Content
August 2018, Volume 560, Issue 7716
- 37-38 Reflection forbidden and refraction reversed in an artificial crystal
by Baile Zhang - 38-39 An unexpected trigger for calorie burning in brown fat
by Sheng Hui & Joshua D. Rabinowitz - 39-40 Developing neurons are innately inclined to learn on the job
by Christian Mayer & Gord Fishell - 41-48 Machine learning at the energy and intensity frontiers of particle physics
by Alexander Radovic & Mike Williams & David Rousseau & Michael Kagan & Daniele Bonacorsi & Alexander Himmel & Adam Aurisano & Kazuhiro Terao & Taritree Wongjirad - 49-54 Genome-centric view of carbon processing in thawing permafrost
by Ben J. Woodcroft & Caitlin M. Singleton & Joel A. Boyd & Paul N. Evans & Joanne B. Emerson & Ahmed A. F. Zayed & Robert D. Hoelzle & Timothy O. Lamberton & Carmody K. McCalley & Suzanne B. Hodgkins & Rachel M. Wilson & Samuel O. Purvine & Carrie D. Nicora & Changsheng Li & Steve Frolking & Jeffrey P. Chanton & Patrick M. Crill & Scott R. Saleska & Virginia I. Rich & Gene W. Tyson - 55-60 Leukaemia hijacks a neural mechanism to invade the central nervous system
by Hisayuki Yao & Trevor T. Price & Gaia Cantelli & Brandon Ngo & Matthew J. Warner & Lindsey Olivere & Sarah M. Ridge & Elizabeth M. Jablonski & Joseph Therrien & Stacey Tannheimer & Chad M. McCall & Anjen Chenn & Dorothy A. Sipkins - 61-64 Topological negative refraction of surface acoustic waves in a Weyl phononic crystal
by Hailong He & Chunyin Qiu & Liping Ye & Xiangxi Cai & Xiying Fan & Manzhu Ke & Fan Zhang & Zhengyou Liu - 65-69 Photoswitching topology in polymer networks with metal–organic cages as crosslinks
by Yuwei Gu & Eric A. Alt & Heng Wang & Xiaopeng Li & Adam P. Willard & Jeremiah A. Johnson - 70-75 Direct arylation of strong aliphatic C–H bonds
by Ian B. Perry & Thomas F. Brewer & Patrick J. Sarver & Danielle M. Schultz & Daniel A. DiRocco & David W. C. MacMillan - 76-79 A two-million-year-long hydroclimatic context for hominin evolution in southeastern Africa
by Thibaut Caley & Thomas Extier & James A. Collins & Enno Schefuß & Lydie Dupont & Bruno Malaizé & Linda Rossignol & Antoine Souron & Erin L. McClymont & Francisco J. Jimenez-Espejo & Carmen García-Comas & Frédérique Eynaud & Philippe Martinez & Didier M. Roche & Stephan J. Jorry & Karine Charlier & Mélanie Wary & Pierre-Yves Gourves & Isabelle Billy & Jacques Giraudeau - 80-83 Globally rising soil heterotrophic respiration over recent decades
by Ben Bond-Lamberty & Vanessa L. Bailey & Min Chen & Christopher M. Gough & Rodrigo Vargas - 84-87 Blue boron-bearing diamonds from Earth’s lower mantle
by Evan M. Smith & Steven B. Shirey & Stephen H. Richardson & Fabrizio Nestola & Emma S. Bullock & Jianhua Wang & Wuyi Wang - 88-91 Hurricane-induced selection on the morphology of an island lizard
by Colin M. Donihue & Anthony Herrel & Anne-Claire Fabre & Ambika Kamath & Anthony J. Geneva & Thomas W. Schoener & Jason J. Kolbe & Jonathan B. Losos - 92-96 Ecosystem restructuring along the Great Barrier Reef following mass coral bleaching
by Rick D. Stuart-Smith & Christopher J. Brown & Daniela M. Ceccarelli & Graham J. Edgar - 97-101 Differential tuning of excitation and inhibition shapes direction selectivity in ferret visual cortex
by Daniel E. Wilson & Benjamin Scholl & David Fitzpatrick - 102-106 Accumulation of succinate controls activation of adipose tissue thermogenesis
by Evanna L. Mills & Kerry A. Pierce & Mark P. Jedrychowski & Ryan Garrity & Sally Winther & Sara Vidoni & Takeshi Yoneshiro & Jessica B. Spinelli & Gina Z. Lu & Lawrence Kazak & Alexander S. Banks & Marcia C. Haigis & Shingo Kajimura & Michael P. Murphy & Steven P. Gygi & Clary B. Clish & Edward T. Chouchani - 107-111 Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides
by Xiaoxiao Wan & Bernd H. Zinselmeyer & Pavel N. Zakharov & Anthony N. Vomund & Ruth Taniguchi & Laura Santambrogio & Mark S. Anderson & Cheryl F. Lichti & Emil R. Unanue - 112-116 53BP1–RIF1–shieldin counteracts DSB resection through CST- and Polα-dependent fill-in
by Zachary Mirman & Francisca Lottersberger & Hiroyuki Takai & Tatsuya Kibe & Yi Gong & Kaori Takai & Alessandro Bianchi & Michal Zimmermann & Daniel Durocher & Titia Lange - 117-121 The shieldin complex mediates 53BP1-dependent DNA repair
by Sylvie M. Noordermeer & Salomé Adam & Dheva Setiaputra & Marco Barazas & Stephen J. Pettitt & Alexanda K. Ling & Michele Olivieri & Alejandro Álvarez-Quilón & Nathalie Moatti & Michal Zimmermann & Stefano Annunziato & Dragomir B. Krastev & Feifei Song & Inger Brandsma & Jessica Frankum & Rachel Brough & Alana Sherker & Sébastien Landry & Rachel K. Szilard & Meagan M. Munro & Andrea McEwan & Théo Goullet de Rugy & Zhen-Yuan Lin & Traver Hart & Jason Moffat & Anne-Claude Gingras & Alberto Martin & Haico Attikum & Jos Jonkers & Christopher J. Lord & Sven Rottenberg & Daniel Durocher - 122-127 53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
by Hind Ghezraoui & Catarina Oliveira & Jordan R. Becker & Kirstin Bilham & Daniela Moralli & Consuelo Anzilotti & Roman Fischer & Mukta Deobagkar-Lele & Maria Sanchiz-Calvo & Elena Fueyo-Marcos & Sarah Bonham & Benedikt M. Kessler & Sven Rottenberg & Richard J. Cornall & Catherine M. Green & J. Ross Chapman - 128-132 Structures of human Patched and its complex with native palmitoylated sonic hedgehog
by Xiaofeng Qi & Philip Schmiege & Elias Coutavas & Jiawei Wang & Xiaochun Li - 133-134 Why it is not a ‘failure’ to leave academia
by Philipp Kruger - 136-136 The tail of Danny Whiskers
by Fawaz Al-Matrouk
July 2018, Volume 559, Issue 7715
- 1-1 Alzheimer’s disease
by Richard Hodson - 2-3 An age-old story of dementia
by Liam Drew - 4-7 The amyloid hypothesis on trial
by Simon Makin - 8-9 Drawing on the brain’s resilience to fight Alzheimer’s disease
by Lauren Gravitz - 10-12 Alzheimer’s disease is getting easier to spot
by Elie Dolgin - 11-11 Author Correction: EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma
by Aparna Gorthi & July Carolina Romero & Eva Loranc & Lin Cao & Liesl A. Lawrence & Elicia Goodale & Amanda Balboni Iniguez & Xavier Bernard & V. Pragathi Masamsetti & Sydney Roston & Elizabeth R. Lawlor & Jeffrey A. Toretsky & Kimberly Stegmaier & Stephen L. Lessnick & Yidong Chen & Alexander J. R. Bishop - 13-13 Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation
by Dimitre R. Simeonov & Benjamin G. Gowen & Mandy Boontanrart & Theodore L. Roth & John D. Gagnon & Maxwell R. Mumbach & Ansuman T. Satpathy & Youjin Lee & Nicolas L. Bray & Alice Y. Chan & Dmytro S. Lituiev & Michelle L. Nguyen & Rachel E. Gate & Meena Subramaniam & Zhongmei Li & Jonathan M. Woo & Therese Mitros & Graham J. Ray & Gemma L. Curie & Nicki Naddaf & Julia S. Chu & Hong Ma & Eric Boyer & Frederic Gool & Hailiang Huang & Ruize Liu & Victoria R. Tobin & Kathrin Schumann & Mark J. Daly & Kyle K. Farh & K. Mark Ansel & Chun J. Ye & William J. Greenleaf & Mark S. Anderson & Jeffrey A. Bluestone & Howard Y. Chang & Jacob E. Corn & Alexander Marson - 13-15 The search for better animal models of Alzheimer’s disease
by Anthony King - 16-17 Ways to stop the spread of Alzheimer’s disease
by Moheb Costandi - 18-20 How the evidence stacks up for preventing Alzheimer’s disease
by Emily Sohn - 445-445 Preprints could promote confusion and distortion
by Tom Sheldon - 451-452 Ecologists try to speed up evolution to save Australian marsupial from toxic toads
by April Reese - 452-453 Death-defying NASA mission will make humanity’s closest approach to the Sun
by Alexandra Witze - 453-454 Philippines sweetens deal for scientists who return home
by Andrew Silver - 454-455 Dutch publishing giant cuts off researchers in Germany and Sweden
by Holly Else - 455-456 Big Bang telescope finale marks end of an era in cosmology
by Davide Castelvecchi - 458-465 How to defuse malaria’s ticking time bomb
by Amy Maxmen - 467-470 Ten years left to redesign lithium-ion batteries
by Kostiantyn Turcheniuk & Dmitry Bondarev & Vinod Singhal & Gleb Yushin - 470-472 Pet genomics medicine runs wild
by Lisa Moses & Steve Niemi & Elinor Karlsson - 473-475 Ancient dreams of intelligent machines: 3,000 years of robots
by Stephen Cave & Kanta Dihal - 475-475 The souls of deserts, a gathering of visionary biologists, and an inside view on exoplanets: Books in brief
by Barbara Kiser - 477-477 Modelling the trajectory of disease outbreaks works
by Caitlin M. Rivers & Samuel V. Scarpino - 477-477 From literature search to vaccine candidate without a lab
by Reza Forough & Mohammad Mian & Anthony Klobas & Jeffrey Talada - 477-477 The United States will lose money if it charges for Earth observation data
by Barbara J. Ryan - 477-477 Don’t ignore health-care impacts of Internet shutdowns
by Okwen Mbah & Miriam Nkangu & Zak Rogoff - 480-481 An early hominin arrival in Asia
by John Kappelman - 481-482 Quantum optics without photons
by Alejandro González Tudela & J. Ignacio Cirac - 482-484 Viruses cooperate to defeat bacteria
by Aude Bernheim & Rotem Sorek - 484-485 Histidine metabolism boosts cancer therapy
by Christian Frezza - 485-487 Neural circuit evolved to process pheromone differently in two species of fruit fly
by Nicolas Gompel & Benjamin Prud’homme - 487-488 Ancient ice sheet had a growth spurt
by Pippa Whitehouse - 489-489 Tropics
by Anna Armstrong & I-han Chou & Juliane Mossinger & Clare Thomas & Christina Tobin Kårlström & Michael White - 490-497 Challenges and opportunities in controlling mosquito-borne infections
by Neil M. Ferguson - 498-506 Challenges and recent progress in drug discovery for tropical diseases
by Manu Rycker & Beatriz Baragaña & Suzanne L. Duce & Ian H. Gilbert - 507-516 Acting on non-communicable diseases in low- and middle-income tropical countries
by Majid Ezzati & Jonathan Pearson-Stuttard & James E. Bennett & Colin D. Mathers - 517-526 The future of hyperdiverse tropical ecosystems
by Jos Barlow & Filipe França & Toby A. Gardner & Christina C. Hicks & Gareth D. Lennox & Erika Berenguer & Leandro Castello & Evan P. Economo & Joice Ferreira & Benoit Guénard & Cecília Gontijo Leal & Victoria Isaac & Alexander C. Lees & Catherine L. Parr & Shaun K. Wilson & Paul J. Young & Nicholas A. J. Graham - 527-534 The tropical forest carbon cycle and climate change
by Edward T. A. Mitchard - 535-545 El Niño–Southern Oscillation complexity
by Axel Timmermann & Soon-Il An & Jong-Seong Kug & Fei-Fei Jin & Wenju Cai & Antonietta Capotondi & Kim M. Cobb & Matthieu Lengaigne & Michael J. McPhaden & Malte F. Stuecker & Karl Stein & Andrew T. Wittenberg & Kyung-Sook Yun & Tobias Bayr & Han-Ching Chen & Yoshimitsu Chikamoto & Boris Dewitte & Dietmar Dommenget & Pamela Grothe & Eric Guilyardi & Yoo-Geun Ham & Michiya Hayashi & Sarah Ineson & Daehyun Kang & Sunyong Kim & WonMoo Kim & June-Yi Lee & Tim Li & Jing-Jia Luo & Shayne McGregor & Yann Planton & Scott Power & Harun Rashid & Hong-Li Ren & Agus Santoso & Ken Takahashi & Alexander Todd & Guomin Wang & Guojian Wang & Ruihuang Xie & Woo-Hyun Yang & Sang-Wook Yeh & Jinho Yoon & Elke Zeller & Xuebin Zhang - 547-555 Machine learning for molecular and materials science
by Keith T. Butler & Daniel W. Davies & Hugh Cartwright & Olexandr Isayev & Aron Walsh - 556-563 Niobium tungsten oxides for high-rate lithium-ion energy storage
by Kent J. Griffith & Kamila M. Wiaderek & Giannantonio Cibin & Lauren E. Marbella & Clare P. Grey - 564-569 Evolution of a central neural circuit underlies Drosophila mate preferences
by Laura F. Seeholzer & Max Seppo & David L. Stern & Vanessa Ruta - 570-574 Cryo-EM structure of a fungal mitochondrial calcium uniporter
by Nam X. Nguyen & Jean-Paul Armache & Changkeun Lee & Yi Yang & Weizhong Zeng & Vamsi K. Mootha & Yifan Cheng & Xiao-chen Bai & Youxing Jiang - 575-579 X-ray and cryo-EM structures of the mitochondrial calcium uniporter
by Chao Fan & Minrui Fan & Benjamin J. Orlando & Nathan M. Fastman & Jinru Zhang & Yan Xu & Melissa G. Chambers & Xiaofang Xu & Kay Perry & Maofu Liao & Liang Feng - 580-584 Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
by Rozbeh Baradaran & Chongyuan Wang & Andrew Francis Siliciano & Stephen Barstow Long - 585-588 The formation of solar-neighbourhood stars in two generations separated by 5 billion years
by Masafumi Noguchi - 589-592 Spontaneous emission of matter waves from a tunable open quantum system
by Ludwig Krinner & Michael Stewart & Arturo Pazmiño & Joonhyuk Kwon & Dominik Schneble - 593-598 Complex silica composite nanomaterials templated with DNA origami
by Xiaoguo Liu & Fei Zhang & Xinxin Jing & Muchen Pan & Pi Liu & Wei Li & Bowen Zhu & Jiang Li & Hong Chen & Lihua Wang & Jianping Lin & Yan Liu & Dongyuan Zhao & Hao Yan & Chunhai Fan - 599-602 Atmosphere–soil carbon transfer as a function of soil depth
by Jérôme Balesdent & Isabelle Basile-Doelsch & Joël Chadoeuf & Sophie Cornu & Delphine Derrien & Zuzana Fekiacova & Christine Hatté - 603-607 Rapid glaciation and a two-step sea level plunge into the Last Glacial Maximum
by Yusuke Yokoyama & Tezer M. Esat & William G. Thompson & Alexander L. Thomas & Jody M. Webster & Yosuke Miyairi & Chikako Sawada & Takahiro Aze & Hiroyuki Matsuzaki & Jun’ichi Okuno & Stewart Fallon & Juan-Carlos Braga & Marc Humblet & Yasufumi Iryu & Donald C. Potts & Kazuhiko Fujita & Atsushi Suzuki & Hironobu Kan - 608-612 Hominin occupation of the Chinese Loess Plateau since about 2.1 million years ago
by Zhaoyu Zhu & Robin Dennell & Weiwen Huang & Yi Wu & Shifan Qiu & Shixia Yang & Zhiguo Rao & Yamei Hou & Jiubing Xie & Jiangwei Han & Tingping Ouyang - 613-616 Triple oxygen isotope evidence for limited mid-Proterozoic primary productivity
by Peter W. Crockford & Justin A. Hayles & Huiming Bao & Noah J. Planavsky & Andrey Bekker & Philip W. Fralick & Galen P. Halverson & Thi Hao Bui & Yongbo Peng & Boswell A. Wing - 617-621 The outer membrane is an essential load-bearing element in Gram-negative bacteria
by Enrique R. Rojas & Gabriel Billings & Pascal D. Odermatt & George K. Auer & Lillian Zhu & Amanda Miguel & Fred Chang & Douglas B. Weibel & Julie A. Theriot & Kerwyn Casey Huang - 622-626 Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells
by Chamutal Bornstein & Shir Nevo & Amir Giladi & Noam Kadouri & Marie Pouzolles & François Gerbe & Eyal David & Alice Machado & Anna Chuprin & Beáta Tóth & Ori Goldberg & Shalev Itzkovitz & Naomi Taylor & Philippe Jay & Valérie S. Zimmermann & Jakub Abramson & Ido Amit - 627-631 Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development
by Corey N. Miller & Irina Proekt & Jakob Moltke & Kristen L. Wells & Aparna R. Rajpurkar & Haiguang Wang & Kristin Rattay & Imran S. Khan & Todd C. Metzger & Joshua L. Pollack & Adam C. Fries & Wint W. Lwin & Eric J. Wigton & Audrey V. Parent & Bruno Kyewski & David J. Erle & Kristin A. Hogquist & Lars M. Steinmetz & Richard M. Locksley & Mark S. Anderson - 632-636 Histidine catabolism is a major determinant of methotrexate sensitivity
by Naama Kanarek & Heather R. Keys & Jason R. Cantor & Caroline A. Lewis & Sze Ham Chan & Tenzin Kunchok & Monther Abu-Remaileh & Elizaveta Freinkman & Lawrence D. Schweitzer & David M. Sabatini - 637-641 Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer
by Di Wu & Di Hu & Hao Chen & Guoming Shi & Irfete S. Fetahu & Feizhen Wu & Kimberlie Rabidou & Rui Fang & Li Tan & Shuyun Xu & Hang Liu & Christian Argueta & Lei Zhang & Fei Mao & Guoquan Yan & Jiajia Chen & Zhaoru Dong & Ruitu Lv & Yufei Xu & Mei Wang & Yong Ye & Shike Zhang & Danielle Duquette & Songmei Geng & Clark Yin & Christine Guo Lian & George F. Murphy & Gail K. Adler & Rajesh Garg & Lydia Lynch & Pengyuan Yang & Yiming Li & Fei Lan & Jia Fan & Yang Shi & Yujiang Geno Shi - 643-645 The hackers teaching old DNA sequencers new tricks
by Jeffrey M. Perkel - 647-649 How to deliver sound science in resource-poor regions
by Josie Glausiusz - 652-652 Surrogate
by Griffin Ayaz Tyree
July 2018, Volume 559, Issue 7714
- 8-8 Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
by Nicole M. Gaudelli & Alexis C. Komor & Holly A. Rees & Michael S. Packer & Ahmed H. Badran & David I. Bryson & David R. Liu - 9-9 Author Correction: Diffusible repression of cytokinin signalling produces endodermal symmetry and passage cells
by Tonni Grube Andersen & Sadaf Naseer & Robertas Ursache & Brecht Wybouw & Wouter Smet & Bert Rybel & Joop E. M. Vermeer & Niko Geldner - 10-10 Author Correction: The landscape of genomic alterations across childhood cancers
by Susanne N. Gröbner & Barbara C. Worst & Joachim Weischenfeldt & Ivo Buchhalter & Kortine Kleinheinz & Vasilisa A. Rudneva & Pascal D. Johann & Gnana Prakash Balasubramanian & Maia Segura-Wang & Sebastian Brabetz & Sebastian Bender & Barbara Hutter & Dominik Sturm & Elke Pfaff & Daniel Hübschmann & Gideon Zipprich & Michael Heinold & Jürgen Eils & Christian Lawerenz & Serap Erkek & Sander Lambo & Sebastian Waszak & Claudia Blattmann & Arndt Borkhardt & Michaela Kuhlen & Angelika Eggert & Simone Fulda & Manfred Gessler & Jenny Wegert & Roland Kappler & Daniel Baumhoer & Stefan Burdach & Renate Kirschner-Schwabe & Udo Kontny & Andreas E. Kulozik & Dietmar Lohmann & Simone Hettmer & Cornelia Eckert & Stefan Bielack & Michaela Nathrath & Charlotte Niemeyer & Günther H. Richter & Johannes Schulte & Reiner Siebert & Frank Westermann & Jan J. Molenaar & Gilles Vassal & Hendrik Witt & Birgit Burkhardt & Christian P. Kratz & Olaf Witt & Cornelis M. Tilburg & Christof M. Kramm & Gudrun Fleischhack & Uta Dirksen & Stefan Rutkowski & Michael Frühwald & Katja Hoff & Stephan Wolf & Thomas Klingebiel & Ewa Koscielniak & Pablo Landgraf & Jan Koster & Adam C. Resnick & Jinghui Zhang & Yanling Liu & Xin Zhou & Angela J. Waanders & Danny A. Zwijnenburg & Pichai Raman & Benedikt Brors & Ursula D. Weber & Paul A. Northcott & Kristian W. Pajtler & Marcel Kool & Rosario M. Piro & Jan O. Korbel & Matthias Schlesner & Roland Eils & David T. W. Jones & Peter Lichter & Lukas Chavez & Marc Zapatka & Stefan M. Pfister - 303-303 Why I testified in the Argentina abortion debate
by Alberto Kornblihtt - 309-310 Single subatomic particle illuminates mysterious origins of cosmic rays
by Davide Castelvecchi - 310-311 China expands surveillance of sewage to police illegal drug use
by David Cyranoski - 311-312 Science journals end open-access trial with Gates Foundation
by Richard Van Noorden - 312-313 Jupiter has 10 more moons we didn't know about — and they're weird
by Alexandra Witze - 313-314 Gene therapy in mouse fetuses treats deadly disease
by Heidi Ledford - 316-319 Science under siege: behind the scenes at Trump’s troubled environment agency
by Jeff Tollefson - 321-324 Beat protectionism and emissions at a stroke
by Michael A. Mehling & Harro van Asselt & Kasturi Das & Susanne Droege - 324-326 AI can be sexist and racist — it’s time to make it fair
by James Zou & Londa Schiebinger - 328-330 Summer reads: Darwin’s dilemma on sexual selection, ecology versus empire, and the dark side of the greater good
by Andrew Jaffe & Fatimah Jackson & Elizabeth Yale & Adam Rome & Jennifer Rohn & Tim Radford & Alex Haslam & Diane Coyle - 331-331 Evaluation woes: Metrics can help beat bias
by Li Tang & Guangyuan Hu - 331-331 Evaluation woes: define metrics from the off
by Paola Zaratin & Marco Salvetti - 331-331 Learn from industry to build a healthy lab
by Z. Hugh Fan - 331-331 Iran’s scientists uncrushed by decades of sanctions
by Shahin Akhondzadeh - 331-331 Evaluation woes: professors should have fought harder
by Andrew Beattie - 334-335 A record-breaking microscope
by John Rodenburg - 335-336 Coronary artery development, one cell at a time
by Arndt F. Siekmann - 336-338 High-quality genomes reveal new differences between the great apes
by Aylwyn Scally - 338-339 Resistance to prostate-cancer treatment is driven by immune cells
by Matthew D. Galsky - 340-341 Sluggish Atlantic circulation could cause global temperatures to surge
by Gerard D. McCarthy & Peter W. Thorne - 341-342 Speciation far from the madding crowd
by Arne O. Mooers & Dan A. Greenberg - 343-349 Electron ptychography of 2D materials to deep sub-ångström resolution
by Yi Jiang & Zhen Chen & Yimo Han & Pratiti Deb & Hui Gao & Saien Xie & Prafull Purohit & Mark W. Tate & Jiwoong Park & Sol M. Gruner & Veit Elser & David A. Muller - 350-355 Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations
by Po-Ru Loh & Giulio Genovese & Robert E. Handsaker & Hilary K. Finucane & Yakir A. Reshef & Pier Francesco Palamara & Brenda M. Birmann & Michael E. Talkowski & Samuel F. Bakhoum & Steven A. McCarroll & Alkes L. Price - 356-362 Single-cell analysis of early progenitor cells that build coronary arteries
by Tianying Su & Geoff Stanley & Rahul Sinha & Gaetano D’Amato & Soumya Das & Siyeon Rhee & Andrew H. Chang & Aruna Poduri & Brian Raftrey & Thanh Theresa Dinh & Walter A. Roper & Guang Li & Kelsey E. Quinn & Kathleen M. Caron & Sean Wu & Lucile Miquerol & Eugene C. Butcher & Irving Weissman & Stephen Quake & Kristy Red-Horse - 363-369 IL-23 secreted by myeloid cells drives castration-resistant prostate cancer
by Arianna Calcinotto & Clarissa Spataro & Elena Zagato & Diletta Di Mitri & Veronica Gil & Mateus Crespo & Gaston De Bernardis & Marco Losa & Michela Mirenda & Emiliano Pasquini & Andrea Rinaldi & Semini Sumanasuriya & Maryou B. Lambros & Antje Neeb & Roberta Lucianò & Carlo A. Bravi & Daniel Nava-Rodrigues & David Dolling & Tommaso Prayer-Galetti & Ana Ferreira & Alberto Briganti & Antonio Esposito & Simon Barry & Wei Yuan & Adam Sharp & Johann de Bono & Andrea Alimonti - 370-376 Scaling up molecular pattern recognition with DNA-based winner-take-all neural networks
by Kevin M. Cherry & Lulu Qian - 377-381 Controlling an organic synthesis robot with machine learning to search for new reactivity
by Jarosław M. Granda & Liva Donina & Vincenza Dragone & De-Liang Long & Leroy Cronin - 382-386 Synchronous tropical and polar temperature evolution in the Eocene
by Marlow J. Cramwinckel & Matthew Huber & Ilja J. Kocken & Claudia Agnini & Peter K. Bijl & Steven M. Bohaty & Joost Frieling & Aaron Goldner & Frederik J. Hilgen & Elizabeth L. Kip & Francien Peterse & Robin Ploeg & Ursula Röhl & Stefan Schouten & Appy Sluijs - 387-391 Global surface warming enhanced by weak Atlantic overturning circulation
by Xianyao Chen & Ka-Kit Tung - 392-395 An inverse latitudinal gradient in speciation rate for marine fishes
by Daniel L. Rabosky & Jonathan Chang & Pascal O. Title & Peter F. Cowman & Lauren Sallan & Matt Friedman & Kristin Kaschner & Cristina Garilao & Thomas J. Near & Marta Coll & Michael E. Alfaro - 396-399 Hot streaks in artistic, cultural, and scientific careers
by Lu Liu & Yang Wang & Roberta Sinatra & C. Lee Giles & Chaoming Song & Dashun Wang - 400-404 Prediction of acute myeloid leukaemia risk in healthy individuals
by Sagi Abelson & Grace Collord & Stanley W. K. Ng & Omer Weissbrod & Netta Mendelson Cohen & Elisabeth Niemeyer & Noam Barda & Philip C. Zuzarte & Lawrence Heisler & Yogi Sundaravadanam & Robert Luben & Shabina Hayat & Ting Ting Wang & Zhen Zhao & Iulia Cirlan & Trevor J. Pugh & David Soave & Karen Ng & Calli Latimer & Claire Hardy & Keiran Raine & David Jones & Diana Hoult & Abigail Britten & John D. McPherson & Mattias Johansson & Faridah Mbabaali & Jenna Eagles & Jessica K. Miller & Danielle Pasternack & Lee Timms & Paul Krzyzanowski & Philip Awadalla & Rui Costa & Eran Segal & Scott V. Bratman & Philip Beer & Sam Behjati & Inigo Martincorena & Jean C. Y. Wang & Kristian M. Bowles & J. Ramón Quirós & Anna Karakatsani & Carlo Vecchia & Antonia Trichopoulou & Elena Salamanca-Fernández & José M. Huerta & Aurelio Barricarte & Ruth C. Travis & Rosario Tumino & Giovanna Masala & Heiner Boeing & Salvatore Panico & Rudolf Kaaks & Alwin Krämer & Sabina Sieri & Elio Riboli & Paolo Vineis & Matthieu Foll & James McKay & Silvia Polidoro & Núria Sala & Kay-Tee Khaw & Roel Vermeulen & Peter J. Campbell & Elli Papaemmanuil & Mark D. Minden & Amos Tanay & Ran D. Balicer & Nicholas J. Wareham & Moritz Gerstung & John E. Dick & Paul Brennan & George S. Vassiliou & Liran I. Shlush - 405-409 Reprogramming human T cell function and specificity with non-viral genome targeting
by Theodore L. Roth & Cristina Puig-Saus & Ruby Yu & Eric Shifrut & Julia Carnevale & P. Jonathan Li & Joseph Hiatt & Justin Saco & Paige Krystofinski & Han Li & Victoria Tobin & David N. Nguyen & Michael R. Lee & Amy L. Putnam & Andrea L. Ferris & Jeff W. Chen & Jean-Nicolas Schickel & Laurence Pellerin & David Carmody & Gorka Alkorta-Aranburu & Daniela del Gaudio & Hiroyuki Matsumoto & Montse Morell & Ying Mao & Min Cho & Rolen M. Quadros & Channabasavaiah B. Gurumurthy & Baz Smith & Michael Haugwitz & Stephen H. Hughes & Jonathan S. Weissman & Kathrin Schumann & Jonathan H. Esensten & Andrew P. May & Alan Ashworth & Gary M. Kupfer & Siri Atma W. Greeley & Rosa Bacchetta & Eric Meffre & Maria Grazia Roncarolo & Neil Romberg & Kevan C. Herold & Antoni Ribas & Manuel D. Leonetti & Alexander Marson - 410-414 Mechanism of parkin activation by PINK1
by Christina Gladkova & Sarah L. Maslen & J. Mark Skehel & David Komander - 415-418 Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action
by Yan Yan & Qikun Liu & Xin Zang & Shuguang Yuan & Undramaa Bat-Erdene & Calvin Nguyen & Jianhua Gan & Jiahai Zhou & Steven E. Jacobsen & Yi Tang - 419-422 Prespliceosome structure provides insights into spliceosome assembly and regulation
by Clemens Plaschka & Pei-Chun Lin & Clément Charenton & Kiyoshi Nagai - 423-427 PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
by Hsin-Yung Yen & Kin Kuan Hoi & Idlir Liko & George Hedger & Michael R. Horrell & Wanling Song & Di Wu & Philipp Heine & Tony Warne & Yang Lee & Byron Carpenter & Andreas Plückthun & Christopher G. Tate & Mark S. P. Sansom & Carol V. Robinson - 429-431 How retirement can give your career a new lease of life
by Amber Dance - 431-431 Why organizing a scientific conference can produce huge benefits
by Francesco Sciortino - 434-434 Papa Bear
by Kurt Pankau
July 2018, Volume 559, Issue 7713
- 4-4 Publisher Correction: Pervasive phosphorus limitation of tree species but not communities in tropical forests
by Benjamin L. Turner & Tania Brenes-Arguedas & Richard Condit - 5-5 Author Correction: A series of energetic metal pentazolate hydrates
by Yuangang Xu & Qian Wang & Cheng Shen & Qiuhan Lin & Pengcheng Wang & Ming Lu - 6-6 Author Correction: Roads towards fault-tolerant universal quantum computation
by Earl T. Campbell & Barbara M. Terhal & Christophe Vuillot - 7-7 Publisher Correction: A TRP channel trio mediates acute noxious heat sensing
by Ine Vandewauw & Katrien Clercq & Marie Mulier & Katharina Held & Silvia Pinto & Nele Ranst & Andrei Segal & Thierry Voet & Rudi Vennekens & Katharina Zimmermann & Joris Vriens & Thomas Voets - 153-153 Lab heads should learn to talk about racism
by Devang Mehta - 159-160 Max Planck astrophysicist at centre of bullying allegations speaks up
by Alison Abbott - 160-161 Foreign-researcher figures stress need for immigration reform before Brexit
by Elizabeth Gibney - 162-162 Coming soon to a lab near you? Genetically modified cannabis
by Amy Maxmen - 163-163 Software beats animal tests at predicting toxicity of chemicals
by Richard Van Noorden - 164-164 Controversial CRISPR ‘gene drives’ tested in mammals for the first time
by Ewen Callaway - 165-168 100 bats and a long, dark tunnel: one neuroscientist’s quest to unlock the secrets of 3D navigation
by Alison Abbott - 169-173 Grand challenges in humanitarian aid
by Abdallah S. Daar & Trillium Chang & Angela Salomon & Peter A. Singer - 174-176 Cape Town’s drought: don’t blame climate change
by Mike Muller - 178-179 The imperial roots of climate science
by Mott Greene - 179-179 A guidebook to cancer, slavery to stupid machines, and the buzz about bees: Books in brief
by Barbara Kiser - 180-180 The Flint water crisis: how citizen scientists exposed poisonous politics
by Mark Peplow - 181-181 EPA is open to scrutiny
by Charles Herrick - 181-181 Justification for the EPA’s transparency rule
by Peter Wood - 181-181 Local diagnostics kits for Africa being developed in Ghana
by Aniweh Yaw & Kanyong Prosper & Francis Krampa & Gordon A. Awandare - 181-181 Two centuries since discovery of dawn-of-life molecule
by Willem H. Koppenol & Helmut Sies - 181-181 Now India is electrified, bring on the renewables
by Shekhar Chandra & Lawrence E. Susskind - 184-185 Self-organizing multicellular structures designed using synthetic biology
by Jesse Tordoff & Ron Weiss - 185-186 A fresh take on ancient climate change in the North Pacific
by Kaustubh Thirumalai - 186-187 Superfast DNA replication causes damage in cancer cells
by Annabel Quinet & Alessandro Vindigni - 188-189 Estimate suggests many infant deaths in sub-Saharan Africa attributable to air pollution
by Lance A. Waller - 189-190 The heat is on for Majorana fermions
by Kirill Shtengel - 190-191 How rats wreak havoc on coral reefs
by Nancy Knowlton - 193-204 China’s response to a national land-system sustainability emergency
by Brett A. Bryan & Lei Gao & Yanqiong Ye & Xiufeng Sun & Jeffery D. Connor & Neville D. Crossman & Mark Stafford-Smith & Jianguo Wu & Chunyang He & Deyong Yu & Zhifeng Liu & Ang Li & Qingxu Huang & Hai Ren & Xiangzheng Deng & Hua Zheng & Jianming Niu & Guodong Han & Xiangyang Hou - 205-210 Observation of half-integer thermal Hall conductance
by Mitali Banerjee & Moty Heiblum & Vladimir Umansky & Dima E. Feldman & Yuval Oreg & Ady Stern - 211-216 Kinase-controlled phase transition of membraneless organelles in mitosis
by Arpan Kumar Rai & Jia-Xuan Chen & Matthias Selbach & Lucas Pelkmans - 217-222 Structure of the origin recognition complex bound to DNA replication origin
by Ningning Li & Wai Hei Lam & Yuanliang Zhai & Jiaxuan Cheng & Erchao Cheng & Yongqian Zhao & Ning Gao & Bik-Kwoon Tye - 223-226 Non-gravitational acceleration in the trajectory of 1I/2017 U1 (‘Oumuamua)
by Marco Micheli & Davide Farnocchia & Karen J. Meech & Marc W. Buie & Olivier R. Hainaut & Dina Prialnik & Norbert Schörghofer & Harold A. Weaver & Paul W. Chodas & Jan T. Kleyna & Robert Weryk & Richard J. Wainscoat & Harald Ebeling & Jacqueline V. Keane & Kenneth C. Chambers & Detlef Koschny & Anastassios E. Petropoulos - 227-231 Majorana quantization and half-integer thermal quantum Hall effect in a Kitaev spin liquid
by Y. Kasahara & T. Ohnishi & Y. Mizukami & O. Tanaka & Sixiao Ma & K. Sugii & N. Kurita & H. Tanaka & J. Nasu & Y. Motome & T. Shibauchi & Y. Matsuda - 232-235 Metallic nanoparticle contacts for high-yield, ambient-stable molecular-monolayer devices
by Gabriel Puebla-Hellmann & Koushik Venkatesan & Marcel Mayor & Emanuel Lörtscher - 236-240 Electrically controlled water permeation through graphene oxide membranes
by K.-G. Zhou & K. S. Vasu & C. T. Cherian & M. Neek-Amal & J. C. Zhang & H. Ghorbanfekr-Kalashami & K. Huang & O. P. Marshall & V. G. Kravets & J. Abraham & Y. Su & A. N. Grigorenko & A. Pratt & A. K. Geim & F. M. Peeters & K. S. Novoselov & R. R. Nair - 241-245 North Pacific freshwater events linked to changes in glacial ocean circulation
by E. Maier & X. Zhang & A. Abelmann & R. Gersonde & S. Mulitza & M. Werner & M. Méheust & J. Ren & B. Chapligin & H. Meyer & R. Stein & R. Tiedemann & G. Lohmann - 246-249 Evolution of cooperation in stochastic games
by Christian Hilbe & Štěpán Šimsa & Krishnendu Chatterjee & Martin A. Nowak - 250-253 Seabirds enhance coral reef productivity and functioning in the absence of invasive rats
by Nicholas A. J. Graham & Shaun K. Wilson & Peter Carr & Andrew S. Hoey & Simon Jennings & M. Aaron MacNeil - 254-258 Robust relationship between air quality and infant mortality in Africa
by Sam Heft-Neal & Jennifer Burney & Eran Bendavid & Marshall Burke - 259-263 Species-specific activity of antibacterial drug combinations
by Ana Rita Brochado & Anja Telzerow & Jacob Bobonis & Manuel Banzhaf & André Mateus & Joel Selkrig & Emily Huth & Stefan Bassler & Jordi Zamarreño Beas & Matylda Zietek & Natalie Ng & Sunniva Foerster & Benjamin Ezraty & Béatrice Py & Frédéric Barras & Mikhail M. Savitski & Peer Bork & Stephan Göttig & Athanasios Typas - 264-268 The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells
by Henrique Borges da Silva & Lalit K. Beura & Haiguang Wang & Eric A. Hanse & Reshma Gore & Milcah C. Scott & Daniel A. Walsh & Katharine E. Block & Raissa Fonseca & Yan Yan & Keli L. Hippen & Bruce R. Blazar & David Masopust & Ameeta Kelekar & Lucy Vulchanova & Kristin A. Hogquist & Stephen C. Jameson - 269-273 Targeting STING with covalent small-molecule inhibitors
by Simone M. Haag & Muhammet F. Gulen & Luc Reymond & Antoine Gibelin & Laurence Abrami & Alexiane Decout & Michael Heymann & F. Gisou van der Goot & Gerardo Turcatti & Rayk Behrendt & Andrea Ablasser - 274-278 Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
by Claudio Alfieri & Leifu Chang & David Barford - 279-284 High speed of fork progression induces DNA replication stress and genomic instability
by Apolinar Maya-Mendoza & Pavel Moudry & Joanna Maria Merchut-Maya & MyungHee Lee & Robert Strauss & Jiri Bartek - 285-289 CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
by Michal Zimmermann & Olga Murina & Martin A. M. Reijns & Angelo Agathanggelou & Rachel Challis & Žygimantė Tarnauskaitė & Morwenna Muir & Adeline Fluteau & Michael Aregger & Andrea McEwan & Wei Yuan & Matthew Clarke & Maryou B. Lambros & Shankara Paneesha & Paul Moss & Megha Chandrashekhar & Stephane Angers & Jason Moffat & Valerie G. Brunton & Traver Hart & Johann Bono & Tatjana Stankovic & Andrew P. Jackson & Daniel Durocher - 291-293 How to start a lab when funds are tight
by Elie Dolgin - 296-296 Your face
by Grace Tang
July 2018, Volume 559, Issue 7712
- 1-1 Publisher Correction: Adolescence and the next generation
by George C. Patton & Craig A. Olsson & Vegard Skirbekk & Richard Saffery & Mary E. Wlodek & Peter S. Azzopardi & Marcin Stonawski & Bruce Rasmussen & Elizabeth Spry & Kate Francis & Zulfiqar A. Bhutta & Nicholas J. Kassebaum & Ali H. Mokdad & Christopher J. L. Murray & Andrew M. Prentice & Nicola Reavley & Peter Sheehan & Kim Sweeny & Russell M. Viner & Susan M. Sawyer - 2-2 Author Correction: The axolotl genome and the evolution of key tissue formation regulators
by Sergej Nowoshilow & Siegfried Schloissnig & Ji-Feng Fei & Andreas Dahl & Andy W. C. Pang & Martin Pippel & Sylke Winkler & Alex R. Hastie & George Young & Juliana G. Roscito & Francisco Falcon & Dunja Knapp & Sean Powell & Alfredo Cruz & Han Cao & Bianca Habermann & Michael Hiller & Elly M. Tanaka & Eugene W. Myers - 3-3 Addendum: Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols
by Shi-Liang Shi & Zackary L. Wong & Stephen L. Buchwald - 6-6 A welcome from the new Nature editor
by Magdalena Skipper - 7-7 Advance the ecosystem approach in cities
by Xuemei Bai - 13-14 Gigantic study of Chinese babies yields slew of health data
by David Cyranoski - 14-15 There’s no limit to longevity, says study that revives human lifespan debate
by Elie Dolgin - 15-16 Cyprus asserts itself as regional hub for climate-change research
by Anita Makri - 16-17 Delays mount for NASA’s $8-billion Hubble successor
by Alexandra Witze - 17-18 Europe’s biggest research fund cracks down on ‘ethics dumping’
by Linda Nordling - 19-22 The labs growing human embryos for longer than ever before
by Helen Shen - 23-26 A better measure of research from the global south
by Jean Lebel & Robert McLean - 27-28 LGBTQ scientists are still left out
by Jon Freeman - 29-30 UNESCO’s troubled drive for peace through science and culture
by Andrew Robinson - 31-31 The backbone begins: a spine-tingling story
by Chris Lowe - 32-32 Italy is squeezing out wet biology research
by Davide Zannoni - 32-32 Evaluation woes: we’re on it, responds DORA
by Anna Hatch & Stephen Curry - 32-32 University came to the rescue of accused researcher
by Roberto Caminiti - 32-32 Personalized medicine should not be restricted to the wealthy
by Colum P. Dunne & Suzanne S. Dunne - 34-35 Doubt cast on how the pace of global glacial erosion responds to climate cooling
by Eric Kirby - 35-37 Actin proteins assemble to protect the genome
by Vassilis Roukos - 37-38 Key receptor involved in neuronal signalling visualized
by Erwin Sigel - 38-40 A molecular signature for social isolation identified in the brain
by Noga Zilkha & Tali Kimchi - 40-41 General relativity verified by a triple-star system
by Clifford M. Will - 41-42 Unexpected cell population gives fat a brake
by David A. Guertin - 42-43 Taking bioengineered heart valves from faulty to functional
by Craig A. Simmons