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HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides

Author

Listed:
  • Andra-Octavia Roman

    (University of Lausanne)

  • Pedro Jimenez-Sandoval

    (University of Lausanne)

  • Sebastian Augustin

    (University of Lausanne)

  • Caroline Broyart

    (University of Lausanne)

  • Ludwig A. Hothorn

    (Leibniz University)

  • Julia Santiago

    (University of Lausanne)

Abstract

The membrane receptor kinases HAESA and HSL2 recognize a family of IDA/IDL signaling peptides to control cell separation processes in different plant organs. The homologous HSL1 has been reported to regulate epidermal cell patterning by interacting with a different class of signaling peptides from the CLE family. Here we demonstrate that HSL1 binds IDA/IDL peptides with high, and CLE peptides with lower affinity, respectively. Ligand sensing capability and receptor activation of HSL1 require a SERK co-receptor kinase. Crystal structures with IDA/IDLs or with CLE9 reveal that HSL1-SERK1 complex recognizes the entire IDA/IDL signaling peptide, while only parts of CLE9 are bound to the receptor. In contrast, the receptor kinase BAM1 interacts with the entire CLE9 peptide with high affinity and specificity. Furthermore, the receptor tandem BAM1/BAM2 regulates epidermal cell division homeostasis. Consequently, HSL1-IDLs and BAM1/BAM2-CLEs independently regulate cell patterning in the leaf epidermal tissue.

Suggested Citation

  • Andra-Octavia Roman & Pedro Jimenez-Sandoval & Sebastian Augustin & Caroline Broyart & Ludwig A. Hothorn & Julia Santiago, 2022. "HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-28558-4
    DOI: 10.1038/s41467-022-28558-4
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    1. Jizong Wang & Hongju Li & Zhifu Han & Heqiao Zhang & Tong Wang & Guangzhong Lin & Junbiao Chang & Weicai Yang & Jijie Chai, 2015. "Allosteric receptor activation by the plant peptide hormone phytosulfokine," Nature, Nature, vol. 525(7568), pages 265-268, September.
    2. Leonhard Held, 2020. "A new standard for the analysis and design of replication studies," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 183(2), pages 431-448, February.
    3. Elwira Smakowska-Luzan & G. Adam Mott & Katarzyna Parys & Martin Stegmann & Timothy C Howton & Mehdi Layeghifard & Jana Neuhold & Anita Lehner & Jixiang Kong & Karin Grünwald & Natascha Weinberger & S, 2018. "An extracellular network of Arabidopsis leucine-rich repeat receptor kinases," Nature, Nature, vol. 553(7688), pages 342-346, January.
    4. Elwira Smakowska-Luzan & G. Adam Mott & Katarzyna Parys & Martin Stegmann & Timothy C Howton & Mehdi Layeghifard & Jana Neuhold & Anita Lehner & Jixiang Kong & Karin Grünwald & Natascha Weinberger & S, 2018. "Publisher Correction: An extracellular network of Arabidopsis leucine-rich repeat receptor kinases," Nature, Nature, vol. 561(7722), pages 8-8, September.
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    1. Du-Hwa Lee & Ho-Seok Lee & Min-Soo Choi & Katarzyna Parys & Kaori Honda & Yasumitsu Kondoh & Jung-Min Lee & Natalie Edelbacher & Geon Heo & Balaji Enugutti & Hiroyuki Osada & Ken Shirasu & Youssef Bel, 2024. "Reprogramming of flagellin receptor responses with surrogate ligands," Nature Communications, Nature, vol. 15(1), pages 1-14, December.

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