IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0217648.html
   My bibliography  Save this article

The association between subjective caregiver burden and depressive symptoms in carers of older relatives: A systematic review and meta-analysis

Author

Listed:
  • Rafael del-Pino-Casado
  • Marta Rodríguez Cardosa
  • Catalina López-Martínez
  • Vasiliki Orgeta

Abstract

Background: Family carers are an important source of care for older people. Although several studies have reported that subjective caregiver burden is related to depressive symptoms there are no systematic reviews quantifying this association. Objective: To establish the extent to which subjective caregiver burden is associated with depressive symptoms and whether this association would vary by study or care characteristics. Methods: We searched major databases such as PubMed, CINAHL, PsycINFO, Scopus and ISI Proceedings up to March 2018, and conducted a meta-analysis of included studies. Summary estimates of the association were obtained using a random-effects model to improve generalisation of findings. Results: After screening of 4,688 articles, 55 studies were included providing a total of 56 independent comparisons with a total of 9,847 carers from data across 20 countries. There was a large, positive association between subjective caregiver burden and depressive symptoms (r¯ = 0.514; 95% CI = 0.486, 0.541), with very low heterogeneity amongst individual studies (I2 = 8.6%). Sensitivity analyses showed no differences between cross-sectional or repeated measures (r¯ = 0.521; 95% CI = 0.491, 0.550; 51 samples) and longitudinal studies (r¯ = 0.454; 95% CI = 0.398, 0.508; 6 samples). We found a higher effect size for those caring for people living with dementia compared to those caring for frail older people, and stroke survivors. Carer sex, age and kinship did not change the estimate of the effect. Conclusions: Subjective caregiver burden is a significant risk factor for depressive symptoms in carers of older people and may precipitate clinical depression. Those caring for people with dementia experience greater burden. There is a need for longitudinal evaluations examining the effects of potential mediators of the association of subjective burden and depressive symptoms. Future interventions should test whether minimizing subjective burden may modify the risk of developing depression in carers of older relatives.

Suggested Citation

  • Rafael del-Pino-Casado & Marta Rodríguez Cardosa & Catalina López-Martínez & Vasiliki Orgeta, 2019. "The association between subjective caregiver burden and depressive symptoms in carers of older relatives: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 14(5), pages 1-16, May.
    • Handle: RePEc:plo:pone00:0217648
    DOI: 10.1371/journal.pone.0217648
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217648
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0217648&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0217648?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Martin Pinquart & Silvia Sörensen, 2003. "Associations of Stressors and Uplifts of Caregiving With Caregiver Burden and Depressive Mood: A Meta-Analysis," The Journals of Gerontology: Series B, The Gerontological Society of America, vol. 58(2), pages 112-128.
    2. Sue Duval & Richard Tweedie, 2000. "Trim and Fill: A Simple Funnel-Plot–Based Method of Testing and Adjusting for Publication Bias in Meta-Analysis," Biometrics, The International Biometric Society, vol. 56(2), pages 455-463, June.
    3. Rafael del-Pino-Casado & Antonio Frías-Osuna & Pedro A Palomino-Moral & María Ruzafa-Martínez & Antonio J Ramos-Morcillo, 2018. "Social support and subjective burden in caregivers of adults and older adults: A meta-analysis," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-18, January.
    4. Alessandro Liberati & Douglas G Altman & Jennifer Tetzlaff & Cynthia Mulrow & Peter C Gøtzsche & John P A Ioannidis & Mike Clarke & P J Devereaux & Jos Kleijnen & David Moher, 2009. "The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-28, July.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Lawrence B. Sacco & Stefanie König & Hugo Westerlund & Loretta G. Platts, 2022. "Informal Caregiving and Quality of Life Among Older Adults: Prospective Analyses from the Swedish Longitudinal Occupational Survey of Health (SLOSH)," Social Indicators Research: An International and Interdisciplinary Journal for Quality-of-Life Measurement, Springer, vol. 160(2), pages 845-866, April.
    2. Aliya Zhylkybekova & Gulbakit K. Koshmaganbetova & Afshin Zare & Nadiar M. Mussin & Asset A. Kaliyev & Shabnam Bakhshalizadeh & Nurgul Ablakimova & Andrej M. Grjibovski & Natalya Glushkova & Amin Tama, 2024. "Global Research on Care-Related Burden and Quality of Life of Informal Caregivers for Older Adults: A Bibliometric Analysis," Sustainability, MDPI, vol. 16(3), pages 1-18, January.
    3. Sara Santini & Marco Socci & Paolo Fabbietti & Giovanni Lamura & Andrea Teti, 2022. "Factors Worsening and Mitigating the Consequences of the COVID-19 Outbreak on the Overall Health of Informal Caregivers of Older People with Long-Term Care Needs Living in Germany and in Italy," IJERPH, MDPI, vol. 19(3), pages 1-21, February.
    4. Joanne R. Campione & Katarzyna A. Zebrak, 2022. "The Chosen Child: Characteristics of Family Caregivers Selected at an Early Age to Provide Care to Their Parents," Journal of Elder Policy, John Wiley & Sons, vol. 2(1), pages 29-49, March.
    5. Takashi Oshio & Kemmyo Sugiyama, 2022. "Social Participation as a Moderator for Caregivers’ Psychological Distress: a Dynamic Panel Data Model Analysis in Japan," Applied Research in Quality of Life, Springer;International Society for Quality-of-Life Studies, vol. 17(3), pages 1813-1829, June.
    6. Diego Montano & Richard Peter, 2022. "Informal care-giving and the intention to give up employment: the role of perceived supervisor behaviour in a cohort of German employees," European Journal of Ageing, Springer, vol. 19(3), pages 575-585, September.
    7. Rafael del-Pino-Casado & Emilia Priego-Cubero & Catalina López-Martínez & Vasiliki Orgeta, 2021. "Subjective caregiver burden and anxiety in informal caregivers: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(3), pages 1-20, March.
    8. Marie Agapitos & Graciela Muniz-Terrera & Annie Robitaille, 2024. "Older caregivers’ depressive symptomatology over time: evidence from the Survey of Health, Ageing and Retirement in Europe," European Journal of Ageing, Springer, vol. 21(1), pages 1-14, December.
    9. Cristina Gagliardi & Flavia Piccinini & Giovanni Lamura & Georgia Casanova & Paolo Fabbietti & Marco Socci, 2022. "The Burden of Caring for Dependent Older People and the Resultant Risk of Depression in Family Primary Caregivers in Italy," Sustainability, MDPI, vol. 14(6), pages 1-18, March.
    10. Jinpitcha Mamom & Hanvedes Daovisan, 2022. "Listening to Caregivers’ Voices: The Informal Family Caregiver Burden of Caring for Chronically Ill Bedridden Elderly Patients," IJERPH, MDPI, vol. 19(1), pages 1-15, January.
    11. Perla Werner & Aviad Tur-Sinai & Hanan AboJabel, 2021. "Examining Dementia Family Caregivers’ Forgone Care for General Practitioners and Medical Specialists during a COVID-19 Lockdown," IJERPH, MDPI, vol. 18(7), pages 1-11, April.
    12. Ronald Kamoga & Vincent Mubangizi & Judith Owokuhaisa & Moses Muwanguzi & Sylivia Natakunda & Godfrey Zari Rukundo, 2023. "Behavioral and Psychological Symptoms of Dementia: Prevalence, Symptom Severity, and Caregiver Distress in South-Western Uganda—A Quantitative Cross-Sectional Study," IJERPH, MDPI, vol. 20(3), pages 1-12, January.
    13. Tatjana Rajovic & Natasa Todorovic & Milutin Vracevic & Nina Rajovic & Andrija Pavlovic & Vedrana Pavlovic & Igor Grbic & Rosa Sapic & Slavica Krsmanovic & Marijana Vukmirovic & Tamara Stanisavljevic , 2021. "From Burden to Depressive Symptoms in Informal Caregivers during the COVID-19 Pandemic: A Path Analysis," IJERPH, MDPI, vol. 18(18), pages 1-13, September.
    14. David Feligreras-Alcalá & Antonio Frías-Osuna & Rafael del-Pino-Casado, 2020. "Personal and Family Resources Related to Depressive and Anxiety Symptoms in Women during Puerperium," IJERPH, MDPI, vol. 17(14), pages 1-14, July.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Rafael del-Pino-Casado & Antonio Frías-Osuna & Pedro A Palomino-Moral & María Ruzafa-Martínez & Antonio J Ramos-Morcillo, 2018. "Social support and subjective burden in caregivers of adults and older adults: A meta-analysis," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-18, January.
    2. Damiano Pizzol & Mike Trott & Igor Grabovac & Mario Antunes & Anna Claudia Colangelo & Simona Ippoliti & Cristian Petre Ilie & Anne Carrie & Nicola Veronese & Lee Smith, 2021. "Laparoscopy in Low-Income Countries: 10-Year Experience and Systematic Literature Review," IJERPH, MDPI, vol. 18(11), pages 1-11, May.
    3. Meng Cao & Minghui Quan & Jie Zhuang, 2019. "Effect of High-Intensity Interval Training versus Moderate-Intensity Continuous Training on Cardiorespiratory Fitness in Children and Adolescents: A Meta-Analysis," IJERPH, MDPI, vol. 16(9), pages 1-13, April.
    4. Tang, Xinfeng & Tang, Suqin & Ren, Zhihong & Wong, Daniel Fu Keung, 2020. "Psychological risk and protective factors associated with depressive symptoms among adolescents in secondary schools in China: A systematic review and meta-analysis," Children and Youth Services Review, Elsevier, vol. 108(C).
    5. Ricardo M. Hodann-Caudevilla & Cintia Díaz-Silveira & Francisco A. Burgos-Julián & Miguel A. Santed, 2020. "Mindfulness-Based Interventions for People with Schizophrenia: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(13), pages 1-18, June.
    6. Daniele Nucci & Cristina Fatigoni & Andrea Amerio & Anna Odone & Vincenza Gianfredi, 2020. "Red and Processed Meat Consumption and Risk of Depression: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(18), pages 1-20, September.
    7. Tomohide Yamada & Kazuo Hara & Hitomi Umematsu & Ryo Suzuki & Takashi Kadowaki, 2012. "Erectile Dysfunction and Cardiovascular Events in Diabetic Men: A Meta-analysis of Observational Studies," PLOS ONE, Public Library of Science, vol. 7(9), pages 1-7, September.
    8. Ramya Ramamoorthi & Daniel Gahreman & Timothy Skinner & Simon Moss, 2019. "The effect of yoga practice on glycemic control and other health parameters in the prediabetic state: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 14(10), pages 1-21, October.
    9. Carmela A White & Bob Uttl & Mark D Holder, 2019. "Meta-analyses of positive psychology interventions: The effects are much smaller than previously reported," PLOS ONE, Public Library of Science, vol. 14(5), pages 1-48, May.
    10. Amy J Morgan & Anna Ross & Nicola J Reavley, 2018. "Systematic review and meta-analysis of Mental Health First Aid training: Effects on knowledge, stigma, and helping behaviour," PLOS ONE, Public Library of Science, vol. 13(5), pages 1-20, May.
    11. Jong Seung Kim & Sam Hyun Kwon, 2016. "Mupirocin in the Treatment of Staphylococcal Infections in Chronic Rhinosinusitis: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-11, December.
    12. Meng-Ni Wu & Ping-Tao Tseng & Tien-Yu Chen & Yen-Wen Chen & Li-Min Liou & Pao-Yen Lin & Chung-Yao Hsu, 2018. "The efficacy and tolerability of rotigotine on patients with periodic limb movement in sleep: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 13(4), pages 1-15, April.
    13. William Kofi Bosu & Siobhan Theresa Reilly & Justice Moses Kwaku Aheto & Eugenio Zucchelli, 2019. "Hypertension in older adults in Africa: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 14(4), pages 1-25, April.
    14. Agustín Manresa-Rocamora & José Manuel Sarabia & Alejandro Javaloyes & Andrew A. Flatt & Manuel Moya-Ramón, 2021. "Heart Rate Variability-Guided Training for Enhancing Cardiac-Vagal Modulation, Aerobic Fitness, and Endurance Performance: A Methodological Systematic Review with Meta-Analysis," IJERPH, MDPI, vol. 18(19), pages 1-22, September.
    15. Meng Cao & Yucheng Tang & Shu Li & Yu Zou, 2021. "Effects of High-Intensity Interval Training and Moderate-Intensity Continuous Training on Cardiometabolic Risk Factors in Overweight and Obesity Children and Adolescents: A Meta-Analysis of Randomized," IJERPH, MDPI, vol. 18(22), pages 1-22, November.
    16. Moses N. Ikiugu & Whitney Lucas-Molitor & Diana Feldhacker & Cassidy Gebhart & Mallory Spier & Lauren Kapels & Riley Arnold & Rebecca Gaikowski, 2019. "Guidelines for Occupational Therapy Interventions Based on Meaningful and Psychologically Rewarding Occupations," Journal of Happiness Studies, Springer, vol. 20(7), pages 2027-2053, October.
    17. Xiaoli Liu & Guichuan Huang & Jing Zhang & Longju Zhang & Zongan Liang, 2020. "Prognostic and clinicopathological significance of long noncoding RNA MALAT-1 expression in patients with non-small cell lung cancer: A meta-analysis," PLOS ONE, Public Library of Science, vol. 15(10), pages 1-16, October.
    18. Xiaowen Li & Xing Rong & Zhi Wang & Aihua Lin, 2020. "Association between Smoking and Noise-Induced Hearing Loss: A Meta-Analysis of Observational Studies," IJERPH, MDPI, vol. 17(4), pages 1-14, February.
    19. Joan Puig-Barberà & Sonia Tamames-Gómez & Pedro Plans-Rubio & José María Eiros-Bouza, 2022. "Relative Effectiveness of Cell-Cultured versus Egg-Based Seasonal Influenza Vaccines in Preventing Influenza-Related Outcomes in Subjects 18 Years Old or Older: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 19(2), pages 1-20, January.
    20. Xiaofeng Zhou & Guan Zhang & Ye Tian, 2015. "p53 Status Correlates with the Risk of Recurrence in Non-Muscle Invasive Bladder Cancers Treated with Bacillus Calmette–Guérin: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-12, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0217648. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.