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Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex

Author

Listed:
  • Demetrio Ferro

    (Universitat Pompeu Fabra
    Universitat Pompeu Fabra)

  • Tyler Cash-Padgett

    (University of Minnesota)

  • Maya Zhe Wang

    (University of Minnesota)

  • Benjamin Y. Hayden

    (Baylor College of Medicine)

  • Rubén Moreno-Bote

    (Universitat Pompeu Fabra
    Universitat Pompeu Fabra
    Universitat Pompeu Fabra)

Abstract

During economic choice, options are often considered in alternation, until commitment. Nonetheless, neuroeconomics typically ignores the dynamic aspects of deliberation. We trained two male macaques to perform a value-based decision-making task in which two risky offers were presented in sequence at the opposite sides of the visual field, each followed by a delay epoch where offers were invisible. Surprisingly, during the two delays, subjects tend to look at empty locations where the offers had previously appeared, with longer fixations increasing the probability of choosing the associated offer. Spiking activity in orbitofrontal cortex reflects the value of the gazed offer, or of the offer associated with the gazed empty spatial location, even if it is not the most recent. This reactivation reflects a reevaluation process, as fluctuations in neural spiking correlate with upcoming choice. Our results suggest that look-at-nothing gazing triggers the reactivation of a previously seen offer for further evaluation.

Suggested Citation

  • Demetrio Ferro & Tyler Cash-Padgett & Maya Zhe Wang & Benjamin Y. Hayden & Rubén Moreno-Bote, 2024. "Gaze-centered gating, reactivation, and reevaluation of economic value in orbitofrontal cortex," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-50214-2
    DOI: 10.1038/s41467-024-50214-2
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    References listed on IDEAS

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    1. Stephanie L. Grella & Amanda H. Fortin & Evan Ruesch & John H. Bladon & Leanna F. Reynolds & Abby Gross & Monika Shpokayte & Christine Cincotta & Yosif Zaki & Steve Ramirez, 2022. "Reactivating hippocampal-mediated memories during reconsolidation to disrupt fear," Nature Communications, Nature, vol. 13(1), pages 1-19, December.
    2. Sebastien Ballesta & Camillo Padoa-Schioppa, 2019. "Economic Decisions through Circuit Inhibition," Post-Print hal-04607659, HAL.
    3. Wenyi Zhang & Yang Xie & Tianming Yang, 2022. "Reward salience but not spatial attention dominates the value representation in the orbitofrontal cortex," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    4. Camillo Padoa-Schioppa & John A. Assad, 2006. "Neurons in the orbitofrontal cortex encode economic value," Nature, Nature, vol. 441(7090), pages 223-226, May.
    5. repec:cup:judgdm:v:4:y:2009:i:5:p:335-354 is not listed on IDEAS
    6. Ramon Nogueira & Juan M. Abolafia & Jan Drugowitsch & Emili Balaguer-Ballester & Maria V. Sanchez-Vives & Rubén Moreno-Bote, 2017. "Lateral orbitofrontal cortex anticipates choices and integrates prior with current information," Nature Communications, Nature, vol. 8(1), pages 1-13, April.
    7. Elena Reutskaja & Rosemarie Nagel & Colin F. Camerer & Antonio Rangel, 2011. "Search Dynamics in Consumer Choice under Time Pressure: An Eye-Tracking Study," American Economic Review, American Economic Association, vol. 101(2), pages 900-926, April.
    8. Nina Horstmann & Andrea Ahlgrimm & Andreas Glöckner, 2009. "How Distinct are Intuition and Deliberation? An Eye-Tracking Analysis of Instruction-Induced Decision Modes," Discussion Paper Series of the Max Planck Institute for Research on Collective Goods 2009_10, Max Planck Institute for Research on Collective Goods.
    9. Sébastien Ballesta & Weikang Shi & Katherine E. Conen & Camillo Padoa-Schioppa, 2020. "Values encoded in orbitofrontal cortex are causally related to economic choices," Nature, Nature, vol. 588(7838), pages 450-453, December.
    10. Maya Zhe Wang & Benjamin Y. Hayden & Sarah R. Heilbronner, 2022. "A structural and functional subdivision in central orbitofrontal cortex," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    11. David J. Foster & Matthew A. Wilson, 2006. "Reverse replay of behavioural sequences in hippocampal place cells during the awake state," Nature, Nature, vol. 440(7084), pages 680-683, March.
    12. Sébastien Ballesta & Weikang Shi & Camillo Padoa-Schioppa, 2022. "Orbitofrontal cortex contributes to the comparison of values underlying economic choices," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
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