Pericyte remodeling is deficient in the aged brain and contributes to impaired capillary flow and structure
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-022-33464-w
Download full text from publisher
References listed on IDEAS
- Richard Daneman & Lu Zhou & Amanuel A. Kebede & Ben A. Barres, 2010. "Pericytes are required for blood–brain barrier integrity during embryogenesis," Nature, Nature, vol. 468(7323), pages 562-566, November.
- Annika Armulik & Guillem Genové & Maarja Mäe & Maya H. Nisancioglu & Elisabet Wallgard & Colin Niaudet & Liqun He & Jenny Norlin & Per Lindblom & Karin Strittmatter & Bengt R. Johansson & Christer Bet, 2010. "Pericytes regulate the blood–brain barrier," Nature, Nature, vol. 468(7323), pages 557-561, November.
- Dimitrios Davalos & Jae Kyu Ryu & Mario Merlini & Kim M. Baeten & Natacha Le Moan & Mark A. Petersen & Thomas J. Deerinck & Dimitri S. Smirnoff & Catherine Bedard & Hiroyuki Hakozaki & Sara Gonias Mur, 2012. "Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation," Nature Communications, Nature, vol. 3(1), pages 1-15, January.
- Catherine N. Hall & Clare Reynell & Bodil Gesslein & Nicola B. Hamilton & Anusha Mishra & Brad A. Sutherland & Fergus M. O’Farrell & Alastair M. Buchan & Martin Lauritzen & David Attwell, 2014. "Capillary pericytes regulate cerebral blood flow in health and disease," Nature, Nature, vol. 508(7494), pages 55-60, April.
- K. Shaw & L. Bell & K. Boyd & D. M. Grijseels & D. Clarke & O. Bonnar & H. S. Crombag & C. N. Hall, 2021. "Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
- K. Shaw & L. Bell & K. Boyd & D. M. Grijseels & D. Clarke & O. Bonnar & H. S. Crombag & C. N. Hall, 2021. "Publisher Correction: Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences," Nature Communications, Nature, vol. 12(1), pages 1-1, December.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Alejandro Moreno-Domínguez & Olalla Colinas & Ignacio Arias-Mayenco & José M. Cabeza & Juan L. López-Ogayar & Navdeep S. Chandel & Norbert Weissmann & Natascha Sommer & Alberto Pascual & José López-Ba, 2024. "Hif1α-dependent mitochondrial acute O2 sensing and signaling to myocyte Ca2+ channels mediate arterial hypoxic vasodilation," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Airi Jo-Watanabe & Toshiki Inaba & Takahiro Osada & Ryota Hashimoto & Tomohiro Nishizawa & Toshiaki Okuno & Sayoko Ihara & Kazushige Touhara & Nobutaka Hattori & Masatsugu Oh-Hora & Osamu Nureki & Tak, 2024. "Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Kevin Boyé & Luiz Henrique Geraldo & Jessica Furtado & Laurence Pibouin-Fragner & Mathilde Poulet & Doyeun Kim & Bryce Nelson & Yunling Xu & Laurent Jacob & Nawal Maissa & Dritan Agalliu & Lena Claess, 2022. "Endothelial Unc5B controls blood-brain barrier integrity," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Fan Li & Jazlyn Gallego & Natasha N. Tirko & Jenna Greaser & Derek Bashe & Rudra Patel & Eric Shaker & Grace E. Valkenburg & Alanoud S. Alsubhi & Steven Wellman & Vanshika Singh & Camila Garcia Padill, 2024. "Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation," Nature Communications, Nature, vol. 15(1), pages 1-21, December.
- Yibing Han & Takeshi Tomita & Masayoshi Kato & Norihiro Ashihara & Yumiko Higuchi & Hisanori Matoba & Weiyi Wang & Hikaru Hayashi & Yuji Itoh & Satoshi Takahashi & Hiroshi Kurita & Jun Nakayama & Nobu, 2023. "Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Xinhong Chen & Damien A. Wolfe & Dhanesh Sivadasan Bindu & Mengying Zhang & Naz Taskin & David Goertsen & Timothy F. Shay & Erin E. Sullivan & Sheng-Fu Huang & Sripriya Ravindra Kumar & Cynthia M. Aro, 2023. "Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Satoshi Ii & Hiroki Kitade & Shunichi Ishida & Yohsuke Imai & Yoshiyuki Watanabe & Shigeo Wada, 2020. "Multiscale modeling of human cerebrovasculature: A hybrid approach using image-based geometry and a mathematical algorithm," PLOS Computational Biology, Public Library of Science, vol. 16(6), pages 1-28, June.
- Mohammad Haft-Javaherian & Linjing Fang & Victorine Muse & Chris B Schaffer & Nozomi Nishimura & Mert R Sabuncu, 2019. "Deep convolutional neural networks for segmenting 3D in vivo multiphoton images of vasculature in Alzheimer disease mouse models," PLOS ONE, Public Library of Science, vol. 14(3), pages 1-21, March.
- Kristen Tgavalekos & Thao Pham & Nishanth Krishnamurthy & Angelo Sassaroli & Sergio Fantini, 2019. "Frequency-resolved analysis of coherent oscillations of local cerebral blood volume, measured with near-infrared spectroscopy, and systemic arterial pressure in healthy human subjects," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-27, February.
- Adam Institoris & Milène Vandal & Govind Peringod & Christy Catalano & Cam Ha Tran & Xinzhu Yu & Frank Visser & Cheryl Breiteneder & Leonardo Molina & Baljit S. Khakh & Minh Dang Nguyen & Roger J. Tho, 2022. "Astrocytes amplify neurovascular coupling to sustained activation of neocortex in awake mice," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Pengfei Lu & Ping Wang & Bingruo Wu & Yidong Wang & Yang Liu & Wei Cheng & Xuhui Feng & Xinchun Yuan & Miriam M. Atteya & Haleigh Ferro & Yukiko Sugi & Grant Rydquist & Mahdi Esmaily & Jonathan T. But, 2022. "A SOX17-PDGFB signaling axis regulates aortic root development," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- William A. Mills & AnnaLin M. Woo & Shan Jiang & Joelle Martin & Dayana Surendran & Matthew Bergstresser & Ian F. Kimbrough & Ukpong B. Eyo & Michael V. Sofroniew & Harald Sontheimer, 2022. "Astrocyte plasticity in mice ensures continued endfoot coverage of cerebral blood vessels following injury and declines with age," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Domenic H. Cerri & Daniel L. Albaugh & Lindsay R. Walton & Brittany Katz & Tzu-Wen Wang & Tzu-Hao Harry Chao & Weiting Zhang & Randal J. Nonneman & Jing Jiang & Sung-Ho Lee & Amit Etkin & Catherine N., 2024. "Distinct neurochemical influences on fMRI response polarity in the striatum," Nature Communications, Nature, vol. 15(1), pages 1-23, December.
- Jie Ding & Sung-Jin Lee & Lukas Vlahos & Kanako Yuki & Cara C. Rada & Vincent Unen & Meghah Vuppalapaty & Hui Chen & Asmiti Sura & Aaron K. McCormick & Madeline Tomaske & Samira Alwahabi & Huy Nguyen , 2023. "Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD4-selective WNT surrogate in mice," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Xue Fan Wang & Robin Vigouroux & Michal Syonov & Yuriy Baglaenko & Angeliki M. Nikolakopoulou & Dene Ringuette & Horea Rus & Peter V. DiStefano & Suzie Dufour & Alireza P. Shabanzadeh & Seunggi Lee & , 2024. "The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-33464-w. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.