falquet & Gabriele Alessandro Fontana & Petr Cejka & Ulrich Rass - 1-13 Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala
by Kenneth M. McCullough & Dennis Choi & Jidong Guo & Kelsey Zimmerman & Jordan Walton & Donald G. Rainnie & Kerry J. Ressler - 1-13 p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis
by Robert A.H. van de Ven & Jolien S. de Groot & Danielle Park & Robert van Domselaar & Danielle de Jong & Karoly Szuhai & Elsken van der Wall & Oscar M. Rueda & H. Raza Ali & Carlos Caldas & Paul J. van Diest & Martin W. Hetzer & Erik Sahai & Patrick W.B. Derksen - 1-13 The STIM1-binding site nexus remotely controls Orai1 channel gating
by Yandong Zhou & Xiangyu Cai & Natalia A. Loktionova & Xianming Wang & Robert M. Nwokonko & Xizhuo Wang & Youjun Wang & Brad S. Rothberg & Mohamed Trebak & Donald L. Gill - 1-13 PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
by Min Xie & Yan Yu & Rui Kang & Shan Zhu & Liangchun Yang & Ling Zeng & Xiaofang Sun & Minghua Yang & Timothy R. Billiar & Haichao Wang & Lizhi Cao & Jianxin Jiang & Daolin Tang - 1-13 Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
by Carol Sheppard & Fabian Blombach & Adam Belsom & Sarah Schulz & Tina Daviter & Katherine Smollett & Emilie Mahieu & Susanne Erdmann & Philip Tinnefeld & Roger Garrett & Dina Grohmann & Juri Rappsilber & Finn Werner - 1-13 Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport
by María-Victoria Hinckelmann & Amandine Virlogeux & Christian Niehage & Christel Poujol & Daniel Choquet & Bernard Hoflack & Diana Zala & Frédéric Saudou - 1-13 Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events
by Arghavan Ashouri & Volkan I. Sayin & Jimmy Van den Eynden & Simranjit X. Singh & Thales Papagiannakopoulos & Erik Larsson - 1-13 Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
by Qian Chen & Ligeng Xu & Chao Liang & Chao Wang & Rui Peng & Zhuang Liu - 1-13 Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease
by Michael W. Beck & Jeffrey S. Derrick & Richard A. Kerr & Shin Bi Oh & Woo Jong Cho & Shin Jung C. Lee & Yonghwan Ji & Jiyeon Han & Zahra Aliakbar Tehrani & Nayoung Suh & Sujeong Kim & Scott D. Larsen & Kwang S. Kim & Joo-Yong Lee & Brandon T. Ruotolo & Mi Hee Lim - 1-13 Increased global transcription activity as a mechanism of replication stress in cancer
by Panagiotis Kotsantis & Lara Marques Silva & Sarah Irmscher & Rebecca M. Jones & Lisa Folkes & Natalia Gromak & Eva Petermann - 1-13 Tuning the role of charge-transfer states in intramolecular singlet exciton fission through side-group engineering
by Steven Lukman & Kai Chen & Justin M. Hodgkiss & David H. P. Turban & Nicholas D. M. Hine & Shaoqiang Dong & Jishan Wu & Neil C. Greenham & Andrew J. Musser - 1-13 Coupled ATPase-adenylate kinase activity in ABC transporters
by Hundeep Kaur & Andrea Lakatos-Karoly & Ramona Vogel & Anne Nöll & Robert Tampé & Clemens Glaubitz - 1-13 The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
by Anke Harsman & Silke Oeljeklaus & Christoph Wenger & Jonathan L. Huot & Bettina Warscheid & André Schneider - 1-13 Ventral tegmental area glutamate neurons co-release GABA and promote positive reinforcement
by Ji Hoon Yoo & Vivien Zell & Navarre Gutierrez-Reed & Johnathan Wu & Reed Ressler & Mohammad Ali Shenasa & Alexander B. Johnson & Kathryn H. Fife & Lauren Faget & Thomas S. Hnasko - 1-13 Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor
by Kavya Ramkumar & Soma Samanta & Anahita Kyani & Suhui Yang & Shuzo Tamura & Elizabeth Ziemke & Jeanne A. Stuckey & Si Li & Krishnapriya Chinnaswamy & Hiroyuki Otake & Bikash Debnath & Vladimir Yarovenko & Judith S. Sebolt-Leopold & Mats Ljungman & Nouri Neamati - 1-13 Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy
by Jundong Shao & Hanhan Xie & Hao Huang & Zhibin Li & Zhengbo Sun & Yanhua Xu & Quanlan Xiao & Xue-Feng Yu & Yuetao Zhao & Han Zhang & Huaiyu Wang & Paul K. Chu - 1-13 Akkermansia muciniphila mediates negative effects of IFNγ on glucose metabolism
by Renee L. Greer & Xiaoxi Dong & Ana Carolina F. Moraes & Ryszard A. Zielke & Gabriel R. Fernandes & Ekaterina Peremyslova & Stephany Vasquez-Perez & Alexi A. Schoenborn & Everton P. Gomes & Alexandre C. Pereira & Sandra R. G. Ferreira & Michael Yao & Ivan J. Fuss & Warren Strober & Aleksandra E. Sikora & Gregory A. Taylor & Ajay S. Gulati & Andrey Morgun & Natalia Shulzhenko - 1-13 Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis
by Isabel Ohs & Maries van den Broek & Kathrin Nussbaum & Christian Münz & Sebastian J. Arnold & Sergio A. Quezada & Sonia Tugues & Burkhard Becher - 1-13 Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone
by Bin Huang & Wenhao Wang & Qingchu Li & Zhenyu Wang & Bo Yan & Zhongmin Zhang & Liang Wang & Minjun Huang & Chunhong Jia & Jiansen Lu & Sichi Liu & Hongdong Chen & Mangmang Li & Daozhang Cai & Yu Jiang & Dadi Jin & Xiaochun Bai - 1-13 A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi
by Corinne Stoetzel & Séverine Bär & Johan-Owen De Craene & Sophie Scheidecker & Christelle Etard & Johana Chicher & Jennifer R. Reck & Isabelle Perrault & Véronique Geoffroy & Kirsley Chennen & Uwe Strähle & Philippe Hammann & Sylvie Friant & Hélène Dollfus - 1-13 Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
by Stephen L. Pinkosky & Roger S. Newton & Emily A. Day & Rebecca J. Ford & Sarka Lhotak & Richard C. Austin & Carolyn M. Birch & Brennan K. Smith & Sergey Filippov & Pieter H.E. Groot & Gregory R. Steinberg & Narendra D. Lalwani - 1-13 Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
by Marta Jelitai & Paolo Puggioni & Taro Ishikawa & Arianna Rinaldi & Ian Duguid - 1-13 Large-scale self-organization of reconfigurable topological defect networks in nematic liquid crystals
by Yuji Sasaki & V.S.R. Jampani & Chiharu Tanaka & Nobutaka Sakurai & Shin Sakane & Khoa V. Le & Fumito Araoka & Hiroshi Orihara - 1-13 Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging
by J. K. Hefendehl & J. LeDue & R. W. Y. Ko & J. Mahler & T. H. Murphy & B. A. MacVicar - 1-13 Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury
by Mildred C. Embree & Mo Chen & Serhiy Pylawka & Danielle Kong & George M. Iwaoka & Ivo Kalajzic & Hai Yao & Chancheng Shi & Dongming Sun & Tzong-Jen Sheu & David A. Koslovsky & Alia Koch & Jeremy J. Mao - 1-13 MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated
by Michal Smida & Ferran Fece de la Cruz & Claudia Kerzendorfer & Iris Z. Uras & Barbara Mair & Abdelghani Mazouzi & Tereza Suchankova & Tomasz Konopka & Amanda M. Katz & Keren Paz & Katalin Nagy-Bojarszky & Markus K. Muellner & Zsuzsanna Bago-Horvath & Eric B. Haura & Joanna I. Loizou & Sebastian M. B. Nijman - 1-13 An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes
by Yun Sung Cho & Hyunho Kim & Hak-Min Kim & Sungwoong Jho & JeHoon Jun & Yong Joo Lee & Kyun Shik Chae & Chang Geun Kim & Sangsoo Kim & Anders Eriksson & Jeremy S. Edwards & Semin Lee & Byung Chul Kim & Andrea Manica & Tae-Kwang Oh & George M. Church & Jong Bhak - 1-13 Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
by Taylor W. Schmitz & R. Nathan Spreng - 1-13 Structural characterization of antibiotic self-immunity tRNA synthetase in plant tumour biocontrol agent
by Shaileja Chopra & Andrés Palencia & Cornelia Virus & Sarah Schulwitz & Brenda R. Temple & Stephen Cusack & John Reader - 1-13 Blood flow controls bone vascular function and osteogenesis
by Saravana K. Ramasamy & Anjali P. Kusumbe & Maria Schiller & Dagmar Zeuschner & M. Gabriele Bixel & Carlo Milia & Jaba Gamrekelashvili & Anne Limbourg & Alexander Medvinsky & Massimo M. Santoro & Florian P. Limbourg & Ralf H. Adams - 1-13 HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
by Petter Holland & Helene Knævelsrud & Kristiane Søreng & Benan J. Mathai & Alf Håkon Lystad & Serhiy Pankiv & Gunnveig T. Bjørndal & Sebastian W. Schultz & Viola H. Lobert & Robin B. Chan & Bowen Zhou & Knut Liestøl & Sven R. Carlsson & Thomas J. Melia & Gilbert Di Paolo & Anne Simonsen - 1-13 Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases
by Dominique Padovani & Assia Hessani & Francine T. Castillo & Géraldine Liot & Mireille Andriamihaja & Annaïg Lan & Camilla Pilati & François Blachier & Suvajit Sen & Erwan Galardon & Isabelle Artaud - 1-13 Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-κB and osteosarcoma progression
by Swathi V. Iyer & Atul Ranjan & Harold K. Elias & Alejandro Parrales & Hiromi Sasaki & Badal C. Roy & Shahid Umar & Ossama W. Tawfik & Tomoo Iwakuma - 1-13 Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation
by Young A. Yoo & Meejeon Roh & Anum F. Naseem & Barbara Lysy & Mohamed M. Desouki & Kenji Unno & Sarki A. Abdulkadir - 1-13 Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny
by Felicity M. Davis & Bethan Lloyd-Lewis & Olivia B. Harris & Sarah Kozar & Douglas J. Winton & Leila Muresan & Christine J. Watson - 1-14 Altered intestinal microbiota–host mitochondria crosstalk in new onset Crohn’s disease
by Walid Mottawea & Cheng-Kang Chiang & Marcus Mühlbauer & Amanda E. Starr & James Butcher & Turki Abujamel & Shelley A. Deeke & Annette Brandel & Hu Zhou & Shadi Shokralla & Mehrdad Hajibabaei & Ruth Singleton & Eric I. Benchimol & Christian Jobin & David R. Mack & Daniel Figeys & Alain Stintzi - 1-14 Shifting transcriptional machinery is required for long-term memory maintenance and modification in Drosophila mushroom bodies
by Yukinori Hirano & Kunio Ihara & Tomoko Masuda & Takuya Yamamoto & Ikuko Iwata & Aya Takahashi & Hiroko Awata & Naosuke Nakamura & Mai Takakura & Yusuke Suzuki & Junjiro Horiuchi & Hiroyuki Okuno & Minoru Saitoe - 1-14 Anthropogenic impacts on mosquito populations in North America over the past century
by Ilia Rochlin & Ary Faraji & Dominick V. Ninivaggi & Christopher M. Barker & A. Marm Kilpatrick - 1-14 In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075
by Xia Wu & Juan D. Chavez & Devin K. Schweppe & Chunxiang Zheng & Chad R. Weisbrod & Jimmy K. Eng & Ananya Murali & Samuel A. Lee & Elizabeth Ramage & Larry A. Gallagher & Hemantha D. Kulasekara & Mauna E. Edrozo & Cassandra N. Kamischke & Mitchell J. Brittnacher & Samuel I. Miller & Pradeep K. Singh & Colin Manoil & James E. Bruce - 1-14 Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers
by Roni Allaoui & Caroline Bergenfelz & Sofie Mohlin & Catharina Hagerling & Kiarash Salari & Zena Werb & Robin L. Anderson & Stephen P. Ethier & Karin Jirström & Sven Påhlman & Daniel Bexell & Balázs Tahin & Martin E. Johansson & Christer Larsson & Karin Leandersson - 1-14 Transduction of group I mGluR-mediated synaptic plasticity by β-arrestin2 signalling
by Andrew G. Eng & Daniel A. Kelver & Tristan P. Hedrick & Geoffrey T. Swanson - 1-14 The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation
by Kwok Ho Yip & Natasha Kolesnikoff & Nicholas Hauschild & Lisa Biggs & Angel F. Lopez & Stephen J. Galli & Sharad Kumar & Michele A. Grimbaldeston - 1-14 Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10
by Lars Ellenrieder & Łukasz Opaliński & Lars Becker & Vivien Krüger & Oliver Mirus & Sebastian P. Straub & Katharina Ebell & Nadine Flinner & Sebastian B. Stiller & Bernard Guiard & Chris Meisinger & Nils Wiedemann & Enrico Schleiff & Richard Wagner & Nikolaus Pfanner & Thomas Becker - 1-14 Sensory feedback synchronizes motor and sensory neuronal networks in the neonatal rat spinal cord
by Ana R. Inácio & Azat Nasretdinov & Julia Lebedeva & Roustem Khazipov - 1-14 Self-motion evokes precise spike timing in the primate vestibular system
by Mohsen Jamali & Maurice J. Chacron & Kathleen E. Cullen - 1-14 Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma
by Xiao-Yan Ming & Li Fu & Li-Yi Zhang & Yan-Ru Qin & Ting-Ting Cao & Kwok Wah Chan & Stephanie Ma & Dan Xie & Xin-Yuan Guan - 1-14 Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism
by Tatsuya Tamura & Hiroshi Noda & Eri Joyashiki & Maiko Hoshino & Tomoyuki Watanabe & Masahiko Kinosaki & Yoshikazu Nishimura & Tohru Esaki & Kotaro Ogawa & Taiji Miyake & Shinichi Arai & Masaru Shimizu & Hidetomo Kitamura & Haruhiko Sato & Yoshiki Kawabe - 1-14 Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding
by Sophia Ungelenk & Fatemeh Moayed & Chi-Ting Ho & Tomas Grousl & Annette Scharf & Alireza Mashaghi & Sander Tans & Matthias P. Mayer & Axel Mogk & Bernd Bukau - 1-14 An elastic element in the protocadherin-15 tip link of the inner ear
by Raul Araya-Secchi & Brandon L. Neel & Marcos Sotomayor - 1-14 The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities
by Chu-Chiao Wu & Sunhee Lee & Srinivas Malladi & Miao-Der Chen & Nicholas J. Mastrandrea & Zhiwen Zhang & Shawn B. Bratton - 1-14 Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response
by Jan Rossaint & Katharina Kühne & Jennifer Skupski & Hugo Van Aken & Mark R. Looney & Andres Hidalgo & Alexander Zarbock - 1-14 NQO1 inhibits proteasome-mediated degradation of HIF-1α
by Eun-Taex Oh & Jung-whan Kim & Joon Mee Kim & Soo Jung Kim & Jae-Seon Lee & Soon-Sun Hong & Justin Goodwin & Robin J. Ruthenborg & Myung Gu Jung & Hae-June Lee & Chul-Ho Lee & Eun Sung Park & Chulhee Kim & Heon Joo Park - 1-14 Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
by Alexander Belyy & Dorothée Raoux-Barbot & Cosmin Saveanu & Abdelkader Namane & Vasily Ogryzko & Lina Worpenberg & Violaine David & Veronique Henriot & Souad Fellous & Christien Merrifield & Elodie Assayag & Daniel Ladant & Louis Renault & Undine Mechold - 1-14 Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge
by Pascal Blanc & Ludovic Moro-Sibilot & Lucas Barthly & Ferdinand Jagot & Sébastien This & Simon de Bernard & Laurent Buffat & Sébastien Dussurgey & Renaud Colisson & Elias Hobeika & Thierry Fest & Morgan Taillardet & Olivier Thaunat & Antoine Sicard & Paul Mondière & Laurent Genestier & Stephen L. Nutt & Thierry Defrance - 1-14 Arabidopsis seed germination speed is controlled by SNL histone deacetylase-binding factor-mediated regulation of AUX1
by Zhi Wang & Fengying Chen & Xiaoying Li & Hong Cao & Meng Ding & Cun Zhang & Jinghong Zuo & Chaonan Xu & Jimei Xu & Xin Deng & Yong Xiang & Wim J. J. Soppe & Yongxiu Liu - 1-14 Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
by Thierry Jardé & Bethan Lloyd-Lewis & Mairian Thomas & Howard Kendrick & Lorenzo Melchor & Lauriane Bougaret & Peter D. Watson & Kenneth Ewan & Matthew J. Smalley & Trevor C. Dale - 1-14 Decrease of SYNGAP1 in GABAergic cells impairs inhibitory synapse connectivity, synaptic inhibition and cognitive function
by Martin H. Berryer & Bidisha Chattopadhyaya & Paul Xing & Ilse Riebe & Ciprian Bosoi & Nathalie Sanon & Judith Antoine-Bertrand & Maxime Lévesque & Massimo Avoli & Fadi F. Hamdan & Lionel Carmant & Nathalie Lamarche-Vane & Jean-Claude Lacaille & Jacques L. Michaud & Graziella Di Cristo - 1-14 Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus
by Polona Jager & Zhiwen Ye & Xiao Yu & Laskaro Zagoraiou & Hong-Ting Prekop & Juha Partanen & Thomas M. Jessell & William Wisden & Stephen G. Brickley & Alessio Delogu - 1-14 Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
by Samuel A. J. Trammell & Mark S. Schmidt & Benjamin J. Weidemann & Philip Redpath & Frank Jaksch & Ryan W. Dellinger & Zhonggang Li & E. Dale Abel & Marie E. Migaud & Charles Brenner - 1-14 Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment
by Keisuke Katsushima & Atsushi Natsume & Fumiharu Ohka & Keiko Shinjo & Akira Hatanaka & Norihisa Ichimura & Shinya Sato & Satoru Takahashi & Hiroshi Kimura & Yasushi Totoki & Tatsuhiro Shibata & Mitsuru Naito & Hyun Jin Kim & Kanjiro Miyata & Kazunori Kataoka & Yutaka Kondo - 1-14 Tiam1/Rac1 complex controls Il17a transcription and autoimmunity
by Ahmed T. Kurdi & Ribal Bassil & Marta Olah & Chuan Wu & Sheng Xiao & Mariko Taga & Michael Frangieh & Thomas Buttrick & William Orent & Elizabeth M. Bradshaw & Samia J. Khoury & Wassim Elyaman - 1-14 EIN2-dependent regulation of acetylation of histone H3K14 and non-canonical histone H3K23 in ethylene signalling
by Fan Zhang & Bin Qi & Likai Wang & Bo Zhao & Siddharth Rode & Nathaniel D. Riggan & Joseph R. Ecker & Hong Qiao - 1-14 Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors
by Andrea M. Zuhl & Charles E. Nolan & Michael A. Brodney & Sherry Niessen & Kevin Atchison & Christopher Houle & David A. Karanian & Claude Ambroise & Jeffrey W. Brulet & Elizabeth M. Beck & Shawn D. Doran & Brian T. O’Neill & Christopher W. am Ende & Cheng Chang & Kieran F. Geoghegan & Graham M. West & Joshua C. Judkins & Xinjun Hou & David R. Riddell & Douglas S. Johnson - 1-14 Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire
by Yik Andy Yeung & Davide Foletti & Xiaodi Deng & Yasmina Abdiche & Pavel Strop & Jacob Glanville & Steven Pitts & Kevin Lindquist & Purnima D. Sundar & Marina Sirota & Adela Hasa-Moreno & Amber Pham & Jody Melton Witt & Irene Ni & Jaume Pons & David Shelton & Arvind Rajpal & Javier Chaparro-Riggers - 1-14 Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer
by Yundong He & Shihong Peng & Jinhua Wang & Huang Chen & Xiaonan Cong & Ang Chen & Meichun Hu & Min Qin & Haigang Wu & Shuman Gao & Liguo Wang & Xin Wang & Zhengfang Yi & Mingyao Liu - 1-14 The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
by Feng Zhang & Claudia Prahst & Thomas Mathivet & Laurence Pibouin-Fragner & Jiasheng Zhang & Gael Genet & Raymond Tong & Alexandre Dubrac & Anne Eichmann - 1-14 CUG-binding protein 1 regulates HSC activation and liver fibrogenesis
by Xingxin Wu & Xudong Wu & Yuxiang Ma & Fenli Shao & Yang Tan & Tao Tan & Liyun Gu & Yang Zhou & Beicheng Sun & Yang Sun & Xuefeng Wu & Qiang Xu - 1-14 Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation
by Martijn H. den Brok & Christian Büll & Melissa Wassink & Annemarie M. de Graaf & Jori A. Wagenaars & Marthe Minderman & Mayank Thakur & Sebastian Amigorena & Eric O. Rijke & Carla C. Schrier & Gosse J. Adema - 1-14 Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
by Swaminathan Venkatesh & Hua Li & Madelaine M. Gogol & Jerry L. Workman - 1-14 SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores
by Teng Li & Liang Chen & Juanxian Cheng & Jiang Dai & Yijiao Huang & Jian Zhang & Zhaoshan Liu & Ang Li & Na Li & Hongxia Wang & Xiaomin Yin & Kun He & Ming Yu & Tao Zhou & Xuemin Zhang & Qing Xia - 1-14 A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice
by Deepak Tripathi & Sambasivan Venkatasubramanian & Satyanarayana S. Cheekatla & Padmaja Paidipally & Elwyn Welch & Amy R. Tvinnereim & Ramakrishna Vankayalapati - 1-14 17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
by Benjamin Joachim Schmiedel & Grégory Seumois & Daniela Samaniego-Castruita & Justin Cayford & Veronique Schulten & Lukas Chavez & Ferhat Ay & Alessandro Sette & Bjoern Peters & Pandurangan Vijayanand - 1-14 Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies
by Miriam Colombo & Luisa Fiandra & Giulia Alessio & Serena Mazzucchelli & Manuela Nebuloni & Clara De Palma & Karsten Kantner & Beatriz Pelaz & Rany Rotem & Fabio Corsi & Wolfgang J. Parak & Davide Prosperi - 1-14 Local synthesis of dynein cofactors matches retrograde transport to acutely changing demands
by Joseph M. Villarin & Ethan P. McCurdy & José C. Martínez & Ulrich Hengst - 1-14 Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis
by Satish Khurana & Sarah Schouteden & Javed K. Manesia & Albert Santamaria-Martínez & Joerg Huelsken & Adam Lacy-Hulbert & Catherine M. Verfaillie - 1-14 Hyperglycaemia inhibits REG3A expression to exacerbate TLR3-mediated skin inflammation in diabetes
by Yelin Wu & Yanchun Quan & Yuanqi Liu & Keiwei Liu & Hongquan Li & Ziwei Jiang & Tian Zhang & Hu Lei & Katherine A. Radek & Dongqing Li & Zhenhua Wang & Jilong Lu & Wang Wang & Shizhao Ji & Zhaofan Xia & Yuping Lai - 1-14 BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity
by Rikke D. Rasmussen & Madhavsai K. Gajjar & Lucie Tuckova & Kamilla E. Jensen & Apolinar Maya-Mendoza & Camilla B. Holst & Kjeld Møllgaard & Jane S. Rasmussen & Jannick Brennum & Jiri Bartek & Martin Syrucek & Eva Sedlakova & Klaus K. Andersen & Marie H. Frederiksen & Jiri Bartek & Petra Hamerlik - 1-14 Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche
by Xingbin Hu & Mayra Garcia & Lihong Weng & Xiaoman Jung & Jodi L. Murakami & Bijender Kumar & Charles D. Warden & Ivan Todorov & Ching-Cheng Chen - 1-14 Hepcidin inhibits Smad3 phosphorylation in hepatic stellate cells by impeding ferroportin-mediated regulation of Akt
by Chang Yeob Han & Ja Hyun Koo & Sung Hoon Kim & Sara Gardenghi & Stefano Rivella & Pavel Strnad & Se Jin Hwang & Sang Geon Kim - 1-14 Histone variant H3F3A promotes lung cancer cell migration through intronic regulation
by Seong-Min Park & Eun-Young Choi & Mingyun Bae & Sunshin Kim & Jong Bae Park & Heon Yoo & Jung Kyoon Choi & Youn-Jae Kim & Seung-Hoon Lee & In-Hoo Kim - 1-14 Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets
by Hristo Georgiev & Inga Ravens & Charaf Benarafa & Reinhold Förster & Günter Bernhardt - 1-14 Vasculogenic mimicry in small cell lung cancer
by Stuart C. Williamson & Robert L. Metcalf & Francesca Trapani & Sumitra Mohan & Jenny Antonello & Benjamin Abbott & Hui Sun Leong & Christopher P. E. Chester & Nicole Simms & Radoslaw Polanski & Daisuke Nonaka & Lynsey Priest & Alberto Fusi & Fredrika Carlsson & Anders Carlsson & Mary J. C. Hendrix & Richard E. B. Seftor & Elisabeth A. Seftor & Dominic G. Rothwell & Andrew Hughes & James Hicks & Crispin Miller & Peter Kuhn & Ged Brady & Kathryn L. Simpson & Fiona H. Blackhall & Caroline Dive - 1-14 Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
by N. T. Ventham & N. A. Kennedy & A. T. Adams & R. Kalla & S. Heath & K. R. O'Leary & H. Drummond & D. C. Wilson & I. G. Gut & E. R. Nimmo & J. Satsangi - 1-14 SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
by Nkerorema Djodji Damas & Michela Marcatti & Christophe Côme & Lise Lotte Christensen & Morten Muhlig Nielsen & Roland Baumgartner & Helene Maria Gylling & Giulia Maglieri & Carsten Friis Rundsten & Stefan E. Seemann & Nicolas Rapin & Simon Thézenas & Søren Vang & Torben Ørntoft & Claus Lindbjerg Andersen & Jakob Skou Pedersen & Anders H. Lund - 1-14 Structural basis for Epstein–Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins
by Karthik Sathiyamoorthy & Yao Xiong Hu & Britta S. Möhl & Jia Chen & Richard Longnecker & Theodore S. Jardetzky - 1-14 Reprogramming the immunological microenvironment through radiation and targeting Axl
by Todd A. Aguilera & Marjan Rafat & Laura Castellini & Hussein Shehade & Mihalis S. Kariolis & Angela Bik-Yu Hui & Henning Stehr & Rie von Eyben & Dadi Jiang & Lesley G. Ellies & Albert C. Koong & Maximilian Diehn & Erinn B. Rankin & Edward E. Graves & Amato J. Giaccia - 1-14 Asynchronous fate decisions by single cells collectively ensure consistent lineage composition in the mouse blastocyst
by Néstor Saiz & Kiah M. Williams & Venkatraman E. Seshan & Anna-Katerina Hadjantonakis - 1-14 In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery
by Raman Bahal & Nicole Ali McNeer & Elias Quijano & Yanfeng Liu & Parker Sulkowski & Audrey Turchick & Yi-Chien Lu & Dinesh C. Bhunia & Arunava Manna & Dale L. Greiner & Michael A. Brehm & Christopher J. Cheng & Francesc López-Giráldez & Adele Ricciardi & Jagadish Beloor & Diane S. Krause & Priti Kumar & Patrick G. Gallagher & Demetrios T. Braddock & W. Mark Saltzman & Danith H. Ly & Peter M. Glazer - 1-14 IL-12 protects from psoriasiform skin inflammation
by Paulina Kulig & Stephanie Musiol & Sandra Nicole Freiberger & Bettina Schreiner & Gabor Gyülveszi & Giancarlo Russo & Stanislav Pantelyushin & Kenji Kishihara & Francesca Alessandrini & Thomas Kündig & Federica Sallusto & Günther F.L. Hofbauer & Stefan Haak & Burkhard Becher - 1-14 Molecular and electronic structure of terminal and alkali metal-capped uranium(V) nitride complexes
by David M. King & Peter A. Cleaves & Ashley J. Wooles & Benedict M. Gardner & Nicholas F. Chilton & Floriana Tuna & William Lewis & Eric J. L. McInnes & Stephen T. Liddle - 1-14 REST regulation of gene networks in adult neural stem cells
by Shradha Mukherjee & Rebecca Brulet & Ling Zhang & Jenny Hsieh - 1-14 Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
by Martin M. Corcoran & Ganesh E. Phad & Néstor Vázquez Bernat & Christiane Stahl-Hennig & Noriyuki Sumida & Mats A.A. Persson & Marcel Martin & Gunilla B. Karlsson Hedestam - 1-14 In vivo continuous evolution of genes and pathways in yeast
by Nathan Crook & Joseph Abatemarco & Jie Sun & James M. Wagner & Alexander Schmitz & Hal S. Alper - 1-14 EGFR oligomerization organizes kinase-active dimers into competent signalling platforms
by Sarah R. Needham & Selene K. Roberts & Anton Arkhipov & Venkatesh P. Mysore & Christopher J. Tynan & Laura C. Zanetti-Domingues & Eric T. Kim & Valeria Losasso & Dimitrios Korovesis & Michael Hirsch & Daniel J. Rolfe & David T. Clarke & Martyn D. Winn & Alireza Lajevardipour & Andrew H. A. Clayton & Linda J. Pike & Michela Perani & Peter J. Parker & Yibing Shan & David E. Shaw & Marisa L. Martin-Fernandez - 1-14 Critical exponents and scaling invariance in the absence of a critical point
by N. Saratz & D. A. Zanin & U. Ramsperger & S. A. Cannas & D. Pescia & A. Vindigni - 1-15 Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death
by Teresa L. M. Thurston & Sophie A. Matthews & Elliott Jennings & Eric Alix & Feng Shao & Avinash R. Shenoy & Mark A. Birrell & David W. Holden - 1-15 Rapid tuning shifts in human auditory cortex enhance speech intelligibility
by Christopher R. Holdgraf & Wendy de Heer & Brian Pasley & Jochem Rieger & Nathan Crone & Jack J. Lin & Robert T. Knight & Frédéric E. Theunissen - 1-15 The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis
by Shuo Geng & Keqiang Chen & Ruoxi Yuan & Liang Peng & Urmila Maitra & Na Diao & Chun Chen & Yao Zhang & Yuan Hu & Chen-Feng Qi & Susan Pierce & Wenhua Ling & Huabao Xiong & Liwu Li - 1-15 Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors
by Hui Cheng & Heather Yin-Kuan Ang & Chadi A. EL Farran & Pin Li & Hai Tong Fang & Tong Ming Liu & Say Li Kong & Michael Lingzi Chin & Wei Yin Ling & Edwin Kok Hao Lim & Hu Li & Tara Huber & Kyle M. Loh & Yuin-Han Loh & Bing Lim - 1-15 Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors
by R. A. Pearson & A. Gonzalez-Cordero & E. L. West & J. R. Ribeiro & N. Aghaizu & D. Goh & R. D. Sampson & A. Georgiadis & P. V. Waldron & Y. Duran & A. Naeem & M. Kloc & E. Cristante & K. Kruczek & K. Warre-Cornish & J. C. Sowden & A. J. Smith & R. R. Ali - 1-15 Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells
by Mulki Angela & Yusuke Endo & Hikari K. Asou & Takeshi Yamamoto & Damon J. Tumes & Hirotake Tokuyama & Koutaro Yokote & Toshinori Nakayama - 1-15 Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells
by Jan R. Kraehling & John H. Chidlow & Chitra Rajagopal & Michael G. Sugiyama & Joseph W. Fowler & Monica Y. Lee & Xinbo Zhang & Cristina M. Ramírez & Eon Joo Park & Bo Tao & Keyang Chen & Leena Kuruvilla & Bruno Larriveé & Ewa Folta-Stogniew & Roxana Ola & Noemi Rotllan & Wenping Zhou & Michael W. Nagle & Joachim Herz & Kevin Jon Williams & Anne Eichmann & Warren L. Lee & Carlos Fernández-Hernando & William C. Sessa - 1-15 Reorganization between preparatory and movement population responses in motor cortex
by Gamaleldin F. Elsayed & Antonio H. Lara & Matthew T. Kaufman & Mark M. Churchland & John P. Cunningham - 1-15 The GCN5-CITED2-PKA signalling module controls hepatic glucose metabolism through a cAMP-induced substrate switch
by Mashito Sakai & Tomoko Tujimura-Hayakawa & Takashi Yagi & Hiroyuki Yano & Masaru Mitsushima & Hiroyuki Unoki-Kubota & Yasushi Kaburagi & Hiroshi Inoue & Yoshiaki Kido & Masato Kasuga & Michihiro Matsumoto - 1-15 Global and hepatocyte-specific ablation of Bmal1 induces hyperlipidaemia and enhances atherosclerosis
by Xiaoyue Pan & Christopher A. Bradfield & M. Mahmood Hussain - 1-15 Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis
by Michael G. Poulos & Pradeep Ramalingam & Michael C. Gutkin & Maria Kleppe & Michael Ginsberg & Michael J. P. Crowley & Olivier Elemento & Ross L. Levine & Shahin Rafii & Jan Kitajewski & Matthew B. Greenblatt & Jae-Hyuck Shim & Jason M. Butler - 1-15 Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
by Wenjuan Pu & Hui Zhang & Xiuzhen Huang & Xueying Tian & Lingjuan He & Yue Wang & Libo Zhang & Qiaozhen Liu & Yan Li & Yi Li & Huan Zhao & Kuo Liu & Jie Lu & Yingqun Zhou & Pengyu Huang & Yu Nie & Yan Yan & Lijian Hui & Kathy O. Lui & Bin Zhou - 1-15 A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice
by Riccardo Sibilano & Nicolas Gaudenzio & Marianne K. DeGorter & Laurent L. Reber & Joseph D. Hernandez & Philipp M. Starkl & Oliwia W. Zurek & Mindy Tsai & Sonja Zahner & Stephen B. Montgomery & Axel Roers & Mitchell Kronenberg & Mang Yu & Stephen J. Galli - 1-15 Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex
by Daniela Chmiest & Nanaocha Sharma & Natacha Zanin & Christine Viaris de Lesegno & Massiullah Shafaq-Zadah & Vonick Sibut & Florent Dingli & Philippe Hupé & Stephan Wilmes & Jacob Piehler & Damarys Loew & Ludger Johannes & Gideon Schreiber & Christophe Lamaze - 1-15 Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment
by Miho Akimoto & Riruke Maruyama & Hiroyuki Takamaru & Takahiro Ochiya & Keizo Takenaga - 1-15 ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion
by Wei-Guang Li & Ming-Gang Liu & Shining Deng & Yan-Mei Liu & Lin Shang & Jing Ding & Tsan-Ting Hsu & Qin Jiang & Ying Li & Fei Li & Michael Xi Zhu & Tian-Le Xu - 1-15 Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis
by Charis E. Teh & Najoua Lalaoui & Reema Jain & Antonia N. Policheni & Melanie Heinlein & Silvia Alvarez-Diaz & Julie M. Sheridan & Eva Rieser & Stefanie Deuser & Maurice Darding & Hui-Fern Koay & Yifang Hu & Fiona Kupresanin & Lorraine A. O’Reilly & Dale I. Godfrey & Gordon K. Smyth & Philippe Bouillet & Andreas Strasser & Henning Walczak & John Silke & Daniel H. D. Gray - 1-15 GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
by Ki-Hoon Song & Mi So Park & Tulip S. Nandu & Shrikanth Gadad & Sang-Cheol Kim & Mi-Young Kim - 1-15 Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan
by Alireza Noormohammadi & Amirabbas Khodakarami & Ricardo Gutierrez-Garcia & Hyun Ju Lee & Seda Koyuncu & Tim König & Christina Schindler & Isabel Saez & Azra Fatima & Christoph Dieterich & David Vilchez - 1-15 Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging
by Feng Tian & Wenlong Yang & Daniel A. Mordes & Jin-Yuan Wang & Johnny S. Salameh & Joanie Mok & Jeannie Chew & Aarti Sharma & Ester Leno-Duran & Satomi Suzuki-Uematsu & Naoki Suzuki & Steve S. Han & Fa-Ke Lu & Minbiao Ji & Rosanna Zhang & Yue Liu & Jack Strominger & Neil A. Shneider & Leonard Petrucelli & X. Sunney Xie & Kevin Eggan - 1-15 Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
by Gustavo Monnerat & Micaela L. Alarcón & Luiz R. Vasconcellos & Camila Hochman-Mendez & Guilherme Brasil & Rosana A. Bassani & Oscar Casis & Daniela Malan & Leonardo H. Travassos & Marisa Sepúlveda & Juan Ignacio Burgos & Martin Vila-Petroff & Fabiano F. Dutra & Marcelo T. Bozza & Claudia N. Paiva & Adriana Bastos Carvalho & Adriana Bonomo & Bernd K. Fleischmann & Antonio Carlos Campos de Carvalho & Emiliano Medei - 1-15 CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells
by Jae-Ho Cho & Hee-Ok Kim & Young-Jun Ju & Yoon-Chul Kye & Gil-Woo Lee & Sung-Woo Lee & Cheol-Heui Yun & Nunzio Bottini & Kylie Webster & Christopher C. Goodnow & Charles D. Surh & Cecile King & Jonathan Sprent - 1-15 Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome
by Wen-Chin Huang & Youjun Chen & Damon T. Page - 1-15 The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog
by Jiali Jin & Jian Liu & Cong Chen & Zhenping Liu & Cong Jiang & Hongshang Chu & Weijuan Pan & Xinbo Wang & Lingqiang Zhang & Bin Li & Cizhong Jiang & Xin Ge & Xin Xie & Ping Wang - 1-15 CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
by Arindam Chaudhury & Shebna Cheema & Joseph M. Fachini & Natee Kongchan & Guojun Lu & Lukas M. Simon & Tao Wang & Sufeng Mao & Daniel G. Rosen & Michael M. Ittmann & Susan G. Hilsenbeck & Chad A. Shaw & Joel R. Neilson - 1-15 Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences
by Volker Boehm & Jennifer V. Gerbracht & Marie-Charlotte Marx & Niels H. Gehring - 1-15 Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment
by Jin Yang & Konstantinos Savvatis & Jong Seok Kang & Peidong Fan & Hongyan Zhong & Karen Schwartz & Vivian Barry & Amanda Mikels-Vigdal & Serge Karpinski & Dmytro Kornyeyev & Joanne Adamkewicz & Xuhui Feng & Qiong Zhou & Ching Shang & Praveen Kumar & Dillon Phan & Mario Kasner & Begoña López & Javier Diez & Keith C. Wright & Roxanne L. Kovacs & Peng-Sheng Chen & Thomas Quertermous & Victoria Smith & Lina Yao & Carsten Tschöpe & Ching-Pin Chang - 1-15 Functional screening for anti-CMV biologics identifies a broadly neutralizing epitope of an essential envelope protein
by Thomas J. Gardner & Kathryn R. Stein & J. Andrew Duty & Toni M. Schwarz & Vanessa M. Noriega & Thomas Kraus & Thomas M. Moran & Domenico Tortorella - 1-15 Striatal prediction errors support dynamic control of declarative memory decisions
by Jason M. Scimeca & Perri L. Katzman & David Badre - 1-15 Coordinated integrin activation by actin-dependent force during T-cell migration
by Pontus Nordenfelt & Hunter L. Elliott & Timothy A. Springer - 1-15 mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
by Xiaolei Ding & Wilhelm Bloch & Sandra Iden & Markus A. Rüegg & Michael N. Hall & Maria Leptin & Linda Partridge & Sabine A. Eming - 1-15 Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA
by Emmanuelle Despras & Méghane Sittewelle & Caroline Pouvelle & Noémie Delrieu & Agnès M Cordonnier & Patricia L Kannouche - 1-15 Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction
by Anthony C. Cruz & Madhu Ramaswamy & Claudia Ouyang & Christopher A. Klebanoff & Prabuddha Sengupta & Tori N. Yamamoto & Françoise Meylan & Stacy K. Thomas & Nathan Richoz & Robert Eil & Susan Price & Rafael Casellas & V. Koneti Rao & Jennifer Lippincott-Schwartz & Nicholas P. Restifo & Richard M. Siegel - 1-15 Global gain modulation generates time-dependent urgency during perceptual choice in humans
by Peter R. Murphy & Evert Boonstra & Sander Nieuwenhuis - 1-15 Reader domain specificity and lysine demethylase-4 family function
by Zhangli Su & Fengbin Wang & Jin-Hee Lee & Kimberly E. Stephens & Romeo Papazyan & Ekaterina Voronina & Kimberly A. Krautkramer & Ana Raman & Jeremy J. Thorpe & Melissa D. Boersma & Vyacheslav I. Kuznetsov & Mitchell D. Miller & Sean D. Taverna & George N. Phillips & John M. Denu - 1-15 Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells
by Melissa F. Brereton & Maria Rohm & Kenju Shimomura & Christian Holland & Sharona Tornovsky-Babeay & Daniela Dadon & Michaela Iberl & Margarita V. Chibalina & Sheena Lee & Benjamin Glaser & Yuval Dor & Patrik Rorsman & Anne Clark & Frances M. Ashcroft - 1-15 IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation
by Gerjon J. Ikink & Mandy Boer & Elvira R. M. Bakker & John Hilkens - 1-15 The antifungal caspofungin increases fluoroquinolone activity against Staphylococcus aureus biofilms by inhibiting N-acetylglucosamine transferase
by Wafi Siala & Soňa Kucharíková & Annabel Braem & Jef Vleugels & Paul M Tulkens & Marie-Paule Mingeot-Leclercq & Patrick Van Dijck & Françoise Van Bambeke