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Estimation of extra risk and benchmark dose in dose–response models

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  • Gupta, Ramesh C.
  • Wang, Na

Abstract

An important goal in quantitative risk/safety analysis of chemical toxins or pharmaceutical agents is determination of toxic risk posed by exposure to the agent.

Suggested Citation

  • Gupta, Ramesh C. & Wang, Na, 2009. "Estimation of extra risk and benchmark dose in dose–response models," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 79(7), pages 2036-2050.
    • Handle: RePEc:eee:matcom:v:79:y:2009:i:7:p:2036-2050
    DOI: 10.1016/j.matcom.2008.10.003
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    References listed on IDEAS

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    1. Daniela K. Nitcheva & Walter W. Piegorsch & R. Webster West & Ralph L. Kodell, 2005. "Multiplicity-Adjusted Inferences in Risk Assessment: Benchmark Analysis with Quantal Response Data," Biometrics, The International Biometric Society, vol. 61(1), pages 277-286, March.
    2. Mirjam Moerbeek & Aldert H. Piersma & Wout Slob, 2004. "A Comparison of Three Methods for Calculating Confidence Intervals for the Benchmark Dose," Risk Analysis, John Wiley & Sons, vol. 24(1), pages 31-40, February.
    3. Obaid M. Al-Saidy & Walter W. Piegorsch & R. Webster West & Daniela K. Nitcheva, 2003. "Confidence Bands for Low-Dose Risk Estimation with Quantal Response Data," Biometrics, The International Biometric Society, vol. 59(4), pages 1056-1062, December.
    Full references (including those not matched with items on IDEAS)

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