Reconsidering Association Testing Methods Using Single-Variant Test Statistics as Alternatives to Pooling Tests for Sequence Data with Rare Variants
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DOI: 10.1371/journal.pone.0030238
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- Benjamin M Neale & Manuel A Rivas & Benjamin F Voight & David Altshuler & Bernie Devlin & Marju Orho-Melander & Sekar Kathiresan & Shaun M Purcell & Kathryn Roeder & Mark J Daly, 2011. "Testing for an Unusual Distribution of Rare Variants," PLOS Genetics, Public Library of Science, vol. 7(3), pages 1-8, March.
- Iuliana Ionita-Laza & Joseph D Buxbaum & Nan M Laird & Christoph Lange, 2011. "A New Testing Strategy to Identify Rare Variants with Either Risk or Protective Effect on Disease," PLOS Genetics, Public Library of Science, vol. 7(2), pages 1-6, February.
- Thomas J Hoffmann & Nicholas J Marini & John S Witte, 2010. "Comprehensive Approach to Analyzing Rare Genetic Variants," PLOS ONE, Public Library of Science, vol. 5(11), pages 1-9, November.
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- Nanye Long & Samuel P Dickson & Jessica M Maia & Hee Shin Kim & Qianqian Zhu & Andrew S Allen, 2013. "Leveraging Prior Information to Detect Causal Variants via Multi-Variant Regression," PLOS Computational Biology, Public Library of Science, vol. 9(6), pages 1-11, June.
- Xinge Jessie Jeng & Zhongyin John Daye & Wenbin Lu & Jung-Ying Tzeng, 2016. "Rare Variants Association Analysis in Large-Scale Sequencing Studies at the Single Locus Level," PLOS Computational Biology, Public Library of Science, vol. 12(6), pages 1-23, June.
- Rachel Marceau West & Wenbin Lu & Daniel M Rotroff & Melaine A Kuenemann & Sheng-Mao Chang & Michael C Wu & Michael J Wagner & John B Buse & Alison A Motsinger-Reif & Denis Fourches & Jung-Ying Tzeng, 2019. "Identifying individual risk rare variants using protein structure guided local tests (POINT)," PLOS Computational Biology, Public Library of Science, vol. 15(2), pages 1-24, February.
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