IDEAS home Printed from https://ideas.repec.org/a/eee/phsmap/v635y2024ics0378437124000311.html
   My bibliography  Save this article

Mixed synaptic modulation and inhibitory plasticity perform complementary roles in metastable transitions

Author

Listed:
  • Zhou, Xinjia
  • Zhang, Yan
  • Gu, Tianyi
  • Zheng, Muhua
  • Xu, Kesheng

Abstract

Metastable transitions of neural populations have been tackled from deterministic chaos and stochastic neural noise (or fluctuations) perspectives, with a few research works investigating metastable transitions from the perspective of mixed synaptic modulation and inhibitory short-term plasticity (ISTP). We explore what happens when synaptic weights are modified by electrical coupling and inhibitory plasticity in firing activities, and we provide three statistical analyses for capturing network activities and metastable transitions. We show that the mixed synaptic modulation and ISTP play different roles in metastable transitions of the excitatory networks. ISTP increases net inhibition for suppressing metastable states, giving rise to a straight-line phase transition between various firing modes. In contrast, electrical coupling significantly drives the line of this phase transition. The presented results bridge a few gaps in our understanding of the mechanism of coexisting firing patterns and the metastable transition when relevant parameters of synaptic strengths are varied.

Suggested Citation

  • Zhou, Xinjia & Zhang, Yan & Gu, Tianyi & Zheng, Muhua & Xu, Kesheng, 2024. "Mixed synaptic modulation and inhibitory plasticity perform complementary roles in metastable transitions," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 635(C).
    • Handle: RePEc:eee:phsmap:v:635:y:2024:i:c:s0378437124000311
    DOI: 10.1016/j.physa.2024.129523
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0378437124000311
    Download Restriction: Full text for ScienceDirect subscribers only. Journal offers the option of making the article available online on Science direct for a fee of $3,000
    File URL: https://libkey.io/10.1016/j.physa.2024.129523?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Wang, Xinyi & Zhang, Xiyun & Zheng, Muhua & Xu, Leijun & Xu, Kesheng, 2023. "Noise-induced coexisting firing patterns in hybrid-synaptic interacting networks," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 615(C).
    2. Lee Cossell & Maria Florencia Iacaruso & Dylan R. Muir & Rachael Houlton & Elie N. Sader & Ho Ko & Sonja B. Hofer & Thomas D. Mrsic-Flogel, 2015. "Functional organization of excitatory synaptic strength in primary visual cortex," Nature, Nature, vol. 518(7539), pages 399-403, February.
    3. Daniel Levenstein & György Buzsáki & John Rinzel, 2019. "NREM sleep in the rodent neocortex and hippocampus reflects excitable dynamics," Nature Communications, Nature, vol. 10(1), pages 1-12, December.
    4. Zhou, Xinjia & Tian, Changhai & Zhang, Xiyun & Zheng, Muhua & Xu, Kesheng, 2022. "Short-term plasticity as a mechanism to regulate and retain multistability," Chaos, Solitons & Fractals, Elsevier, vol. 165(P1).
    5. Wei-Chung Allen Lee & Vincent Bonin & Michael Reed & Brett J. Graham & Greg Hood & Katie Glattfelder & R. Clay Reid, 2016. "Anatomy and function of an excitatory network in the visual cortex," Nature, Nature, vol. 532(7599), pages 370-374, April.
    6. Zengcai V. Guo & Hidehiko K. Inagaki & Kayvon Daie & Shaul Druckmann & Charles R. Gerfen & Karel Svoboda, 2017. "Maintenance of persistent activity in a frontal thalamocortical loop," Nature, Nature, vol. 545(7653), pages 181-186, May.
    7. James A. Roberts & Leonardo L. Gollo & Romesh G. Abeysuriya & Gloria Roberts & Philip B. Mitchell & Mark W. Woolrich & Michael Breakspear, 2019. "Metastable brain waves," Nature Communications, Nature, vol. 10(1), pages 1-17, December.
    8. L. F. Abbott & Wade G. Regehr, 2004. "Synaptic computation," Nature, Nature, vol. 431(7010), pages 796-803, October.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Bettina Voelcker & Ravi Pancholi & Simon Peron, 2022. "Transformation of primary sensory cortical representations from layer 4 to layer 2," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    2. Bartul Mimica & Tuçe Tombaz & Claudia Battistin & Jingyi Guo Fuglstad & Benjamin A. Dunn & Jonathan R. Whitlock, 2023. "Behavioral decomposition reveals rich encoding structure employed across neocortex in rats," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
    3. Yoav Printz & Pritish Patil & Mathias Mahn & Asaf Benjamin & Anna Litvin & Rivka Levy & Max Bringmann & Ofer Yizhar, 2023. "Determinants of functional synaptic connectivity among amygdala-projecting prefrontal cortical neurons in male mice," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
    4. Gabriel Koch Ocker & Krešimir Josić & Eric Shea-Brown & Michael A Buice, 2017. "Linking structure and activity in nonlinear spiking networks," PLOS Computational Biology, Public Library of Science, vol. 13(6), pages 1-47, June.
    5. Stefano Recanatesi & Gabriel Koch Ocker & Michael A Buice & Eric Shea-Brown, 2019. "Dimensionality in recurrent spiking networks: Global trends in activity and local origins in connectivity," PLOS Computational Biology, Public Library of Science, vol. 15(7), pages 1-29, July.
    6. Hang Zhou & Guo-Qiang Bi & Guosong Liu, 2024. "Intracellular magnesium optimizes transmission efficiency and plasticity of hippocampal synapses by reconfiguring their connectivity," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
    7. Oren Amsalem & Hidehiko Inagaki & Jianing Yu & Karel Svoboda & Ran Darshan, 2024. "Sub-threshold neuronal activity and the dynamical regime of cerebral cortex," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    8. Zhihao Zheng & Christopher S. Own & Adrian A. Wanner & Randal A. Koene & Eric W. Hammerschmith & William M. Silversmith & Nico Kemnitz & Ran Lu & David W. Tank & H. Sebastian Seung, 2024. "Fast imaging of millimeter-scale areas with beam deflection transmission electron microscopy," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    9. Benjamin J. Griffiths & Tino Zaehle & Stefan Repplinger & Friedhelm C. Schmitt & Jürgen Voges & Simon Hanslmayr & Tobias Staudigl, 2022. "Rhythmic interactions between the mediodorsal thalamus and prefrontal cortex precede human visual perception," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    10. Wen-Hao Zhang & Si Wu & Krešimir Josić & Brent Doiron, 2023. "Sampling-based Bayesian inference in recurrent circuits of stochastic spiking neurons," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    11. Dominik P. Koller & Michael Schirner & Petra Ritter, 2024. "Human connectome topology directs cortical traveling waves and shapes frequency gradients," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
    12. Manish Saggar & James M. Shine & Raphaël Liégeois & Nico U. F. Dosenbach & Damien Fair, 2022. "Precision dynamical mapping using topological data analysis reveals a hub-like transition state at rest," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
    13. Jérémie Sibille & Carolin Gehr & Jonathan I. Benichov & Hymavathy Balasubramanian & Kai Lun Teh & Tatiana Lupashina & Daniela Vallentin & Jens Kremkow, 2022. "High-density electrode recordings reveal strong and specific connections between retinal ganglion cells and midbrain neurons," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    14. Gianluca Milano & Alessandro Cultrera & Luca Boarino & Luca Callegaro & Carlo Ricciardi, 2023. "Tomography of memory engrams in self-organizing nanowire connectomes," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    15. Wang, Xinyi & Zhang, Xiyun & Zheng, Muhua & Xu, Leijun & Xu, Kesheng, 2023. "Noise-induced coexisting firing patterns in hybrid-synaptic interacting networks," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 615(C).
    16. Zhou, Xinjia & Tian, Changhai & Zhang, Xiyun & Zheng, Muhua & Xu, Kesheng, 2022. "Short-term plasticity as a mechanism to regulate and retain multistability," Chaos, Solitons & Fractals, Elsevier, vol. 165(P1).
    17. Yifan Gu & Yang Qi & Pulin Gong, 2019. "Rich-club connectivity, diverse population coupling, and dynamical activity patterns emerging from local cortical circuits," PLOS Computational Biology, Public Library of Science, vol. 15(4), pages 1-34, April.
    18. Giacomo Valle & Natalija Katic Secerovic & Dominic Eggemann & Oleg Gorskii & Natalia Pavlova & Francesco M. Petrini & Paul Cvancara & Thomas Stieglitz & Pavel Musienko & Marko Bumbasirevic & Stanisa R, 2024. "Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    19. Carles Bosch & Tobias Ackels & Alexandra Pacureanu & Yuxin Zhang & Christopher J. Peddie & Manuel Berning & Norman Rzepka & Marie-Christine Zdora & Isabell Whiteley & Malte Storm & Anne Bonnin & Chris, 2022. "Functional and multiscale 3D structural investigation of brain tissue through correlative in vivo physiology, synchrotron microtomography and volume electron microscopy," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    20. André, Morgan & Planche, Léo, 2021. "The effect of graph connectivity on metastability in a stochastic system of spiking neurons," Stochastic Processes and their Applications, Elsevier, vol. 131(C), pages 292-310.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:phsmap:v:635:y:2024:i:c:s0378437124000311. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.journals.elsevier.com/physica-a-statistical-mechpplications/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.