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Some operations research methods for analyzing protein sequences and structures

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  • Piotr Łukasiak
  • Jacek Błażewicz
  • Maciej Miłostan

Abstract

The operations research is probably one of the most successful field of applied mathematics used in economics, physics, chemistry, almost everywhere where one has to analyze huge amounts of data. Lately, these techniques of operations research were introduced in biology, especially in the protein analysis area to support biologists. The fast growth of protein data makes operations research an important issue in bioinformatics, a science which lays on the border between computer science and biology. This paper gives a short overview of the operations research techniques currently used to support structural and functional analysis of proteins. Copyright Springer Science+Business Media, LLC 2010

Suggested Citation

  • Piotr Łukasiak & Jacek Błażewicz & Maciej Miłostan, 2010. "Some operations research methods for analyzing protein sequences and structures," Annals of Operations Research, Springer, vol. 175(1), pages 9-35, March.
    • Handle: RePEc:spr:annopr:v:175:y:2010:i:1:p:9-35:10.1007/s10479-009-0652-y
    DOI: 10.1007/s10479-009-0652-y
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    References listed on IDEAS

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    5. Dawn M. Strickland & Earl Barnes & Joel S. Sokol, 2005. "Optimal Protein Structure Alignment Using Maximum Cliques," Operations Research, INFORMS, vol. 53(3), pages 389-402, June.
    6. Jonathan P. K. Doye & Robert H. Leary & Marco Locatelli & Fabio Schoen, 2004. "Global Optimization of Morse Clusters by Potential Energy Transformations," INFORMS Journal on Computing, INFORMS, vol. 16(4), pages 371-379, November.
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    Cited by:

    1. Blazewicz, Jacek & Burke, Edmund K. & Kasprzak, Marta & Kovalev, Alexandr & Kovalyov, Mikhail Y., 2011. "The simplified partial digest problem: Approximation and a graph-theoretic model," European Journal of Operational Research, Elsevier, vol. 208(2), pages 142-152, January.

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