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Content
January 2019, Volume 565, Issue 7738
- 170-171 Immune cells track hard-to-target brain tumours
by Neeha Zaidi & Elizabeth M. Jaffee - 173-179 Electromagnetic and gravitational responses of photonic Landau levels
by Nathan Schine & Michelle Chalupnik & Tankut Can & Andrey Gromov & Jonathan Simon - 180-185 Thermal stress induces glycolytic beige fat formation via a myogenic state
by Yong Chen & Kenji Ikeda & Takeshi Yoneshiro & Annarita Scaramozza & Kazuki Tajima & Qiang Wang & Kyeongkyu Kim & Kosaku Shinoda & Carlos Henrique Sponton & Zachary Brown & Andrew Brack & Shingo Kajimura - 186-191 De novo design of potent and selective mimics of IL-2 and IL-15
by Daniel-Adriano Silva & Shawn Yu & Umut Y. Ulge & Jamie B. Spangler & Kevin M. Jude & Carlos Labão-Almeida & Lestat R. Ali & Alfredo Quijano-Rubio & Mikel Ruterbusch & Isabel Leung & Tamara Biary & Stephanie J. Crowley & Enrique Marcos & Carl D. Walkey & Brian D. Weitzner & Fátima Pardo-Avila & Javier Castellanos & Lauren Carter & Lance Stewart & Stanley R. Riddell & Marion Pepper & Gonçalo J. L. Bernardes & Michael Dougan & K. Christopher Garcia & David Baker - 192-197 Structural basis of Notch recognition by human γ-secretase
by Guanghui Yang & Rui Zhou & Qiang Zhou & Xuefei Guo & Chuangye Yan & Meng Ke & Jianlin Lei & Yigong Shi - 198-201 The corona contracts in a black-hole transient
by E. Kara & J. F. Steiner & A. C. Fabian & E. M. Cackett & P. Uttley & R. A. Remillard & K. C. Gendreau & Z. Arzoumanian & D. Altamirano & S. Eikenberry & T. Enoto & J. Homan & J. Neilsen & A. L. Stevens - 202-205 Core crystallization and pile-up in the cooling sequence of evolving white dwarfs
by Pier-Emmanuel Tremblay & Gilles Fontaine & Nicola Pietro Gentile Fusillo & Bart H. Dunlap & Boris T. Gänsicke & Mark A. Hollands & J. J. Hermes & Thomas R. Marsh & Elena Cukanovaite & Tim Cunningham - 206-208 A warped disk around an infant protostar
by Nami Sakai & Tomoyuki Hanawa & Yichen Zhang & Aya E. Higuchi & Satoshi Ohashi & Yoko Oya & Satoshi Yamamoto - 209-212 The ultrafast Einstein–de Haas effect
by C. Dornes & Y. Acremann & M. Savoini & M. Kubli & M. J. Neugebauer & E. Abreu & L. Huber & G. Lantz & C. A. F. Vaz & H. Lemke & E. M. Bothschafter & M. Porer & V. Esposito & L. Rettig & M. Buzzi & A. Alberca & Y. W. Windsor & P. Beaud & U. Staub & Diling Zhu & Sanghoon Song & J. M. Glownia & S. L. Johnson - 213-217 Chemical control of structure and guest uptake by a conformationally mobile porous material
by Alexandros P. Katsoulidis & Dmytro Antypov & George F. S. Whitehead & Elliot J. Carrington & Dave J. Adams & Neil G. Berry & George R. Darling & Matthew S. Dyer & Matthew J. Rosseinsky - 218-221 Sound velocity of CaSiO3 perovskite suggests the presence of basaltic crust in the Earth’s lower mantle
by Steeve Gréaux & Tetsuo Irifune & Yuji Higo & Yoshinori Tange & Takeshi Arimoto & Zhaodong Liu & Akihiro Yamada - 222-225 The global distribution and trajectory of tidal flats
by Nicholas J. Murray & Stuart R. Phinn & Michael DeWitt & Renata Ferrari & Renee Johnston & Mitchell B. Lyons & Nicholas Clinton & David Thau & Richard A. Fuller - 226-229 U–Pb-dated flowstones restrict South African early hominin record to dry climate phases
by Robyn Pickering & Andy I. R. Herries & Jon D. Woodhead & John C. Hellstrom & Helen E. Green & Bence Paul & Terrence Ritzman & David S. Strait & Benjamin J. Schoville & Phillip J. Hancox - 230-233 Genomic insights into the 2016–2017 cholera epidemic in Yemen
by François-Xavier Weill & Daryl Domman & Elisabeth Njamkepo & Abdullrahman A. Almesbahi & Mona Naji & Samar Saeed Nasher & Ankur Rakesh & Abdullah M. Assiri & Naresh Chand Sharma & Samuel Kariuki & Mohammad Reza Pourshafie & Jean Rauzier & Abdinasir Abubakar & Jane Y. Carter & Joseph F. Wamala & Caroline Seguin & Christiane Bouchier & Thérèse Malliavin & Bita Bakhshi & Hayder H. N. Abulmaali & Dhirendra Kumar & Samuel M. Njoroge & Mamunur Rahman Malik & John Kiiru & Francisco J. Luquero & Andrew S. Azman & Thandavarayan Ramamurthy & Nicholas R. Thomson & Marie-Laure Quilici - 234-239 Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
by Derin B. Keskin & Annabelle J. Anandappa & Jing Sun & Itay Tirosh & Nathan D. Mathewson & Shuqiang Li & Giacomo Oliveira & Anita Giobbie-Hurder & Kristen Felt & Evisa Gjini & Sachet A. Shukla & Zhuting Hu & Letitia Li & Phuong M. Le & Rosa L. Allesøe & Alyssa R. Richman & Monika S. Kowalczyk & Sara Abdelrahman & Jack E. Geduldig & Sarah Charbonneau & Kristine Pelton & J. Bryan Iorgulescu & Liudmila Elagina & Wandi Zhang & Oriol Olive & Christine McCluskey & Lars R. Olsen & Jonathan Stevens & William J. Lane & Andres M. Salazar & Heather Daley & Patrick Y. Wen & E. Antonio Chiocca & Maegan Harden & Niall J. Lennon & Stacey Gabriel & Gad Getz & Eric S. Lander & Aviv Regev & Jerome Ritz & Donna Neuberg & Scott J. Rodig & Keith L. Ligon & Mario L. Suvà & Kai W. Wucherpfennig & Nir Hacohen & Edward F. Fritsch & Kenneth J. Livak & Patrick A. Ott & Catherine J. Wu & David A. Reardon - 240-245 Actively personalized vaccination trial for newly diagnosed glioblastoma
by Norbert Hilf & Sabrina Kuttruff-Coqui & Katrin Frenzel & Valesca Bukur & Stefan Stevanović & Cécile Gouttefangeas & Michael Platten & Ghazaleh Tabatabai & Valerie Dutoit & Sjoerd H. Burg & Per thor Straten & Francisco Martínez-Ricarte & Berta Ponsati & Hideho Okada & Ulrik Lassen & Arie Admon & Christian H. Ottensmeier & Alexander Ulges & Sebastian Kreiter & Andreas Deimling & Marco Skardelly & Denis Migliorini & Judith R. Kroep & Manja Idorn & Jordi Rodon & Jordi Piró & Hans S. Poulsen & Bracha Shraibman & Katy McCann & Regina Mendrzyk & Martin Löwer & Monika Stieglbauer & Cedrik M. Britten & David Capper & Marij J. P. Welters & Juan Sahuquillo & Katharina Kiesel & Evelyna Derhovanessian & Elisa Rusch & Lukas Bunse & Colette Song & Sandra Heesch & Claudia Wagner & Alexandra Kemmer-Brück & Jörg Ludwig & John C. Castle & Oliver Schoor & Arbel D. Tadmor & Edward Green & Jens Fritsche & Miriam Meyer & Nina Pawlowski & Sonja Dorner & Franziska Hoffgaard & Bernhard Rössler & Dominik Maurer & Toni Weinschenk & Carsten Reinhardt & Christoph Huber & Hans-Georg Rammensee & Harpreet Singh-Jasuja & Ugur Sahin & Pierre-Yves Dietrich & Wolfgang Wick - 246-250 Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery
by Minako Ito & Kyoko Komai & Setsuko Mise-Omata & Mana Iizuka-Koga & Yoshiko Noguchi & Taisuke Kondo & Ryota Sakai & Kazuhiko Matsuo & Takashi Nakayama & Osamu Yoshie & Hiroko Nakatsukasa & Shunsuke Chikuma & Takashi Shichita & Akihiko Yoshimura - 251-254 Genomic encoding of transcriptional burst kinetics
by Anton J. M. Larsson & Per Johnsson & Michael Hagemann-Jensen & Leonard Hartmanis & Omid R. Faridani & Björn Reinius & Åsa Segerstolpe & Chloe M. Rivera & Bing Ren & Rickard Sandberg - 255-257 How four winning mentors help to build skills and dispel doubt
by Chris Woolston - 257-257 Three steps to landing an undergraduate research internship
by Ruth Gotian & Ushma S. Neill - 260-260 Tomorrow, the sunset will be blue
by Jeremy Szal
January 2019, Volume 565, Issue 7737
- 1-1 Author Correction: Reassessing evidence of life in 3,700-million-year-old rocks of Greenland
by Abigail C. Allwood & Minik T. Rosing & David T. Flannery & Joel A. Hurowitz & Christopher M. Heirwegh - 2-2 Author Correction: Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1
by Teerawat Wiwatpanit & Sarah M. Lorenzen & Jorge A. Cantú & Chuan Zhi Foo & Ann K. Hogan & Freddie Márquez & John C. Clancy & Matthew J. Schipma & Mary Ann Cheatham & Anne Duggan & Jaime García-Añoveros - 3-3 Author Correction: Autophagy maintains tumour growth through circulating arginine
by Laura Poillet-Perez & Xiaoqi Xie & Le Zhan & Yang Yang & Daniel W. Sharp & Zhixian Sherrie Hu & Xiaoyang Su & Anurag Maganti & Cherry Jiang & Wenyun Lu & Haiyan Zheng & Marcus W. Bosenberg & Janice M. Mehnert & Jessie Yanxiang Guo & Edmund Lattime & Joshua D. Rabinowitz & Eileen White - 6-6 How to make the next Green New Deal work
by Edward B. Barbier - 9-10 Japan’s pioneering detector set to join hunt for gravitational waves
by Davide Castelvecchi - 11-11 Political upheaval in Nicaragua leaves scientists under siege
by Michele Catanzaro - 12-12 First hint of near-room-temperature superconductor tantalizes physicists
by Davide Castelvecchi - 13-14 What to expect in 2019: science in the new year
by Elizabeth Gibney - 15-18 How ‘magic angle’ graphene is stirring up physics
by Elizabeth Gibney - 19-21 Collapsing glaciers threaten Asia’s water supplies
by Jing Gao & Tandong Yao & Valérie Masson-Delmotte & Hans Christian Steen-Larsen & Weicai Wang - 22-24 Hot tickets for scientists in 2019: Nature’s pick of the cultural calendar
by Nicola Jones - 25-25 Rwanda’s gains from linking science and policy
by Clarisse Musanabaganwa & Jeanine U. Condo & Michael J. Penkunas & Colin Pillai & Edouard Mills - 25-25 Islands’ institutes band together against climate change
by Joanna Newman - 25-25 No female mice or cells? NIH reviewers still might score grant OK
by Nicole C. Woitowich & Teresa K. Woodruff - 25-25 Gene drives: yelling match drowns out marginalized voices
by Natalie Kofler - 28-29 Enzymes engineered to trap reaction intermediates
by Andrew M. Gulick - 29-31 All for one and one for all to fight flu
by Gary J. Nabel & John W. Shiver - 31-32 Methane beneath Greenland’s ice sheet is being released
by Lauren C. Andrews - 32-33 Topological properties controlled by light
by Young-Woo Son - 33-34 Metabolism reprogrammed by the nitric oxide signalling molecule
by Charles J. Lowenstein - 35-42 Scalable energy-efficient magnetoelectric spin–orbit logic
by Sasikanth Manipatruni & Dmitri E. Nikonov & Chia-Ching Lin & Tanay A. Gosavi & Huichu Liu & Bhagwati Prasad & Yen-Lin Huang & Everton Bonturim & Ramamoorthy Ramesh & Ian A. Young - 43-48 Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
by Jeffrey J. Ishizuka & Robert T. Manguso & Collins K. Cheruiyot & Kevin Bi & Arpit Panda & Arvin Iracheta-Vellve & Brian C. Miller & Peter P. Du & Kathleen B. Yates & Juan Dubrot & Ilana Buchumenski & Dawn E. Comstock & Flavian D. Brown & Austin Ayer & Ian C. Kohnle & Hans W. Pope & Margaret D. Zimmer & Debattama R. Sen & Sarah K. Lane-Reticker & Emily J. Robitschek & Gabriel K. Griffin & Natalie B. Collins & Adrienne H. Long & John G. Doench & David Kozono & Erez Y. Levanon & W. Nicholas Haining - 49-55 Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
by Yuanchen Dong & Shuwen Zhang & Zhaolong Wu & Xuemei Li & Wei Li Wang & Yanan Zhu & Svetla Stoilova-McPhie & Ying Lu & Daniel Finley & Youdong Mao - 56-60 Direct observation of incommensurate magnetism in Hubbard chains
by Guillaume Salomon & Joannis Koepsell & Jayadev Vijayan & Timon A. Hilker & Jacopo Nespolo & Lode Pollet & Immanuel Bloch & Christian Gross - 61-66 An ultrafast symmetry switch in a Weyl semimetal
by Edbert J. Sie & Clara M. Nyby & C. D. Pemmaraju & Su Ji Park & Xiaozhe Shen & Jie Yang & Matthias C. Hoffmann & B. K. Ofori-Okai & Renkai Li & Alexander H. Reid & Stephen Weathersby & Ehren Mannebach & Nathan Finney & Daniel Rhodes & Daniel Chenet & Abhinandan Antony & Luis Balicas & James Hone & Thomas P. Devereaux & Tony F. Heinz & Xijie Wang & Aaron M. Lindenberg - 67-72 Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
by Ruijie K. Zhang & Kai Chen & Xiongyi Huang & Lena Wohlschlager & Hans Renata & Frances H. Arnold - 73-77 Greenland melt drives continuous export of methane from the ice-sheet bed
by Guillaume Lamarche-Gagnon & Jemma L. Wadham & Barbara Sherwood Lollar & Sandra Arndt & Peer Fietzek & Alexander D. Beaton & Andrew J. Tedstone & Jon Telling & Elizabeth A. Bagshaw & Jon R. Hawkings & Tyler J. Kohler & Jakub D. Zarsky & Matthew C. Mowlem & Alexandre M. Anesio & Marek Stibal - 78-81 Capture of nebular gases during Earth’s accretion is preserved in deep-mantle neon
by Curtis D. Williams & Sujoy Mukhopadhyay - 82-85 Late Middle Pleistocene Levallois stone-tool technology in southwest China
by Yue Hu & Ben Marwick & Jia-Fu Zhang & Xue Rui & Ya-Mei Hou & Jian-Ping Yue & Wen-Rong Chen & Wei-Wen Huang & Bo Li - 86-90 Identifying the pathways required for coping behaviours associated with sustained pain
by Tianwen Huang & Shing-Hong Lin & Nathalie M. Malewicz & Yan Zhang & Ying Zhang & Martyn Goulding & Robert H. LaMotte & Qiufu Ma - 91-95 A male-expressed rice embryogenic trigger redirected for asexual propagation through seeds
by Imtiyaz Khanday & Debra Skinner & Bing Yang & Raphael Mercier & Venkatesan Sundaresan - 96-100 Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury
by Hua-Lin Zhou & Rongli Zhang & Puneet Anand & Colin T. Stomberski & Zhaoxia Qian & Alfred Hausladen & Liwen Wang & Eugene P. Rhee & Samir M. Parikh & S. Ananth Karumanchi & Jonathan S. Stamler - 101-105 Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity
by Peer W. F. Karmaus & Xiang Chen & Seon Ah Lim & Andrés A. Herrada & Thanh-Long M. Nguyen & Beisi Xu & Yogesh Dhungana & Sherri Rankin & Wenan Chen & Celeste Rosencrance & Kai Yang & Yiping Fan & Yong Cheng & John Easton & Geoffrey Neale & Peter Vogel & Hongbo Chi - 106-111 Programmable design of orthogonal protein heterodimers
by Zibo Chen & Scott E. Boyken & Mengxuan Jia & Florian Busch & David Flores-Solis & Matthew J. Bick & Peilong Lu & Zachary L. VanAernum & Aniruddha Sahasrabuddhe & Robert A. Langan & Sherry Bermeo & T. J. Brunette & Vikram Khipple Mulligan & Lauren P. Carter & Frank DiMaio & Nikolaos G. Sgourakis & Vicki H. Wysocki & David Baker - 112-117 Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid
by Nicolas Huguenin-Dezot & Diego A. Alonzo & Graham W. Heberlig & Mohan Mahesh & Duy P. Nguyen & Mark H. Dornan & Christopher N. Boddy & T. Martin Schmeing & Jason W. Chin - 118-121 Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
by Wilson Wong & Rick Huang & Sebastien Menant & Chuan Hong & Jarrod J. Sandow & Richard W. Birkinshaw & Julie Healer & Anthony N. Hodder & Usheer Kanjee & Christopher J. Tonkin & Denise Heckmann & Vladislav Soroka & Teit Max Moscote Søgaard & Thomas Jørgensen & Manoj T. Duraisingh & Peter E. Czabotar & Willem A. Jongh & Wai-Hong Tham & Andrew I. Webb & Zhiheng Yu & Alan F. Cowman - 123-124 Five innovative ways to use 3D printing in the laboratory
by Andrew Silver - 125-126 Why a postdoc might not advance your career
by Chris Woolston - 126-126 Female authors draw more student readers than do male authors
by Virginia Gewin - 126-126 Film and television tell children who can be scientists
by Virginia Gewin - 128-128 Cold memories
by Laurence Raphael Brothers
December 2018, Volume 564, Issue 7736
- 18-26 Elasticity of lower-mantle bridgmanite
by Jung-Fu Lin & Zhu Mao & Jing Yang & Suyu Fu - 27-31 Kurnosov et al. reply
by A. Kurnosov & H. Marquardt & D. J. Frost & T. Boffa Ballaran & L. Ziberna - 32-34 Concerns about modelling of the EDGES data
by Richard Hills & Girish Kulkarni & P. Daniel Meerburg & Ewald Puchwein - 35-35 Reply to Hills et al
by Judd D. Bowman & Alan E. E. Rogers & Raul A. Monsalve & Thomas J. Mozdzen & Nivedita Mahesh - 36-36 Author Correction: Rock fluidization during peak-ring formation of large impact structures
by Ulrich Riller & Michael H. Poelchau & Auriol S. P. Rae & Felix M. Schulte & Gareth S. Collins & H. Jay Melosh & Richard A. F. Grieve & Joanna V. Morgan & Sean P. S. Gulick & Johanna Lofi & Abdoulaye Diaw & Naoma McCall & David A. Kring - 37-37 Author Correction: The selective tRNA aminoacylation mechanism based on a single G•U pair
by Masahiro Naganuma & Shun-ichi Sekine & Yeeting Esther Chong & Min Guo & Xiang-Lei Yang & Howard Gamper & Ya-Ming Hou & Paul Schimmel & Shigeyuki Yokoyama - 38-38 Publisher Correction: Very-high-energy particle acceleration powered by the jets of the microquasar SS 433
by A. U. Abeysekara & A. Albert & R. Alfaro & C. Alvarez & J. D. Álvarez & R. Arceo & J. C. Arteaga-Velázquez & D. Avila Rojas & H. A. Ayala Solares & E. Belmont-Moreno & S. Y. BenZvi & C. Brisbois & K. S. Caballero-Mora & T. Capistrán & A. Carramiñana & S. Casanova & M. Castillo & U. Cotti & J. Cotzomi & S. Coutiño de León & C. De León & E. De la Fuente & J. C. Díaz-Vélez & S. Dichiara & B. L. Dingus & M. A. DuVernois & R. W. Ellsworth & K. Engel & C. Espinoza & K. Fang & H. Fleischhack & N. Fraija & A. Galván-Gámez & J. A. García-González & F. Garfias & A. González-Muñoz & M. M. González & J. A. Goodman & Z. Hampel-Arias & J. P. Harding & S. Hernandez & J. Hinton & B. Hona & F. Hueyotl-Zahuantitla & C. M. Hui & P. Hüntemeyer & A. Iriarte & A. Jardin-Blicq & V. Joshi & S. Kaufmann & P. Kar & G. J. Kunde & R. J. Lauer & W. H. Lee & H. León Vargas & H. Li & J. T. Linnemann & A. L. Longinotti & G. Luis-Raya & R. López-Coto & K. Malone & S. S. Marinelli & O. Martinez & I. Martinez-Castellanos & J. Martínez-Castro & J. A. Matthews & P. Miranda-Romagnoli & E. Moreno & M. Mostafá & A. Nayerhoda & L. Nellen & M. Newbold & M. U. Nisa & R. Noriega-Papaqui & J. Pretz & E. G. Pérez-Pérez & Z. Ren & C. D. Rho & C. Rivière & D. Rosa-González & M. Rosenberg & E. Ruiz-Velasco & F. Salesa Greus & A. Sandoval & M. Schneider & H. Schoorlemmer & M. Seglar Arroyo & G. Sinnis & A. J. Smith & R. W. Springer & P. Surajbali & I. Taboada & O. Tibolla & K. Tollefson & I. Torres & G. Vianello & L. Villaseñor & T. Weisgarber & F. Werner & S. Westerhoff & J. Wood & T. Yapici & G. Yodh & A. Zepeda & H. Zhang & H. Zhou - 73-73 Liver cirrhosis: scar wars
by Liam Drew - 74-75 Tipping the balance
by Liam Drew - 79-79 The 2019 Events Guide
by Jack Leeming - 80-82 The future of the scientific conference
by Emily Sohn - 84-85 How to give a great scientific talk
by Nic Fleming - 86-87 Milestone meetings
by Virginia Gewin - 88-89 How conferences are getting better at accommodating child-caring scientists
by Julie Gould - 89-89 Make it easier for me to deliver childcare at conferences
by Eileen Parkes - 303-303 How I stave off despair as a climate scientist
by Dave Reay - 309-310 South Korean scientists protest treatment of university president accused of misusing funds
by Mark Zastrow - 310-311 Italian scientists protest funding for vaccine-safety investigation
by Giorgia Guglielmi - 311-312 Massive ocean carbon sink spotted burping CO2 on the sly
by Jeff Tollefson - 312-312 China introduces ‘social’ punishments for scientific misconduct
by David Cyranoski - 314-317 2018 in news: The science events that shaped the year
by Alison Abbott & Ewen Callaway & Davide Castelvecchi & Holly Else & Elizabeth Gibney & Heidi Ledford & Jane J. Lee & Lauren Morello & Jeff Tollefson & Alexandra Witze - 318-323 The best science images of the year: 2018 in pictures
by Mico Tatalovic - 325-335 Nature’s 10: Ten people who mattered in science in 2018
by Elizabeth Gibney & Ewen Callaway & David Cyranoski & Nisha Gaind & Jeff Tollefson & Rachel Courtland & Yao-Hua Law & Brendan Maher & Holly Else & Davide Castelvecchi - 337-339 Vaccine candidates for poor nations are going to waste
by David C. Kaslow & Steve Black & David E. Bloom & Mahima Datla & David Salisbury & Rino Rappuoli - 340-342 Explorers at sea: centuries of science afloat
by Huw Lewis-Jones - 345-345 Up for debate — WHO guidelines on prompt release of outbreak data
by Vasee Moorthy & Peter Salama & Soumya Swaminathan - 345-345 CRISPR twins: a condemnation from Chinese academic societies
by Haoyi Wang & Jinsong Li & Wei Li & Caixia Gao & Wensheng Wei - 345-345 Biodiversity loss is dire, don’t get distracted
by Jonathan Davies & Peter Stoett - 345-345 Gene editing: sloppy definitions mislead
by Paul Knoepfler - 345-345 King Faisal international prize a harbinger of Nobel winners?
by Sameen Ahmed Khan - 346-346 Aaron Klug (1926-2018)
by Kenneth Holmes - 348-349 Tiny crystals have big potential for determining structures of small molecules
by Alan Brown & Jon Clardy - 349-350 Brain circuits of compulsive drug addiction identified
by Patricia Janak - 350-351 Elusive torque sensed by liquid crystals
by Slobodan Žumer - 352-353 Success for pig-to-baboon heart transplants
by Christoph Knosalla - 353-354 An abundance of rare isotopes in a planetary nebula
by Amanda Karakas - 354-355 Amyloid-β ‘seeds’ in old vials of growth hormone
by Tien-Phat V. Huynh & David M. Holtzman - 359-365 Soft-tissue evidence for homeothermy and crypsis in a Jurassic ichthyosaur
by Johan Lindgren & Peter Sjövall & Volker Thiel & Wenxia Zheng & Shosuke Ito & Kazumasa Wakamatsu & Rolf Hauff & Benjamin P. Kear & Anders Engdahl & Carl Alwmark & Mats E. Eriksson & Martin Jarenmark & Sven Sachs & Per E. Ahlberg & Federica Marone & Takeo Kuriyama & Ola Gustafsson & Per Malmberg & Aurélien Thomen & Irene Rodríguez-Meizoso & Per Uvdal & Makoto Ojika & Mary H. Schweitzer - 366-371 Stochastic synaptic plasticity underlying compulsion in a model of addiction
by Vincent Pascoli & Agnès Hiver & Ruud Zessen & Michaël Loureiro & Ridouane Achargui & Masaya Harada & Jérôme Flakowski & Christian Lüscher - 372-377 Structure of native lens connexin 46/50 intercellular channels by cryo-EM
by Janette B. Myers & Bassam G. Haddad & Susan E. O’Neill & Dror S. Chorev & Craig C. Yoshioka & Carol V. Robinson & Daniel M. Zuckerman & Steve L. Reichow - 378-381 Extreme 13C,15N and 17O isotopic enrichment in the young planetary nebula K4-47
by D. R. Schmidt & N. J. Woolf & T. J. Zega & L. M. Ziurys - 382-385 Impact of pear-shaped fission fragments on mass-asymmetric fission in actinides
by Guillaume Scamps & Cédric Simenel - 386-389 Measurement of the Casimir torque
by David A. T. Somers & Joseph L. Garrett & Kevin J. Palm & Jeremy N. Munday - 390-394 Electric-field-tuned topological phase transition in ultrathin Na3Bi
by James L. Collins & Anton Tadich & Weikang Wu & Lidia C. Gomes & Joao N. B. Rodrigues & Chang Liu & Jack Hellerstedt & Hyejin Ryu & Shujie Tang & Sung-Kwan Mo & Shaffique Adam & Shengyuan A. Yang & Michael S. Fuhrer & Mark T. Edmonds - 395-399 Desymmetrization of cyclohexanes by site- and stereoselective C–H functionalization
by Jiantao Fu & Zhi Ren & John Bacsa & Djamaladdin G. Musaev & Huw M. L. Davies - 400-404 Origin of spatial variation in US East Coast sea-level trends during 1900–2017
by Christopher G. Piecuch & Peter Huybers & Carling C. Hay & Andrew C. Kemp & Christopher M. Little & Jerry X. Mitrovica & Rui M. Ponte & Martin P. Tingley - 405-409 Chemical differentiation, cold storage and remobilization of magma in the Earth’s crust
by M. D. Jackson & J. Blundy & R. S. J. Sparks - 410-414 Hemimastigophora is a novel supra-kingdom-level lineage of eukaryotes
by Gordon Lax & Yana Eglit & Laura Eme & Erin M. Bertrand & Andrew J. Roger & Alastair G. B. Simpson - 415-419 Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone
by Silvia A. Purro & Mark A. Farrow & Jacqueline Linehan & Tamsin Nazari & David X. Thomas & Zhicheng Chen & David Mengel & Takashi Saito & Takaomi Saido & Peter Rudge & Sebastian Brandner & Dominic M. Walsh & John Collinge - 420-424 Distinct activity-gated pathways mediate attraction and aversion to CO2 in Drosophila
by Floris Breugel & Ainul Huda & Michael H. Dickinson - 425-429 Complex mammalian-like haematopoietic system found in a colonial chordate
by Benyamin Rosental & Mark Kowarsky & Jun Seita & Daniel M. Corey & Katherine J. Ishizuka & Karla J. Palmeri & Shih-Yu Chen & Rahul Sinha & Jennifer Okamoto & Gary Mantalas & Lucia Manni & Tal Raveh & D. Nathaniel Clarke & Jonathan M. Tsai & Aaron M. Newman & Norma F. Neff & Garry P. Nolan & Stephen R. Quake & Irving L. Weissman & Ayelet Voskoboynik - 430-433 Consistent success in life-supporting porcine cardiac xenotransplantation
by Matthias Längin & Tanja Mayr & Bruno Reichart & Sebastian Michel & Stefan Buchholz & Sonja Guethoff & Alexey Dashkevich & Andrea Baehr & Stefanie Egerer & Andreas Bauer & Maks Mihalj & Alessandro Panelli & Lara Issl & Jiawei Ying & Ann Kathrin Fresch & Ines Buttgereit & Maren Mokelke & Julia Radan & Fabian Werner & Isabelle Lutzmann & Stig Steen & Trygve Sjöberg & Audrius Paskevicius & Liao Qiuming & Riccardo Sfriso & Robert Rieben & Maik Dahlhoff & Barbara Kessler & Elisabeth Kemter & Mayuko Kurome & Valeri Zakhartchenko & Katharina Klett & Rabea Hinkel & Christian Kupatt & Almuth Falkenau & Simone Reu & Reinhard Ellgass & Rudolf Herzog & Uli Binder & Günter Wich & Arne Skerra & David Ayares & Alexander Kind & Uwe Schönmann & Franz-Josef Kaup & Christian Hagl & Eckhard Wolf & Nikolai Klymiuk & Paolo Brenner & Jan-Michael Abicht - 434-438 The translation of non-canonical open reading frames controls mucosal immunity
by Ruaidhrí Jackson & Lina Kroehling & Alexandra Khitun & Will Bailis & Abigail Jarret & Autumn G. York & Omair M. Khan & J. Richard Brewer & Mathias H. Skadow & Coco Duizer & Christian C. D. Harman & Lelina Chang & Piotr Bielecki & Angel G. Solis & Holly R. Steach & Sarah Slavoff & Richard A. Flavell - 439-443 Design of amidobenzimidazole STING receptor agonists with systemic activity
by Joshi M. Ramanjulu & G. Scott Pesiridis & Jingsong Yang & Nestor Concha & Robert Singhaus & Shu-Yun Zhang & Jean-Luc Tran & Patrick Moore & Stephanie Lehmann & H. Christian Eberl & Marcel Muelbaier & Jessica L. Schneck & Jim Clemens & Michael Adam & John Mehlmann & Joseph Romano & Angel Morales & James Kang & Lara Leister & Todd L. Graybill & Adam K. Charnley & Guosen Ye & Neysa Nevins & Kamelia Behnia & Amaya I. Wolf & Viera Kasparcova & Kelvin Nurse & Liping Wang & Ana C. Puhl & Yue Li & Michael Klein & Christopher B. Hopson & Jeffrey Guss & Marcus Bantscheff & Giovanna Bergamini & Michael A. Reilly & Yiqian Lian & Kevin J. Duffy & Jerry Adams & Kevin P. Foley & Peter J. Gough & Robert W. Marquis & James Smothers & Axel Hoos & John Bertin - 444-448 Controlling orthogonal ribosome subunit interactions enables evolution of new function
by Wolfgang H. Schmied & Zakir Tnimov & Chayasith Uttamapinant & Christopher D. Rae & Stephen D. Fried & Jason W. Chin - 449-450 Seven steps to boost your research career in 2019
by Chris Woolston - 462-462 Solstice
by John Gilbey
December 2018, Volume 564, Issue 7735
- 5-5 Gene therapy
by Herb Brody - 6-8 Prenatal gene therapy offers the earliest possible cure
by Sarah DeWeerdt - 9-9 Author Correction: Necroptosis microenvironment directs lineage commitment in liver cancer
by Marco Seehawer & Florian Heinzmann & Luana D’Artista & Jule Harbig & Pierre-François Roux & Lisa Hoenicke & Hien Dang & Sabrina Klotz & Lucas Robinson & Grégory Doré & Nir Rozenblum & Tae-Won Kang & Rishabh Chawla & Thorsten Buch & Mihael Vucur & Mareike Roth & Johannes Zuber & Tom Luedde & Bence Sipos & Thomas Longerich & Mathias Heikenwälder & Xin Wei Wang & Oliver Bischof & Lars Zender - 9-9 A genetically augmented future
by Ellen Wright Clayton - 10-10 Author Correction: Self-organization of a human organizer by combined Wnt and Nodal signalling
by I. Martyn & T. Y. Kanno & A. Ruzo & E. D. Siggia & A. H. Brivanlou - 10-11 Gene therapy targets epilepsy
by Liam Drew - 11-16 Author Correction: A global slowdown of tropical-cyclone translation speed
by James P. Kossin - 12-13 Gene therapy targets sickle-cell disease
by Anna Nowogrodzki - 14-15 Change the genes to fix the skin
by Kat Arney - 16-17 The genetic shortcut to antibody drugs
by Amanda Keener - 17-17 Publisher Correction: Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing
by Binbin Lai & Weiwu Gao & Kairong Cui & Wanli Xie & Qingsong Tang & Wenfei Jin & Gangqing Hu & Bing Ni & Keji Zhao - 18-19 Designer viruses could be the secret to cheaper and better gene therapy
by Neil Savage - 20-22 Regulating the gene-therapy revolution
by Eric Bender - 23-23 Access and affordability for all
by Michael Sherman - 53-55 How Indian biotech is driving innovation
by Bianca Nogrady - 57-57 All eyes on the prize
by Catherine Armitage - 62-63 Yielding results to feed a people
by Hepeng Jia - 64-65 China’s place among the stars
by Mark Zastrow - 65-66 Small science grows large in new hands
by Sarah O’Meara - 66-68 Engineering a biomedical revolution
by Smriti Mallapaty - 68-69 Strong spending compounds chemistry prowess
by Hepeng Jia - 70-71 Quality deficit belies the hype
by Futao Huang - 70-71 Citations strength begins at home
by Vincent Larivière & Kaile Gong & Cassidy R. Sugimoto - 163-163 Students need guidance in languages they speak
by Clarissa Rios Rojas - 169-170 ‘Little Foot’ hominin emerges from stone after millions of years
by Colin Barras - 170-171 Machine learning helps to hunt down the cause of a paralysing illness
by Sara Reardon - 171-172 China backs bold plan to tear down journal paywalls
by Quirin Schiermeier - 172-173 Could the United Kingdom really build its own global satnav system?
by Declan Butler - 173-174 Cancer researchers seek to harness mysterious DNA ‘super-enhancers’
by Heidi Ledford - 174-175 Ebola detectives race to identify hidden sources of infection as outbreak spreads
by Amy Maxmen - 176-179 How the brain’s face code might unlock the mysteries of perception
by Alison Abbott - 180-182 The hunt for life below Antarctic ice
by Douglas Fox - 183-185 Debate ethics of embryo models from stem cells
by Nicolas Rivron & Martin Pera & Janet Rossant & Alfonso Martinez Arias & Magdalena Zernicka-Goetz & Jianping Fu & Susanne van den Brink & Annelien Bredenoord & Wybo Dondorp & Guido de Wert & Insoo Hyun & Megan Munsie & Rosario Isasi - 186-188 India: a turbulent tale of rivers, floods and monsoons
by Philip Ball - 187-187 The Wright brothers’ real story, cosmic chronology, and what happened to the megafauna: Books in brief
by Barbara Kiser - 188-189 Science in hand: how art and craft can boost reproducibility
by Roger Kneebone & Claudia Schlegel & Alan Spivey - 190-190 COP24 and SDGs — use same statistics please
by Francesco N. Tubiello - 190-190 No place for ‘trial by media’ in bullying allegations
by Grace Collord & Jyoti Nangalia & Luiza Moore - 190-190 NIH dollars go to too few US states
by Wayne P. Wahls - 190-190 Gene editing: who should decide?
by Akira Akabayashi & Eisuke Nakazawa & Arthur L. Caplan - 192-193 El Niño events will intensify under global warming
by Yoo-Geun Ham - 193-194 How cells hush a viral invader
by Parinaz Fozouni & Melanie Ott - 194-196 Adrenaline fuels a cytokine storm during immunotherapy
by Stanley R. RIddell - 196-197 Darwin’s finches choose parent lookalikes as mates
by Lewis G. Spurgin & Tracey Chapman - 197-199 An exciting tool for asymmetric synthesis
by Cheng Yang & Yoshihisa Inoue - 199-200 Bacterial defence molecules target viral DNA
by Martha R. J. Clokie - 201-206 Increased variability of eastern Pacific El Niño under greenhouse warming
by Wenju Cai & Guojian Wang & Boris Dewitte & Lixin Wu & Agus Santoso & Ken Takahashi & Yun Yang & Aude Carréric & Michael J. McPhaden - 207-212 Widespread but heterogeneous responses of Andean forests to climate change
by Belén Fadrique & Selene Báez & Álvaro Duque & Agustina Malizia & Cecilia Blundo & Julieta Carilla & Oriana Osinaga-Acosta & Lucio Malizia & Miles Silman & William Farfán-Ríos & Yadvinder Malhi & Kenneth R. Young & Francisco Cuesta C. & Jurgen Homeier & Manuel Peralvo & Esteban Pinto & Oswaldo Jadan & Nikolay Aguirre & Zhofre Aguirre & Kenneth J. Feeley - 213-218 A circuit from hippocampal CA2 to lateral septum disinhibits social aggression
by Felix Leroy & Jung Park & Arun Asok & David H. Brann & Torcato Meira & Lara M. Boyle & Eric W. Buss & Eric R. Kandel & Steven A. Siegelbaum - 219-224 Single-cell mapping of lineage and identity in direct reprogramming
by Brent A. Biddy & Wenjun Kong & Kenji Kamimoto & Chuner Guo & Sarah E. Waye & Tao Sun & Samantha A. Morris - 225-228 An entanglement-based wavelength-multiplexed quantum communication network
by Sören Wengerowsky & Siddarth Koduru Joshi & Fabian Steinlechner & Hannes Hübel & Rupert Ursin - 229-233 Experimental realization of on-chip topological nanoelectromechanical metamaterials
by Jinwoong Cha & Kun Woo Kim & Chiara Daraio - 234-239 Reversible superdense ordering of lithium between two graphene sheets
by Matthias Kühne & Felix Börrnert & Sven Fecher & Mahdi Ghorbani-Asl & Johannes Biskupek & Dominik Samuelis & Arkady V. Krasheninnikov & Ute Kaiser & Jurgen H. Smet - 240-243 Catalytic deracemization of chiral allenes by sensitized excitation with visible light
by Alena Hölzl-Hobmeier & Andreas Bauer & Alexandre Vieira Silva & Stefan M. Huber & Christoph Bannwarth & Thorsten Bach - 244-248 Deconstructive diversification of cyclic amines
by Jose B. Roque & Yusuke Kuroda & Lucas T. Göttemann & Richmond Sarpong - 249-253 Assessing the efficiency of changes in land use for mitigating climate change
by Timothy D. Searchinger & Stefan Wirsenius & Tim Beringer & Patrice Dumas - 254-257 Palaeolithic cave art in Borneo
by M. Aubert & P. Setiawan & A. A. Oktaviana & A. Brumm & P. H. Sulistyarto & E. W. Saptomo & B. Istiawan & T. A. Ma’rifat & V. N. Wahyuono & F. T. Atmoko & J.-X. Zhao & J. Huntley & P. S. C. Taçon & D. L. Howard & H. E. A. Brand - 258-262 Reward behaviour is regulated by the strength of hippocampus–nucleus accumbens synapses
by Tara A. LeGates & Mark D. Kvarta & Jessica R. Tooley & T. Chase Francis & Mary Kay Lobo & Meaghan C. Creed & Scott M. Thompson - 263-267 Trophoblast organoids as a model for maternal–fetal interactions during human placentation
by Margherita Y. Turco & Lucy Gardner & Richard G. Kay & Russell S. Hamilton & Malwina Prater & Michael S. Hollinshead & Alasdair McWhinnie & Laura Esposito & Ridma Fernando & Helen Skelton & Frank Reimann & Fiona M. Gribble & Andrew Sharkey & Steven G. E. Marsh & Stephen O’Rahilly & Myriam Hemberger & Graham J. Burton & Ashley Moffett - 268-272 Lineage tracking reveals dynamic relationships of T cells in colorectal cancer
by Lei Zhang & Xin Yu & Liangtao Zheng & Yuanyuan Zhang & Yansen Li & Qiao Fang & Ranran Gao & Boxi Kang & Qiming Zhang & Julie Y. Huang & Hiroyasu Konno & Xinyi Guo & Yingjiang Ye & Songyuan Gao & Shan Wang & Xueda Hu & Xianwen Ren & Zhanlong Shen & Wenjun Ouyang & Zemin Zhang - 273-277 Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome
by Verena Staedtke & Ren-Yuan Bai & Kibem Kim & Martin Darvas & Marco L. Davila & Gregory J. Riggins & Paul B. Rothman & Nickolas Papadopoulos & Kenneth W. Kinzler & Bert Vogelstein & Shibin Zhou - 278-282 NP220 mediates silencing of unintegrated retroviral DNA
by Yiping Zhu & Gary Z. Wang & Oya Cingöz & Stephen P. Goff - 283-286 A chemical defence against phage infection
by Sarah Kronheim & Martin Daniel-Ivad & Zhuang Duan & Sungwon Hwang & Andrew I. Wong & Ian Mantel & Justin R. Nodwell & Karen L. Maxwell - 287-290 Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks
by Yang Yu & Nhung Pham & Bo Xia & Alma Papusha & Guangyu Wang & Zhenxin Yan & Guang Peng & Kaifu Chen & Grzegorz Ira - 291-292 The automatic-design tools that are changing synthetic biology
by Anna Nowogrodzki - 293-294 The scientists who feed us
by David Payne - 296-296 Cold heart
by Victoria Dixon
December 2018, Volume 564, Issue 7734
- 1-1 Stiff competition
by G. W. Milton - 1-3 Computer logic meets cell biology: how cell science is getting an upgrade
by Neil Savage - 2-4 Berger et al. reply
by J. B. Berger & H. N. G. Wadley & R. M. McMeeking - 5-5 Author Correction: A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes
by Roshni Roy Chowdhury & Francesco Vallania & Qianting Yang & Cesar Joel Lopez Angel & Fatoumatta Darboe & Adam Penn-Nicholson & Virginie Rozot & Elisa Nemes & Stephanus T. Malherbe & Katharina Ronacher & Gerhard Walzl & Willem Hanekom & Mark M. Davis & Jill Winter & Xinchun Chen & Thomas J. Scriba & Purvesh Khatri & Yueh-hsiu Chien - 6-6 Author Correction: Cryo-EM of the dynamin polymer assembled on lipid membrane
by Leopold Kong & Kem A. Sochacki & Huaibin Wang & Shunming Fang & Bertram Canagarajah & Andrew D. Kehr & William J. Rice & Marie-Paule Strub & Justin W. Taraska & Jenny E. Hinshaw - 7-7 How sure are you of your result? Put a number on it
by Steven N. Goodman - 7-7 Publisher Correction: Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease
by Sandro Da Mesquita & Antoine Louveau & Andrea Vaccari & Igor Smirnov & R. Chase Cornelison & Kathryn M. Kingsmore & Christian Contarino & Suna Onengut-Gumuscu & Emily Farber & Daniel Raper & Kenneth E. Viar & Romie D. Powell & Wendy Baker & Nisha Dabhi & Robin Bai & Rui Cao & Song Hu & Stephen S. Rich & Jennifer M. Munson & M. Beatriz Lopes & Christopher C. Overall & Scott T. Acton & Jonathan Kipnis - 8-8 Publisher Correction: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys
by Erica N. Borducchi & Jinyan Liu & Joseph P. Nkolola & Anthony M. Cadena & Wen-Han Yu & Stephanie Fischinger & Thomas Broge & Peter Abbink & Noe B. Mercado & Abishek Chandrashekar & David Jetton & Lauren Peter & Katherine McMahan & Edward T. Moseley & Elena Bekerman & Joseph Hesselgesser & Wenjun Li & Mark G. Lewis & Galit Alter & Romas Geleziunas & Dan H. Barouch - 13-14 CRISPR-baby scientist fails to satisfy critics
by David Cyranoski - 15-15 China set to launch first-ever spacecraft to the far side of the Moon
by Andrew Silver - 16-16 Venice anti-flood gates could wreck lagoon ecosystem
by Lou Del Bello - 17-18 Tehran’s drastic sinking exposed by satellite data
by Kate Ravilious