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Strategic Considerations for Innovation and Commercialization in the US Biotechnology Sector

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  • Sharmistha Bagchi-Sen

Abstract

This paper examines the importance of alliances as an innovation strategy utilized by US biotechnology firms. In doing so, the role of alliances with universities vis-à-vis alliances with industrial companies is emphasized. The biotechnology sector is dominated by few large and many small firms. The small firms are research focused or technology developers. Several large firms are now integrated biopharmaceutical companies. Very few small firms can survive without strengthening their relationships with universities, biotechnology or pharmaceutical or other large companies. These relationships range from licensing agreements, export--import connections to various forms of alliances for R&D, product development and marketing. Large firms supplement in-house R&D by acquiring research products and/or new technologies from small firms as well as universities. A survey of US biotechnology companies is used to show the emergence of alliance relationships, which continue to highlight university linkages, emphasize connections of biotechnology firms with other biotechnology entrepreneurs, and an ongoing effort to build a synergistic relationship with pharmaceutical or other large companies. Most linkages are not confined to the local area; the main locational attribute is the science base or the labour market.

Suggested Citation

  • Sharmistha Bagchi-Sen, 2006. "Strategic Considerations for Innovation and Commercialization in the US Biotechnology Sector," European Planning Studies, Taylor & Francis Journals, vol. 15(6), pages 753-766, May.
  • Handle: RePEc:taf:eurpls:v:15:y:2006:i:6:p:753-766
    DOI: 10.1080/09654310701214226
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    References listed on IDEAS

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    1. Maryann P. Feldman & Cynthia R. Ronzio, 2001. "Closing the innovative loop: moving from the laboratory to the shop floor in biotechnology manufacturing," Entrepreneurship & Regional Development, Taylor & Francis Journals, vol. 13(1), pages 1-16, January.
    2. Walter Powell & Kenneth Koput & James Bowie & Laurel Smith-Doerr, 2002. "The Spatial Clustering of Science and Capital: Accounting for Biotech Firm-Venture Capital Relationships," Regional Studies, Taylor & Francis Journals, vol. 36(3), pages 291-305.
    3. Lerner, Josh & Shane, Hilary & Tsai, Alexander, 2003. "Do equity financing cycles matter? evidence from biotechnology alliances," Journal of Financial Economics, Elsevier, vol. 67(3), pages 411-446, March.
    4. Sharmistha Bagchi-Sen & Helen Lawton Smith & Linda Hall, 2004. "The US Biotechnology Industry: Industry Dynamics and Policy," Environment and Planning C, , vol. 22(2), pages 199-216, April.
    5. Maryann P. Feldman & Maryellen R. Kelley, 2002. "How States Augment the Capabilities of Technology–Pioneering Firms," Growth and Change, Wiley Blackwell, vol. 33(2), pages 173-195.
    6. Anoop Madhok & Thomas Osegowitsch, 2000. "The International Biotechnology Industry: A Dynamic Capabilities Perspective," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 31(2), pages 325-335, June.
    7. Bronwyn H. Hall & Albert N. Link & John T. Scott, 2003. "Universities as Research Partners," The Review of Economics and Statistics, MIT Press, vol. 85(2), pages 485-491, May.
    8. Steven Casper & Anastasios Karamanos, 2003. "Commercializing Science in Europe: The Cambridge Biotechnology Cluster," European Planning Studies, Taylor & Francis Journals, vol. 11(7), pages 805-822, October.
    9. Weijian Shan & Jaeyong Song, 1997. "Foreign Direct Investment and the Sourcing of Technological Advantage: Evidence from the Biotechnology Industry," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 28(2), pages 267-284, June.
    10. Hagedoorn, John & Link, Albert N. & Vonortas, Nicholas S., 2000. "Research partnerships1," Research Policy, Elsevier, vol. 29(4-5), pages 567-586, April.
    11. David B. Audretsch & Paula E. Stephan, 1999. "Knowledge spillovers in biotechnology: sources and incentives," Journal of Evolutionary Economics, Springer, vol. 9(1), pages 97-107.
    12. Bronwyn H. Hall & Albert N. Link & John T. Scott, 2003. "Universities as Research Partners," The Review of Economics and Statistics, MIT Press, vol. 85(2), pages 485-491, May.
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