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A human neurodevelopmental model for Williams syndrome

Author

Listed:
  • Thanathom Chailangkarn

    (University of California San Diego, School of Medicine, UCSD Stem Cell Program
    University of California San Diego, School of Medicine
    Center for Academic Research and Training in Anthropogeny (CARTA)
    National Center for Genetic Engineering and Biotechnology (BIOTEC), Virology and Cell Technology Laboratory)

  • Cleber A. Trujillo

    (University of California San Diego, School of Medicine, UCSD Stem Cell Program
    University of California San Diego, School of Medicine
    Center for Academic Research and Training in Anthropogeny (CARTA))

  • Beatriz C. Freitas

    (University of California San Diego, School of Medicine, UCSD Stem Cell Program
    University of California San Diego, School of Medicine
    Center for Academic Research and Training in Anthropogeny (CARTA))

  • Branka Hrvoj-Mihic

    (University of California San Diego)

  • Roberto H. Herai

    (University of California San Diego, School of Medicine, UCSD Stem Cell Program
    University of California San Diego, School of Medicine
    Center for Academic Research and Training in Anthropogeny (CARTA)
    Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná (PUCPR))

  • Diana X. Yu

    (The Salk Institute for Biological Studies, Laboratory of Genetics)

  • Timothy T. Brown

    (University of California San Diego, Multimodal Imaging Laboratory
    University of California San Diego, School of Medicine
    University of California San Diego, Center for Human Development)

  • Maria C. Marchetto

    (The Salk Institute for Biological Studies, Laboratory of Genetics)

  • Cedric Bardy

    (The Salk Institute for Biological Studies, Laboratory of Genetics
    SAHMRI Mind & Brain Theme, Laboratory for Human Neurophysiology and Genetics, Flinders University School of Medicine)

  • Lauren McHenry

    (The Salk Institute for Biological Studies, Laboratory of Genetics)

  • Lisa Stefanacci

    (University of California San Diego, School of Medicine, UCSD Stem Cell Program
    University of California San Diego, School of Medicine
    Center for Academic Research and Training in Anthropogeny (CARTA)
    University of California San Diego)

  • Anna Järvinen

    (The Salk Institute for Biological Studies, Laboratory for Cognitive Neuroscience)

  • Yvonne M. Searcy

    (The Salk Institute for Biological Studies, Laboratory for Cognitive Neuroscience)

  • Michelle DeWitt

    (The Salk Institute for Biological Studies, Laboratory for Cognitive Neuroscience)

  • Wenny Wong

    (The Salk Institute for Biological Studies, Laboratory for Cognitive Neuroscience)

  • Philip Lai

    (The Salk Institute for Biological Studies, Laboratory for Cognitive Neuroscience)

  • M. Colin Ard

    (University of California San Diego, School of Medicine)

  • Kari L. Hanson

    (University of California San Diego)

  • Sarah Romero

    (University of California San Diego, School of Medicine, UCSD Stem Cell Program
    University of California San Diego, School of Medicine
    Center for Academic Research and Training in Anthropogeny (CARTA))

  • Bob Jacobs

    (Colorado College)

  • Anders M. Dale

    (University of California San Diego, Multimodal Imaging Laboratory
    University of California San Diego, School of Medicine
    University of California San Diego)

  • Li Dai

    (University of Utah
    University of Utah, The Brain Institute)

  • Julie R. Korenberg

    (University of Utah
    University of Utah, The Brain Institute)

  • Fred H. Gage

    (The Salk Institute for Biological Studies, Laboratory of Genetics
    University of California San Diego, Kavli Institute for Brain and Mind)

  • Ursula Bellugi

    (The Salk Institute for Biological Studies, Laboratory for Cognitive Neuroscience)

  • Eric Halgren

    (University of California San Diego, Multimodal Imaging Laboratory
    University of California San Diego, School of Medicine
    University of California San Diego, Kavli Institute for Brain and Mind)

  • Katerina Semendeferi

    (University of California San Diego
    University of California San Diego, Kavli Institute for Brain and Mind
    University of California San Diego, School of Medicine, Neuroscience Graduate Program)

  • Alysson R. Muotri

    (University of California San Diego, School of Medicine, UCSD Stem Cell Program
    University of California San Diego, School of Medicine
    Center for Academic Research and Training in Anthropogeny (CARTA)
    University of California San Diego, Kavli Institute for Brain and Mind)

Abstract

A human neurodevelopmental model fills the current knowledge gap in the cellular biology of Williams syndrome and could lead to further insights into the molecular mechanism underlying the disorder and the human social brain.

Suggested Citation

  • Thanathom Chailangkarn & Cleber A. Trujillo & Beatriz C. Freitas & Branka Hrvoj-Mihic & Roberto H. Herai & Diana X. Yu & Timothy T. Brown & Maria C. Marchetto & Cedric Bardy & Lauren McHenry & Lisa St, 2016. "A human neurodevelopmental model for Williams syndrome," Nature, Nature, vol. 536(7616), pages 338-343, August.
    • Handle: RePEc:nat:nature:v:536:y:2016:i:7616:d:10.1038_nature19067
    DOI: 10.1038/nature19067
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    Cited by:

    1. Carolina Gracia-Diaz & Yijing Zhou & Qian Yang & Reza Maroofian & Paula Espana-Bonilla & Chul-Hwan Lee & Shuo Zhang & Natàlia Padilla & Raquel Fueyo & Elisa A. Waxman & Sunyimeng Lei & Garrett Otrimsk, 2023. "Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders," Nature Communications, Nature, vol. 14(1), pages 1-18, December.

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