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Content
March 2000, Volume 404, Issue 6775
- 298-302 Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2
by Yi-Ping Hsueh & Ting-Fang Wang & Fu-Chia Yang & Morgan Sheng - 302-307 Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA
by Raul Mendez & Laura E. Hake & Thorkell Andresson & Laurie E. Littlepage & Joan V. Ruderman & Joel D. Richter - 307-310 The structure of malaria pigment β-haematin
by Silvina Pagola & Peter W. Stephens & D. Scott Bohle & Andrew D. Kosar & Sara K. Madsen - 313-315 Pushing the frontiers of interdisciplinary research: an idea whose time has come
by Diane Gershon - 315-316 Changing the face of training for science at the interface
by Diane Gershon - 316-316 Crossing the divide between theory and practice
by Diane Gershon
March 2000, Volume 404, Issue 6774
- 111-111 Genome leaders told to keep their eyes on the main prize
by Paul Smaglik - 111-111 Revamped GenBank offers extra data links
by Paul Smaglik - 112-112 … and calls for openness and transparency
by David Dickson - 112-112 GM debate must go global, says meeting…
by David Dickson - 113-113 Unesco ‘worse than I imagined,’ says new director
by Natasha Loder - 113-113 China looks to west for economic growth
by Tian Xuewen - 114-114 Expensive space crystal programme has produced little of scientific value, says panel
by Tony Reichhardt - 114-115 Geneticists oppose consent ruling
by Meredith Wadman - 115-115 Panel will seek ‘appropriate’ AIDS goals for South Africa
by Michael Cherry - 115-116 $350m gift boosts MIT brain power
by Steve Nadis - 116-116 Indian research budget favours defence
by K. S. Jayaraman - 117-117 Biology back issues free as publishers walk HighWire
by Declan Butler - 117-117 Rival demands sink genome alliance plans
by Natasha Loder - 120-120 Opportunism knocks?
by Ingo Schubert & Ulrich Wobus - 120-120 Why private institutions alone will not do enough to protect biodiversity
by Alexander James & Kevin J. Gaston & Andrew Balmford - 120-120 Alzheimer's research is vital in work on ageing
by Joseph M. Erwin - 121-122 Rape as an adaptation
by Jerry A. Coyne & Andrew Berry - 122-123 Amassing the case for the defence
by Douglas Palmer - 123-124 Unfinished portrait of the artist
by John Nash - 124-124 Science's stall in the global market-place
by Norman Myers - 125-125 A century of cognitive decline
by Bruce A. Yankner - 127-127 The song of the Neanderthal
by Mark W. Tiedemann - 129-130 Life's downs and ups
by Douglas Erwin - 130-131 Schrödinger's sheep
by Wojciech H. Zurek - 131-133 A chorus line
by Emilio Salinas & Ranulfo Romo - 134-135 Too hot to melt
by A. Lindsay Greer - 135-137 Moving in mysterious ways
by Alison M. Condliffe & Phillip T. Hawkins - 137-138 Pushing electrons around
by Mark Ratner - 138-138 Love is not puffed up
by Amanda Tromans - 139-140 The Antarctic connection
by Richard G. Gordon - 140-140 Expiry date guaranteed
by David Jones - 141-142 Urban benzene and population exposure
by Vincenzo Cocheo & Paolo Sacco & Caterina Boaretto & Emile De Saeger & Pascual Perez Ballesta & Henrik Skov & Eddy Goelen & Norbert Gonzalez & Antonia Baeza Caracena - 142-142 Climate variability and North Sea cod
by Carl M. O'Brien & Clive J. Fox & Benjamin Planque & John Casey - 142-143 Bleaching patterns in reef corals
by B. E. Brown & R. P. Dunne & M. S. Goodson & A. E. Douglas - 143-144 Myopia and ambient night-time lighting
by Karla Zadnik & Lisa A. Jones & Brett C. Irvin & Robert N. Kleinstein & Ruth E. Manny & Julie A. Shin & Donald O. Mutti - 144-144 Myopia and ambient night-time lighting
by J. Gwiazda & E. Ong & R. Held & F. Thorn - 144-144 reply: Myopia and ambient night-time lighting
by Richard A. Stone & Maureen G. Maguire & Graham E. Quinn - 145-150 Cenozoic motion between East and West Antarctica
by Steven C. Cande & Joann M. Stock & R. Dietmar Müller & Takemi Ishihara - 151-158 Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein
by Annette S. Kim & Lazaros T. Kakalis & Norzehan Abdul-Manan & Grace A. Liu & Michael K. Rosen - 159-161 Discovery of calcium in Mercury's atmosphere
by Thomas A. Bida & Rosemary M. Killen & Thomas H. Morgan - 161-164 North–south geological differences between the residual polar caps on Mars
by P. C. Thomas & M. C. Malin & K. S. Edgett & M. H. Carr & W. K. Hartmann & A. P. Ingersoll & P. B. James & L. A. Soderblom & J. Veverka & R. Sullivan - 164-165 Impossibility of deleting an unknown quantum state
by Arun Kumar Pati & Samuel L. Braunstein - 166-168 Molecular control over Au/GaAs diodes
by Ayelet Vilan & Abraham Shanzer & David Cahen - 168-171 Sintering dense nanocrystalline ceramics without final-stage grain growth
by I.-Wei Chen & X.-H. Wang - 171-174 The influence of Antarctic sea ice on glacial–interglacial CO2 variations
by Britton B. Stephens & Ralph F. Keeling - 174-177 Interferometric radar measurements of water level changes on the Amazon flood plain
by Douglas E. Alsdorf & John M. Melack & Thomas Dunne & Leal A. K. Mertes & Laura L. Hess & Laurence C. Smith - 177-180 Delayed biological recovery from extinctions throughout the fossil record
by James W. Kirchner & Anne Weil - 180-183 Simple rules yield complex food webs
by Richard J. Williams & Neo D. Martinez - 183-186 Inhibitory threshold for critical-period activation in primary visual cortex
by Michela Fagiolini & Takao K. Hensch - 187-190 Attention modulates synchronized neuronal firing in primate somatosensory cortex
by P. N. Steinmetz & A. Roy & P. J. Fitzgerald & S. S. Hsiao & K. O. Johnson & E. Niebur - 190-193 Growth patterns in the developing brain detected by using continuum mechanical tensor maps
by Paul M. Thompson & Jay N. Giedd & Roger P. Woods & David MacDonald & Alan C. Evans & Arthur W. Toga - 193-197 A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
by Koichi Akashi & David Traver & Toshihiro Miyamoto & Irving L. Weissman - 197-201 Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Iβ
by Jens Schlossmann & Aldo Ammendola & Keith Ashman & Xiangang Zong & Andrea Huber & Gitte Neubauer & Ge-Xin Wang & Hans-Dieter Allescher & Michael Korth & Matthias Wilm & Franz Hofmann & Peter Ruth - 201-204 hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
by Jong-Soo Lee & Kimberly M. Collins & Alexandra L. Brown & Chang-Hun Lee & Jay H. Chung - 205-208 Ligand binding and conformational motions in myoglobin
by Andreas Ostermann & Robert Waschipky & Fritz G. Parak & G. Ulrich Nienhaus
March 2000, Volume 404, Issue 6773
- 3-3 UK university recruitment in danger
by Natasha Loder - 3-4 Germany challenges human stem cell patent awarded ‘by mistake’
by Quirin Schiermeier - 4-4 Australian jailed for removal of fossilized footprints
by Peter Pockley - 4-4 US energy agency pulls plug on role in genome project
by Colin Macilwain - 5-5 NIH tightens up monitoring of gene-therapy mishaps
by Paul Smaglik - 5-6 Culling plans put future of red deer study in jeopardy
by Natasha Loder - 6-6 US eases Israelis' lab access
by Haim Watzman - 6-6 Young, worldly and unhelpful all miss out on data sharing
by Rex Dalton - 7-7 Promega and Roche take up battle over PCR patents
by Rex Dalton - 7-7 Funding woes spell doom for US radio dish
by Tony Reichhardt - 8-8 Post-Cold War needs ‘new forms of scientific linkage’
by Heather McCabe - 8-8 Canadian budget boost for science
by David Spurgeon - 9-9 Analysis of polio vaccine could end dispute over how AIDS originated
by Declan Butler - 13-13 Patent confusion in law on new plant varieties
by John R. Porter - 13-13 Crowded universities cramp more than just students' style
by Akio Yamamoto - 15-16 Evolution rising from the grave
by Michael A. Goldman - 16-17 Around the world via Greenwich
by J.L. Heilbron - 17-18 A window on scientific progress
by Gunhard Æ. Oravas - 18-18 Science in culture
by John Whitfield - 19-19 Reversing Rorschach
by Richard Gregory - 21-21 Danger — hard hack area
by Paul McAuley - 23-24 Of ice and elephants
by Daniel P. Schrag - 24-25 p53 sends nucleotides to repair DNA
by Guillermina Lozano & Stephen J. Elledge - 25-27 Heartfelt enlightenment
by Ueli Schibler - 28-29 Brane new worlds
by Jerome Gauntlett - 29-31 Imaging in the fourth dimension
by Thomas Elbert & Andreas Keil - 31-31 Beauty is ova-rated
by Rachel Smyly - 32-32 Brimstone on Mars
by Harry Y. McSween - 32-32 Brief lives
by David Jones - 33-33 Errors in judging ‘offside’ in football
by Raôul R. D. Oudejans & Raymond Verheijen & Frank C. Bakker & Jeroen C. Gerrits & Marten Steinbrückner & Peter J. Beek - 34-34 Finding genes in Plasmodium falciparum
by Mihaela Pertea & Steven L. Salzberg & Malcolm J. Gardner - 34-35 Finding genes in Plasmodium falciparum
by Dan Lawson & Sharen Bowman & Bart Barrell - 35-36 Fish do not avoid survey vessels
by P. G. Fernandes & A. S. Brierley & E. J. Simmonds & N. W. Millard & S. D. McPhail & F. Armstrong & P. Stevenson & M. Squires - 36-36 Migration and speciation
by Kevin Winker - 37-41 The importance of repairing stalled replication forks
by Michael M. Cox & Myron F. Goodman & Kenneth N. Kreuzer & David J. Sherratt & Steven J. Sandler & Kenneth J. Marians - 42-49 A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
by Hiroshi Tanaka & Hirofumi Arakawa & Tatsuya Yamaguchi & Kenji Shiraishi & Seisuke Fukuda & Kuniko Matsui & Yoshiki Takei & Yusuke Nakamura - 50-52 Evidence of atmospheric sulphur in the martian regolith from sulphur isotopes in meteorites
by James Farquhar & Joel Savarino & Terri L. Jackson & Mark H. Thiemens - 53-56 Fabrication of photonic crystals for the visible spectrum by holographic lithography
by M. Campbell & D. N. Sharp & M. T. Harrison & R. G. Denning & A. J. Turberfield - 56-59 Electrophoretic assembly of colloidal crystals with optically tunable micropatterns
by R. C. Hayward & D. A. Saville & I. A. Aksay - 59-61 Shape control of CdSe nanocrystals
by Xiaogang Peng & Liberato Manna & Weidong Yang & Juanita Wickham & Erik Scher & Andreas Kadavanich & A. P. Alivisatos - 61-66 Evidence from U–Th dating against Northern Hemisphere forcing of the penultimate deglaciation
by Gideon M. Henderson & Niall C. Slowey - 66-69 Stable sulphate clusters as a source of new atmospheric particles
by Markku Kulmala & Liisa Pirjola & Jyrki M. Mäkelä - 69-72 Geodetic evidence for a low slip rate in the Altyn Tagh fault system
by Rebecca Bendick & Roger Bilham & Jeffrey Freymueller & Kristine Larson & Guanghua Yin - 72-74 Tree species impoverishment and the future flora of the Atlantic forest of northeast Brazil
by José Maria Cardoso da Silva & Marcelo Tabarelli - 74-77 Egg investment is influenced by male attractiveness in the mallard
by Emma J. A. Cunningham & Andrew F. Russell - 77-80 Macaque monkeys categorize images by their ordinal number
by Tanya Orlov & Volodya Yakovlev & Shaul Hochstein & Ehud Zohary - 80-84 Temporal patterns of human cortical activity reflect tone sequence structure
by Aniruddh D. Patel & Evan Balaban - 84-87 Cannabinoids control spasticity and tremor in a multiple sclerosis model
by David Baker & Gareth Pryce & J. Ludovic Croxford & Peter Brown & Roger G. Pertwee & John W. Huffman & Lorna Layward - 87-91 Light acts directly on organs and cells in culture to set the vertebrate circadian clock
by David Whitmore & Nicholas S. Foulkes & Paolo Sassone-Corsi - 91-94 Delayed activation of the paternal genome during seed development
by Jean-Philippe Vielle-Calzada & Ramamurthy Baskar & Ueli Grossniklaus - 95-99 Eomesodermin is required for mouse trophoblast development and mesoderm formation
by Andreas P. Russ & Sigrid Wattler & William H. Colledge & Samuel A. J. R. Aparicio & Mark B. L. Carlton & Jonathan J. Pearce & Sheila C. Barton & M. Azim Surani & Kenneth Ryan & Michael C. Nehls & Valerie Wilson & Martin J. Evans - 99-103 p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours
by Annie Yang & Nancy Walker & Roderick Bronson & Mourad Kaghad & Mariette Oosterwegel & Jacques Bonnin & Christine Vagner & Helene Bonnet & Pieter Dikkes & Arlene Sharpe & Frank McKeon & Daniel Caput - 103-106 Single-molecule studies of the effect of template tension on T7 DNA polymerase activity
by Gijs J.L. Wuite & Steven B. Smith & Mark Young & David Keller & Carlos Bustamante
February 2000, Volume 403, Issue 6772
- 815-815 Eros begins to yield up its secrets
by Tony Reichhardt - 815-816 Celera in talks to launch private sector human proteome project
by Declan Butler - 816-816 Australian industry ‘starving’ R&D
by Peter Pockley - 816-816 Biomedical centre memorial to victims of Nazi research
by Patrick Weydt - 817-817 Merck blocks ‘safer’ gene therapy trials
by Paul Smaglik - 817-817 Celera's shotgun approach puts Drosophila in the bag
by Natasha Loder - 818-818 Med school to relax rules on business links?
by Steve Nadis - 818-818 Spanish boost for young scientists
by Xavier Bosch - 819-819 AAAS members fret over links with theological foundation
by Colin Macilwain - 819-820 Japan set to tighten ethics rules for genetic sampling
by Robert Triendl - 820-820 Gene therapy institute denies that errors led to trial death
by Paul Smaglik - 820-820 US physics society puts feisty newsletter in doubt
by Colin Macilwain - 821-821 Germany holds up cultivation of GM maize…
by Alison Abbott - 821-821 … amid calls for international biotech panel
by David Dickson - 825-825 Open annotation offers a democratic solution to genome sequencing
by Tim Hubbard & Ewan Birney - 825-825 Affirmative action won't solve sex discrimination
by G.A. Lozano - 825-826 Why Roche deserves the disputed Taq patent
by T. J. White - 826-826 … and there's no proof of lasting brain damage
by Richard Abrams - 826-826 Shrinking shrews
by D.W. Yalden - 826-826 Cloning shock: was Dolly a three-legged accident?
by Wendy Gibson - 826-826 ECT has proved effective in treating depression…
by Max Fink - 827-828 A picaresque genius
by Gunther S. Stent - 828-829 Enter the cosmic cathedral
by P. M. Solomon - 829-830 India's fruitful tryst with technology
by V.S. Arunachalam - 830-830 Science in culture
by Douglas Palmer - 831-831 Fighting the wrong battle
by Geoffrey Cantor - 833-833 Avatars in space
by Geoffrey A. Landis - 835-836 Proteomics for the pore
by Günter Blobel & Richard W. Wozniak - 836-837 As weird as they come
by Volker Heine - 837-839 Tepid tastes
by Robert A. Frank - 839-840 A shear pathway to the core
by Michael J. Walter - 840-841 A social stigma
by Teh-hui Kao & Andrew G. McCubbin - 841-843 Galaxy formation in action
by Gary Welch - 843-845 Extinction by numbers
by Stuart L. Pimm & Peter Raven - 845-846 Attosecond pulses at last
by Paul Corkum - 846-846 The bulge of Casita
by Tim Lincoln - 846-847 Neurofibromin progress on the fly
by Ronald L. Davis - 847-847 Grinding waste away
by David Jones - 848-848 Paul Sigler (1934–2000)
by Brian W. Matthews - 849-850 The sound of many hands clapping
by Z. Néda & E. Ravasz & Y. Brechet & T. Vicsek & A.-L. Barabási - 850-850 Leptin and diabetes in lipoatrophic mice
by Oksana Gavrilova & Bernice Marcus-Samuels & Lisa R. Leon & Charles Vinson & Marc L. Reitman - 850-851 reply: Leptin and diabetes in lipoatrophic mice
by Iichiro Shimomura & Robert E. Hammer & Shinji Ikemoto & Michael S. Brown & Joseph L. Goldstein - 851-851 Exploitation of gut bacteria in the locust
by Rod J. Dillon & Chris T. Vennard & A. Keith Charnley - 851-852 Recovery of breeding success in wild birds
by Tapio Eeva & Esa Lehikoinen - 853-858 Biodiversity hotspots for conservation priorities
by Norman Myers & Russell A. Mittermeier & Cristina G. Mittermeier & Gustavo A. B. da Fonseca & Jennifer Kent - 859-866 Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
by Steven D. Bruner & Derek P. G. Norman & Gregory L. Verdine - 867-869 Formation of molecular gas in the tidal debris of violent galaxy–galaxy interactions
by Jonathan Braine & Ute Lisenfeld & Pierre-Alain Due & Stéphane Leon - 869-871 Geometric quantum computation using nuclear magnetic resonance
by Jonathan A. Jones & Vlatko Vedral & Artur Ekert & Giuseppe Castagnoli - 871-874 Reduction in the surface energy of liquid interfaces at short length scales
by C. Fradin & A. Braslau & D. Luzet & D. Smilgies & M. Alba & N. Boudet & K. Mecke & J. Daillant - 874-877 Electrically induced structure formation and pattern transfer
by Erik Schäffer & Thomas Thurn-Albrecht & Thomas P. Russell & Ullrich Steiner - 877-880 Variations of Younger Dryas atmospheric radiocarbon explicable without ocean circulation changes
by Tomasz Goslar & Maurice Arnold & Nadine Tisnerat-Laborde & Justyna Czernik & Kazimierz Wiȩckowski - 880-883 A thermodynamic explanation for black smoker temperatures
by Tim Jupp & Adam Schultz - 883-886 An interconnected network of core-forming melts produced by shear deformation
by D. Bruhn & N. Groebner & D. L. Kohlstedt - 886-889 Rapid evolution of reproductive barriers driven by sexual conflict
by Sergey Gavrilets - 889-892 Thermal stimulation of taste
by Alberto Cruz & Barry G. Green - 892-895 Postsaccadic visual references generate presaccadic compression of space
by Markus Lappe & Holger Awater & Bart Krekelberg - 895-898 A neurofibromatosis-1-regulated pathway is required for learning in Drosophila
by Hui-Fu Guo & Jiayuan Tong & Frances Hannan & Lin Luo & Yi Zhong - 898-901 Three distinct and sequential steps in the release of sodium ions by the Na+/K+-ATPase
by Miguel Holmgren & Jonathan Wagg & Francisco Bezanilla & Robert F. Rakowski & Paul De Weer & David C. Gadsby - 901-906 The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
by Brenda J. Reinhart & Frank J. Slack & Michael Basson & Amy E. Pasquinelli & Jill C. Bettinger & Ann E. Rougvie & H. Robert Horvitz & Gary Ruvkun - 906-909 Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
by Michael B. Reed & Kevin J. Saliba & Sonia R. Caruana & Kiaran Kirk & Alan F. Cowman - 909-913 The LIM homeobox gene Lhx9 is essential for mouse gonad formation
by Ohad S. Birk & Delane E. Casiano & Christopher A. Wassif & Tiziana Cogliati & Liping Zhao & Yangu Zhao & Alexander Grinberg & SingPing Huang & Jordan A. Kreidberg & Keith L. Parker & Forbes D. Porter & Heiner Westphal - 913-916 The S receptor kinase determines self-incompatibility in Brassica stigma
by Takeshi Takasaki & Katsunori Hatakeyama & Go Suzuki & Masao Watanabe & Akira Isogai & Kokichi Hinata - 916-921 Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding
by Ketan S. Gajiwala & Hua Chen & Fabrice Cornille & Bernard P. Roques & Walter Reith & Bernard Mach & Stephen K. Burley - 921-923 Structure of a ligand-binding intermediate in wild-type carbonmonoxy myoglobin
by Kelvin Chu & Jaroslav Vojtchovský & Benjamin H. McMahon & Robert M. Sweet & Joel Berendzen & Ilme Schlichting
February 2000, Volume 403, Issue 6771
- 689-689 UK scientists under pressure to please
by Natasha Loder - 689-690 Feathers fly over Chinese fossil bird's legality and authenticity
by Rex Dalton - 690-690 The biggest, wildest fossil market in the west
by Rex Dalton - 691-691 Protein structure groups seek to draft common ground rules
by Paul Smaglik - 691-691 Austrian body pleads for normal contacts despite EU freeze
by Quirin Schiermeier & Patrick Weydt - 692-692 Consortium aims to kick-start TB research
by Declan Butler - 692-692 South African government rejects AZT advice
by Michael Cherry - 693-693 …but Astro-E is yet another Japanese failure
by Robert Triendl - 693-693 Europe's X-ray observatory defies the jinx…
by Alison Abbott - 694-694 Funding crisis for Indian biotech centre
by K. S. Jayaraman - 694-694 Republican candidates clash on fetal tissue in research
by Meredith Wadman - 694-694 Russian presidential favourite pledges support for science
by Carl Levitin - 695-695 Oxford professor faces business link inquiry
by Natasha Loder - 698-698 Reliance on the citation index undermines the study of biodiversity
by Antonio G. Valdecasas & Santiago Castroviejo & Leslie F. Marcus - 698-698 Don't let politics put Diamond at risk
by James H. Naismith - 698-698 X chromosomes forget where they came from
by Anne McLaren - 698-698 Proteomics could be key in battle against malaria
by Virendra K. Bhasin - 699-700 One-stop shop for microarray data
by Alvis Brazma & Alan Robinson & Graham Cameron & Michael Ashburner - 701-702 Balancing ambition and restraint
by Robert W. Cahn - 702-703 Between heavens and cloister
by Brenda Maddox