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Diversity of spatiotemporal coding reveals specialized visual processing streams in the mouse cortex

Author

Listed:
  • Xu Han

    (Neuro-Electronics Research Flanders
    KU Leuven, Department of Biology)

  • Ben Vermaercke

    (Neuro-Electronics Research Flanders
    VIB-KU Leuven Center for Brain & Disease Research)

  • Vincent Bonin

    (Neuro-Electronics Research Flanders
    KU Leuven, Department of Biology
    VIB
    imec)

Abstract

The cerebral cortex contains diverse neural representations of the visual scene, each enabling distinct visual and spatial abilities. However, the extent to which representations are distributed or segregated across cortical areas remains poorly understood. By determining the spatial and temporal responses of >30,000 layer 2/3 pyramidal neurons, we characterize the functional organization of parallel visual streams across eight areas of the mouse cortex. While dorsal and ventral areas form complementary representations of spatiotemporal frequency, motion speed, and spatial patterns, the anterior and posterior dorsal areas show distinct specializations for fast and slow oriented contrasts. At the cellular level, while diverse spatiotemporal tuning lies along a continuum, oriented and non-oriented spatial patterns are encoded by distinct tuning types. The identified tuning types are present across dorsal and ventral streams. The data underscore the highly specific and highly distributed nature of visual cortical representations, which drives specialization of cortical areas and streams.

Suggested Citation

  • Xu Han & Ben Vermaercke & Vincent Bonin, 2022. "Diversity of spatiotemporal coding reveals specialized visual processing streams in the mouse cortex," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
  • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-29656-z
    DOI: 10.1038/s41467-022-29656-z
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    References listed on IDEAS

    as
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    1. Jiashu Liu & Yingtian He & Andreanne Lavoie & Guy Bouvier & Bao-hua Liu, 2023. "A direction-selective cortico-brainstem pathway adaptively modulates innate behaviors," Nature Communications, Nature, vol. 14(1), pages 1-23, December.

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