De novo design of potent and selective mimics of IL-2 and IL-15
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DOI: 10.1038/s41586-018-0830-7
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- Namrata Anand & Raphael Eguchi & Irimpan I. Mathews & Carla P. Perez & Alexander Derry & Russ B. Altman & Po-Ssu Huang, 2022. "Protein sequence design with a learned potential," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
- Julia Skokowa & Birte Hernandez Alvarez & Murray Coles & Malte Ritter & Masoud Nasri & Jérémy Haaf & Narges Aghaallaei & Yun Xu & Perihan Mir & Ann-Christin Krahl & Katherine W. Rogers & Kateryna Maks, 2022. "A topological refactoring design strategy yields highly stable granulopoietic proteins," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Sasha B. Ebrahimi & Devleena Samanta, 2023. "Engineering protein-based therapeutics through structural and chemical design," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
- Fabian Sesterhenn & Che Yang & Jaume Bonet & Johannes T. Cramer & Xiaolin Wen & Yimeng Wang & Chi I. Chiang & Luciano Andres Abriata & Iga Kucharska & Giacomo Castoro & Sabrina S. Vollers & Marie Gall, 2020. "De novo protein design enables the precise induction of RSV-neutralizing antibodies," Post-Print hal-02677103, HAL.
- Betz, Ulrich A.K. & Arora, Loukik & Assal, Reem A. & Azevedo, Hatylas & Baldwin, Jeremy & Becker, Michael S. & Bostock, Stefan & Cheng, Vinton & Egle, Tobias & Ferrari, Nicola & Schneider-Futschik, El, 2023. "Game changers in science and technology - now and beyond," Technological Forecasting and Social Change, Elsevier, vol. 193(C).
- Hongxia Zhao & Wenlong Ding & Jia Zang & Yang Yang & Chao Liu & Linzhen Hu & Yulin Chen & Guanglong Liu & Yu Fang & Ying Yuan & Shixian Lin, 2021. "Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction," Nature Communications, Nature, vol. 12(1), pages 1-12, December.
- Seymour Picciotto & Nicholas DeVita & Chiaowen Joyce Hsiao & Christopher Honan & Sze-Wah Tse & Mychael Nguyen & Joseph D. Ferrari & Wei Zheng & Brian T. Wipke & Eric Huang, 2022. "Selective activation and expansion of regulatory T cells using lipid encapsulated mRNA encoding a long-acting IL-2 mutein," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
- Sicong Yao & Adam Moyer & Yiwu Zheng & Yang Shen & Xiaoting Meng & Chong Yuan & Yibing Zhao & Hongwei Yao & David Baker & Chuanliu Wu, 2022. "De novo design and directed folding of disulfide-bridged peptide heterodimers," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
- Buwei Huang & Brian Coventry & Marta T. Borowska & Dimitrios C. Arhontoulis & Marc Exposit & Mohamad Abedi & Kevin M. Jude & Samer F. Halabiya & Aza Allen & Cami Cordray & Inna Goreshnik & Maggie Ahlr, 2024. "De novo design of miniprotein antagonists of cytokine storm inducers," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
- Nathaniel R. Bennett & Brian Coventry & Inna Goreshnik & Buwei Huang & Aza Allen & Dionne Vafeados & Ying Po Peng & Justas Dauparas & Minkyung Baek & Lance Stewart & Frank DiMaio & Steven Munck & Savv, 2023. "Improving de novo protein binder design with deep learning," Nature Communications, Nature, vol. 14(1), pages 1-9, December.
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