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The calcium sensor synaptotagmin 7 is required for synaptic facilitation

Author

Listed:
  • Skyler L. Jackman

    (Harvard Medical School)

  • Josef Turecek

    (Harvard Medical School)

  • Justine E. Belinsky

    (Harvard Medical School)

  • Wade G. Regehr

    (Harvard Medical School)

Abstract

Synaptotagmin 7 is shown to be essential for synaptic facilitation at a variety of central synapses, and the results pave the way for future functional studies of short-term synaptic plasticity, a fundamental form of neuronal computation.

Suggested Citation

  • Skyler L. Jackman & Josef Turecek & Justine E. Belinsky & Wade G. Regehr, 2016. "The calcium sensor synaptotagmin 7 is required for synaptic facilitation," Nature, Nature, vol. 529(7584), pages 88-91, January.
  • Handle: RePEc:nat:nature:v:529:y:2016:i:7584:d:10.1038_nature16507
    DOI: 10.1038/nature16507
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    Cited by:

    1. Kevin C. Courtney & Taraknath Mandal & Nikunj Mehta & Lanxi Wu & Yueqi Li & Debasis Das & Qiang Cui & Edwin R. Chapman, 2023. "Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration," Nature Communications, Nature, vol. 14(1), pages 1-15, December.

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