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Content
March 2018, Volume 555, Issue 7696
- 403-405 Data management made simple
by Quirin Schiermeier - 405-405 Laboratory balancing act
by Marta Paterlini - 408-408 Data
by João Ramalho-Santos
March 2018, Volume 555, Issue 7695
- 1-1 The future of medicine
by Richard Hodson - 2-4 Infection forecasts powered by big data
by Michael Eisenstein - 5-7 Four stories of antibacterial breakthroughs
by Natasha Gilbert - 8-9 The battle to tame autoimmunity
by Katherine Bourzac - 10-11 How CRISPR is transforming drug discovery
by Andrew Scott - 12-14 The mind-reading devices that can free paralysed muscles
by Neil Savage - 15-17 Fighting the inevitability of ageing
by Liam Drew - 18-19 How baby’s first microbes could be crucial to future health
by Sarah DeWeerdt - 20-22 Cleaning up pollutants to protect future health
by Karl Gruber - 23-25 A CRISPR edit for heart disease
by Anthony King - 26-29 Bringing down the cost of cancer treatment
by Elie Dolgin - 143-143 Fund ideas, not pedigree, to find fresh insight
by Thomas Sinkjær - 149-150 US scientists plot return to the Moon’s surface
by Alexandra Witze - 150-151 EU expected to vote on pesticide ban after major scientific review
by Declan Butler - 151-152 Surprise graphene discovery could unlock secrets of superconductivity
by Elizabeth Gibney - 152-153 China tests giant air cleaner to combat smog
by David Cyranoski - 153-153 Canadian science wins billions in new budget
by Brian Owens - 154-154 Latest US weather satellite highlights forecasting challenges
by Jeff Tollefson - 156-158 Attack of the extreme floods
by Alexandra Witze - 159-161 How female fellows fared at the Royal Society
by Aileen Fyfe & Camilla Mørk Røstvik - 162-163 Ominous biosecurity trends under Putin
by Gary Ackerman - 163-164 Where Blade Runner began: 50 years of Do Androids Dream of Electric Sheep?
by Ananyo Bhattacharya - 165-165 Gender parity closer among astronomers in low-income countries
by Aswin Sekhar - 165-165 Electric fish inspire inventors across the centuries
by Egidio D’Angelo & Paolo Mazzarello - 165-165 Academics should build rapport with government’s policy analysts
by Marie Claire Brisbois & Kimberly Girling & Scott Findlay - 165-165 Too few women authors on research papers in leading journals
by Yiqin Alicia Shen & Yuichi Shoda & Ione Fine - 165-165 India and Pakistan should work together for water security
by Syed Ather Hussain & Vinod C. Nayak & Ritesh G. Menezes - 166-166 Donald Lynden-Bell (1935–2018)
by Roger Davies - 168-169 A deeper look at Jupiter
by Jonathan Fortney - 169-170 Simple moral code supports cooperation
by Charles Efferson & Ernst Fehr - 170-172 A new era of rationally designed antipsychotics
by David R. Sibley & Lei Shi - 172-173 Transistors driven by superconductors
by Yoshiharu Krockenberger & Yoshitaka Taniyasu - 173-174 Mountains of diversity
by Alexander Zizka & Alexandre Antonelli - 175-182 Meta-analysis and the science of research synthesis
by Jessica Gurevitch & Julia Koricheva & Shinichi Nakagawa & Gavin Stewart - 183-189 GaN/NbN epitaxial semiconductor/superconductor heterostructures
by Rusen Yan & Guru Khalsa & Suresh Vishwanath & Yimo Han & John Wright & Sergei Rouvimov & D. Scott Katzer & Neeraj Nepal & Brian P. Downey & David A. Muller & Huili G. Xing & David J. Meyer & Debdeep Jena - 190-196 The Beaker phenomenon and the genomic transformation of northwest Europe
by Iñigo Olalde & Selina Brace & Morten E. Allentoft & Ian Armit & Kristian Kristiansen & Thomas Booth & Nadin Rohland & Swapan Mallick & Anna Szécsényi-Nagy & Alissa Mittnik & Eveline Altena & Mark Lipson & Iosif Lazaridis & Thomas K. Harper & Nick Patterson & Nasreen Broomandkhoshbacht & Yoan Diekmann & Zuzana Faltyskova & Daniel Fernandes & Matthew Ferry & Eadaoin Harney & Peter de Knijff & Megan Michel & Jonas Oppenheimer & Kristin Stewardson & Alistair Barclay & Kurt Werner Alt & Corina Liesau & Patricia Ríos & Concepción Blasco & Jorge Vega Miguel & Roberto Menduiña García & Azucena Avilés Fernández & Eszter Bánffy & Maria Bernabò-Brea & David Billoin & Clive Bonsall & Laura Bonsall & Tim Allen & Lindsey Büster & Sophie Carver & Laura Castells Navarro & Oliver E. Craig & Gordon T. Cook & Barry Cunliffe & Anthony Denaire & Kirsten Egging Dinwiddy & Natasha Dodwell & Michal Ernée & Christopher Evans & Milan Kuchařík & Joan Francès Farré & Chris Fowler & Michiel Gazenbeek & Rafael Garrido Pena & María Haber-Uriarte & Elżbieta Haduch & Gill Hey & Nick Jowett & Timothy Knowles & Ken Massy & Saskia Pfrengle & Philippe Lefranc & Olivier Lemercier & Arnaud Lefebvre & César Heras Martínez & Virginia Galera Olmo & Ana Bastida Ramírez & Joaquín Lomba Maurandi & Tona Majó & Jacqueline I. McKinley & Kathleen McSweeney & Balázs Gusztáv Mende & Alessandra Modi & Gabriella Kulcsár & Viktória Kiss & András Czene & Róbert Patay & Anna Endrődi & Kitti Köhler & Tamás Hajdu & Tamás Szeniczey & János Dani & Zsolt Bernert & Maya Hoole & Olivia Cheronet & Denise Keating & Petr Velemínský & Miroslav Dobeš & Francesca Candilio & Fraser Brown & Raúl Flores Fernández & Ana-Mercedes Herrero-Corral & Sebastiano Tusa & Emiliano Carnieri & Luigi Lentini & Antonella Valenti & Alessandro Zanini & Clive Waddington & Germán Delibes & Elisa Guerra-Doce & Benjamin Neil & Marcus Brittain & Mike Luke & Richard Mortimer & Jocelyne Desideri & Marie Besse & Günter Brücken & Mirosław Furmanek & Agata Hałuszko & Maksym Mackiewicz & Artur Rapiński & Stephany Leach & Ignacio Soriano & Katina T. Lillios & João Luís Cardoso & Michael Parker Pearson & Piotr Włodarczak & T. Douglas Price & Pilar Prieto & Pierre-Jérôme Rey & Roberto Risch & Manuel A. Rojo Guerra & Aurore Schmitt & Joël Serralongue & Ana Maria Silva & Václav Smrčka & Luc Vergnaud & João Zilhão & David Caramelli & Thomas Higham & Mark G. Thomas & Douglas J. Kennett & Harry Fokkens & Volker Heyd & Alison Sheridan & Karl-Göran Sjögren & Philipp W. Stockhammer & Johannes Krause & Ron Pinhasi & Wolfgang Haak & Ian Barnes & Carles Lalueza-Fox & David Reich - 197-203 The genomic history of southeastern Europe
by Iain Mathieson & Songül Alpaslan-Roodenberg & Cosimo Posth & Anna Szécsényi-Nagy & Nadin Rohland & Swapan Mallick & Iñigo Olalde & Nasreen Broomandkhoshbacht & Francesca Candilio & Olivia Cheronet & Daniel Fernandes & Matthew Ferry & Beatriz Gamarra & Gloria González Fortes & Wolfgang Haak & Eadaoin Harney & Eppie Jones & Denise Keating & Ben Krause-Kyora & Isil Kucukkalipci & Megan Michel & Alissa Mittnik & Kathrin Nägele & Mario Novak & Jonas Oppenheimer & Nick Patterson & Saskia Pfrengle & Kendra Sirak & Kristin Stewardson & Stefania Vai & Stefan Alexandrov & Kurt W. Alt & Radian Andreescu & Dragana Antonović & Abigail Ash & Nadezhda Atanassova & Krum Bacvarov & Mende Balázs Gusztáv & Hervé Bocherens & Michael Bolus & Adina Boroneanţ & Yavor Boyadzhiev & Alicja Budnik & Josip Burmaz & Stefan Chohadzhiev & Nicholas J. Conard & Richard Cottiaux & Maja Čuka & Christophe Cupillard & Dorothée G. Drucker & Nedko Elenski & Michael Francken & Borislava Galabova & Georgi Ganetsovski & Bernard Gély & Tamás Hajdu & Veneta Handzhyiska & Katerina Harvati & Thomas Higham & Stanislav Iliev & Ivor Janković & Ivor Karavanić & Douglas J. Kennett & Darko Komšo & Alexandra Kozak & Damian Labuda & Martina Lari & Catalin Lazar & Maleen Leppek & Krassimir Leshtakov & Domenico Lo Vetro & Dženi Los & Ivaylo Lozanov & Maria Malina & Fabio Martini & Kath McSweeney & Harald Meller & Marko Menđušić & Pavel Mirea & Vyacheslav Moiseyev & Vanya Petrova & T. Douglas Price & Angela Simalcsik & Luca Sineo & Mario Šlaus & Vladimir Slavchev & Petar Stanev & Andrej Starović & Tamás Szeniczey & Sahra Talamo & Maria Teschler-Nicola & Corinne Thevenet & Ivan Valchev & Frédérique Valentin & Sergey Vasilyev & Fanica Veljanovska & Svetlana Venelinova & Elizaveta Veselovskaya & Bence Viola & Cristian Virag & Joško Zaninović & Steve Zäuner & Philipp W. Stockhammer & Giulio Catalano & Raiko Krauß & David Caramelli & Gunita Zariņa & Bisserka Gaydarska & Malcolm Lillie & Alexey G. Nikitin & Inna Potekhina & Anastasia Papathanasiou & Dušan Borić & Clive Bonsall & Johannes Krause & Ron Pinhasi & David Reich - 204-209 Hierarchical neural architecture underlying thirst regulation
by Vineet Augustine & Sertan Kutal Gokce & Sangjun Lee & Bo Wang & Thomas J. Davidson & Frank Reimann & Fiona Gribble & Karl Deisseroth & Carlos Lois & Yuki Oka - 210-215 Environment dominates over host genetics in shaping human gut microbiota
by Daphna Rothschild & Omer Weissbrod & Elad Barkan & Alexander Kurilshikov & Tal Korem & David Zeevi & Paul I. Costea & Anastasia Godneva & Iris N. Kalka & Noam Bar & Smadar Shilo & Dar Lador & Arnau Vich Vila & Niv Zmora & Meirav Pevsner-Fischer & David Israeli & Noa Kosower & Gal Malka & Bat Chen Wolf & Tali Avnit-Sagi & Maya Lotan-Pompan & Adina Weinberger & Zamir Halpern & Shai Carmi & Jingyuan Fu & Cisca Wijmenga & Alexandra Zhernakova & Eran Elinav & Eran Segal - 216-219 Clusters of cyclones encircling Jupiter’s poles
by A. Adriani & A. Mura & G. Orton & C. Hansen & F. Altieri & M. L. Moriconi & J. Rogers & G. Eichstädt & T. Momary & A. P. Ingersoll & G. Filacchione & G. Sindoni & F. Tabataba-Vakili & B. M. Dinelli & F. Fabiano & S. J. Bolton & J. E. P. Connerney & S. K. Atreya & J. I. Lunine & F. Tosi & A. Migliorini & D. Grassi & G. Piccioni & R. Noschese & A. Cicchetti & C. Plainaki & A. Olivieri & M. E. O’Neill & D. Turrini & S. Stefani & R. Sordini & M. Amoroso - 220-222 Measurement of Jupiter’s asymmetric gravity field
by L. Iess & W. M. Folkner & D. Durante & M. Parisi & Y. Kaspi & E. Galanti & T. Guillot & W. B. Hubbard & D. J. Stevenson & J. D. Anderson & D. R. Buccino & L. Gomez Casajus & A. Milani & R. Park & P. Racioppa & D. Serra & P. Tortora & M. Zannoni & H. Cao & R. Helled & J. I. Lunine & Y. Miguel & B. Militzer & S. Wahl & J. E. P. Connerney & S. M. Levin & S. J. Bolton - 223-226 Jupiter’s atmospheric jet streams extend thousands of kilometres deep
by Y. Kaspi & E. Galanti & W. B. Hubbard & D. J. Stevenson & S. J. Bolton & L. Iess & T. Guillot & J. Bloxham & J. E. P. Connerney & H. Cao & D. Durante & W. M. Folkner & R. Helled & A. P. Ingersoll & S. M. Levin & J. I. Lunine & Y. Miguel & B. Militzer & M. Parisi & S. M. Wahl - 227-230 A suppression of differential rotation in Jupiter’s deep interior
by T. Guillot & Y. Miguel & B. Militzer & W. B. Hubbard & Y. Kaspi & E. Galanti & H. Cao & R. Helled & S. M. Wahl & L. Iess & W. M. Folkner & D. J. Stevenson & J. I. Lunine & D. R. Reese & A. Biekman & M. Parisi & D. Durante & J. E. P. Connerney & S. M. Levin & S. J. Bolton - 231-236 Monolayer atomic crystal molecular superlattices
by Chen Wang & Qiyuan He & Udayabagya Halim & Yuanyue Liu & Enbo Zhu & Zhaoyang Lin & Hai Xiao & Xidong Duan & Ziying Feng & Rui Cheng & Nathan O. Weiss & Guojun Ye & Yun-Chiao Huang & Hao Wu & Hung-Chieh Cheng & Imran Shakir & Lei Liao & Xianhui Chen & William A. Goddard III & Yu Huang & Xiangfeng Duan - 237-241 CaSiO3 perovskite in diamond indicates the recycling of oceanic crust into the lower mantle
by F. Nestola & N. Korolev & M. Kopylova & N. Rotiroti & D. G. Pearson & M. G. Pamato & M. Alvaro & L. Peruzzo & J. J. Gurney & A. E. Moore & J. Davidson - 242-245 Social norm complexity and past reputations in the evolution of cooperation
by Fernando P. Santos & Francisco C. Santos & Jorge M. Pacheco - 246-250 Global elevational diversity and diversification of birds
by Ignacio Quintero & Walter Jetz - 251-255 Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor
by William J. Zacharias & David B. Frank & Jarod A. Zepp & Michael P. Morley & Farrah A. Alkhaleel & Jun Kong & Su Zhou & Edward Cantu & Edward E. Morrisey - 256-259 The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency
by Alessandro Bertero & Stephanie Brown & Pedro Madrigal & Anna Osnato & Daniel Ortmann & Loukia Yiangou & Juned Kadiwala & Nina C. Hubner & Igor Ruiz de los Mozos & Christoph Sadée & An-Sofie Lenaerts & Shota Nakanoh & Rodrigo Grandy & Edward Farnell & Jernej Ule & Hendrik G. Stunnenberg & Sasha Mendjan & Ludovic Vallier - 260-264 Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis
by Kazumichi M. Nishida & Kazuhiro Sakakibara & Yuka W. Iwasaki & Hiromi Yamada & Ryo Murakami & Yukiko Murota & Takeshi Kawamura & Tatsuhiko Kodama & Haruhiko Siomi & Mikiko C. Siomi - 265-268 The mechanism of eukaryotic CMG helicase activation
by Max E. Douglas & Ferdos Abid Ali & Alessandro Costa & John F. X. Diffley - 269-273 Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone
by Sheng Wang & Tao Che & Anat Levit & Brian K. Shoichet & Daniel Wacker & Bryan L. Roth - 274-274 Correction: Corrigendum: Landscape of X chromosome inactivation across human tissues
by Taru Tukiainen & Alexandra-Chloé Villani & Angela Yen & Manuel A. Rivas & Jamie L. Marshall & Rahul Satija & Matt Aguirre & Laura Gauthier & Mark Fleharty & Andrew Kirby & Beryl B. Cummings & Stephane E. Castel & Konrad J. Karczewski & François Aguet & Andrea Byrnes & GTEx Consortium & Tuuli Lappalainen & Aviv Regev & Kristin G. Ardlie & Nir Hacohen & Daniel G. MacArthur - 274-274 Retraction Note: Asia’s glaciers are a regionally important buffer against drought
by Hamish D. Pritchard - 274-274 Correction: Corrigendum: Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
by Sydney M. Shaffer & Margaret C. Dunagin & Stefan R. Torborg & Eduardo A. Torre & Benjamin Emert & Clemens Krepler & Marilda Beqiri & Katrin Sproesser & Patricia A. Brafford & Min Xiao & Elliott Eggan & Ioannis N. Anastopoulos & Cesar A. Vargas-Garcia & Abhyudai Singh & Katherine L. Nathanson & Meenhard Herlyn & Arjun Raj - 275-276 Why scientists need to market themselves
by Peter Fiske - 277-277 Science PhDs lead to enjoyable jobs
by Chris Woolston - 280-280 Writing for the end of the world
by Karlo Yeager Rodríguez
March 2018, Volume 555, Issue 7694
- 7-7 Data can help to end malnutrition across Africa
by Kofi Annan - 13-14 China’s lust for jaguar fangs imperils big cats
by Barbara Fraser - 14-15 UK scientists brace for disruption from huge academic strike
by Elizabeth Gibney - 15-15 Florida residents could soon get the power to alter science classes
by Giorgia Guglielmi - 16-16 Indian scientist's sacking spotlights sexual harassment
by T. V. Padma - 17-18 Promising HIV vaccines could stall without coordinated research
by Amy Maxmen - 18-18 Researchers have finally created a tool to spot duplicated images across thousands of papers
by Declan Butler - 20-22 How flashing lights and pink noise might banish Alzheimer’s, improve memory and more
by Helen Thomson - 23-25 Six research priorities for cities and climate change
by Xuemei Bai & Richard J. Dawson & Diana Ürge-Vorsatz & Gian C. Delgado & Aliyu Salisu Barau & Shobhakar Dhakal & David Dodman & Lykke Leonardsen & Valérie Masson-Delmotte & Debra C. Roberts & Seth Schultz - 26-27 A harrowing journey through disordered sleep
by Emmanuel Mignot - 27-28 Bollywood takes on menstrual hygiene
by Subhra Priyadarshini - 29-29 Ursula K. Le Guin: an anthropologist of other worlds
by Marleen S. Barr - 30-30 Lessons from Italy’s policy shift on immunization
by Roberto Burioni & Anna Odone & Carlo Signorelli - 30-30 Call for research into a wider range of behavioural addictions
by Marc N. Potenza & Susumu Higuchi & Matthias Brand - 30-30 Smallholders need access to big-data agronomy too
by Zia Mehrabi & Daniel Jimenez & Andy Jarvis - 30-30 Risk and resilience must be independently managed
by Igor Linkov & Benjamin D. Trump & Jeffrey Keisler - 32-33 Precision maps for public health
by Brian J. Reich & Murali Haran - 33-34 Qubits break the sound barrier
by Tobias Schaetz - 34-36 A gut feeling for cellular fate
by Jackson Liang & Lucy Erin O’Brien - 36-37 Quantum upside-down cake
by Chih-Kang Shih & Allan H. MacDonald - 37-38 Tight complexes from disordered proteins
by Rebecca B. Berlow & Peter E. Wright - 38-39 A surprising chill before the cosmic dawn
by Lincoln Greenhill - 41-47 Mapping child growth failure in Africa between 2000 and 2015
by Aaron Osgood-Zimmerman & Anoushka I. Millear & Rebecca W. Stubbs & Chloe Shields & Brandon V. Pickering & Lucas Earl & Nicholas Graetz & Damaris K. Kinyoki & Sarah E. Ray & Samir Bhatt & Annie J. Browne & Roy Burstein & Ewan Cameron & Daniel C. Casey & Aniruddha Deshpande & Nancy Fullman & Peter W. Gething & Harry S. Gibson & Nathaniel J. Henry & Mario Herrero & L. Kendall Krause & Ian D. Letourneau & Aubrey J. Levine & Patrick Y. Liu & Joshua Longbottom & Benjamin K. Mayala & Jonathan F. Mosser & Abdisalan M. Noor & David M. Pigott & Ellen G. Piwoz & Puja Rao & Rahul Rawat & Robert C. Reiner & David L. Smith & Daniel J. Weiss & Kirsten E. Wiens & Ali H. Mokdad & Stephen S. Lim & Christopher J. L. Murray & Nicholas J. Kassebaum & Simon I. Hay - 48-53 Mapping local variation in educational attainment across Africa
by Nicholas Graetz & Joseph Friedman & Aaron Osgood-Zimmerman & Roy Burstein & Molly H. Biehl & Chloe Shields & Jonathan F. Mosser & Daniel C. Casey & Aniruddha Deshpande & Lucas Earl & Robert C. Reiner & Sarah E. Ray & Nancy Fullman & Aubrey J. Levine & Rebecca W. Stubbs & Benjamin K. Mayala & Joshua Longbottom & Annie J. Browne & Samir Bhatt & Daniel J. Weiss & Peter W. Gething & Ali H. Mokdad & Stephen S. Lim & Christopher J. L. Murray & Emmanuela Gakidou & Simon I. Hay - 54-60 Population snapshots predict early haematopoietic and erythroid hierarchies
by Betsabeh Khoramian Tusi & Samuel L. Wolock & Caleb Weinreb & Yung Hwang & Daniel Hidalgo & Rapolas Zilionis & Ari Waisman & Jun R. Huh & Allon M. Klein & Merav Socolovsky - 61-66 Extreme disorder in an ultrahigh-affinity protein complex
by Alessandro Borgia & Madeleine B. Borgia & Katrine Bugge & Vera M. Kissling & Pétur O. Heidarsson & Catarina B. Fernandes & Andrea Sottini & Andrea Soranno & Karin J. Buholzer & Daniel Nettels & Birthe B. Kragelund & Robert B. Best & Benjamin Schuler - 67-70 An absorption profile centred at 78 megahertz in the sky-averaged spectrum
by Judd D. Bowman & Alan E. E. Rogers & Raul A. Monsalve & Thomas J. Mozdzen & Nivedita Mahesh - 71-74 Possible interaction between baryons and dark-matter particles revealed by the first stars
by Rennan Barkana - 75-78 Fast quantum logic gates with trapped-ion qubits
by V. M. Schäfer & C. J. Ballance & K. Thirumalai & L. J. Stephenson & T. G. Ballance & A. M. Steane & D. M. Lucas - 79-82 Probing the interatomic potential of solids with strong-field nonlinear phononics
by A. von Hoegen & R. Mankowsky & M. Fechner & M. Först & A. Cavalleri - 83-88 Skin electronics from scalable fabrication of an intrinsically stretchable transistor array
by Sihong Wang & Jie Xu & Weichen Wang & Ging-Ji Nathan Wang & Reza Rastak & Francisco Molina-Lopez & Jong Won Chung & Simiao Niu & Vivian R. Feig & Jeffery Lopez & Ting Lei & Soon-Ki Kwon & Yeongin Kim & Amir M. Foudeh & Anatol Ehrlich & Andrea Gasperini & Youngjun Yun & Boris Murmann & Jeffery B.-H. Tok & Zhenan Bao - 89-93 Hadean silicate differentiation preserved by anomalous 142Nd/144Nd ratios in the Réunion hotspot source
by Bradley J. Peters & Richard W. Carlson & James M. D. Day & Mary F. Horan - 94-97 Evolutionary history resolves global organization of root functional traits
by Zeqing Ma & Dali Guo & Xingliang Xu & Mingzhen Lu & Richard D. Bardgett & David M. Eissenstat & M. Luke McCormack & Lars O. Hedin - 98-102 Circadian clock neurons constantly monitor environmental temperature to set sleep timing
by Swathi Yadlapalli & Chang Jiang & Andrew Bahle & Pramod Reddy & Edgar Meyhofer & Orie T. Shafer - 103-106 Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel
by Li He & Guangwei Si & Jiuhong Huang & Aravinthan D. T. Samuel & Norbert Perrimon - 107-111 Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells
by Yoav Lubelsky & Igor Ulitsky - 112-116 Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress
by Morgane Macheret & Thanos D. Halazonetis - 117-120 The cryo-electron microscopy structure of huntingtin
by Qiang Guo & Bin Huang & Jingdong Cheng & Manuel Seefelder & Tatjana Engler & Günter Pfeifer & Patrick Oeckl & Markus Otto & Franziska Moser & Melanie Maurer & Alexander Pautsch & Wolfgang Baumeister & Rubén Fernández-Busnadiego & Stefan Kochanek - 121-125 Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex
by Yi-Lynn Liang & Maryam Khoshouei & Alisa Glukhova & Sebastian G. B. Furness & Peishen Zhao & Lachlan Clydesdale & Cassandra Koole & Tin T. Truong & David M. Thal & Saifei Lei & Mazdak Radjainia & Radostin Danev & Wolfgang Baumeister & Ming-Wei Wang & Laurence J. Miller & Arthur Christopoulos & Patrick M. Sexton & Denise Wootten - 126-126 Correction: Corrigendum: Greater post-Neolithic wealth disparities in Eurasia than in North America and Mesoamerica
by Timothy A. Kohler & Michael E. Smith & Amy Bogaard & Gary M. Feinman & Christian E. Peterson & Alleen Betzenhauser & Matthew Pailes & Elizabeth C. Stone & Anna Marie Prentiss & Timothy J. Dennehy & Laura J. Ellyson & Linda M. Nicholas & Ronald K. Faulseit & Amy Styring & Jade Whitlam & Mattia Fochesato & Thomas A. Foor & Samuel Bowles - 126-126 Erratum: Pluripotent state transitions coordinate morphogenesis in mouse and human embryos
by Marta N. Shahbazi & Antonio Scialdone & Natalia Skorupska & Antonia Weberling & Gaelle Recher & Meng Zhu & Agnieszka Jedrusik & Liani G. Devito & Laila Noli & Iain C. Macaulay & Christa Buecker & Yakoub Khalaf & Dusko Ilic & Thierry Voet & John C. Marioni & Magdalena Zernicka-Goetz - 126-126 Correction: Corrigendum: Progress in and promise of bacterial quorum sensing research
by Marvin Whiteley & Stephen P. Diggle & E. Peter Greenberg - 127-128 The mazes with minds of their own
by Charles Choi - 129-130 How to write a first-class paper
by Virginia Gewin - 131-131 Why I won’t be silenced on climate resilience
by Virginia Gewin - 131-131 Enter our ‘scientist at work’ photo contest
by Jack Leeming - 134-134 Lava cake for the Apocalypse
by Wendy Nikel
February 2018, Volume 554, Issue 7693
- 4-5 Predicting soil carbon loss with warming
by Natasja van Gestel & Zheng Shi & Kees Jan van Groenigen & Craig W. Osenberg & Louise C. Andresen & Jeffrey S. Dukes & Mark J. Hovenden & Yiqi Luo & Anders Michelsen & Elise Pendall & Peter B. Reich & Edward A. G. Schuur & Bruce A. Hungate - 7-8 Crowther et al. reply
by T. W. Crowther & M. B. Machmuller & J. C. Carey & S. D. Allison & J. M. Blair & S. D. Bridgham & A. J. Burton & F. A. Dijkstra & B. Elberling & M. Estiarte & K. S. Larsen & H. Laudon & M. Lupascu & S. Marhan & J. Mohan & S. Niu & J. J. Peñuelas & I. K. Schmidt & P. H. Templer & G. Kröel-Dulay & S. Frey & M. A. Bradford - 405-405 As a Saudi woman scientist, I’m tired of negative stereotypes
by Malak Abedalthagafi - 411-412 Italian election leaves science out in the cold
by Alison Abbott - 412-413 Physicists plan antimatter’s first outing — in a van
by Elizabeth Gibney - 413-414 Ocean-wide sensor array provides new look at global ocean current
by Jeff Tollefson - 414-415 CRISPR hack transforms cells into data recorders
by Heidi Ledford - 415-416 Indonesian scientists hamstrung by year-long funding delay
by Dyna Rochmyaningsih - 417-419 How to make replication the norm
by Paul Gertler & Sebastian Galiani & Mauricio Romero - 420-422 The limitations of Steven Pinker’s optimism
by Ian Goldin - 421-421 A new light on comets, the embodied brain and a nature cure for dislocation: Books in brief
by Barbara Kiser - 423-423 Use imprint of society and history on climate data to inform climate services
by Stefan Brönnimann & Jeannine Wintzer - 423-423 Solar geoengineering must take temperature debt into account
by Andreas Oschlies - 423-423 Authorship position should not serve as a proxy metric
by Daniel Hornburg - 423-423 Root systems offer insight into better soils
by Doris Vetterlein & Steffen Schlüter & Hans-Jörg Vogel - 426-428 Sex and drugs and self-control: how the teen brain navigates risk
by Kerri Smith - 429-431 Who exactly counts as an adolescent?
by Heidi Ledford - 432-434 Smartphones are bad for some teens, not all
by Candice Odgers - 435-437 Understand the lives of youth in low-income countries
by Robert Blum & Jo Boyden - 438-439 Pruning hypothesis comes of age
by Matthew B. Johnson & Beth Stevens - 441-450 Importance of investing in adolescence from a developmental science perspective
by Ronald E. Dahl & Nicholas B. Allen & Linda Wilbrecht & Ahna Ballonoff Suleiman - 451-457 Dynamics of body time, social time and life history at adolescence
by Carol M. Worthman & Kathy Trang - 458-466 Adolescence and the next generation
by George C. Patton & Craig A. Olsson & Vegard Skirbekk & Richard Saffery & Mary E. Wlodek & Peter S. Azzopardi & Marcin Stonawski & Bruce Rasmussen & Elizabeth Spry & Kate Francis & Zulfiqar A. Bhutta & Nicholas J. Kassebaum & Ali H. Mokdad & Christopher J. L. Murray & Andrew M. Prentice & Nicola Reavley & Peter Sheehan & Kim Sweeny & Russell M. Viner & Susan M. Sawyer - 468-469 Molecules pressured to react
by Stuart L. James - 469-470 Force-activated ion channels in close-up
by Yuh Nung Jan & Lily Yeh Jan - 470-472 An inflammatory transcriptional switch
by L. Charles Murtaugh & Raymond J. MacDonald - 472-473 Neurons mimicked by electronics
by Da Li & Xiaogan Liang - 475-480 A molecular atlas of cell types and zonation in the brain vasculature
by Michael Vanlandewijck & Liqun He & Maarja Andaloussi Mäe & Johanna Andrae & Koji Ando & Francesca Del Gaudio & Khayrun Nahar & Thibaud Lebouvier & Bàrbara Laviña & Leonor Gouveia & Ying Sun & Elisabeth Raschperger & Markus Räsänen & Yvette Zarb & Naoki Mochizuki & Annika Keller & Urban Lendahl & Christer Betsholtz - 481-486 Structure of the mechanically activated ion channel Piezo1
by Kei Saotome & Swetha E. Murthy & Jennifer M. Kefauver & Tess Whitwam & Ardem Patapoutian & Andrew B. Ward - 487-492 Structure and mechanogating mechanism of the Piezo1 channel
by Qiancheng Zhao & Heng Zhou & Shaopeng Chi & Yanfeng Wang & Jianhua Wang & Jie Geng & Kun Wu & Wenhao Liu & Tingxin Zhang & Meng-Qiu Dong & Jiawei Wang & Xueming Li & Bailong Xiao - 493-496 A clumpy and anisotropic galaxy halo at redshift 1 from gravitational-arc tomography
by Sebastian Lopez & Nicolas Tejos & Cédric Ledoux & L. Felipe Barrientos & Keren Sharon & Jane R. Rigby & Michael D. Gladders & Matthew B. Bayliss & Ismael Pessa - 497-499 A surge of light at the birth of a supernova
by M. C. Bersten & G. Folatelli & F. García & S. D. Van Dyk & O. G. Benvenuto & M. Orellana & V. Buso & J. L. Sánchez & M. Tanaka & K. Maeda & A. V. Filippenko & W. Zheng & T. G. Brink & S. B. Cenko & T. de Jaeger & S. Kumar & T. J. Moriya & K. Nomoto & D. A. Perley & I. Shivvers & N. Smith - 500-504 Multi-terminal memtransistors from polycrystalline monolayer molybdenum disulfide
by Vinod K. Sangwan & Hong-Sub Lee & Hadallia Bergeron & Itamar Balla & Megan E. Beck & Kan-Sheng Chen & Mark C. Hersam - 505-510 Sterically controlled mechanochemistry under hydrostatic pressure
by Hao Yan & Fan Yang & Ding Pan & Yu Lin & J. Nathan Hohman & Diego Solis-Ibarra & Fei Hua Li & Jeremy E. P. Dahl & Robert M. K. Carlson & Boryslav A. Tkachenko & Andrey A. Fokin & Peter R. Schreiner & Giulia Galli & Wendy L. Mao & Zhi-Xun Shen & Nicholas A. Melosh - 511-514 Palladium-catalysed electrophilic aromatic C–H fluorination
by Kumiko Yamamoto & Jiakun Li & Jeffrey A. O. Garber & Julian D. Rolfes & Gregory B. Boursalian & Jannik C. Borghs & Christophe Genicot & Jérôme Jacq & Maurice van Gastel & Frank Neese & Tobias Ritter - 515-518 Meridional overturning circulation conveys fast acidification to the deep Atlantic Ocean
by Fiz F. Perez & Marcos Fontela & Maribel I. García-Ibáñez & Herlé Mercier & Anton Velo & Pascale Lherminier & Patricia Zunino & Mercedes de la Paz & Fernando Alonso-Pérez & Elisa F. Guallart & Xose A. Padin - 519-522 Global patterns of tropical forest fragmentation
by Franziska Taubert & Rico Fischer & Jürgen Groeneveld & Sebastian Lehmann & Michael S. Müller & Edna Rödig & Thorsten Wiegand & Andreas Huth - 523-527 Tissue stiffening coordinates morphogenesis by triggering collective cell migration in vivo
by Elias H. Barriga & Kristian Franze & Guillaume Charras & Roberto Mayor - 528-532 Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis
by João M. Monteiro & Ana R. Pereira & Nathalie T. Reichmann & Bruno M. Saraiva & Pedro B. Fernandes & Helena Veiga & Andreia C. Tavares & Margarida Santos & Maria T. Ferreira & Vânia Macário & Michael S. VanNieuwenhze & Sérgio R. Filipe & Mariana G. Pinho - 533-537 Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas
by Isidoro Cobo & Paola Martinelli & Marta Flández & Latifa Bakiri & Mingfeng Zhang & Enrique Carrillo-de-Santa-Pau & Jinping Jia & Víctor J. Sánchez-Arévalo Lobo & Diego Megías & Irene Felipe & Natalia del Pozo & Irene Millán & Liv Thommesen & Torunn Bruland & Sara H. Olson & Jill Smith & Kristina Schoonjans & William R. Bamlet & Gloria M. Petersen & Núria Malats & Laufey T. Amundadottir & Erwin F. Wagner & Francisco X. Real - 538-543 TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
by Daniele V. F. Tauriello & Sergio Palomo-Ponce & Diana Stork & Antonio Berenguer-Llergo & Jordi Badia-Ramentol & Mar Iglesias & Marta Sevillano & Sales Ibiza & Adrià Cañellas & Xavier Hernando-Momblona & Daniel Byrom & Joan A. Matarin & Alexandre Calon & Elisa I. Rivas & Angel R. Nebreda & Antoni Riera & Camille Stephan-Otto Attolini & Eduard Batlle - 544-548 TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
by Sanjeev Mariathasan & Shannon J. Turley & Dorothee Nickles & Alessandra Castiglioni & Kobe Yuen & Yulei Wang & Edward E. Kadel III & Hartmut Koeppen & Jillian L. Astarita & Rafael Cubas & Suchit Jhunjhunwala & Romain Banchereau & Yagai Yang & Yinghui Guan & Cecile Chalouni & James Ziai & Yasin Şenbabaoğlu & Stephen Santoro & Daniel Sheinson & Jeffrey Hung & Jennifer M. Giltnane & Andrew A. Pierce & Kathryn Mesh & Steve Lianoglou & Johannes Riegler & Richard A. D. Carano & Pontus Eriksson & Mattias Höglund & Loan Somarriba & Daniel L. Halligan & Michiel S. van der Heijden & Yohann Loriot & Jonathan E. Rosenberg & Lawrence Fong & Ira Mellman & Daniel S. Chen & Marjorie Green & Christina Derleth & Gregg D. Fine & Priti S. Hegde & Richard Bourgon & Thomas Powles - 549-553 MEK drives BRAF activation through allosteric control of KSR proteins
by Hugo Lavoie & Malha Sahmi & Pierre Maisonneuve & Sara A. Marullo & Neroshan Thevakumaran & Ting Jin & Igor Kurinov & Frank Sicheri & Marc Therrien - 554-554 Correction: Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors
by Fumiji Saito & Kouyuki Hirayasu & Takeshi Satoh & Christian W. Wang & John Lusingu & Takao Arimori & Kyoko Shida & Nirianne Marie Q. Palacpac & Sawako Itagaki & Shiroh Iwanaga & Eizo Takashima & Takafumi Tsuboi & Masako Kohyama & Tadahiro Suenaga & Marco Colonna & Junichi Takagi & Thomas Lavstsen & Toshihiro Horii & Hisashi Arase - 554-554 Correction: Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer
by Amaia Zabala-Letona & Amaia Arruabarrena-Aristorena & Natalia Martín-Martín & Sonia Fernandez-Ruiz & James D. Sutherland & Michelle Clasquin & Julen Tomas-Cortazar & Jose Jimenez & Ines Torres & Phong Quang & Pilar Ximenez-Embun & Ruzica Bago & Aitziber Ugalde-Olano & Ana Loizaga-Iriarte & Isabel Lacasa-Viscasillas & Miguel Unda & Verónica Torrano & Diana Cabrera & Sebastiaan M. van Liempd & Ylenia Cendon & Elena Castro & Stuart Murray & Ajinkya Revandkar & Andrea Alimonti & Yinan Zhang & Amelia Barnett & Gina Lein & David Pirman & Ana R. Cortazar & Leire Arreal & Ludmila Prudkin & Ianire Astobiza & Lorea Valcarcel-Jimenez & Patricia Zuñiga-García & Itziar Fernandez-Dominguez & Marco Piva & Alfredo Caro-Maldonado & Pilar Sánchez-Mosquera & Mireia Castillo-Martín & Violeta Serra & Naiara Beraza & Antonio Gentilella & George Thomas & Mikel Azkargorta & Felix Elortza & Rosa Farràs & David Olmos & Alejo Efeyan & Juan Anguita & Javier Muñoz & Juan M. Falcón-Pérez & Rosa Barrio & Teresa Macarulla & Jose M. Mato & Maria L. Martinez-Chantar & Carlos Cordon-Cardo & Ana M. Aransay & Kevin Marks & José Baselga & Josep Tabernero & Paolo Nuciforo & Brendan D. Manning & Katya Marjon & Arkaitz Carracedo - 555-557 Deep learning for biology
by Sarah Webb - 559-561 Teen spirit in the lab
by Chris Woolston - 564-564 A rossum’s best friend
by Alvaro Zinos-Amaro
February 2018, Volume 554, Issue 7692
- 277-277 Train PhD students to be thinkers not just specialists
by Gundula Bosch - 283-284 Tree rings reveal increased fire risk for southwestern US
by Cally Carswell - 284-285 Trump science budget sows confusion
by Lauren Morello & Giorgia Guglielmi & Sara Reardon & Jeff Tollefson & Alexandra Witze - 286-286 Wild primates threaten efforts to wipe out skin disease
by Lucas Laursen - 286-287 Deluge of astronomical data will soon hit South Africa
by Sarah Wild - 287-288 US science agency will require universities to report sexual harassment
by Alexandra Witze - 289-292 The quantum internet has arrived (and it hasn’t)
by Davide Castelvecchi - 293-295 Find drugs that delay many diseases of old age
by Ilaria Bellantuono - 296-297 The past, present and future of human evolution
by María Martinón-Torres - 298-299 How poets and filmmakers construe complexity at the Crick Institute
by Philip Ball - 299-299 Humanizing the digital revolution, the secret life of yeast and Lyme disease through a climate lens: Books in brief
by Barbara Kiser - 300-300 Japanese photo of Rosalind Franklin unearthed
by Yoshihiko Watanabe - 300-300 Better management of groundwater needed in Pakistan
by Muhammad Arif Watto & Safdar Bashir & Nabeel Khan Niazi - 300-300 Teach young scientists the importance of societal impact for research
by Sascha Friesike & Benedikt Fecher & Gert G. Wagner - 300-300 Coordinate international Earth observations for maximum impact
by Barbara J. Ryan - 300-300 US bill illustrates how conservation triage can lead to extinctions
by Guillaume Chapron & Yaffa Epstein & José Vicente López-Bao - 302-303 The origin of pulsating auroras
by Allison N. Jaynes - 303-304 Brainpower boost for birds in large groups
by Andrew Whiten - 304-305 Burst firing sets the stage for depression
by William M. Howe & Paul J. Kenny - 306-307 Working memory freed from the past
by Laura Busse - 307-308 The two faces of a magnetic honeycomb
by Martin Mourigal - 308-309 On the trail of invasive cells in breast cancer
by Douglas S. Micalizzi & Shyamala Maheswaran - 311-316 Genomics of the origin and evolution of Citrus
by Guohong Albert Wu & Javier Terol & Victoria Ibanez & Antonio López-García & Estela Pérez-Román & Carles Borredá & Concha Domingo & Francisco R. Tadeo & Jose Carbonell-Caballero & Roberto Alonso & Franck Curk & Dongliang Du & Patrick Ollitrault & Mikeal L. Roose & Joaquin Dopazo & Frederick G. Gmitter & Daniel S. Rokhsar & Manuel Talon - 317-322 Ketamine blocks bursting in the lateral habenula to rapidly relieve depression
by Yan Yang & Yihui Cui & Kangning Sang & Yiyan Dong & Zheyi Ni & Shuangshuang Ma & Hailan Hu - 323-327 Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression
by Yihui Cui & Yan Yang & Zheyi Ni & Yiyan Dong & Guohong Cai & Alexandre Foncelle & Shuangshuang Ma & Kangning Sang & Siyang Tang & Yuezhou Li & Ying Shen & Hugues Berry & Shengxi Wu & Hailan Hu - 328-333 Teneurin-3 controls topographic circuit assembly in the hippocampus
by Dominic S. Berns & Laura A. DeNardo & Daniel T. Pederick & Liqun Luo - 334-336 A parsec-scale optical jet from a massive young star in the Large Magellanic Cloud
by Anna F. McLeod & Megan Reiter & Rolf Kuiper & Pamela D. Klaassen & Christopher J. Evans - 337-340 Pulsating aurora from electron scattering by chorus waves
by S. Kasahara & Y. Miyoshi & S. Yokota & T. Mitani & Y. Kasahara & S. Matsuda & A. Kumamoto & A. Matsuoka & Y. Kazama & H. U. Frey & V. Angelopoulos & S. Kurita & K. Keika & K. Seki & I. Shinohara - 341-345 A spin–orbital-entangled quantum liquid on a honeycomb lattice
by K. Kitagawa & T. Takayama & Y. Matsumoto & A. Kato & R. Takano & Y. Kishimoto & S. Bette & R. Dinnebier & G. Jackeli & H. Takagi - 346-350 Freezing on a sphere
by Rodrigo E. Guerra & Colm P. Kelleher & Andrew D. Hollingsworth & Paul M. Chaikin - 351-355 Southern Hemisphere climate variability forced by Northern Hemisphere ice-sheet topography
by T. R. Jones & W. H. G. Roberts & E. J. Steig & K. M. Cuffey & B. R. Markle & J. W. C. White - 356-359 Global patterns of declining temperature variability from the Last Glacial Maximum to the Holocene
by Kira Rehfeld & Thomas Münch & Sze Ling Ho & Thomas Laepple - 360-363 Fluctuating interaction network and time-varying stability of a natural fish community
by Masayuki Ushio & Chih-hao Hsieh & Reiji Masuda & Ethan R Deyle & Hao Ye & Chun-Wei Chang & George Sugihara & Michio Kondoh - 364-367 Cognitive performance is linked to group size and affects fitness in Australian magpies
by Benjamin J. Ashton & Amanda R. Ridley & Emily K. Edwards & Alex Thornton - 368-372 Posterior parietal cortex represents sensory history and mediates its effects on behaviour
by Athena Akrami & Charles D. Kopec & Mathew E. Diamond & Carlos D. Brody - 373-377 c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont
by Mo Xu & Maria Pokrovskii & Yi Ding & Ren Yi & Christy Au & Oliver J. Harrison & Carolina Galan & Yasmine Belkaid & Richard Bonneau & Dan R. Littman - 378-381 Asparagine bioavailability governs metastasis in a model of breast cancer
by Simon R. V. Knott & Elvin Wagenblast & Showkhin Khan & Sun Y. Kim & Mar Soto & Michel Wagner & Marc-Olivier Turgeon & Lisa Fish & Nicolas Erard & Annika L. Gable & Ashley R. Maceli & Steffen Dickopf & Evangelia K. Papachristou & Clive S. D’Santos & Lisa A. Carey & John E. Wilkinson & J. Chuck Harrell & Charles M. Perou & Hani Goodarzi & George Poulogiannis & Gregory J. Hannon - 382-386 Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis
by Yvette C. Wong & Daniel Ysselstein & Dimitri Krainc - 387-391 Structural basis for DNMT3A-mediated de novo DNA methylation
by Zhi-Min Zhang & Rui Lu & Pengcheng Wang & Yang Yu & Dongliang Chen & Linfeng Gao & Shuo Liu & Debin Ji & Scott B Rothbart & Yinsheng Wang & Gang Greg Wang & Jikui Song - 392-392 Correction: Corrigendum: AMPA receptor-mediated regulation of a Gi-protein in cortical neurons
by Yizheng Wang & Daniel L. Small & Danica B. Stanimirovic & Paul Morley & Jon P. Durkin - 392-392 Erratum: Moving beyond microbiome-wide associations to causal microbe identification
by Neeraj K. Surana & Dennis L. Kasper - 392-392 Erratum: Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours
by J. Justin Milner & Clara Toma & Bingfei Yu & Kai Zhang & Kyla Omilusik & Anthony T. Phan & Dapeng Wang & Adam J. Getzler & Toan Nguyen & Shane Crotty & Wei Wang & Matthew E. Pipkin & Ananda W. Goldrath