IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v13y2022i1d10.1038_s41467-022-33810-y.html
   My bibliography  Save this article

Temporally programmed polymer – solvent interactions using a chemical reaction network

Author

Listed:
  • Benjamin Klemm

    (Delft University of Technology)

  • Reece W. Lewis

    (Delft University of Technology)

  • Irene Piergentili

    (Delft University of Technology)

  • Rienk Eelkema

    (Delft University of Technology)

Abstract

Out of equilibrium operation of chemical reaction networks (CRNs) enables artificial materials to autonomously respond to their environment by activation and deactivation of intermolecular interactions. Generally, their activation can be driven by various chemical conversions, yet their deactivation to non-interacting building blocks remains largely limited to hydrolysis and internal pH change. To achieve control over deactivation, we present a new, modular CRN that enables reversible formation of positive charges on a tertiary amine substrate, which are removed using nucleophilic signals that control the deactivation kinetics. The modular nature of the CRN enables incorporation in diverse polymer materials, leading to a temporally programmed transition from collapsed and hydrophobic to solvated, hydrophilic polymer chains by controlling polymer-solvent interactions. Depending on the layout of the CRN, we can create stimuli-responsive or autonomously responding materials. This concept will not only offer new opportunities in molecular cargo delivery but also pave the way for next-generation interactive materials.

Suggested Citation

  • Benjamin Klemm & Reece W. Lewis & Irene Piergentili & Rienk Eelkema, 2022. "Temporally programmed polymer – solvent interactions using a chemical reaction network," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
  • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-33810-y
    DOI: 10.1038/s41467-022-33810-y
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-022-33810-y
    File Function: Abstract
    Download Restriction: no

    File URL: https://libkey.io/10.1038/s41467-022-33810-y?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Sarah M. Morrow & Ignacio Colomer & Stephen P. Fletcher, 2019. "A chemically fuelled self-replicator," Nature Communications, Nature, vol. 10(1), pages 1-9, December.
    2. Ignacio Colomer & Sarah M. Morrow & Stephen P. Fletcher, 2018. "A transient self-assembling self-replicator," Nature Communications, Nature, vol. 9(1), pages 1-6, December.
    3. Marta Tena-Solsona & Benedikt Rieß & Raphael K. Grötsch & Franziska C. Löhrer & Caren Wanzke & Benjamin Käsdorf & Andreas R. Bausch & Peter Müller-Buschbaum & Oliver Lieleg & Job Boekhoven, 2017. "Non-equilibrium dissipative supramolecular materials with a tunable lifetime," Nature Communications, Nature, vol. 8(1), pages 1-8, August.
    4. Diederik W. R. Balkenende & Christophe A. Monnier & Gina L. Fiore & Christoph Weder, 2016. "Optically responsive supramolecular polymer glasses," Nature Communications, Nature, vol. 7(1), pages 1-9, April.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Natsumi Nishiie & Ryo Kawatani & Sae Tezuka & Miu Mizuma & Mikihiro Hayashi & Yasuhiro Kohsaka, 2024. "Vitrimer-like elastomers with rapid stress-relaxation by high-speed carboxy exchange through conjugate substitution reaction," Nature Communications, Nature, vol. 15(1), pages 1-9, December.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Fabian Schnitter & Benedikt Rieß & Christian Jandl & Job Boekhoven, 2022. "Memory, switches, and an OR-port through bistability in chemically fueled crystals," Nature Communications, Nature, vol. 13(1), pages 1-8, December.
    2. Xianhua Lang & Yingjie Huang & Lirong He & Yixi Wang & Udayabhaskararao Thumu & Zonglin Chu & Wilhelm T. S. Huck & Hui Zhao, 2023. "Mechanosensitive non-equilibrium supramolecular polymerization in closed chemical systems," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    3. Zhanar Abil & Ana María Restrepo Sierra & Andreea R. Stan & Amélie Châne & Alicia Prado & Miguel Vega & Yannick Rondelez & Christophe Danelon, 2024. "Darwinian Evolution of Self-Replicating DNA in a Synthetic Protocell," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    4. Simone M. Poprawa & Michele Stasi & Brigitte A. K. Kriebisch & Monika Wenisch & Judit Sastre & Job Boekhoven, 2024. "Active droplets through enzyme-free, dynamic phosphorylation," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    5. Changyong Cai & Shuanggen Wu & Yunfei Zhang & Fenfang Li & Zhijian Tan & Shengyi Dong, 2024. "Bulk transparent supramolecular glass enabled by host–guest molecular recognition," Nature Communications, Nature, vol. 15(1), pages 1-9, December.
    6. Ambler, Kate & de Brauw, Alan & Herskowitz, Sylvan & Pulido, Cristhian, 2023. "Viewpoint: Finance needs of the agricultural midstream," Food Policy, Elsevier, vol. 121(C).
    7. Jingjing Li & Yihan Cui & Yi-Lin Lu & Yunfei Zhang & Kaihuang Zhang & Chaonan Gu & Kaifang Wang & Yujia Liang & Chun-Sen Liu, 2023. "Programmable supramolecular chirality in non-equilibrium systems affording a multistate chiroptical switch," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
    8. Jing Chen & Yiyang Gao & Lei Shi & Wei Yu & Zongjie Sun & Yifan Zhou & Shuang Liu & Heng Mao & Dongyang Zhang & Tongqing Lu & Quan Chen & Demei Yu & Shujiang Ding, 2022. "Phase-locked constructing dynamic supramolecular ionic conductive elastomers with superior toughness, autonomous self-healing and recyclability," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    9. Fei Nie & Ke-Zhi Wang & Dongpeng Yan, 2023. "Supramolecular glasses with color-tunable circularly polarized afterglow through evaporation-induced self-assembly of chiral metal–organic complexes," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    10. Keisuke Nakamura & Ryou Kubota & Takuma Aoyama & Kenji Urayama & Itaru Hamachi, 2023. "Four distinct network patterns of supramolecular/polymer composite hydrogels controlled by formation kinetics and interfiber interactions," Nature Communications, Nature, vol. 14(1), pages 1-12, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-33810-y. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.