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CEP signaling coordinates plant immunity with nitrogen status

Author

Listed:
  • Jakub Rzemieniewski

    (Technical University of Munich)

  • Henriette Leicher

    (Technical University of Munich)

  • Hyun Kyung Lee

    (University of Lausanne)

  • Caroline Broyart

    (University of Lausanne)

  • Shahran Nayem

    (Institute of Biochemical Plant Pathology
    University of Bayreuth)

  • Christian Wiese

    (Technical University of Munich
    Technical University of Munich)

  • Julian Maroschek

    (Technical University of Munich)

  • Zeynep Camgöz

    (Technical University of Munich)

  • Vilde Olsson Lalun

    (University of Oslo)

  • Michael Anthony Djordjevic

    (Australian National University)

  • A. Corina Vlot

    (Institute of Biochemical Plant Pathology
    University of Bayreuth)

  • Ralph Hückelhoven

    (Technical University of Munich)

  • Julia Santiago

    (University of Lausanne)

  • Martin Stegmann

    (Technical University of Munich
    Ulm University)

Abstract

Plant endogenous signaling peptides shape growth, development and adaptations to biotic and abiotic stress. Here, we identify C-TERMINALLY ENCODED PEPTIDEs (CEPs) as immune-modulatory phytocytokines in Arabidopsis thaliana. Our data reveals that CEPs induce immune outputs and are required to mount resistance against the leaf-infecting bacterial pathogen Pseudomonas syringae pv. tomato. We show that effective immunity requires CEP perception by tissue-specific CEP RECEPTOR 1 (CEPR1) and CEPR2. Moreover, we identify the related RECEPTOR-LIKE KINASE 7 (RLK7) as a CEP4-specific CEP receptor contributing to CEP-mediated immunity, suggesting a complex interplay of multiple CEP ligands and receptors in different tissues during biotic stress. CEPs have a known role in the regulation of root growth and systemic nitrogen (N)-demand signaling. We provide evidence that CEPs and their receptors promote immunity in an N status-dependent manner, suggesting a previously unknown molecular crosstalk between plant nutrition and cell surface immunity. We propose that CEPs and their receptors are central regulators for the adaptation of biotic stress responses to plant-available resources.

Suggested Citation

  • Jakub Rzemieniewski & Henriette Leicher & Hyun Kyung Lee & Caroline Broyart & Shahran Nayem & Christian Wiese & Julian Maroschek & Zeynep Camgöz & Vilde Olsson Lalun & Michael Anthony Djordjevic & A. , 2024. "CEP signaling coordinates plant immunity with nitrogen status," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-55194-x
    DOI: 10.1038/s41467-024-55194-x
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