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Content
April 1999, Volume 398, Issue 6727
- 513-517 Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
by Michael S. Wolfe & Weiming Xia & Beth L. Ostaszewski & Thekla S. Diehl & W. Taylor Kimberly & Dennis J. Selkoe - 518-522 A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
by Bart De Strooper & Wim Annaert & Philippe Cupers & Paul Saftig & Katleen Craessaerts & Jeffrey S. Mumm & Eric H. Schroeter & Vincent Schrijvers & Michael S. Wolfe & William J. Ray & Alison Goate & Raphael Kopan - 522-525 Presenilin is required for activity and nuclear access of Notch in Drosophila
by Gary Struhl & Iva Greenwald - 525-529 Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants
by Yihong Ye & Nina Lukinova & Mark E. Fortini - 530-533 The motor protein myosin-I produces its working stroke in two steps
by Claudia Veigel & Lynne M. Coluccio & James D. Jontes & John C. Sparrow & Ronald A. Milligan & Justin E. Molloy - 533-538 Structural basis for self-association and receptor recognition of human TRAF2
by Young Chul Park & Vicki Burkitt & Anthony R. Villa & Liang Tong & Hao Wu
April 1999, Volume 398, Issue 6726
- 4-5 Stability offers unique opportunity for research
by Colin Macilwain - 7-9 Scientists seek support from Mexican public
by Laura Garwin - 10-10 Customs delays drive researchers to smuggling
by Colin Macilwain - 11-12 Chile tries to bridge gap in scientific standards
by Colin Macilwain - 13-13 Andes observatories belatedly take root
by Roland Pease - 14-15 Community split on Peronist reform effort
by Colin Macilwain - 16-18 Collapse of réal sharpens Brazil's contrasts
by Colin Macilwain - 19-19 Brazil's space programme comes of age
by Tony Reichhardt - 20-21 Resources lacking to save Amazon biodiversity
by Andrea Kauffmann-Zeh - 22-23 Cuban biotechnology treads a lonely path
by Kimberly Carr - 355-355 Local residents unimpressed by growth plan
by Ehsan Masood - 355-356 Wellcome wages battle to house companies next to genome labs
by Ehsan Masood - 356-356 New Howard Hughes head seeks bioinformatics boost
by Colin Macilwain - 356-356 Scientists welcome Prodi as European Commission president
by Alison Abbott - 357-357 Wyoming physics faculty faces closure
by Tony Reichhardt - 357-357 Geological problems drive up cost of nuclear waste dump in Japan
by Asako Saegusa - 358-358 Cosmic-ray observatory in Argentina gets go-ahead
by Alison Abbott - 358-358 Court suspends pioneering gene deal in Yellowstone
by Colin Macilwain - 358-358 Canadian scientists win over rare species
by David Spurgeon - 359-359 US concern grows over secrecy clauses
by Steve Nadis - 359-359 UK research councils look to future needs
by Natasha Loder - 360-360 Biotech industry seeks ‘honest brokers’
by Declan Butler - 360-360 Asians link up to protect plant resources
by K. S. Jayaraman - 361-361 Women scientists unite to battle cowboy culture
by Steve Nadis - 365-365 Budget shock hits Danish universities
by Kaj Sand-Jensen - 365-365 High priests of science fear for their position
by George Lauer - 365-366 Harpoons fly in whale wars
by Alan Macnow - 366-366 System values seniority over innovation
by I. A. Brown - 366-366 Harpoons fly in whale wars
by Steve Palumbi & Frank Cipriano - 367-368 Phage-lift for game theory
by Martin A. Nowak & Karl Sigmund - 368-369 A burst caught in flagrante
by Peter Mészáros - 369-369 Spit and polish off
by John Whitfield - 371-372 Crash tests for real
by Robert M. May - 372-375 Phonons rewrite structural recipes
by Mark S. T. Bukowinski - 375-376 A unity of opposites
by Ethan Bier - 376-376 Millennium bug
by R. S. Siew - 377-378 Sugars slide into heparin activity
by Pierre Sinaÿ - 378-379 And there was light!
by Robert Apfel - 379-379 Oscillating enzymes
by David Jones - 380-380 Gertrude Belle Elion (1918-99)
by Richard Kent & Brian Huber - 381-381 Angiogenesis inhibited by drinking tea
by Yihai Cao & Renhai Cao - 382-382 Trimethylamine induces migration of waterfleas
by Hinnerk Boriss & Maarten Boersma & Karen H. Wiltshire - 382-383 Ancient stunted trees on cliffs
by D. W. Larson & U. Matthes & J. A. Gerrath & J. M. Gerrath & J. C. Nekola & G. L. Walker & S. Porembski & A. Charlton & N. W. K. Larson - 383-384 Molecular basis of triclosan activity
by Colin W. Levy & Anna Roujeinikova & Svetlana Sedelnikova & Patrick J. Baker & Antoine R. Stuitje & Antoni R. Slabas & David W. Rice & John B. Rafferty - 385-385 Evolutionists red in tooth and claw
by David L. Hull - 385-387 On from Babylon
by J. D. North - 387-387 The laying on of genes
by Karol Sikora - 387-388 An explosive laboratory
by Ilkka Hanski - 388-388 Science in culture
by Martin Kemp - 389-394 The afterglow, redshift and extreme energetics of the γ-ray burst of 23 January 1999
by S. R. Kulkarni & S. G. Djorgovski & S. C. Odewahn & J. S. Bloom & R. R. Gal & C. D. Koresko & F. A. Harrison & L. M. Lubin & L. Armus & R. Sari & G. D. Illingworth & D. D. Kelson & D. K. Magee & P. G. van Dokkum & D. A. Frail & J. S. Mulchaey & M. A. Malkan & I. S. McClean & H. I. Teplitz & D. Koerner & D. Kirkpatrick & N. Kobayashi & I.-A. Yadigaroglu & J. Halpern & T. Piran & R. W. Goodrich & F. H. Chaffee & M. Feroci & E. Costa - 394-399 The effect of magnetic fields on γ-ray bursts inferred from multi-wavelength observations of the burst of 23 January 1999
by T. J. Galama & M. S. Briggs & R. A. M. J. Wijers & P. M. Vreeswijk & E. Rol & D. Band & J. van Paradijs & C. Kouveliotou & R. D. Preece & M. Bremer & I. A. Smith & R. P. J. Tilanus & A. G. de Bruyn & R. G. Strom & G. Pooley & A. J. Castro-Tirado & N. Tanvir & C. Robinson & K. Hurley & J. Heise & J. Telting & R. G. M. Rutten & C. Packham & R. Swaters & J. K. Davies & A. Fassia & S. F. Green & M. J. Foster & R. Sagar & A. K. Pandey & Nilakshi & R. K. S. Yadav & E. O. Ofek & E. Leibowitz & P. Ibbetson & J. Rhoads & E. Falco & C. Petry & C. Impey & T. R. Geballe & D. Bhattacharya - 400-402 Observation of contemporaneous optical radiation from a γ-ray burst
by C. Akerlof & R. Balsano & S. Barthelmy & J. Bloch & P. Butterworth & D. Casperson & T. Cline & S. Fletcher & F. Frontera & G. Gisler & J. Heise & J. Hills & R. Kehoe & B. Lee & S. Marshall & T. McKay & R. Miller & L. Piro & W. Priedhorsky & J. Szymanski & J. Wren - 402-405 A simple explanation of light emission in sonoluminescence
by Sascha Hilgenfeldt & Siegfried Grossmann & Detlef Lohse - 405-407 Immobility of protons in ice from 30 to 190 K
by J. P. Cowin & A. A. Tsekouras & M. J. Iedema & K. Wu & G. B. Ellison - 407-410 Electrical conduction through DNA molecules
by Hans-Werner Fink & Christian Schönenberger - 410-413 Glacial–interglacial changes in ocean surface conditions in the Southern Hemisphere
by F. Vimeux & V. Masson & J. Jouzel & M. Stievenard & J. R. Petit - 413-415 Gravity-driven continental overflow and Archaean tectonics
by R. C. Bailey - 415-417 Absolute measures of the completeness of the fossil record
by Mike Foote & J. John Sepkoski - 417-422 Synthesis of thrombin-inhibiting heparin mimetics without side effects
by Maurice Petitou & Jean-Pascal Hérault & André Bernat & Pierre-Alexandre Driguez & Philippe Duchaussoy & Jean-Claude Lormeau & Jean-Marc Herbert - 422-426 β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
by Osamu Tetsu & Frank McCormick - 427-431 Local inhibition and long-range enhancement of Dpp signal transduction by Sog
by Hilary L. Ashe & Michael Levine - 431-436 A new secreted protein that binds to Wnt proteins and inhibits their activites
by Jen-Chih Hsieh & Laurent Kodjabachian & Martha L. Rebbert & Amir Rattner & Philip M. Smallwood & Cynthia Harryman Samos & Roel Nusse & Igor B. Dawid & Jeremy Nathans - 436-441 A capsaicin-receptor homologue with a high threshold for noxious heat
by Michael J. Caterina & Tobias A. Rosen & Makoto Tominaga & Anthony J. Brake & David Julius - 441-443 Prisoner's dilemma in an RNA virus
by Paul E. Turner & Lin Chao
March 1999, Volume 398, Issue 6725
- 271-271 Nuclear waste store could be built within 25 years, say Lords
by Ehsan Masood - 271-271 Gaps remain in knowledge of waste behaviour
by Ehsan Masood - 272-272 Unease mounts over Japan's reform plan
by Asako Saegusa - 272-272 Libraries offer incentive for web-based rivals to ‘costly’ journals
by Meredith Wadman - 273-273 Husbands a drag to high-flying physicists
by Natasha Loder - 273-273 California approves $1.5 billion campus
by Rex Dalton - 274-274 Embattled French science agency says it is holding its own
by Declan Butler - 274-274 Dispute erupts over Nazi research claims
by Quirin Schiermeier - 275-275 ‘Don't try to change embryo research law’
by Alison Abbott - 275-275 CERN plan to train science entrepreneurs
by Alison Abbott - 276-276 Weapon lab security may hit foreign visits
by Wil Lepkowski - 276-276 Trade unions campaign for lifelong learning
by Ehsan Masood - 277-277 UK life scientists seek wider Foresight role
by Ehsan Masood - 277-277 Minister slams ‘mismanaged’ universities
by Michael Cherry - 280-280 Franklin recalled
by Brenda Maddox - 280-280 It's time to stop counting beans
by David A. Watson - 280-280 Researchers face ‘Catch-22’ grants trap
by Carlos F. Ibáñez - 281-282 Is science dangerous?
by Lewis Wolpert - 283-284 At the roots of the mammalian family tree
by Timothy Rowe - 284-285 Table-top picosecond sources
by Justin Wark - 285-287 Good reception in fruitfly antennae
by Yitzhak Pilpel & Doron Lancet - 288-289 The pulling power of galaxy clusters
by Peter Coles - 289-291 Europe's winter prospects
by Yochanan Kushnir - 291-292 The eyes have it!
by Karl Gegenfurtner - 292-293 Free oscillations illuminate the mantle
by R. Widmer-Schnidrig - 293-294 Phytoplankton death in the sea
by David L. Kirchman - 294-295 The elusive ‘ultimate state’ of thermal convection
by Joël Sommeria - 295-296 Coming up for air and sporulation
by Nicholas J. Talbot - 296-296 Press-fit chemistry
by David Jones - 297-298 A spelling device for the paralysed
by N. Birbaumer & N. Ghanayim & T. Hinterberger & I. Iversen & B. Kotchoubey & A. Kübler & J. Perelmouter & E. Taub & H. Flor - 298-299 Insect antenna as a smoke detector
by Stefan Schütz & Bernhard Weissbecker & Hans E. Hummel & Karl-Heinz Apel & Helmut Schmitz & Horst Bleckmann - 299-299 Rings of single-walled carbon nanotubes
by Richard Martel & Herbert R. Shea & Phaedon Avouris - 299-300 Taxon sampling revisited
by Steven Poe & David L. Swofford - 301-302 Historical transformations
by William McGinnis & Peter A. Lawrence - 302-303 Painting a picture of development
by John Maynard Smith - 303-303 Surfing a chaotic sea
by J. D. Meiss - 303-304 A bloody business
by Fred S. Rosen - 304-304 Storm-chaser reaps the whirlwind
by Roger A. Pielke - 305-307 Josephson-junction qubits with controlled couplings
by Yuriy Makhlin & Gerd Scöhn & Alexander Shnirman - 307-310 Evidence against ‘ultrahard’ thermal turbulence at very high Rayleigh numbers
by James A. Glazier & Takehiko Segawa & Antoine Naert & Masaki Sano - 310-312 Picosecond–milliångström lattice dynamics measured by ultrafast X-ray diffraction
by Christoph Rose-Petruck & Ralph Jimenez & Ting Guo & Andrea Cavalleri & Craig W. Siders & Ferenc Rksi & Jeff A. Squier & Barry C. Walker & Kent R. Wilson & Christopher P. J. Barty - 312-316 Directed nucleation of calcite at a crystal-imprinted polymer surface
by S. M. D'Souza & C. Alexander & S. W. Carr & A. M. Waller & M. J. Whitcombe & E. N. Vulfson - 316-319 Ubiquity of quasi-horizontal layers in the troposphere
by Reginald E. Newell & Valerie Thouret & John Y. N. Cho & Patrick Stoller & Alain Marenco & Herman G. Smit - 320-323 Oceanic forcing of the wintertime North Atlantic Oscillation and European climate
by M. J. Rodwell & D. P. Rowell & C. K. Folland - 323-326 Distortion of isochronous layers in ice revealed by ground-penetrating radar
by David G. Vaughan & Hugh F. J. Corr & Christopher S. M. Doake & Ed. D. Waddington - 326-330 A Chinese triconodont mammal and mosaic evolution of the mammalian skeleton
by Ji Qiang & Luo Zhexi & Ji Shu-an - 330-334 Strong effects of weak interactions in ecological communities
by E. L. Berlow - 334-338 Anticipation of moving stimuli by the retina
by Michael J. Berry & Iman H. Brivanlou & Thomas A. Jordan & Markus Meister - 338-341 A new cellular mechanism for coupling inputs arriving at different cortical layers
by Matthew E. Larkum & J. Julius Zhu & Bert Sakmann - 341-344 Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells
by Christian Kurts & Francis R. Carbone & Matthew F. Krummel & Karl M. Koch & Jacques F. A. P. Miller & William R. Heath - 344-348 Effects of altered gene order or orientation of the locus control region on human β-globin gene expression in mice
by Keiji Tanimoto & Qinghui Liu & Jörg Bungert & James Douglas Engel - 348-351 Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease
by Klaus Leonhard & Alexandra Stiegler & Walter Neupert & Thomas Langer
March 1999, Volume 398, Issue 6724
- 177-177 Human Genome Project aims to finish ‘working draft’ next year
by Meredith Wadman - 177-177 Britain sought to speed-up sequencing efforts
by Ehsan Masood - 178-178 French ministries seek way out of lab supplies crisis
by Declan Butler - 178-178 Doñana clean-up ‘left half the soil still contaminated’
by Xavier Bosch - 179-179 WHO's bioethics code likely to stir debate
by Declan Butler - 179-179 India falls into line over patents legislation
by K. S. Jayaraman - 180-180 US quest for AIDS vaccine appoints a leader
by Meredith Wadman - 180-180 Call for a lighter regulatory burden on NIH researchers
by Meredith Wadman - 181-181 Britain's ‘high-tech’ budget praised⃛
by Ehsan Masood - 181-181 ⃛ in the push for a knowledge-driven economy
by Ehsan Masood - 182-182 Students win pay rise in Michigan strike
by Wil Lepkowski - 182-182 Japanese emissions plan under fire for relying on nuclear power
by Asako Saegusa - 183-183 European archive for mouse mutants is set to open at last
by Alison Abbott - 186-186 Whales, science and activism
by Sidney J. Holt - 186-186 Many a slip 'twixt cup and lip
by Jens C. Jensenius - 186-186 Words go missing in cyberspace
by Rosie Redfield - 186-186 Words go missing in cyberspace
by Jorge Golowasch & Tania Bedrax-Weiss & Adrián Palacios - 187-188 Lessons from Iraq on bioweapons
by Christian Seelos - 189-190 Bell's inequality test: more ideal than ever
by Alain Aspect - 190-190 Oryx go back to the brink
by Martyn Gorman - 191-193 Ageing hard or hardly ageing?
by David Kipling & Richard G. A. Faragher - 193-194 Research enters a new phase
by A. J. Millis - 194-195 Neolithic genetic engineering
by Svante Pääbo - 195-198 Bose gases and their Fermi cousins
by Michael R. Andrews - 198-199 A new-for-old urinary bladder
by Jeffrey A. Hubbell - 199-200 Testing time for theories
by D. V. Ahluwalia - 200-201 Modification by nuclear export?
by Patrick G. Hogan & Anjana Rao - 201-201 Sweeping the seas
by David Jones - 202-202 Henry W. Kendall (1926-99)
by Kurt Gottfried - 203-204 Colour categories in a stone-age tribe
by Jules Davidoff & Ian Davies & Debi Roberson - 204-205 Why biodiversity surveys are good value
by Andrew Balmford & Kevin J. Gaston - 205-206 How the ‘terror crocodile’ grew so big
by Gregory M. Erickson & Christopher A. Brochu - 206-207 Localization or classical diffusion of light?
by Frank Scheffold & Ralf Lenke & Ralf Tweer & Georg Maret - 207-207 Localization or classical diffusion of light?
by Diederik S. Wiersma & Jaime Gómez Rivas & Paolo Bartolini & Ad Lagendijk & Roberto Righini - 208-208 Simulating the motion of gas bubbles in a liquid
by R. Krishna & J. M. van Baten - 209-210 Tale of a stigma redeemed
by Richard Davenport-Hines - 210-210 In retrospect: chosen by Anton Zeilinger
by Anton Zeilinger - 210-211 ⃛ nor any drop to drink
by Daniel Hillel - 212-212 Sounding out two centuries
by J. Woodhouse - 213-216 Sublimation from icy jets as a probe of the interstellar volatile content of comets
by Geoffrey A. Blake & C. Qi & Michiel R. Hogerheijde & M. A. Gurwell & D. O. Muhleman - 216-218 Gravity-wave interferometers as quantum-gravity detectors
by Giovanni Amelino-Camelia - 218-220 Four-wave mixing with matter waves
by L. Deng & E. W. Hagley & J. Wen & M. Trippenbach & Y. Band & P. S. Julienne & J. E. Simsarian & K. Helmerson & S. L. Rolston & W. D. Phillips - 221-223 Vanishing of phase coherence in underdoped Bi2Sr2CaCu2O8+δ
by J. Corson & R. Mallozzi & J. Orenstein & J. N. Eckstein & I. Bozovic - 223-226 Aerosol-assisted self-assembly of mesostructured spherical nanoparticles
by Yunfeng Lu & Hongyou Fan & Aaron Stump & Timothy L. Ward & Thomas Rieker & C. Jeffrey Brinker - 227-230 Molecular-sieve catalysts for the selective oxidation of linear alkanes by molecular oxygen
by John Meurig Thomas & Robert Raja & Gopinathan Sankar & Robert G. Bell - 230-233 Snowpack production of formaldehyde and its effect on the Arctic troposphere
by Ann Louise Sumner & Paul B. Shepson - 233-236 Increased marine sediment suspension and fluxes following an earthquake
by Robert Thunell & Eric Tappa & Ramon Varela & Martin Llano & Yrene Astor & Frank Muller-Karger & Richard Bohrer - 236-239 The limits of selection during maize domestication
by Rong-Lin Wang & Adrian Stec & Jody Hey & Lewis Lukens & John Doebley - 239-242 Gaze direction controls response gain in primary visual-cortex neurons
by Yves Trotter & Simona Celebrini - 242-246 brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes
by Maki Minami & Noriyuki Kinoshita & Yuko Kamoshida & Hiromu Tanimoto & Tetsuya Tabata - 246-251 A new protease required for cell-cycle progression in yeast
by Shyr-Jiann Li & Mark Hochstrasser - 252-256 The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway
by Jun Ninomiya-Tsuji & Kazuya Kishimoto & Atsushi Hiyama & Jun-ichiro Inoue & Zhaodan Cao & Kunihiro Matsumoto - 256-260 NF-AT activation requires suppression of Crm1-dependent export by calcineurin
by Jiangyu Zhu & Frank McKeon - 265-266 Physics grapples with its image problem
by Helen Gavaghan
March 1999, Volume 398, Issue 6723
- 93-93 Catalonia offers $16m innovation grants
by Xavier Bosch - 93-94 Biologists make plea to NIH to invest in supercomputer centre
by Meredith Wadman - 94-94 US Nobel winners back stem-cell research
by Meredith Wadman - 94-94 Mixed funding fortunes for UK research universities
by Ehsan Masood - 95-95 Japan's transplant law ‘is too stringent’⃛
by Asako Saegusa - 95-95 ⃛ but the pill may be legalized at last
by Asako Saegusa - 96-96 Los Alamos secrets ‘were leaked to China’
by Colin Macilwain - 96-96 Russia protests at US science sanctions
by Carl Levitin - 97-97 Top physics labs ‘must bury the hatchet’
by Colin Macilwain - 97-97 The search for missing mass finds funds for UK researchers
by Ehsan Masood - 98-98 US State Department gets cold feet about cold fusion
by Tony Reichhardt - 98-98 Food scientist in GMO row defends ‘premature’ warning
by Ehsan Masood - 98-98 £150m tax break for research in UK budget
by Ehsan Masood - 99-99 Call for research and education to tackle ‘environmental injustice’
by Tony Reichhardt - 99-99 Africa splits over bar to patents on plants
by Ehsan Masood - 102-102 It's time to ‘out’ the selfish researchers
by Noel C. Harris - 102-102 PMs and policemen are getting younger
by M. de L. Brooke - 103-104 Moving protein heads for breakdown
by Martin Scheffner - 104-105 Probing magnetism in the well
by S. D. Bader - 105-107 The mysterious missing sink
by David W. Schindler - 107-108 Asymmetry the easy way
by Samuel P. Gido - 109-111 Retroshuffling the genomic deck
by Jef D. Boeke & Oxana K. Pickeral