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Maternal Genetic Risk for Depression and Child Human Capital

Author

Listed:
  • Menta, Giorgia

    (LISER)

  • Lepinteur, Anthony

    (University of Luxembourg)

  • Clark, Andrew E.

    (Paris School of Economics)

  • Ghislandi, Simone

    (Bocconi University)

  • D'Ambrosio, Conchita

    (University of Luxembourg)

Abstract

We here address the causal relationship between the maternal genetic risk for depression and child human capital using UK birth-cohort data. We find that an increase of one standard deviation (SD) in the maternal polygenic risk score for depression reduces their children's cognitive and non-cognitive skill scores by 5 to 7% of a SD throughout adolescence. Our results are robust to a battery of sensitivity tests addressing, among others, concerns about pleiotropy and dynastic effects. Our Gelbach decomposition analysis suggests that the strongest mediator is genetic nurture (through maternal depression itself), with genetic inheritance playing only a marginal role.

Suggested Citation

  • Menta, Giorgia & Lepinteur, Anthony & Clark, Andrew E. & Ghislandi, Simone & D'Ambrosio, Conchita, 2022. "Maternal Genetic Risk for Depression and Child Human Capital," IZA Discussion Papers 15798, Institute of Labor Economics (IZA).
    • Handle: RePEc:iza:izadps:dp15798
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    1. Jonah B. Gelbach, 2016. "When Do Covariates Matter? And Which Ones, and How Much?," Journal of Labor Economics, University of Chicago Press, vol. 34(2), pages 509-543.
    2. Abdel Abdellaoui & David Hugh-Jones & Loic Yengo & Kathryn E. Kemper & Michel G. Nivard & Laura Veul & Yan Holtz & Brendan P. Zietsch & Timothy M. Frayling & Naomi R. Wray & Jian Yang & Karin J. H. Ve, 2019. "Genetic correlates of social stratification in Great Britain," Nature Human Behaviour, Nature, vol. 3(12), pages 1332-1342, December.
    3. James J. Heckman & Jora Stixrud & Sergio Urzua, 2006. "The Effects of Cognitive and Noncognitive Abilities on Labor Market Outcomes and Social Behavior," Journal of Labor Economics, University of Chicago Press, vol. 24(3), pages 411-482, July.
    4. Clark, Andrew E. & Lepinteur, Anthony, 2019. "The causes and consequences of early-adult unemployment: Evidence from cohort data," Journal of Economic Behavior & Organization, Elsevier, vol. 166(C), pages 107-124.
    5. Souvik Banerjee & Pinka Chatterji & Kajal Lahiri, 2017. "Effects of Psychiatric Disorders on Labor Market Outcomes: A Latent Variable Approach Using Multiple Clinical Indicators," Health Economics, John Wiley & Sons, Ltd., vol. 26(2), pages 184-205, February.
    6. Bubonya, Melisa & Cobb-Clark, Deborah A. & Wooden, Mark, 2017. "Mental health and productivity at work: Does what you do matter?," Labour Economics, Elsevier, vol. 46(C), pages 150-165.
    7. Andrew E. Clark & Conchita D'Ambrosio & Marta Barazzetta, 2021. "Childhood circumstances and young adulthood outcomes: The role of mothers' financial problems," Health Economics, John Wiley & Sons, Ltd., vol. 30(2), pages 342-357, February.
    8. Magnus Johannesson & David I. Laibson & Sarah E. Medland & Michelle N. Meyer & Joseph K. Pickrell & Tõnu Esko & Robert F. Krueger & Jonathan P. Beauchamp & Philipp D. Koellinger & Daniel J. Benjamin &, 2016. "Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses," Post-Print hal-02017373, HAL.
    9. James J. Heckman & John Eric Humphries & Gregory Veramendi, 2018. "Returns to Education: The Causal Effects of Education on Earnings, Health, and Smoking," Journal of Political Economy, University of Chicago Press, vol. 126(S1), pages 197-246.
    10. von Hinke, Stephanie & Davey Smith, George & Lawlor, Debbie A. & Propper, Carol & Windmeijer, Frank, 2016. "Genetic markers as instrumental variables," Journal of Health Economics, Elsevier, vol. 45(C), pages 131-148.
    11. Atkinson, Anthony B., 2015. "Inequality: what can be done?," LSE Research Online Documents on Economics 101810, London School of Economics and Political Science, LSE Library.
    12. Jason Fletcher, 2013. "Adolescent Depression and Adult Labor Market Outcomes," Southern Economic Journal, John Wiley & Sons, vol. 80(1), pages 26-49, July.
    13. Briole, Simon & Le Forner, Hélène & Lepinteur, Anthony, 2020. "Children’s socio-emotional skills: Is there a quantity–quality trade-off?," Labour Economics, Elsevier, vol. 64(C).
    14. Philippe Van Kerm, 2003. "Adaptive kernel density estimation," Stata Journal, StataCorp LP, vol. 3(2), pages 148-156, June.
    15. K. Paige Harden & Philipp D. Koellinger, 2020. "Using genetics for social science," Nature Human Behaviour, Nature, vol. 4(6), pages 567-576, June.
    16. von Hinke, Stephanie & Rice, Nigel & Tominey, Emma, 2022. "Mental health around pregnancy and child development from early childhood to adolescence," Labour Economics, Elsevier, vol. 78(C).
    17. Perry, Cynthia D., 2008. "Does treating maternal depression improve child health management The case of pediatric asthma," Journal of Health Economics, Elsevier, vol. 27(1), pages 157-173, January.
    18. Volodymyr Kuleshov & Jialin Ding & Christopher Vo & Braden Hancock & Alexander Ratner & Yang Li & Christopher Ré & Serafim Batzoglou & Michael Snyder, 2019. "A machine-compiled database of genome-wide association studies," Nature Communications, Nature, vol. 10(1), pages 1-8, December.
    19. Del Bono, Emilia & Kinsler, Josh & Pavan, Ronni, 2020. "Skill Formation and the Trouble with Child Non-Cognitive Skill Measures," IZA Discussion Papers 13713, Institute of Labor Economics (IZA).
    20. Andrew E. Clark & Sarah Flèche & Richard Layard & Powdthavee Nattavudh, 2018. "The Origins of Happiness: The Science of Well-Being over the Life Course," Post-Print halshs-01631510, HAL.
    21. Frederick J. Zimmerman & Wayne Katon, 2005. "Socioeconomic status, depression disparities, and financial strain: what lies behind the income‐depression relationship?," Health Economics, John Wiley & Sons, Ltd., vol. 14(12), pages 1197-1215, December.
    22. repec:nas:journl:v:115:y:2018:p:e4970-e4979 is not listed on IDEAS
    23. Victoria Baranov & Sonia Bhalotra & Pietro Biroli & Joanna Maselko, 2020. "Maternal Depression, Women's Empowerment, and Parental Investment: Evidence from a Randomized Controlled Trial," American Economic Review, American Economic Association, vol. 110(3), pages 824-859, March.
    24. Kiernan, Kathleen E. & Huerta, Maria Carmen, 2008. "Economic deprivation, maternal depression, parenting and children's cognitive and emotional development in early childhood," LSE Research Online Documents on Economics 43720, London School of Economics and Political Science, LSE Library.
    25. Flavio Cunha & James J. Heckman, 2008. "Formulating, Identifying and Estimating the Technology of Cognitive and Noncognitive Skill Formation," Journal of Human Resources, University of Wisconsin Press, vol. 43(4).
    26. Joel Becker & Casper A. P. Burik & Grant Goldman & Nancy Wang & Hariharan Jayashankar & Michael Bennett & Daniel W. Belsky & Richard Karlsson Linnér & Rafael Ahlskog & Aaron Kleinman & David A. Hinds , 2021. "Resource profile and user guide of the Polygenic Index Repository," Nature Human Behaviour, Nature, vol. 5(12), pages 1744-1758, December.
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    1. Dehos, Fabian T. & Paul, Marie & Schäfer, Wiebke & Süß, Karolin, 2024. "Time of Change: Health Effects of Motherhood," IZA Discussion Papers 16942, Institute of Labor Economics (IZA).

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    More about this item

    Keywords

    maternal depression; human capital; ALSPAC;
    All these keywords.

    JEL classification:

    • I14 - Health, Education, and Welfare - - Health - - - Health and Inequality
    • J24 - Labor and Demographic Economics - - Demand and Supply of Labor - - - Human Capital; Skills; Occupational Choice; Labor Productivity

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