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A revolution in optical manipulation

Author

Listed:
  • David G. Grier

    (James Franck Institute and Institute for Biophysical Dynamics, The University of Chicago)

Abstract

Optical tweezers use the forces exerted by a strongly focused beam of light to trap and move objects ranging in size from tens of nanometres to tens of micrometres. Since their introduction in 1986, the optical tweezer has become an important tool for research in the fields of biology, physical chemistry and soft condensed matter physics. Recent advances promise to take optical tweezers out of the laboratory and into the mainstream of manufacturing and diagnostics; they may even become consumer products. The next generation of single-beam optical traps offers revolutionary new opportunities for fundamental and applied research.

Suggested Citation

  • David G. Grier, 2003. "A revolution in optical manipulation," Nature, Nature, vol. 424(6950), pages 810-816, August.
    • Handle: RePEc:nat:nature:v:424:y:2003:i:6950:d:10.1038_nature01935
    DOI: 10.1038/nature01935
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    Cited by:

    1. Wu, You & He, Shangling & Wu, Jinhong & Lin, Zejia & Chen, Libang & Qiu, Huixin & Liu, Yujun & Hong, Shihan & Chen, Kaihui & Fu, Xinming & Xu, Chuangjie & He, Yingji & Deng, Dongmei, 2021. "Autofocusing Pearcey-like vortex beam along a parabolic trajectory," Chaos, Solitons & Fractals, Elsevier, vol. 145(C).
    2. Li Liu & Ying Fang & Qingsheng Huang & Jianhua Wu, 2011. "A Rigidity-Enhanced Antimicrobial Activity: A Case for Linear Cationic α-Helical Peptide HP(2–20) and Its Four Analogues," PLOS ONE, Public Library of Science, vol. 6(1), pages 1-8, January.
    3. Wei Chen & Wang Zhang & Yuan Liu & Fan-Chao Meng & John M. Dudley & Yan-Qing Lu, 2022. "Time diffraction-free transverse orbital angular momentum beams," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    4. Chih-Hao Huang & Boris Louis & Roger Bresolí-Obach & Tetsuhiro Kudo & Rafael Camacho & Ivan G. Scheblykin & Teruki Sugiyama & Johan Hofkens & Hiroshi Masuhara, 2022. "The primeval optical evolving matter by optical binding inside and outside the photon beam," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    5. Qingqiao Xie & Yuandi Zhuang & Gaojun Ye & Tiankuo Wang & Yi Cao & Lingxiang Jiang, 2021. "Astral hydrogels mimic tissue mechanics by aster-aster interpenetration," Nature Communications, Nature, vol. 12(1), pages 1-9, December.
    6. Chenhao Li & Torsten Wieduwilt & Fedja J. Wendisch & Andrés Márquez & Leonardo de S. Menezes & Stefan A. Maier & Markus A. Schmidt & Haoran Ren, 2023. "Metafiber transforming arbitrarily structured light," Nature Communications, Nature, vol. 14(1), pages 1-10, December.
    7. Fan Nan & Francisco J. Rodríguez-Fortuño & Shaohui Yan & Jack J. Kingsley-Smith & Jack Ng & Baoli Yao & Zijie Yan & Xiaohao Xu, 2023. "Creating tunable lateral optical forces through multipolar interplay in single nanowires," Nature Communications, Nature, vol. 14(1), pages 1-9, December.
    8. Ahmed H. Dorrah & Noah A. Rubin & Michele Tamagnone & Aun Zaidi & Federico Capasso, 2021. "Structuring total angular momentum of light along the propagation direction with polarization-controlled meta-optics," Nature Communications, Nature, vol. 12(1), pages 1-13, December.
    9. Zhang, Haonan & Duan, Buren & Wu, Lizhi & Hua, Zuohao & Bao, Zijing & Guo, Ning & Ye, Yinghua & Galfetti, Luciano & DeLuca, Luigi T. & Shen, Ruiqi, 2021. "Actualization of an efficient throttleable laser propulsion mode," Energy, Elsevier, vol. 221(C).
    10. Djoko, M. & Tabi, Conrad Bertrand & Kofane, T.C., 2021. "Effects of the septic nonlinearity and the initial value of the radius of orbital angular momentum beams on data transmission in optical fibers using the cubic-quintic-septic complex Ginzburg-Landau e," Chaos, Solitons & Fractals, Elsevier, vol. 147(C).
    11. Ruoqin Zhang & Xichuan Zhao & Jinzhi Li & Di Zhou & Honglian Guo & Zhi-yuan Li & Feng Li, 2024. "Programmable photoacoustic patterning of microparticles in air," Nature Communications, Nature, vol. 15(1), pages 1-8, December.
    12. Antoine Aubret & Quentin Martinet & Jeremie Palacci, 2021. "Metamachines of pluripotent colloids," Nature Communications, Nature, vol. 12(1), pages 1-9, December.
    13. Xiao Li & Yineng Liu & Zhifang Lin & Jack Ng & C. T. Chan, 2021. "Non-Hermitian physics for optical manipulation uncovers inherent instability of large clusters," Nature Communications, Nature, vol. 12(1), pages 1-9, December.
    14. Yijie Shen & Zhensong Wan & Xing Fu & Mali Gong & Xilin Yang & Ruoyang Qi & Mali Gong, 2018. "Recent Advances on Tunable Vortex Beam Devices for Biomedical Applications," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 9(3), pages 7134-7138, September.
    15. Xiao Li & Yongyin Cao & Jack Ng, 2024. "Non-Hermitian non-equipartition theory for trapped particles," Nature Communications, Nature, vol. 15(1), pages 1-9, December.

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