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Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly

Author

Listed:
  • Sushruta Surappa

    (Stanford University)

  • Suraj Pavagada

    (Stanford University)

  • Fernando Soto

    (Stanford University)

  • Demir Akin

    (Stanford University)

  • Charles Wei

    (Georgia Institute of Technology)

  • F. Levent Degertekin

    (Georgia Institute of Technology)

  • Utkan Demirci

    (Stanford University)

Abstract

Particle manipulation plays a pivotal role in scientific and technological domains such as materials science, physics, and the life sciences. Here, we present a dynamically reconfigurable acoustofluidic metasurface that enables precise trapping and positioning of microscale particles in fluidic environments. By harnessing acoustic-structure interaction in a passive membrane resonator array, we generate localized standing acoustic waves that can be reconfigured in real-time. The resulting radiation force allows for subwavelength manipulation and patterning of particles on the metasurface at individual and collective scales, with actuation frequencies below 2 MHz. We further demonstrate the capabilities of the reconfigurable metasurface in trapping and enriching beads and biological cells flowing in microfluidic channels, showcasing its potential in high-throughput bioanalytical applications. Our versatile and biocompatible particle manipulation platform is suitable for applications ranging from the assembly of colloidal particles to enrichment of rare cells.

Suggested Citation

  • Sushruta Surappa & Suraj Pavagada & Fernando Soto & Demir Akin & Charles Wei & F. Levent Degertekin & Utkan Demirci, 2025. "Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly," Nature Communications, Nature, vol. 16(1), pages 1-10, December.
    • Handle: RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-024-55337-0
    DOI: 10.1038/s41467-024-55337-0
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