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Analysis of the mitigation strategies for COVID-19: From mathematical modelling perspective

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  • Kassa, Semu M.
  • Njagarah, John B.H.
  • Terefe, Yibeltal A.

Abstract

In this article, a mathematical model for the transmission of COVID-19 disease is formulated and analysed. It is shown that the model exhibits a backward bifurcation at R0=1 when recovered individuals do not develop a permanent immunity for the disease. In the absence of reinfection, it is proved that the model is without backward bifurcation and the disease free equilibrium is globally asymptotically stable for R0<1. By using available data, the model is validated and parameter values are estimated. The sensitivity of the value of R0 to changes in any of the parameter values involved in its formula is analysed. Moreover, various mitigation strategies are investigated using the proposed model and it is observed that the asymptomatic infectious group of individuals may play the major role in the re-emergence of the disease in the future. Therefore, it is recommended that in the absence of vaccination, countries need to develop capacities to detect and isolate at least 30% of the asymptomatic infectious group of individuals while treating in isolation at least 50% of symptomatic patients to control the disease.

Suggested Citation

  • Kassa, Semu M. & Njagarah, John B.H. & Terefe, Yibeltal A., 2020. "Analysis of the mitigation strategies for COVID-19: From mathematical modelling perspective," Chaos, Solitons & Fractals, Elsevier, vol. 138(C).
  • Handle: RePEc:eee:chsofr:v:138:y:2020:i:c:s0960077920303672
    DOI: 10.1016/j.chaos.2020.109968
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    References listed on IDEAS

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    1. Ndaïrou, Faïçal & Area, Iván & Nieto, Juan J. & Torres, Delfim F.M., 2020. "Mathematical modeling of COVID-19 transmission dynamics with a case study of Wuhan," Chaos, Solitons & Fractals, Elsevier, vol. 135(C).
    2. Qureshi, Sania & Yusuf, Abdullahi, 2019. "Modeling chickenpox disease with fractional derivatives: From caputo to atangana-baleanu," Chaos, Solitons & Fractals, Elsevier, vol. 122(C), pages 111-118.
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    12. Huda Abdul Satar & Raid Kamel Naji, 2023. "A Mathematical Study for the Transmission of Coronavirus Disease," Mathematics, MDPI, vol. 11(10), pages 1-20, May.
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    15. Asamoah, Joshua Kiddy K. & Owusu, Mark A. & Jin, Zhen & Oduro, F. T. & Abidemi, Afeez & Gyasi, Esther Opoku, 2020. "Global stability and cost-effectiveness analysis of COVID-19 considering the impact of the environment: using data from Ghana," Chaos, Solitons & Fractals, Elsevier, vol. 140(C).
    16. Mishra, Bimal Kumar & Keshri, Ajit Kumar & Saini, Dinesh Kumar & Ayesha, Syeda & Mishra, Binay Kumar & Rao, Yerra Shankar, 2021. "Mathematical model, forecast and analysis on the spread of COVID-19," Chaos, Solitons & Fractals, Elsevier, vol. 147(C).
    17. Vashishth, Anil K. & Basaiti, Komal, 2024. "Modeling the effect of non-pharmaceutical measures and vaccination on the spread of two variants of COVID-19 in India," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 217(C), pages 139-168.
    18. Ndenda, J.P. & Njagarah, J.B.H. & Shaw, S., 2021. "Role of immunotherapy in tumor-immune interaction: Perspectives from fractional-order modelling and sensitivity analysis," Chaos, Solitons & Fractals, Elsevier, vol. 148(C).
    19. Miraj Ahmed Bhuiyan & Tiziana Crovella & Annarita Paiano & Helena Alves, 2021. "A Review of Research on Tourism Industry, Economic Crisis and Mitigation Process of the Loss: Analysis on Pre, During and Post Pandemic Situation," Sustainability, MDPI, vol. 13(18), pages 1-27, September.
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