Unsupervised Clustering of Subcellular Protein Expression Patterns in High-Throughput Microscopy Images Reveals Protein Complexes and Functional Relationships between Proteins
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DOI: 10.1371/journal.pcbi.1003085
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- Lior Shamir & John D Delaney & Nikita Orlov & D Mark Eckley & Ilya G Goldberg, 2010. "Pattern Recognition Software and Techniques for Biological Image Analysis," PLOS Computational Biology, Public Library of Science, vol. 6(11), pages 1-10, November.
- John R. S. Newman & Sina Ghaemmaghami & Jan Ihmels & David K. Breslow & Matthew Noble & Joseph L. DeRisi & Jonathan S. Weissman, 2006. "Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise," Nature, Nature, vol. 441(7095), pages 840-846, June.
- Won-Ki Huh & James V. Falvo & Luke C. Gerke & Adam S. Carroll & Russell W. Howson & Jonathan S. Weissman & Erin K. O'Shea, 2003. "Global analysis of protein localization in budding yeast," Nature, Nature, vol. 425(6959), pages 686-691, October.
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- Lit-Hsin Loo & Danai Laksameethanasan & Yi-Ling Tung, 2014. "Quantitative Protein Localization Signatures Reveal an Association between Spatial and Functional Divergences of Proteins," PLOS Computational Biology, Public Library of Science, vol. 10(3), pages 1-17, March.
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