Content
November 2015, Volume 527, Issue 7579
- 218-219 The problem with platinum
by David Holmes - 411-411 A ‘perfect’ agreement in Paris is not essential
by Johan Rockström - 413-413 Text-mining block prompts online response
by Mollie Bloudoff-Indelicato - 417-418 Salmon approval heralds rethink of transgenic animals
by Heidi Ledford - 418-419 Climate optimism builds ahead of Paris talks
by Jeff Tollefson - 419-420 Green Climate Fund faces slew of criticism
by Sanjay Kumar - 420-421 Brazilian courts tussle over unproven cancer treatment
by Heidi Ledford - 421-422 Leap-second decision delayed by eight years
by Elizabeth Gibney - 422-423 'Digital chimp' trove preserves brains of retired apes
by Sara Reardon - 427-435 The fragile framework
by Richard Monastersky & Nick Sousanis - 436-438 Is the 2 °C world a fantasy?
by Jeff Tollefson - 439-441 Global climate agreement: After the talks
by David G. Victor & James P. Leape - 441-442 Materials science: Share corrosion data
by Xiaogang Li & Dawei Zhang & Zhiyong Liu & Zhong Li & Cuiwei Du & Chaofang Dong - 443-445 Sustainability: The launch of Spaceship Earth
by Adam Rome - 445-445 Books in brief
by Barbara Kiser - 446-446 Climate change also creates expatriates
by Ralf Buckley - 446-446 Gene editing: Govern ability expectations
by Gregor Wolbring - 446-446 Lessons from EPA on tracking pollutants
by Bo Zhang & Wayne S. Davis - 446-446 Gene editing: Survey invites opinions
by Silvia Camporesi & Lara Marks - 446-446 Crowdfunding not fit for clinical trials
by Phaik Yeong Cheah - 446-446 Gene editing: Heed disability views
by Tom Shakespeare - 448-449 Acorn worms in a nutshell
by Casey W. Dunn - 449-451 A receptor for subtle temperature changes
by François Rouyer & Abhishek Chatterjee - 451-452 Super-resolution ultrasound
by Ben Cox & Paul Beard - 452-453 Transition loses its invasive edge
by Shyamala Maheswaran & Daniel A. Haber - 453-455 Hidden reservoirs
by Jonathan L. Heeney - 455-456 The Moon's tilt for gold
by Robin Canup - 456-457 Assassins of eyesight
by Andrew D. Huberman & Rana N. El-Danaf - 459-465 Hemichordate genomes and deuterostome origins
by Oleg Simakov & Takeshi Kawashima & Ferdinand Marlétaz & Jerry Jenkins & Ryo Koyanagi & Therese Mitros & Kanako Hisata & Jessen Bredeson & Eiichi Shoguchi & Fuki Gyoja & Jia-Xing Yue & Yi-Chih Chen & Robert M. Freeman & Akane Sasaki & Tomoe Hikosaka-Katayama & Atsuko Sato & Manabu Fujie & Kenneth W. Baughman & Judith Levine & Paul Gonzalez & Christopher Cameron & Jens H. Fritzenwanker & Ariel M. Pani & Hiroki Goto & Miyuki Kanda & Nana Arakaki & Shinichi Yamasaki & Jiaxin Qu & Andrew Cree & Yan Ding & Huyen H. Dinh & Shannon Dugan & Michael Holder & Shalini N. Jhangiani & Christie L. Kovar & Sandra L. Lee & Lora R. Lewis & Donna Morton & Lynne V. Nazareth & Geoffrey Okwuonu & Jireh Santibanez & Rui Chen & Stephen Richards & Donna M. Muzny & Andrew Gillis & Leonid Peshkin & Michael Wu & Tom Humphreys & Yi-Hsien Su & Nicholas H. Putnam & Jeremy Schmutz & Asao Fujiyama & Jr-Kai Yu & Kunifumi Tagawa & Kim C. Worley & Richard A. Gibbs & Marc W. Kirschner & Christopher J. Lowe & Noriyuki Satoh & Daniel S. Rokhsar & John Gerhart - 466-471 A perisinusoidal niche for extramedullary haematopoiesis in the spleen
by Christopher N. Inra & Bo O. Zhou & Melih Acar & Malea M. Murphy & James Richardson & Zhiyu Zhao & Sean J. Morrison - 472-476 Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
by Kari R. Fischer & Anna Durrans & Sharrell Lee & Jianting Sheng & Fuhai Li & Stephen T. C. Wong & Hyejin Choi & Tina El Rayes & Seongho Ryu & Juliane Troeger & Robert F. Schwabe & Linda T. Vahdat & Nasser K. Altorki & Vivek Mittal & Dingcheng Gao - 477-483 Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65
by Xi-Ping Huang & Joel Karpiak & Wesley K. Kroeze & Hu Zhu & Xin Chen & Sheryl S. Moy & Kara A. Saddoris & Viktoriya D. Nikolova & Martilias S. Farrell & Sheng Wang & Thomas J. Mangano & Deepak A. Deshpande & Alice Jiang & Raymond B. Penn & Jian Jin & Beverly H. Koller & Terry Kenakin & Brian K. Shoichet & Bryan L. Roth - 484-487 Extremely metal-poor stars from the cosmic dawn in the bulge of the Milky Way
by L. M. Howes & A. R. Casey & M. Asplund & S. C. Keller & D. Yong & D. M. Nataf & R. Poleski & K. Lind & C. Kobayashi & C. I. Owen & M. Ness & M. S. Bessell & G. S. Da Costa & B. P. Schmidt & P. Tisserand & A. Udalski & M. K. Szymański & I. Soszyński & G. Pietrzyński & K. Ulaczyk & Ł. Wyrzykowski & P. Pietrukowicz & J. Skowron & S. Kozłowski & P. Mróz - 488-491 Ubiquitous time variability of integrated stellar populations
by Charlie Conroy & Pieter G. van Dokkum & Jieun Choi - 492-494 Collisionless encounters and the origin of the lunar inclination
by Kaveh Pahlevan & Alessandro Morbidelli - 495-498 Type-II Weyl semimetals
by Alexey A. Soluyanov & Dominik Gresch & Zhijun Wang & QuanSheng Wu & Matthias Troyer & Xi Dai & B. Andrei Bernevig - 499-502 Ultrafast ultrasound localization microscopy for deep super-resolution vascular imaging
by Claudia Errico & Juliette Pierre & Sophie Pezet & Yann Desailly & Zsolt Lenkei & Olivier Couture & Mickael Tanter - 503-507 Extra adsorption and adsorbate superlattice formation in metal-organic frameworks
by Hae Sung Cho & Hexiang Deng & Keiichi Miyasaka & Zhiyue Dong & Minhyung Cho & Alexander V. Neimark & Jeung Ku Kang & Omar M. Yaghi & Osamu Terasaki - 508-511 Single-molecule sequencing of the desiccation-tolerant grass Oropetium thomaeum
by Robert VanBuren & Doug Bryant & Patrick P. Edger & Haibao Tang & Diane Burgess & Dinakar Challabathula & Kristi Spittle & Richard Hall & Jenny Gu & Eric Lyons & Michael Freeling & Dorothea Bartels & Boudewijn Ten Hallers & Alex Hastie & Todd P. Michael & Todd C. Mockler - 512-515 Sweet and bitter taste in the brain of awake behaving animals
by Yueqing Peng & Sarah Gillis-Smith & Hao Jin & Dimitri Tränkner & Nicholas J. P. Ryba & Charles S. Zuker - 516-520 Drosophila Ionotropic Receptor 25a mediates circadian clock resetting by temperature
by Chenghao Chen & Edgar Buhl & Min Xu & Vincent Croset & Johanna S. Rees & Kathryn S. Lilley & Richard Benton & James J. L. Hodge & Ralf Stanewsky - 521-524 Fungal pathogen uses sex pheromone receptor for chemotropic sensing of host plant signals
by David Turrà & Mennat El Ghalid & Federico Rossi & Antonio Di Pietro - 525-530 Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
by Xiaofeng Zheng & Julienne L. Carstens & Jiha Kim & Matthew Scheible & Judith Kaye & Hikaru Sugimoto & Chia-Chin Wu & Valerie S. LeBleu & Raghu Kalluri - 531-534 In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
by Xing Zhang & Ke Ding & Xuekui Yu & Winston Chang & Jingchen Sun & Z. Hong Zhou - 535-538 Foreign DNA capture during CRISPR–Cas adaptive immunity
by James K. Nuñez & Lucas B. Harrington & Philip J. Kranzusch & Alan N. Engelman & Jennifer A. Doudna - 539-543 RETRACTED ARTICLE: Endoperoxide formation by an α-ketoglutarate-dependent mononuclear non-haem iron enzyme
by Wupeng Yan & Heng Song & Fuhang Song & Yisong Guo & Cheng-Hsuan Wu & Ampon Sae Her & Yi Pu & Shu Wang & Nathchar Naowarojna & Andrew Weitz & Michael P. Hendrich & Catherine E. Costello & Lixin Zhang & Pinghua Liu & Yan Jessie Zhang - 544-544 Correction: Corrigendum: A basal ichthyosauriform with a short snout from the Lower Triassic of China
by Ryosuke Motani & Da-Yong Jiang & Guan-Bao Chen & Andrea Tintori & Olivier Rieppel & Cheng Ji & Jian-Dong Huang - 544-544 Retraction Note: Non-blinking semiconductor nanocrystals
by Xiaoyong Wang & Xiaofan Ren & Keith Kahen & Megan A. Hahn & Manju Rajeswaran & Sara Maccagnano-Zacher & John Silcox & George E. Cragg & Alexander L. Efros & Todd D. Krauss - 544-544 Correction: Corrigendum: Influence maximization in complex networks through optimal percolation
by Flaviano Morone & Hernán A. Makse - 545-551 Antibody anarchy: A call to order
by Monya Baker - 553-554 Mental health: The mindful way
by Sabine Louet - 554-554 Turning point: Jason Lunden
by Virginia Gewin - 556-556 Claimed
by S. J. Rosenstein
November 2015, Volume 527, Issue 7578
- 101-101 Breast cancer
by Chris Woolston - 102-103 A tumour through time
by Will Tauxe - 104-104 Perspective: The risks of overdiagnosis
by Alexandra Barratt - 105-107 Immunology: Another shot at cancer
by Charles Schmidt - 108-109 Genetics: Big hopes for big data
by Jill U. Adams - 110-112 Medicine: Eyes on the target
by Michael Eisenstein - 114-115 Molecular biology: Marked progress
by Hannah Hoag - 116-117 Genetics: Relative risk
by Moises Velasquez-Manoff - 118-119 Screening: Don't look now
by Emily Sohn - 120-120 Breast cancer: 4 big questions
by Chris Woolston - 150-150 Brain disorders across the lifespan
by Roger I. Glass - 151-154 Brain and other nervous system disorders across the lifespan — global challenges and opportunities
by Donald Silberberg & Nalini P. Anand & Kathleen Michels & Raj N. Kalaria - 155-160 Reducing neurodevelopmental disorders and disability through research and interventions
by Michael J. Boivin & Angelina M. Kakooza & Benjamin C. Warf & Leslie L. Davidson & Elena L. Grigorenko - 161-166 A focus on adolescence to reduce neurological, mental health and substance-use disability
by Leslie L. Davidson & Elena L. Grigorenko & Michael J. Boivin & Elizabeth Rapa & Alan Stein - 167-171 Nervous system disorders across the life course in resource-limited settings
by Gretchen L. Birbeck & Ana-Claire Meyer & Adesola Ogunniyi - 172-177 Global research challenges and opportunities for mental health and substance-use disorders
by Florence Baingana & Mustafa al'Absi & Anne E. Becker & Beverly Pringle - 178-186 Global research priorities for infections that affect the nervous system
by Chandy C. John & Hélène Carabin & Silvia M. Montano & Paul Bangirana & Joseph R. Zunt & Phillip K. Peterson - 187-192 A global perspective on the influence of environmental exposures on the nervous system
by Desire Tshala-Katumbay & Jean-Claude Mwanza & Diane S. Rohlman & Gladys Maestre & Reinaldo B. Oriá - 193-197 Global neurotrauma research challenges and opportunities
by Andrés M. Rubiano & Nancy Carney & Randall Chesnut & Juan Carlos Puyana - 198-206 Regional research priorities in brain and nervous system disorders
by Vijayalakshmi Ravindranath & Hoang-Minh Dang & Rodolfo G. Goya & Hader Mansour & Vishwajit L. Nimgaonkar & Vivienne Ann Russell & Yu Xin - 207-213 Building global capacity for brain and nervous system disorders research
by Linda B. Cottler & Joseph Zunt & Bahr Weiss & Ayeesha Kamran Kamal & Krishna Vaddiparti - 277-277 Time to cry out for academic freedom
by Colin Macilwain - 279-279 How to judge scientists’ strengths
by Dalmeet Singh Chawla - 283-284 Discovery of long-sought biological compass claimed
by David Cyranoski - 284-285 Freefall space cubes are test for gravitational wave spotter
by Elizabeth Gibney - 286-286 Wayward satellites repurposed to test general relativity
by Elizabeth Gibney - 286-287 Racial bias continues to haunt NIH grants
by Erika Check Hayden - 288-289 The exoplanet files
by Alexandra Witze - 290-293 The quantum source of space-time
by Ron Cowen - 295-297 Sustainability: Transfer project cannot meet China's water needs
by Jon Barnett & Sarah Rogers & Michael Webber & Brian Finlayson & Mark Wang - 298-300 History: Einstein was no lone genius
by Michel Janssen & Jürgen Renn - 302-303 Mathematics: Logic and Lewis Carroll
by Francine F. Abeles - 303-303 Books in brief
by Barbara Kiser - 305-305 Cannabis: monitor policy changes
by Lucas Wiessing - 305-305 Peat fires: consumers to help beat them out
by Lahiru S. Wijedasa & Mary Rose C. Posa & Gopalasamy R. Clements - 305-305 Cannabis: debated schizophrenia link
by Matthew Large & Marta Di Forti & Robin Murray - 305-305 Peat fires: emissions likely to worsen
by Susan G. Laurance & William F. Laurance - 305-305 Time for Russia to tap renewables
by Alexander Gorobets - 306-306 Richard Heck (1931–2015)
by Victor Snieckus - 308-309 Extra dimension for bone analysis
by Peter Fratzl - 309-310 Homed to the hideout
by Wolf-Dietrich Hardt - 310-311 Growing planet brought to light
by Zhaohuan Zhu - 311-312 On the crest of becoming vertebrate
by Marianne E. Bronner - 312-314 Organ-seeking vesicles
by Janusz Rak - 314-315 Boost for movement
by Randolph J. Nudo - 315-316 Ecosystem responses to climate extremes
by Anja Rammig & Miguel D. Mahecha - 317-322 Dpp spreading is required for medial but not for lateral wing disc growth
by Stefan Harmansa & Fisun Hamaratoglu & Markus Affolter & Emmanuel Caussinus - 323-328 Novel antibody–antibiotic conjugate eliminates intracellular S. aureus
by Sophie M. Lehar & Thomas Pillow & Min Xu & Leanna Staben & Kimberly K. Kajihara & Richard Vandlen & Laura DePalatis & Helga Raab & Wouter L. Hazenbos & J. Hiroshi Morisaki & Janice Kim & Summer Park & Martine Darwish & Byoung-Chul Lee & Hilda Hernandez & Kelly M. Loyet & Patrick Lupardus & Rina Fong & Donghong Yan & Cecile Chalouni & Elizabeth Luis & Yana Khalfin & Emile Plise & Jonathan Cheong & Joseph P. Lyssikatos & Magnus Strandh & Klaus Koefoed & Peter S. Andersen & John A. Flygare & Man Wah Tan & Eric J. Brown & Sanjeev Mariathasan - 329-335 Tumour exosome integrins determine organotropic metastasis
by Ayuko Hoshino & Bruno Costa-Silva & Tang-Long Shen & Goncalo Rodrigues & Ayako Hashimoto & Milica Tesic Mark & Henrik Molina & Shinji Kohsaka & Angela Di Giannatale & Sophia Ceder & Swarnima Singh & Caitlin Williams & Nadine Soplop & Kunihiro Uryu & Lindsay Pharmer & Tari King & Linda Bojmar & Alexander E. Davies & Yonathan Ararso & Tuo Zhang & Haiying Zhang & Jonathan Hernandez & Joshua M. Weiss & Vanessa D. Dumont-Cole & Kimberly Kramer & Leonard H. Wexler & Aru Narendran & Gary K. Schwartz & John H. Healey & Per Sandstrom & Knut Jørgen Labori & Elin H. Kure & Paul M. Grandgenett & Michael A. Hollingsworth & Maria de Sousa & Sukhwinder Kaur & Maneesh Jain & Kavita Mallya & Surinder K. Batra & William R. Jarnagin & Mary S. Brady & Oystein Fodstad & Volkmar Muller & Klaus Pantel & Andy J. Minn & Mina J. Bissell & Benjamin A. Garcia & Yibin Kang & Vinagolu K. Rajasekhar & Cyrus M. Ghajar & Irina Matei & Hector Peinado & Jacqueline Bromberg & David Lyden - 336-341 Gating machinery of InsP3R channels revealed by electron cryomicroscopy
by Guizhen Fan & Matthew L. Baker & Zhao Wang & Mariah R. Baker & Pavel A. Sinyagovskiy & Wah Chiu & Steven J. Ludtke & Irina I. Serysheva - 342-344 Accreting protoplanets in the LkCa 15 transition disk
by S. Sallum & K. B. Follette & J. A. Eisner & L. M. Close & P. Hinz & K. Kratter & J. Males & A. Skemer & B. Macintosh & P. Tuthill & V. Bailey & D. Defrère & K. Morzinski & T. Rodigas & E. Spalding & A. Vaz & A. J. Weinberger - 349-352 Nanostructure surveys of macroscopic specimens by small-angle scattering tensor tomography
by Marianne Liebi & Marios Georgiadis & Andreas Menzel & Philipp Schneider & Joachim Kohlbrecher & Oliver Bunk & Manuel Guizar-Sicairos - 353-356 Six-dimensional real and reciprocal space small-angle X-ray scattering tomography
by Florian Schaff & Martin Bech & Paul Zaslansky & Christoph Jud & Marianne Liebi & Manuel Guizar-Sicairos & Franz Pfeiffer - 357-361 Methane storage in flexible metal–organic frameworks with intrinsic thermal management
by Jarad A. Mason & Julia Oktawiec & Mercedes K. Taylor & Matthew R. Hudson & Julien Rodriguez & Jonathan E. Bachman & Miguel I. Gonzalez & Antonio Cervellino & Antonietta Guagliardi & Craig M. Brown & Philip L. Llewellyn & Norberto Masciocchi & Jeffrey R. Long - 362-366 North Pacific deglacial hypoxic events linked to abrupt ocean warming
by S. K. Praetorius & A. C. Mix & M. H. Walczak & M. D. Wolhowe & J. A. Addison & F. G. Prahl - 367-370 The effects of life history and sexual selection on male and female plumage colouration
by James Dale & Cody J. Dey & Kaspar Delhey & Bart Kempenaers & Mihai Valcu - 371-374 Migratory neuronal progenitors arise from the neural plate borders in tunicates
by Alberto Stolfi & Kerrianne Ryan & Ian A. Meinertzhagen & Lionel Christiaen - 375-378 Decapentaplegic and growth control in the developing Drosophila wing
by Takuya Akiyama & Matthew C. Gibson - 379-383 Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
by Shiran Rabinovich & Lital Adler & Keren Yizhak & Alona Sarver & Alon Silberman & Shani Agron & Noa Stettner & Qin Sun & Alexander Brandis & Daniel Helbling & Stanley Korman & Shalev Itzkovitz & David Dimmock & Igor Ulitsky & Sandesh C. S. Nagamani & Eytan Ruppin & Ayelet Erez - 384-388 DNA-dependent formation of transcription factor pairs alters their binding specificity
by Arttu Jolma & Yimeng Yin & Kazuhiro R. Nitta & Kashyap Dave & Alexander Popov & Minna Taipale & Martin Enge & Teemu Kivioja & Ekaterina Morgunova & Jussi Taipale - 389-393 Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
by Tina Thorslund & Anita Ripplinger & Saskia Hoffmann & Thomas Wild & Michael Uckelmann & Bine Villumsen & Takeo Narita & Titia K. Sixma & Chunaram Choudhary & Simon Bekker-Jensen & Niels Mailand - 394-397 The inner workings of the hydrazine synthase multiprotein complex
by Andreas Dietl & Christina Ferousi & Wouter J. Maalcke & Andreas Menzel & Simon de Vries & Jan T. Keltjens & Mike S. M. Jetten & Boran Kartal & Thomas R. M. Barends - 398-398 Erratum: Arithmetic and local circuitry underlying dopamine prediction errors
by Neir Eshel & Michael Bukwich & Vinod Rao & Vivian Hemmelder & Ju Tian & Naoshige Uchida - 398-398 Correction: Corrigendum: Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment
by E. M. Alexandrova & A. R. Yallowitz & D. Li & S. Xu & R. Schulz & D. A. Proia & G. Lozano & M. Dobbelstein & U. M. Moll - 398-398 Correction: Corrigendum: Whole–genome characterization of chemoresistant ovarian cancer
by Ann-Marie Patch & Elizabeth L. Christie & Dariush Etemadmoghadam & Dale W. Garsed & Joshy George & Sian Fereday & Katia Nones & Prue Cowin & Kathryn Alsop & Peter J. Bailey & Karin S. Kassahn & Felicity Newell & Michael C. J. Quinn & Stephen Kazakoff & Kelly Quek & Charlotte Wilhelm-Benartzi & Ed Curry & Huei San Leong & Anne Hamilton & Linda Mileshkin & George Au-Yeung & Catherine Kennedy & Jillian Hung & Yoke-Eng Chiew & Paul Harnett & Michael Friedlander & Michael Quinn & Jan Pyman & Stephen Cordner & Patricia O’Brien & Jodie Leditschke & Greg Young & Kate Strachan & Paul Waring & Walid Azar & Chris Mitchell & Nadia Traficante & Joy Hendley & Heather Thorne & Mark Shackleton & David K. Miller & Gisela Mir Arnau & Richard W. Tothill & Timothy P. Holloway & Timothy Semple & Ivon Harliwong & Craig Nourse & Ehsan Nourbakhsh & Suzanne Manning & Senel Idrisoglu & Timothy J. C. Bruxner & Angelika N. Christ & Barsha Poudel & Oliver Holmes & Matthew Anderson & Conrad Leonard & Andrew Lonie & Nathan Hall & Scott Wood & Darrin F. Taylor & Qinying Xu & J. Lynn Fink & Nick Waddell & Ronny Drapkin & Euan Stronach & Hani Gabra & Robert Brown & Andrea Jewell & Shivashankar H. Nagaraj & Emma Markham & Peter J. Wilson & Jason Ellul & Orla McNally & Maria A. Doyle & Ravikiran Vedururu & Collin Stewart & Ernst Lengyel & John V. Pearson & Nicola Waddell & Anna deFazio & Sean M. Grimmond & David D. L. Bowtell - 398-398 Erratum: A positional Toll receptor code directs convergent extension in Drosophila
by Adam C. Paré & Athea Vichas & Christopher T. Fincher & Zachary Mirman & Dene L. Farrell & Avantika Mainieri & Jennifer A. Zallen - 399-401 Lab transitions: The bumpy road to relocation
by Paul Smaglik - 401-401 Turning point: Daniel Carder
by Virginia Gewin - 404-404 Age progression
by Susana Martinez-Conde
November 2015, Volume 527, Issue 7577
- 49-49 Nature Index 2015 Collaborations
by Michelle Grayson & Stephen Pincock - 58-59 Comment: A well-connected world
by Jonathan Adams & Tamar Loach - 135-135 China must act decisively to eradicate the ivory trade
by Li Zhang - 137-137 Scientists debate mega-microbiome initiatives
by Rachel Becker - 141-142 Keystone XL decision puts spotlight on US climate politics
by Jeff Tollefson - 142-143 Arecibo Observatory director quits after funding row
by Traci Watson - 144-145 Uncertainty for UK science ahead of giant spending review
by Daniel Cressey & Elizabeth Gibney - 145-145 Mega science prize split between 1,377 physicists
by Zeeya Merali - 146-146 Canada creates science-minister post
by Nicola Jones - 146-147 Leukaemia success heralds wave of gene-editing therapies
by Sara Reardon - 148-151 Science and sexism: In the eye of the Twitterstorm
by Lauren Morello - 152-154 New life for pig-to-human transplants
by Sara Reardon - 155-158 Biological research: Rethink biosafety
by Tim Trevan - 159-161 CRISPR: A path through the thicket
by Debra J. H. Mathews & Sarah Chan & Peter J. Donovan & Thomas Douglas & Christopher Gyngell & John Harris & Alan Regenberg & Robin Lovell-Badge - 162-163 Cancer therapy: Up close and personalized
by Gerard Evan - 163-163 Books in brief
by Barbara Kiser - 164-164 History of science: Trial by gender
by Jennifer Rampling - 165-165 Lessons from Madrid for next climate talks
by Benjamin D. Santer - 165-165 Drug pollution: Europe responds
by Hubertus Cranz & Richard Bergström & Adrian van den Hoven - 165-165 Drug pollution: industry responds
by Jason Snape & Wesley White - 165-165 Account for soil as natural capital
by Carl Obst - 165-165 Irked by naivety about policymaking
by Kathryn Oliver & Adam Wellstead & Paul Cairney - 168-169 DNA repair without flipping out
by David S. Shin & John A. Tainer - 169-170 A small star with an Earth-like planet
by Drake Deming - 170-171 The enemy of my enemy is my friend
by Isaac S. Harris & Joan S. Brugge - 172-173 Deadly combination
by Robert Duncan - 173-174 A rewired food web
by Julia L. Blanchard - 174-175 Liquefied molecular holes
by Michael Mastalerz - 176-177 Human sleep before the industrial era
by Derk-Jan Dijk & Anne C. Skeldon - 177-178 Higher costs of climate change
by Thomas Sterner - 179-185 Basomedial amygdala mediates top-down control of anxiety and fear
by Avishek Adhikari & Talia N. Lerner & Joel Finkelstein & Sally Pak & Joshua H. Jennings & Thomas J. Davidson & Emily Ferenczi & Lisa A. Gunaydin & Julie J. Mirzabekov & Li Ye & Sung-Yon Kim & Anna Lei & Karl Deisseroth - 186-191 Oxidative stress inhibits distant metastasis by human melanoma cells
by Elena Piskounova & Michalis Agathocleous & Malea M. Murphy & Zeping Hu & Sara E. Huddlestun & Zhiyu Zhao & A. Marilyn Leitch & Timothy M. Johnson & Ralph J. DeBerardinis & Sean J. Morrison - 192-197 BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
by Matthew C. Canver & Elenoe C. Smith & Falak Sher & Luca Pinello & Neville E. Sanjana & Ophir Shalem & Diane D. Chen & Patrick G. Schupp & Divya S. Vinjamur & Sara P. Garcia & Sidinh Luc & Ryo Kurita & Yukio Nakamura & Yuko Fujiwara & Takahiro Maeda & Guo-Cheng Yuan & Feng Zhang & Stuart H. Orkin & Daniel E. Bauer - 198-203 Cryo-electron microscopy structure of the Slo2.2 Na+-activated K+ channel
by Richard K. Hite & Peng Yuan & Zongli Li & Yichun Hsuing & Thomas Walz & Roderick MacKinnon - 204-207 A rocky planet transiting a nearby low-mass star
by Zachory K. Berta-Thompson & Jonathan Irwin & David Charbonneau & Elisabeth R. Newton & Jason A. Dittmann & Nicola Astudillo-Defru & Xavier Bonfils & Michaël Gillon & Emmanuël Jehin & Antony A. Stark & Brian Stalder & Francois Bouchy & Xavier Delfosse & Thierry Forveille & Christophe Lovis & Michel Mayor & Vasco Neves & Francesco Pepe & Nuno C. Santos & Stéphane Udry & Anaël Wünsche - 208-211 Entangling two transportable neutral atoms via local spin exchange
by A. M. Kaufman & B. J. Lester & M. Foss-Feig & M. L. Wall & A. M. Rey & C. A. Regal - 212-215 Large anomalous Hall effect in a non-collinear antiferromagnet at room temperature
by Satoru Nakatsuji & Naoki Kiyohara & Tomoya Higo - 216-220 Liquids with permanent porosity
by Nicola Giri & Mario G. Del Pópolo & Gavin Melaugh & Rebecca L. Greenaway & Klaus Rätzke & Tönjes Koschine & Laure Pison & Margarida F. Costa Gomes & Andrew I. Cooper & Stuart L. James - 221-225 Plate tectonics on the Earth triggered by plume-induced subduction initiation
by T. V. Gerya & R. J. Stern & M. Baes & S. V. Sobolev & S. A. Whattam - 226-230 Widespread exploitation of the honeybee by early Neolithic farmers
by Mélanie Roffet-Salque & Martine Regert & Richard P. Evershed & Alan K. Outram & Lucy J. E. Cramp & Orestes Decavallas & Julie Dunne & Pascale Gerbault & Simona Mileto & Sigrid Mirabaud & Mirva Pääkkönen & Jessica Smyth & Lucija Šoberl & Helen L. Whelton & Alfonso Alday-Ruiz & Henrik Asplund & Marta Bartkowiak & Eva Bayer-Niemeier & Lotfi Belhouchet & Federico Bernardini & Mihael Budja & Gabriel Cooney & Miriam Cubas & Ed M. Danaher & Mariana Diniz & László Domboróczki & Cristina Fabbri & Jesus E. González-Urquijo & Jean Guilaine & Slimane Hachi & Barrie N. Hartwell & Daniela Hofmann & Isabel Hohle & Juan J. Ibáñez & Necmi Karul & Farid Kherbouche & Jacinta Kiely & Kostas Kotsakis & Friedrich Lueth & James P. Mallory & Claire Manen & Arkadiusz Marciniak & Brigitte Maurice-Chabard & Martin A. Mc Gonigle & Simone Mulazzani & Mehmet Özdoğan & Olga S. Perić & Slaviša R. Perić & Jörg Petrasch & Anne-Marie Pétrequin & Pierre Pétrequin & Ulrike Poensgen & C. Joshua Pollard & François Poplin & Giovanna Radi & Peter Stadler & Harald Stäuble & Nenad Tasić & Dushka Urem-Kotsou & Jasna B. Vuković & Fintan Walsh & Alasdair Whittle & Sabine Wolfram & Lydia Zapata-Peña & Jamel Zoughlami - 231-234 Deep-time evolution of regeneration and preaxial polarity in tetrapod limb development
by Nadia B. Fröbisch & Constanze Bickelmann & Jennifer C. Olori & Florian Witzmann - 235-239 Global non-linear effect of temperature on economic production
by Marshall Burke & Solomon M. Hsiang & Edward Miguel - 240-244 Oxygen regulation of breathing through an olfactory receptor activated by lactate
by Andy J. Chang & Fabian E. Ortega & Johannes Riegler & Daniel V. Madison & Mark A. Krasnow - 245-248 Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A
by Jin-Hua Sun & Donald R. O’Boyle II & Robert A. Fridell & David R. Langley & Chunfu Wang & Susan B. Roberts & Peter Nower & Benjamin M. Johnson & Frederic Moulin & Michelle J. Nophsker & Ying-Kai Wang & Mengping Liu & Karen Rigat & Yong Tu & Piyasena Hewawasam & John Kadow & Nicholas A. Meanwell & Mark Cockett & Julie A. Lemm & Melissa Kramer & Makonen Belema & Min Gao - 249-253 Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
by Dongjun Peng & Ilona Kryczek & Nisha Nagarsheth & Lili Zhao & Shuang Wei & Weimin Wang & Yuqing Sun & Ende Zhao & Linda Vatan & Wojciech Szeliga & Jan Kotarski & Rafał Tarkowski & Yali Dou & Kathleen Cho & Sharon Hensley-Alford & Adnan Munkarah & Rebecca Liu & Weiping Zou - 254-258 The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions
by Elwood A. Mullins & Rongxin Shi & Zachary D. Parsons & Philip K. Yuen & Sheila S. David & Yasuhiro Igarashi & Brandt F. Eichman - 259-263 Structure of a eukaryotic SWEET transporter in a homotrimeric complex
by Yuyong Tao & Lily S. Cheung & Shuo Li & Joon-Seob Eom & Li-Qing Chen & Yan Xu & Kay Perry & Wolf B. Frommer & Liang Feng - 264-264 Correction: Corrigendum: Recoded organisms engineered to depend on synthetic amino acids
by Alexis J. Rovner & Adrian D. Haimovich & Spencer R. Katz & Zhe Li & Michael W. Grome & Brandon M. Gassaway & Miriam Amiram & Jaymin R. Patel & Ryan R. Gallagher & Jesse Rinehart & Farren J. Isaacs - 264-264 Erratum: Structural imprints in vivo decode RNA regulatory mechanisms
by Robert C. Spitale & Ryan A. Flynn & Qiangfeng Cliff Zhang & Pete Crisalli & Byron Lee & Jong-Wha Jung & Hannes Y. Kuchelmeister & Pedro J. Batista & Eduardo A. Torre & Eric T. Kool & Howard Y. Chang - 264-264 Correction: Corrigendum: Biocontainment of genetically modified organisms by synthetic protein design
by Daniel J. Mandell & Marc J. Lajoie & Michael T. Mee & Ryo Takeuchi & Gleb Kuznetsov & Julie E. Norville & Christopher J. Gregg & Barry L. Stoddard & George M. Church - 265-266 Non-profit organizations: Scientists on a mission
by Julie Gould - 266-266 Trade talk: Policy analyst
by Julie Gould - 268-268 System reboot
by Jeremy Szal
November 2015, Volume 527, Issue 7576
- 1-1 Big data in biomedicine
by Eric Bender - 2-4 Big data: The power of petabytes
by Michael Eisenstein - 5-5 Q&A: Mark Caulfield
by Claire Ainsworth - 6-7 Proteomics: High-protein research
by Neil Savage - 8-9 Collaborations: Mining the motherlodes
by Katherine Bourzac - 9-9 Avoid major disasters by welcoming minor change
by Len Fisher - 10-11 Cancer: Reshaping the cancer clinic
by Charlie Schmidt - 11-11 Does innovation always come from science?
by Alexandra Witze - 12-13 Mobile data: Made to measure
by Neil Savage - 14-15 Deep phenotyping: The details of disease
by Cathryn M. Delude - 15-16 Memory-boosting devices tested in humans
by Sara Reardon - 16-17 Historic Rosetta mission to end with crash into comet
by Elizabeth Gibney - 16-17 Perspective: Sustaining the big-data ecosystem
by Philip E. Bourne & Jon R. Lorsch & Eric D. Green - 18-18 Q&A: Perry Nisen
by Eric Bender - 18-18 Indonesia blazes threaten endangered orangutans
by Nadia Drake - 19-19 Synthetic biology lures Silicon Valley investors
by Erika Check Hayden - 19-19 Big data in biomedicine: 4 big questions
by Eric Bender - 20-20 Indian scientists join protests over killings of prominent secularists
by T. V. Padma - 20-21 Software predicts slew of fiendish crystal structures
by Elizabeth Gibney - 22-25 The big baby experiment
by Linda Geddes - 26-29 The greatest vanishing act in prehistoric America
by Richard Monastersky - 31-32 Informatics: Make sense of health data
by Julian H. Elliott & Jeremy Grimshaw & Russ Altman & Lisa Bero & Steven N. Goodman & David Henry & Malcolm Macleod & David Tovey & Peter Tugwell & Howard White & Ida Sim - 33-34 Society: Build digital democracy
by Dirk Helbing & Evangelos Pournaras