IDEAS home Printed from https://ideas.repec.org/a/nat/nathum/v6y2022i9d10.1038_s41562-022-01359-x.html
   My bibliography  Save this article

Genome-wide association study of musical beat synchronization demonstrates high polygenicity

Author

Listed:
  • Maria Niarchou

    (Vanderbilt University Medical Center
    Vanderbilt University Medical Center)

  • Daniel E. Gustavson

    (Vanderbilt University Medical Center
    Vanderbilt University Medical Center)

  • J. Fah Sathirapongsasuti

    (23andMe, Inc)

  • Manuel Anglada-Tort

    (Max Planck Institute for Empirical Aesthetics)

  • Else Eising

    (Max Planck Institute for Psycholinguistics)

  • Eamonn Bell

    (Columbia University
    Durham University)

  • Evonne McArthur

    (Vanderbilt University Medical Center)

  • Peter Straub

    (Vanderbilt University Medical Center)

  • J. Devin McAuley

    (Michigan State University)

  • John A. Capra

    (University of California
    University of California)

  • Fredrik Ullén

    (Karolinska Institutet
    Max Planck Institute for Empirical Aesthetics)

  • Nicole Creanza

    (Vanderbilt University
    Vanderbilt University)

  • Miriam A. Mosing

    (Karolinska Institutet
    Max Planck Institute for Empirical Aesthetics
    University of Melbourne)

  • David A. Hinds

    (23andMe, Inc)

  • Lea K. Davis

    (Vanderbilt University Medical Center
    Vanderbilt University Medical Center
    Vanderbilt University Medical Center
    Vanderbilt University Medical Center)

  • Nori Jacoby

    (Max Planck Institute for Empirical Aesthetics)

  • Reyna L. Gordon

    (Vanderbilt University Medical Center
    Vanderbilt University Medical Center
    Vanderbilt University
    Vanderbilt University)

Abstract

Moving in synchrony to the beat is a fundamental component of musicality. Here we conducted a genome-wide association study to identify common genetic variants associated with beat synchronization in 606,825 individuals. Beat synchronization exhibited a highly polygenic architecture, with 69 loci reaching genome-wide significance (P

Suggested Citation

  • Maria Niarchou & Daniel E. Gustavson & J. Fah Sathirapongsasuti & Manuel Anglada-Tort & Else Eising & Eamonn Bell & Evonne McArthur & Peter Straub & J. Devin McAuley & John A. Capra & Fredrik Ullén & , 2022. "Genome-wide association study of musical beat synchronization demonstrates high polygenicity," Nature Human Behaviour, Nature, vol. 6(9), pages 1292-1309, September.
    • Handle: RePEc:nat:nathum:v:6:y:2022:i:9:d:10.1038_s41562-022-01359-x
    DOI: 10.1038/s41562-022-01359-x
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41562-022-01359-x
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/s41562-022-01359-x?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Andrea Ravignani & Tania Delgado & Simon Kirby, 2017. "Musical evolution in the lab exhibits rhythmic universals," Nature Human Behaviour, Nature, vol. 1(1), pages 1-7, January.
    2. Hassan S. Dashti & Samuel E. Jones & Andrew R. Wood & Jacqueline M. Lane & Vincent T. Hees & Heming Wang & Jessica A. Rhodes & Yanwei Song & Krunal Patel & Simon G. Anderson & Robin N. Beaumont & Davi, 2019. "Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates," Nature Communications, Nature, vol. 10(1), pages 1-12, December.
    3. David Adam, 2019. "The promise and peril of the new science of social genomics," Nature, Nature, vol. 574(7780), pages 618-620, October.
    4. Samuel E. Jones & Jacqueline M. Lane & Andrew R. Wood & Vincent T. Hees & Jessica Tyrrell & Robin N. Beaumont & Aaron R. Jeffries & Hassan S. Dashti & Melvyn Hillsdon & Katherine S. Ruth & Marcus A. T, 2019. "Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms," Nature Communications, Nature, vol. 10(1), pages 1-11, December.
    5. Tian Ge & Chia-Yen Chen & Yang Ni & Yen-Chen Anne Feng & Jordan W. Smoller, 2019. "Polygenic prediction via Bayesian regression and continuous shrinkage priors," Nature Communications, Nature, vol. 10(1), pages 1-10, December.
    6. Simon Haworth & Ruth Mitchell & Laura Corbin & Kaitlin H. Wade & Tom Dudding & Ashley Budu-Aggrey & David Carslake & Gibran Hemani & Lavinia Paternoster & George Davey Smith & Neil Davies & Daniel J. , 2019. "Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis," Nature Communications, Nature, vol. 10(1), pages 1-9, December.
    7. Adam J. Berinsky & Michele F. Margolis & Michael W. Sances, 2014. "Separating the Shirkers from the Workers? Making Sure Respondents Pay Attention on Self‐Administered Surveys," American Journal of Political Science, John Wiley & Sons, vol. 58(3), pages 739-753, July.
    8. Christiaan A de Leeuw & Joris M Mooij & Tom Heskes & Danielle Posthuma, 2015. "MAGMA: Generalized Gene-Set Analysis of GWAS Data," PLOS Computational Biology, Public Library of Science, vol. 11(4), pages 1-19, April.
    9. Kyoko Watanabe & Erdogan Taskesen & Arjen Bochoven & Danielle Posthuma, 2017. "Functional mapping and annotation of genetic associations with FUMA," Nature Communications, Nature, vol. 8(1), pages 1-11, December.
    10. Christiaan A. Leeuw & Sven Stringer & Ilona A. Dekkers & Tom Heskes & Danielle Posthuma, 2018. "Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure," Nature Communications, Nature, vol. 9(1), pages 1-13, December.
    11. Kerstin Lindblad-Toh & Manuel Garber & Or Zuk & Michael F. Lin & Brian J. Parker & Stefan Washietl & Pouya Kheradpour & Jason Ernst & Gregory Jordan & Evan Mauceli & Lucas D. Ward & Craig B. Lowe & Al, 2011. "A high-resolution map of human evolutionary constraint using 29 mammals," Nature, Nature, vol. 478(7370), pages 476-482, October.
    12. Andries T. Marees & Dirk J. A. Smit & Abdel Abdellaoui & Michel G. Nivard & Wim Brink & Damiaan Denys & Titus J. Galama & Karin J. H. Verweij & Eske M. Derks, 2021. "Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits," Nature Human Behaviour, Nature, vol. 5(8), pages 1065-1073, August.
    13. Abdel Abdellaoui & Karin J. H. Verweij, 2021. "Dissecting polygenic signals from genome-wide association studies on human behaviour," Nature Human Behaviour, Nature, vol. 5(6), pages 686-694, June.
    14. Chelsea L Gordon & Patrice R Cobb & Ramesh Balasubramaniam, 2018. "Recruitment of the motor system during music listening: An ALE meta-analysis of fMRI data," PLOS ONE, Public Library of Science, vol. 13(11), pages 1-19, November.
    15. Sara M. Willems & Daniel J. Wright & Felix R. Day & Katerina Trajanoska & Peter K. Joshi & John A. Morris & Amy M. Matteini & Fleur C. Garton & Niels Grarup & Nikolay Oskolkov & Anbupalam Thalamuthu &, 2017. "Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness," Nature Communications, Nature, vol. 8(1), pages 1-12, December.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Matteo Sebastianelli & Sifiso M. Lukhele & Simona Secomandi & Stacey G. Souza & Bettina Haase & Michaella Moysi & Christos Nikiforou & Alexander Hutfluss & Jacquelyn Mountcastle & Jennifer Balacco & S, 2024. "A genomic basis of vocal rhythm in birds," Nature Communications, Nature, vol. 15(1), pages 1-15, December.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Yunfeng Huang & Dora Bodnar & Chia-Yen Chen & Gabriela Sanchez-Andrade & Mark Sanderson & Jun Shi & Katherine G. Meilleur & Matthew E. Hurles & Sebastian S. Gerety & Ellen A. Tsai & Heiko Runz, 2023. "Rare genetic variants impact muscle strength," Nature Communications, Nature, vol. 14(1), pages 1-8, December.
    2. Tzu-Ting Chen & Jaeyoung Kim & Max Lam & Yi-Fang Chuang & Yen-Ling Chiu & Shu-Chin Lin & Sang-Hyuk Jung & Beomsu Kim & Soyeon Kim & Chamlee Cho & Injeong Shim & Sanghyeon Park & Yeeun Ahn & Aysu Okbay, 2024. "Shared genetic architectures of educational attainment in East Asian and European populations," Nature Human Behaviour, Nature, vol. 8(3), pages 562-575, March.
    3. Nagel, Mats, 2020. "Changing perspectives: Towards detailed phenotyping in genetics," Thesis Commons a4nz2, Center for Open Science.
    4. Mingyang Li & Xixi Dang & Yiwei Chen & Zhifan Chen & Xinyi Xu & Zhiyong Zhao & Dan Wu, 2024. "Cognitive processing speed and accuracy are intrinsically different in genetic architecture and brain phenotypes," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    5. Anders M. Fjell & Øystein Sørensen & Yunpeng Wang & Inge K. Amlien & William F. C. Baaré & David Bartrés-Faz & Lars Bertram & Carl-Johan Boraxbekk & Andreas M. Brandmaier & Ilja Demuth & Christian A. , 2023. "No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy," Nature Human Behaviour, Nature, vol. 7(11), pages 2008-2022, November.
    6. Shahram Bahrami & Kaja Nordengen & Jaroslav Rokicki & Alexey A. Shadrin & Zillur Rahman & Olav B. Smeland & Piotr P. Jaholkowski & Nadine Parker & Pravesh Parekh & Kevin S. O’Connell & Torbjørn Elvsås, 2024. "The genetic landscape of basal ganglia and implications for common brain disorders," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
    7. Yash Patel & Jean Shin & Eeva Sliz & Ariana Tang & Aniket Mishra & Rui Xia & Edith Hofer & Hema Sekhar Reddy Rajula & Ruiqi Wang & Frauke Beyer & Katrin Horn & Max Riedl & Jing Yu & Henry Völzke & Rob, 2024. "Genetic risk factors underlying white matter hyperintensities and cortical atrophy," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    8. Tuomo Hartonen & Bradley Jermy & Hanna Sõnajalg & Pekka Vartiainen & Kristi Krebs & Andrius Vabalas & Tuija Leino & Hanna Nohynek & Jonas Sivelä & Reedik Mägi & Mark Daly & Hanna M. Ollila & Lili Mila, 2023. "Nationwide health, socio-economic and genetic predictors of COVID-19 vaccination status in Finland," Nature Human Behaviour, Nature, vol. 7(7), pages 1069-1083, July.
    9. Bingxin Zhao & Yujue Li & Zirui Fan & Zhenyi Wu & Juan Shu & Xiaochen Yang & Yilin Yang & Xifeng Wang & Bingxuan Li & Xiyao Wang & Carlos Copana & Yue Yang & Jinjie Lin & Yun Li & Jason L. Stein & Joa, 2024. "Eye-brain connections revealed by multimodal retinal and brain imaging genetics," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    10. Isabelle Austin-Zimmerman & Daniel F. Levey & Olga Giannakopoulou & Joseph D. Deak & Marco Galimberti & Keyrun Adhikari & Hang Zhou & Spiros Denaxas & Haritz Irizar & Karoline Kuchenbaecker & Andrew M, 2023. "Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    11. Eva-Maria Stauffer & Richard A. I. Bethlehem & Lena Dorfschmidt & Hyejung Won & Varun Warrier & Edward T. Bullmore, 2023. "The genetic relationships between brain structure and schizophrenia," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    12. Xiaofeng Zhu & Yihe Yang & Noah Lorincz-Comi & Gen Li & Amy R. Bentley & Paul S. de Vries & Michael Brown & Alanna C. Morrison & Charles N. Rotimi & W. James Gauderman & Dabeeru C. Rao & Hugues Aschar, 2024. "An approach to identify gene-environment interactions and reveal new biological insight in complex traits," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    13. Sophie A. Riesmeijer & Zoha Kamali & Michael Ng & Dmitriy Drichel & Bram Piersma & Kerstin Becker & Thomas B. Layton & Jagdeep Nanchahal & Michael Nothnagel & Ahmad Vaez & Hans Christian Hennies & Pau, 2024. "A genome-wide association meta-analysis implicates Hedgehog and Notch signaling in Dupuytren’s disease," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    14. Zhiqiang Sha & Dick Schijven & Amaia Carrion-Castillo & Marc Joliot & Bernard Mazoyer & Simon E. Fisher & Fabrice Crivello & Clyde Francks, 2021. "The genetic architecture of structural left–right asymmetry of the human brain," Nature Human Behaviour, Nature, vol. 5(9), pages 1226-1239, September.
    15. Qiao Fan & Hengtong Li & Xiaomeng Wang & Yih-Chung Tham & Kelvin Yi Chong Teo & Masayuki Yasuda & Weng Khong Lim & Yuet Ping Kwan & Jing Xian Teo & Ching-Jou Chen & Li Jia Chen & Jeeyun Ahn & Sonia Da, 2023. "Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypes," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
    16. Gianmarco Mignogna & Caitlin E. Carey & Robbee Wedow & Nikolas Baya & Mattia Cordioli & Nicola Pirastu & Rino Bellocco & Kathryn Fiuza Malerbi & Michel G. Nivard & Benjamin M. Neale & Raymond K. Walte, 2023. "Patterns of item nonresponse behaviour to survey questionnaires are systematic and associated with genetic loci," Nature Human Behaviour, Nature, vol. 7(8), pages 1371-1387, August.
    17. Catherine M. Francis & Matthias E. Futschik & Jian Huang & Wenjia Bai & Muralidharan Sargurupremraj & Alexander Teumer & Monique M. B. Breteler & Enrico Petretto & Amanda S. R. Ho & Philippe Amouyel &, 2022. "Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities," Nature Communications, Nature, vol. 13(1), pages 1-18, December.
    18. Young Jin Kim & Sanghoon Moon & Mi Yeong Hwang & Sohee Han & Hye-Mi Jang & Jinhwa Kong & Dong Mun Shin & Kyungheon Yoon & Sung Min Kim & Jong-Eun Lee & Anubha Mahajan & Hyun-Young Park & Mark I. McCar, 2022. "The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
    19. Palwende Romuald Boua & Jean-Tristan Brandenburg & Ananyo Choudhury & Hermann Sorgho & Engelbert A. Nonterah & Godfred Agongo & Gershim Asiki & Lisa Micklesfield & Solomon Choma & Francesc Xavier Góme, 2022. "Genetic associations with carotid intima-media thickness link to atherosclerosis with sex-specific effects in sub-Saharan Africans," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
    20. Sarah Grosche & Ingo Marenholz & Jorge Esparza-Gordillo & Aleix Arnau-Soler & Erola Pairo-Castineira & Franz Rüschendorf & Tarunveer S. Ahluwalia & Catarina Almqvist & Andreas Arnold & Hansjörg Baurec, 2021. "Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4," Nature Communications, Nature, vol. 12(1), pages 1-11, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nathum:v:6:y:2022:i:9:d:10.1038_s41562-022-01359-x. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.