Practical considerations for optimal designs in clinical dose finding studies
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- K. Strassburger & F. Bretz & H. Finner, 2007. "Ordered Multiple Comparisons with the Best and Their Applications to Dose–Response Studies," Biometrics, The International Biometric Society, vol. 63(4), pages 1143-1151, December.
- Dette, Holger & Pepelyshev, Andrey & Wong, Weng Kee, 2008. "Optimal designs for dose finding experiments in toxicity studies," Technical Reports 2008,09, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
- F. Bretz & J. C. Pinheiro & M. Branson, 2005. "Combining Multiple Comparisons and Modeling Techniques in Dose-Response Studies," Biometrics, The International Biometric Society, vol. 61(3), pages 738-748, September.
- Dette, Holger & Bretz, Frank & Pepelyshev, Andrey & Pinheiro, José, 2008. "Optimal Designs for Dose-Finding Studies," Journal of the American Statistical Association, American Statistical Association, vol. 103(483), pages 1225-1237.
- Miller, Frank & Dette, Holger & Guilbaud, Olivier, 2007. "Optimal designs for estimating the interesting part of a dose-effect curve," Technical Reports 2007,21, Technische Universität Dortmund, Sonderforschungsbereich 475: Komplexitätsreduktion in multivariaten Datenstrukturen.
- Stefanie Biedermann & Holger Dette & Philipp Hoffmann, 2009. "Constrained optimal discrimination designs for Fourier regression models," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 61(1), pages 143-157, March.
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Cited by:
- Jiajing Xu & Guosheng Yin & David Ohlssen & Frank Bretz, 2016. "Bayesian two-stage dose finding for cytostatic agents via model adaptation," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 65(3), pages 465-482, April.
- Holger Dette & Laura Hoyden & Sonja Kuhnt & Kirsten Schorning, 2017. "Optimal designs for thermal spraying," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 66(1), pages 53-72, January.
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Keywords
dose finding; robust designs; model uncertainty; minimum effective dose; dose response; target dose estimation; sample size;All these keywords.
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