IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0140300.html
   My bibliography  Save this article

Investigating the Temporal Patterns within and between Intrinsic Connectivity Networks under Eyes-Open and Eyes-Closed Resting States: A Dynamical Functional Connectivity Study Based on Phase Synchronization

Author

Listed:
  • Xun-Heng Wang
  • Lihua Li
  • Tao Xu
  • Zhongxiang Ding

Abstract

The brain active patterns were organized differently under resting states of eyes open (EO) and eyes closed (EC). The altered voxel-wise and regional-wise resting state active patterns under EO/EC were found by static analysis. More importantly, dynamical spontaneous functional connectivity has been observed in the resting brain. To the best of our knowledge, the dynamical mechanisms of intrinsic connectivity networks (ICNs) under EO/EC remain largely unexplored. The goals of this paper were twofold: 1) investigating the dynamical intra-ICN and inter-ICN temporal patterns during resting state; 2) analyzing the altered dynamical temporal patterns of ICNs under EO/EC. To this end, a cohort of healthy subjects with scan conditions of EO/EC were recruited from 1000 Functional Connectomes Project. Through Hilbert transform, time-varying phase synchronization (PS) was applied to evaluate the inter-ICN synchrony. Meanwhile, time-varying amplitude was analyzed as dynamical intra-ICN temporal patterns. The results found six micro-states of inter-ICN synchrony. The medial visual network (MVN) showed decreased intra-ICN amplitude during EC relative to EO. The sensory-motor network (SMN) and auditory network (AN) exhibited enhanced intra-ICN amplitude during EC relative to EO. Altered inter-ICN PS was found between certain ICNs. Particularly, the SMN and AN exhibited enhanced PS to other ICNs during EC relative to EO. In addition, the intra-ICN amplitude might influence the inter-ICN synchrony. Moreover, default mode network (DMN) might play an important role in information processing during EO/EC. Together, the dynamical temporal patterns within and between ICNs were altered during different scan conditions of EO/EC. Overall, the dynamical intra-ICN and inter-ICN temporal patterns could benefit resting state fMRI-related research, and could be potential biomarkers for human functional connectome.

Suggested Citation

  • Xun-Heng Wang & Lihua Li & Tao Xu & Zhongxiang Ding, 2015. "Investigating the Temporal Patterns within and between Intrinsic Connectivity Networks under Eyes-Open and Eyes-Closed Resting States: A Dynamical Functional Connectivity Study Based on Phase Synchron," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-20, October.
    • Handle: RePEc:plo:pone00:0140300
    DOI: 10.1371/journal.pone.0140300
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140300
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0140300&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0140300?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Birk Diedenhofen & Jochen Musch, 2015. "cocor: A Comprehensive Solution for the Statistical Comparison of Correlations," PLOS ONE, Public Library of Science, vol. 10(4), pages 1-12, April.
    2. Chris Fraley & Adrian E. Raftery, 2003. "Enhanced Model-Based Clustering, Density Estimation, and Discriminant Analysis Software: MCLUST," Journal of Classification, Springer;The Classification Society, vol. 20(2), pages 263-286, September.
    3. Chaogan Yan & Dongqiang Liu & Yong He & Qihong Zou & Chaozhe Zhu & Xinian Zuo & Xiangyu Long & Yufeng Zang, 2009. "Spontaneous Brain Activity in the Default Mode Network Is Sensitive to Different Resting-State Conditions with Limited Cognitive Load," PLOS ONE, Public Library of Science, vol. 4(5), pages 1-11, May.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Mark S. Handcock & Adrian E. Raftery & Jeremy M. Tantrum, 2007. "Model‐based clustering for social networks," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 170(2), pages 301-354, March.
    2. repec:jss:jstsof:14:i12 is not listed on IDEAS
    3. Anthony Evans & Willem Sleegers & Žan Mlakar, 2020. "Individual differences in receptivity to scientific bullshit," Judgment and Decision Making, Society for Judgment and Decision Making, vol. 15(3), pages 401-412, May.
    4. Walters, William H., 2017. "Do subjective journal ratings represent whole journals or typical articles? Unweighted or weighted citation impact?," Journal of Informetrics, Elsevier, vol. 11(3), pages 730-744.
    5. Maugis, C. & Celeux, G. & Martin-Magniette, M.-L., 2011. "Variable selection in model-based discriminant analysis," Journal of Multivariate Analysis, Elsevier, vol. 102(10), pages 1374-1387, November.
    6. Cathy Maugis & Gilles Celeux & Marie-Laure Martin-Magniette, 2009. "Variable Selection for Clustering with Gaussian Mixture Models," Biometrics, The International Biometric Society, vol. 65(3), pages 701-709, September.
    7. Jeffrey Andrews & Paul McNicholas, 2014. "Variable Selection for Clustering and Classification," Journal of Classification, Springer;The Classification Society, vol. 31(2), pages 136-153, July.
    8. Kathrin Leppek & Gun Woo Byeon & Wipapat Kladwang & Hannah K. Wayment-Steele & Craig H. Kerr & Adele F. Xu & Do Soon Kim & Ved V. Topkar & Christian Choe & Daphna Rothschild & Gerald C. Tiu & Roger We, 2022. "Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics," Nature Communications, Nature, vol. 13(1), pages 1-22, December.
    9. Kevin Handtke & Lisa Richter-Beuschel & Susanne Bögeholz, 2022. "Self-Efficacy Beliefs of Teaching ESD: A Theory-Driven Instrument and the Effectiveness of ESD in German Teacher Education," Sustainability, MDPI, vol. 14(11), pages 1-32, May.
    10. repec:jss:jstsof:18:i06 is not listed on IDEAS
    11. repec:cup:judgdm:v:15:y:2020:i:2:p:193-202 is not listed on IDEAS
    12. Zhang, Ping & Serban, Nicoleta, 2007. "Discovery, visualization and performance analysis of enterprise workflow," Computational Statistics & Data Analysis, Elsevier, vol. 51(5), pages 2670-2687, February.
    13. Hennig, Christian, 2008. "Dissolution point and isolation robustness: Robustness criteria for general cluster analysis methods," Journal of Multivariate Analysis, Elsevier, vol. 99(6), pages 1154-1176, July.
    14. Alan E. Stewart & Harrison E. Chapman & Jackson B. L. Davis, 2023. "Anxiety and Worry about Six Categories of Climate Change Impacts," IJERPH, MDPI, vol. 21(1), pages 1-24, December.
    15. Dang,Hai-Anh H. & Pullinger,John James & Serajuddin,Umar & Stacy,Brian William, 2024. "Reviewing Assessment Tools for Measuring Country Statistical Capacity," Policy Research Working Paper Series 10717, The World Bank.
    16. Hornik, Kurt, 2005. "A CLUE for CLUster Ensembles," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 14(i12).
    17. Kristina M. Garske & Asha Kar & Caroline Comenho & Brunilda Balliu & David Z. Pan & Yash V. Bhagat & Gregory Rosenberg & Amogha Koka & Sankha Subhra Das & Zong Miao & Janet S. Sinsheimer & Jaakko Kapr, 2023. "Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    18. Salter-Townshend, Michael & Murphy, Thomas Brendan, 2013. "Variational Bayesian inference for the Latent Position Cluster Model for network data," Computational Statistics & Data Analysis, Elsevier, vol. 57(1), pages 661-671.
    19. Maike Stolz & Christian Albus & Manfred E. Beutel & Hans-Christian Deter & Kurt Fritzsche & Christoph Herrmann-Lingen & Matthias Michal & Katja Petrowski & Joram Ronel & Jobst-Hendrik Schultz & Wolfga, 2023. "Assessment of health-related quality of life in individuals with depressive symptoms: validity and responsiveness of the EQ-5D-3L and the SF-6D," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(8), pages 1297-1307, November.
    20. Les Sikos & Noortje J Venhuizen & Heiner Drenhaus & Matthew W Crocker, 2021. "Reevaluating pragmatic reasoning in language games," PLOS ONE, Public Library of Science, vol. 16(3), pages 1-33, March.
    21. Kay, Adam A. & Skarlicki, Daniel P., 2020. "Cultivating a conflict-positive workplace: How mindfulness facilitates constructive conflict management," Organizational Behavior and Human Decision Processes, Elsevier, vol. 159(C), pages 8-20.
    22. McNicholas, P.D. & Murphy, T.B. & McDaid, A.F. & Frost, D., 2010. "Serial and parallel implementations of model-based clustering via parsimonious Gaussian mixture models," Computational Statistics & Data Analysis, Elsevier, vol. 54(3), pages 711-723, March.
    23. repec:cup:judgdm:v:15:y:2020:i:3:p:401-412 is not listed on IDEAS
    24. Wenke, Kathrin & Zapkau, Florian B. & Schwens, Christian, 2021. "Too small to do it all? A meta-analysis on the relative relationships of exploration, exploitation, and ambidexterity with SME performance," Journal of Business Research, Elsevier, vol. 132(C), pages 653-665.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0140300. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.