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Real options reasoning and a new look at the R&D investment strategies of pharmaceutical firms

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Cited by:

  1. Yu, Zhen & Xiao, Yao & Li, Jinpo, 2021. "Firm-level perception of uncertainty and innovation activity: Textual evidence from China's A-share market," Pacific-Basin Finance Journal, Elsevier, vol. 68(C).
  2. Hartmann, Marcus & Hassan, Ali, 2006. "Application of real options analysis for pharmaceutical R&D project valuation--Empirical results from a survey," Research Policy, Elsevier, vol. 35(3), pages 343-354, April.
  3. Nault, Kelly A. & Sezer, Ovul & Klein, Nadav, 2023. "It’s the journey, not just the destination: Conveying interpersonal warmth in written introductions," Organizational Behavior and Human Decision Processes, Elsevier, vol. 177(C).
  4. Dongyoub Shin & Sunhyuk Kim & Kiwon Jung, 2016. "Intended rationality in exit decisions: The organizational field of rivals as a source of signal in segment exit decisions by Korean SI ventures, 2000–2006," Australian Journal of Management, Australian School of Business, vol. 41(2), pages 398-421, May.
  5. Suk Choi & Christopher Williams, 2014. "The impact of innovation intensity, scope, and spillovers on sales growth in Chinese firms," Asia Pacific Journal of Management, Springer, vol. 31(1), pages 25-46, March.
  6. Estrada, Isabel & de la Fuente, Gabriel & Martín-Cruz, Natalia, 2010. "Technological joint venture formation under the real options approach," Research Policy, Elsevier, vol. 39(9), pages 1185-1197, November.
  7. Han T. J. Smit & Lenos Trigeorgis, 2017. "Strategic NPV: Real Options and Strategic Games under Different Information Structures," Strategic Management Journal, Wiley Blackwell, vol. 38(13), pages 2555-2578, December.
  8. Jeffrey J. Reuer & Tony W. Tong, 2007. "Corporate investments and growth options," Managerial and Decision Economics, John Wiley & Sons, Ltd., vol. 28(8), pages 863-877.
  9. Sam Ransbotham & Sabyasachi Mitra, 2010. "Target Age and the Acquisition of Innovation in High-Technology Industries," Management Science, INFORMS, vol. 56(11), pages 2076-2093, November.
  10. Song, Sangcheol, 2023. "Multinational operational flexibility, within-network redundancy, and downside risks and divestment rates of international investments," International Business Review, Elsevier, vol. 32(1).
  11. Galloway, Tera L. & Miller, Douglas R. & Sahaym, Arvin & Arthurs, Jonathan D., 2017. "Exploring the innovation strategies of young firms: Corporate venture capital and venture capital impact on alliance innovation strategy," Journal of Business Research, Elsevier, vol. 71(C), pages 55-65.
  12. Chen, Yinghui, 2021. "Does political turnover stifle or stimulate corporate innovation?," International Review of Economics & Finance, Elsevier, vol. 76(C), pages 1126-1145.
  13. Liu, Yaosong & Zhang, Min & Ye, Tingting & Zhang, Yue, 2019. "Does giving always lead to getting? Evidence from the collapse of charity credibility in China," Pacific-Basin Finance Journal, Elsevier, vol. 58(C).
  14. Jinwan Cho & Eunmi Kim & Insik Jeong, 2023. "Adoption of the 4th Industrial Revolution: evidence from Korean exporters in international markets," Asian Business & Management, Palgrave Macmillan, vol. 22(1), pages 164-187, February.
  15. Rose.Janna L. & Quave, Cassandra L. & Islam, Gazi, 2011. "The Four-Sided Triangle of Ethics in Bioprospecting: Pharmaceutical Business, International Politics, Socio-Environmental Responsibility and the Importance of Local Stakeholders," Insper Working Papers wpe_267, Insper Working Paper, Insper Instituto de Ensino e Pesquisa.
  16. Wang, Tao, 2023. "Toward an understanding of innovation failure: The timing of failure experience," Technovation, Elsevier, vol. 125(C).
  17. John C. Eklund, 2022. "The knowledge‐incentive tradeoff: Understanding the relationship between research and development decentralization and innovation," Strategic Management Journal, Wiley Blackwell, vol. 43(12), pages 2478-2509, December.
  18. D׳Souza, Derrick E. & Kulkarni, Shailesh S., 2015. "A framework and model for absorptive capacity in a dynamic multi-firm environment," International Journal of Production Economics, Elsevier, vol. 167(C), pages 50-62.
  19. Van De Vrande, Vareska & Subramanian, Annapoornima M. & Lévesque, Moren & Klopf, Patricia, 2024. "The interdependent influence of lobbying and intellectual capital on new drug development," Research Policy, Elsevier, vol. 53(2).
  20. Simon J. D. Schillebeeckx & Sankalp Chaturvedi & Gerard George & Zella King, 2016. "What do i want? The effects of individual aspiration and relational capability on collaboration preferences," Strategic Management Journal, Wiley Blackwell, vol. 37(7), pages 1493-1506, July.
  21. Raisa Pérez-Vas & Félix Puime Guillén & Joaquín Enríquez-Díaz, 2021. "Valuation of a Company Producing and Trading Seaweed for Human Consumption: Classical Methods vs. Real Options," IJERPH, MDPI, vol. 18(10), pages 1-13, May.
  22. Fatima Shuwaikh & Mathew Hughes & Souad Brinette & Sabrina Khemiri, 2024. "Investment decisions under uncertainty: Corporate venture capital as a real option," International Journal of Finance & Economics, John Wiley & Sons, Ltd., vol. 29(2), pages 2452-2471, April.
  23. Andrea Fosfuri & Marco S. Giarratana & Alessandra Luzzi, 2005. "Firm Assets and Investments in Open Source Software Products," DRUID Working Papers 05-10, DRUID, Copenhagen Business School, Department of Industrial Economics and Strategy/Aalborg University, Department of Business Studies.
  24. Marc Fréchet & Hassen Raîs, 2015. "Les managers raisonnent-ils par options réelles ? Une étude exploratoire des déterminants," Post-Print hal-01764120, HAL.
  25. Fisch, Jan Hendrik, 2008. "Internalization and internationalization under competing real options," Journal of International Management, Elsevier, vol. 14(2), pages 108-123, June.
  26. Tony W. Tong & Yong Li, 2011. "Real Options and Investment Mode: Evidence from Corporate Venture Capital and Acquisition," Organization Science, INFORMS, vol. 22(3), pages 659-674, June.
  27. Kyeungrae Oh, 2017. "MNEs’ Ownership Structure under Uncertainty: Explanations from TCE and Real Options Logic," International Journal of Business and Management, Canadian Center of Science and Education, vol. 12(2), pages 1-67, January.
  28. Lu, Chao & Yang, Meng & Xia, Xiaoxue, 2023. "Economic policy uncertainty and default risk: Evidence from China," Economic Analysis and Policy, Elsevier, vol. 79(C), pages 821-836.
  29. Keith D. Brouthers & Desislava Dikova, 2010. "Acquisitions and Real Options: The Greenfield Alternative," Journal of Management Studies, Wiley Blackwell, vol. 47(6), pages 1048-1071, September.
  30. Alejandro Mac Cawley & Maximiliano Cubillos & Rodrigo Pascual, 2020. "A real options approach for joint overhaul and replacement strategies with mean reverting prices," Annals of Operations Research, Springer, vol. 286(1), pages 303-324, March.
  31. Yang, Hongyan & Steensma, H. Kevin, 2014. "When do firms rely on their knowledge spillover recipients for guidance in exploring unfamiliar knowledge?," Research Policy, Elsevier, vol. 43(9), pages 1496-1507.
  32. Wu, Jianfeng & Shanley, Mark T., 2009. "Knowledge stock, exploration, and innovation: Research on the United States electromedical device industry," Journal of Business Research, Elsevier, vol. 62(4), pages 474-483, April.
  33. Ahlers, Oliver & Hack, Andreas & Kellermanns, Franz W., 2014. "“Stepping into the buyers’ shoes”: Looking at the value of family firms through the eyes of private equity investors," Journal of Family Business Strategy, Elsevier, vol. 5(4), pages 384-396.
  34. Baron, Justus & Pohlmann, Tim & Blind, Knut, 2016. "Essential patents and standard dynamics," Research Policy, Elsevier, vol. 45(9), pages 1762-1773.
  35. Philip Bromiley & Devaki Rau & Yu Zhang, 2017. "Is R&D risky?," Strategic Management Journal, Wiley Blackwell, vol. 38(4), pages 876-891, April.
  36. Li, Yong & Mahoney, Joseph T., 2011. "When are venture capital projects initiated?," Journal of Business Venturing, Elsevier, vol. 26(2), pages 239-254, March.
  37. Pooja Thakur-Wernz & Olga Bruyaka, 2017. "Co-evolutionary Perspective on Sourcing Portfolios: Examining Sourcing Choices for Clinical Trials of Bio-pharmaceutical Firms," Management International Review, Springer, vol. 57(6), pages 909-946, December.
  38. Joon Mahn Lee & Jung Chul Park & Timothy B. Folta, 2018. "CEO career horizon, corporate governance, and real options: The role of economic short‐termism," Strategic Management Journal, Wiley Blackwell, vol. 39(10), pages 2703-2725, October.
  39. Andries, Petra & Hünermund, Paul, 2020. "Firm-level effects of staged investments in innovation: The moderating role of resource availability," Research Policy, Elsevier, vol. 49(7).
  40. Juan Alberto Aragon‐Correa & Dante I. Leyva‐de la Hiz, 2016. "The Influence of Technology Differences on Corporate Environmental Patents: A Resource‐Based Versus an Institutional View of Green Innovations," Business Strategy and the Environment, Wiley Blackwell, vol. 25(6), pages 421-434, September.
  41. René Belderbos & Tony W. Tong & Shubin Wu, 2020. "Portfolio configuration and foreign entry decisions: A juxtaposition of real options and risk diversification theories," Strategic Management Journal, Wiley Blackwell, vol. 41(7), pages 1191-1209, July.
  42. Li, Yong & James, Barclay & Madhavan, Ravi & Mahoney, Joseph T., 2006. "Real Options: Taking Stock and Looking Ahead," Working Papers 06-0114, University of Illinois at Urbana-Champaign, College of Business.
  43. Zhang, Min & Liu, Yaosong & Xie, Lu & Ye, Tingting, 2017. "Does the cutoff of “red capital” raise a red flag? Political connections and stock price crash risk," The North American Journal of Economics and Finance, Elsevier, vol. 39(C), pages 89-109.
  44. Jeffrey J. Reuer & Tony W. Tong, 2010. "Discovering Valuable Growth Opportunities: An Analysis of Equity Alliances with IPO Firms," Organization Science, INFORMS, vol. 21(1), pages 202-215, February.
  45. Sahaym, Arvin & Treviño, Len J. & Steensma, H. Kevin, 2012. "The influence of managerial discretion, innovation and uncertainty on export intensity: A real options perspective," International Business Review, Elsevier, vol. 21(6), pages 1131-1147.
  46. Mitchell, J. Robert & Shepherd, Dean A., 2010. "To thine own self be true: Images of self, images of opportunity, and entrepreneurial action," Journal of Business Venturing, Elsevier, vol. 25(1), pages 138-154, January.
  47. Xue Yang & Yuandi Wang & Die Hu & Yongqiang Gao, 2018. "How industry peers improve your sustainable development? The role of listed firms in environmental strategies," Business Strategy and the Environment, Wiley Blackwell, vol. 27(8), pages 1313-1333, December.
  48. Carlo Corradini & Pelin Demirel & Giuliana Battisti, 2016. "Technological diversification within UK’s small serial innovators," Small Business Economics, Springer, vol. 47(1), pages 163-177, June.
  49. Carol Alexander & Xi Chen, 2021. "Model risk in real option valuation," Annals of Operations Research, Springer, vol. 299(1), pages 1025-1056, April.
  50. Fisch, Christian & Meoli, Michele & Vismara, Silvio & Block, Jörn H., 2022. "The effect of trademark breadth on IPO valuation and post-IPO performance: an empirical investigation of 1510 European IPOs," Journal of Business Venturing, Elsevier, vol. 37(5).
  51. Ma, Xuejiao & Che, Tianqi & Sun, Xiaohua, 2024. "A carbon information disclosure perspective on carbon premium: Evidence from China," Journal of Business Research, Elsevier, vol. 173(C).
  52. Simeth, Markus & Lhuillery, Stephane, 2015. "How do firms develop capabilities for scientific disclosure?," Research Policy, Elsevier, vol. 44(7), pages 1283-1295.
  53. Aabo, Tom & Pantzalis, Christos & Park, Jung Chul, 2016. "Multinationality as real option facilitator — Illusion or reality?," Journal of Corporate Finance, Elsevier, vol. 38(C), pages 1-17.
  54. Puay Khoon Toh & Shiva Agarwal, 2023. "The option value in complements within platform‐based ecosystems," Strategic Management Journal, Wiley Blackwell, vol. 44(2), pages 576-609, February.
  55. Bing Guo & Jing Wang & Steven X. Wei, 2018. "R&D spending, strategic position and firm performance," Frontiers of Business Research in China, Springer, vol. 12(1), pages 1-19, December.
  56. Driouchi, Tarik & Bennett, David, 2011. "Real options in multinational decision-making: Managerial awareness and risk implications," Journal of World Business, Elsevier, vol. 46(2), pages 205-219, April.
  57. Lee, Junghoon, 2016. "The impact of idiosyncratic uncertainty when investment opportunities are endogenous," Journal of Economic Dynamics and Control, Elsevier, vol. 65(C), pages 105-124.
  58. Taj, Saud A., 2016. "Application of signaling theory in management research: Addressing major gaps in theory," European Management Journal, Elsevier, vol. 34(4), pages 338-348.
  59. Engelen, Peter-Jan & Kool, Clemens & Li, Ye, 2016. "A barrier options approach to modeling project failure: The case of hydrogen fuel infrastructure," Resource and Energy Economics, Elsevier, vol. 43(C), pages 33-56.
  60. Zhang, Gupeng & Xiong, Libin & Duan, Hongbo & Huang, Dujuan, 2020. "Obtaining certainty vs. creating uncertainty: Does firms’ patent filing strategy work as expected?," Technological Forecasting and Social Change, Elsevier, vol. 160(C).
  61. Peeters, T.J.G., 2013. "External knowledge search and use in new product development," Other publications TiSEM 300ebb34-b090-4210-b95e-f, Tilburg University, School of Economics and Management.
  62. Aghaie, Sina & Javadinia, Amir & Mirahmad, Hooman & Janani, Saeed, 2022. "How incumbents’ response strategy impacts rivals’ market exit timing?," Journal of Business Research, Elsevier, vol. 146(C), pages 251-263.
  63. Attah-Boakye, Rexford & Adams, Kweku & Hernandez-Perdomo, Elvis & Yu, Honglan & Johansson, Jeaneth, 2023. "Resource re-orchestration and firm survival in crisis periods: The role of business models of technology MNEs during COVID-19," Technovation, Elsevier, vol. 125(C).
  64. Patrice Bouvet & Flora Sfez, 2023. "The transfers of football players: an optional analysis [Le transfert des joueurs de football : une analyse optionnelle]," Post-Print hal-04603890, HAL.
  65. Malik, Tariq, 2012. "Disparate association between alliance social capital and the global pharmaceutical firm's performance," International Business Review, Elsevier, vol. 21(6), pages 1017-1028.
  66. Hunt, Richard A. & Song, Yue & Townsend, David M. & Stallkamp, Maximilian, 2021. "Internationalization of entrepreneurial firms: Leveraging real options reasoning through affordable loss logics," Journal of Business Research, Elsevier, vol. 133(C), pages 194-207.
  67. Huang, Yuanyuan & Xie, En & Wu, Zhan, 2021. "Portfolio characteristics of outward foreign direct investment and dynamic performance of emerging economy firms: An option portfolio perspective," International Business Review, Elsevier, vol. 30(4).
  68. Rammer, Christian, 2012. "Schwerpunktbericht zur Innovationserhebung 2010: Management von Innovationsprojekten - Auswirkungen der Wirtschaftskrise," ZEW Dokumentationen 12-03, ZEW - Leibniz Centre for European Economic Research.
  69. Denicolai, Stefano & Ramirez, Matias & Tidd, Joe, 2016. "Overcoming the false dichotomy between internal R&D and external knowledge acquisition: Absorptive capacity dynamics over time," Technological Forecasting and Social Change, Elsevier, vol. 104(C), pages 57-65.
  70. Pertuze, Julio A. & Reyes, Tomas & Vassolo, Roberto S. & Olivares, Nicolas, 2019. "Political uncertainty and innovation: The relative effects of national leaders’ education levels and regime systems on firm-level patent applications," Research Policy, Elsevier, vol. 48(9), pages 1-1.
  71. Carla Irissarry & Thierry Burger-Helmchen, 2024. "Using Artificial Intelligence to Advance the Research and Development of Orphan Drugs," Businesses, MDPI, vol. 4(3), pages 1-20, September.
  72. Sahaym, Arvin & Steensma, H. Kevin & Barden, Jeffrey Q., 2010. "The influence of R&D investment on the use of corporate venture capital: An industry-level analysis," Journal of Business Venturing, Elsevier, vol. 25(4), pages 376-388, July.
  73. Choi, Young Rok & Zahra, Shaker A. & Yoshikawa, Toru & Han, Bong H., 2015. "Family ownership and R&D investment: The role of growth opportunities and business group membership," Journal of Business Research, Elsevier, vol. 68(5), pages 1053-1061.
  74. Jan Hendrik, Fisch, 2011. "Real call options to enlarge foreign subsidiaries - The moderating effect of irreversibility on the influence of economic volatility and political instability on subsequent FDI," Journal of World Business, Elsevier, vol. 46(4), pages 517-526, October.
  75. Dimitrios Zormpas, 2017. "How vertical relationships and external funding affect investment efficiency and timing?," 2017 Papers pzo81, Job Market Papers.
  76. Wei-Ru Chen, 2008. "Determinants of Firms' Backward- and Forward-Looking R&D Search Behavior," Organization Science, INFORMS, vol. 19(4), pages 609-622, August.
  77. Andrejs Čirjevskis, 2021. "Value Maximizing Decisions in the Real Estate Market: Real Options Valuation Approach," JRFM, MDPI, vol. 14(6), pages 1-19, June.
  78. Kim, Bongsun & Kim, Eonsoo & Miller, Douglas J. & Mahoney, Joseph T., 2016. "The impact of the timing of patents on innovation performance," Research Policy, Elsevier, vol. 45(4), pages 914-928.
  79. Favato, Giampiero & Vecchiato, Riccardo, 2017. "Embedding real options in scenario planning: A new methodological approach," Technological Forecasting and Social Change, Elsevier, vol. 124(C), pages 135-149.
  80. Li, Yong, 2008. "Duration analysis of venture capital staging: A real options perspective," Journal of Business Venturing, Elsevier, vol. 23(5), pages 497-512, September.
  81. Kyungwon Kim & Jae Wook Song, 2018. "Managing Bubbles in the Korean Real Estate Market: A Real Options Framework," Sustainability, MDPI, vol. 10(8), pages 1-25, August.
  82. Han Smit & Enrico Pennings & Sjoerd Bekkum, 2017. "Real options and institutions," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 48(5), pages 620-644, July.
  83. Keith D. Brouthers & Lance Eliot Brouthers & Steve Werner, 2008. "Real Options, International Entry Mode Choice and Performance," Journal of Management Studies, Wiley Blackwell, vol. 45(5), pages 936-960, July.
  84. Wang, Ning & Hagedoorn, John, 2014. "The lag structure of the relationship between patenting and internal R&D revisited," Research Policy, Elsevier, vol. 43(8), pages 1275-1285.
  85. Feng Xu & Xin (Robert) Luo & Hongyun Zhang & Shan Liu & Wei (Wayne) Huang, 2019. "Do Strategy and Timing in IT Security Investments Matter? An Empirical Investigation of the Alignment Effect," Information Systems Frontiers, Springer, vol. 21(5), pages 1069-1083, October.
  86. Xin Li & Qiong Xu & Fei Guo & Hecheng Wang, 2023. "State‐owned equity participation and private sector enterprises' strategic risk taking: Evidence from China," Managerial and Decision Economics, John Wiley & Sons, Ltd., vol. 44(2), pages 1107-1124, March.
  87. Sangcheol Song, 2017. "Ownership Increase in International Joint Ventures: The Within- and Across-Country Flexibility Perspective," Management International Review, Springer, vol. 57(1), pages 93-120, February.
  88. Khoury, Theodore A. & Pleggenkuhle-Miles, Erin G., 2011. "Shared inventions and the evolution of capabilities: Examining the biotechnology industry," Research Policy, Elsevier, vol. 40(7), pages 943-956, September.
  89. Gorupec Natalia & Brehmer Nataliia & Tiberius Victor & Kraus Sascha, 2022. "Tackling uncertain future scenarios with real options: A review and research framework," The Irish Journal of Management, Sciendo, vol. 41(1), pages 69-88, July.
  90. Brau, James C. & Sutton, Ninon K. & Hatch, Nile W., 2010. "Dual-track versus single-track sell-outs: An empirical analysis of competing harvest strategies," Journal of Business Venturing, Elsevier, vol. 25(4), pages 389-402, July.
  91. Jaideep Anand & Raffaele Oriani & Roberto S. Vassolo, 2010. "Alliance Activity as a Dynamic Capability in the Face of a Discontinuous Technological Change," Organization Science, INFORMS, vol. 21(6), pages 1213-1232, December.
  92. Junic Kim & Jaewook Yoo, 2019. "Platform Growth Model: The Four Stages of Growth Model," Sustainability, MDPI, vol. 11(20), pages 1-16, October.
  93. FUJIKAWA Naoto & MOTOHASHI Kazuyuki, 2016. "Absorptive Capacity and External Technology Sourcing: Empirical investigation of vertical and horizontal relationships in the research and development process," Discussion papers 16102, Research Institute of Economy, Trade and Industry (RIETI).
  94. Dimitrios Zormpas, 2021. "Jointly Held Investment Options and Vertical Relationships," Review of Industrial Organization, Springer;The Industrial Organization Society, vol. 58(4), pages 513-530, June.
  95. Pattikawa, L.H., 2006. "Modeling Brand Extension as a Real Option: How Expectation, Competition and Financial Constraints Drive the Timing of Extensions," ERIM Report Series Research in Management ERS-2006-030-STR, Erasmus Research Institute of Management (ERIM), ERIM is the joint research institute of the Rotterdam School of Management, Erasmus University and the Erasmus School of Economics (ESE) at Erasmus University Rotterdam.
  96. Silvia Vernizzi & Andrea Beretta Zanoni & Claudio Zuccolotto, 2021. "Strategy Execution: One Size Does Not Fit All: Evidence from Italian Middle Market," International Journal of Business and Management, Canadian Center of Science and Education, vol. 14(11), pages 1-66, July.
  97. Chaudhuri, Shomesh E. & Lo, Andrew W., 2024. "Financially adaptive clinical trials via option pricing analysis," Journal of Econometrics, Elsevier, vol. 240(2).
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