AZGP1 in POMC neurons modulates energy homeostasis and metabolism through leptin-mediated STAT3 phosphorylation
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DOI: 10.1038/s41467-024-47684-9
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- Lin Jiang & Haoran Su & Xiaoyin Wu & Hong Shen & Min-Hyun Kim & Yuan Li & Martin G. Myers & Chung Owyang & Liangyou Rui, 2020. "Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
- Yasuhiko Minokoshi & Thierry Alquier & Noboru Furukawa & Young-Bum Kim & Anna Lee & Bingzhong Xue & James Mu & Fabienne Foufelle & Pascal Ferré & Morris J. Birnbaum & Bettina J. Stuck & Barbara B. Kah, 2004. "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus," Nature, Nature, vol. 428(6982), pages 569-574, April.
- Putianqi Wang & Ken H. Loh & Michelle Wu & Donald A. Morgan & Marc Schneeberger & Xiaofei Yu & Jingyi Chi & Christin Kosse & Damian Kim & Kamal Rahmouni & Paul Cohen & Jeffrey Friedman, 2020. "A leptin–BDNF pathway regulating sympathetic innervation of adipose tissue," Nature, Nature, vol. 583(7818), pages 839-844, July.
- Seul Ki Kim & Le Trung Tran & Cherl NamKoong & Hyung Jin Choi & Hye Jin Chun & Yong-ho Lee & MyungHyun Cheon & ChiHye Chung & Junmo Hwang & Hyun-Ho Lim & Dong Min Shin & Yun-Hee Choi & Ki Woo Kim, 2023. "Author Correction: Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons," Nature Communications, Nature, vol. 14(1), pages 1-1, December.
- Su Yang & Huiming Yang & Renbao Chang & Peng Yin & Yang Yang & Weili Yang & Shanshan Huang & Marta A. Gaertig & Shihua Li & Xiao-Jiang Li, 2017. "MANF regulates hypothalamic control of food intake and body weight," Nature Communications, Nature, vol. 8(1), pages 1-16, December.
- Seul Ki Kim & Le Trung Tran & Cherl NamKoong & Hyung Jin Choi & Hye Jin Chun & Yong-ho Lee & MyungHyun Cheon & ChiHye Chung & Junmo Hwang & Hyun-Ho Lim & Dong Min Shin & Yun-Hee Choi & Ki Woo Kim, 2023. "Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- G. J. Morton & D. E. Cummings & D. G. Baskin & G. S. Barsh & M. W. Schwartz, 2006. "Central nervous system control of food intake and body weight," Nature, Nature, vol. 443(7109), pages 289-295, September.
- Yuan Fang & Zhi-Yong Shen & Yi-Zhi Zhan & Xiao-Chuang Feng & Ke-Li Chen & Yong-Sheng Li & Hai-Jun Deng & Su-Ming Pan & De-Hua Wu & Yi Ding, 2019. "CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis," Nature Communications, Nature, vol. 10(1), pages 1-16, December.
- Hongli Li & Yuanzhong Xu & Yanyan Jiang & Zhiying Jiang & Joshua Otiz-Guzman & Jessie C. Morrill & Jing Cai & Zhengmei Mao & Yong Xu & Benjamin R. Arenkiel & Cheng Huang & Qingchun Tong, 2023. "The melanocortin action is biased toward protection from weight loss in mice," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
- Lin Jiang & Haoran Su & Xiaoyin Wu & Hong Shen & Min-Hyun Kim & Yuan Li & Martin G. Myers & Chung Owyang & Liangyou Rui, 2020. "Author Correction: Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease," Nature Communications, Nature, vol. 11(1), pages 1-1, December.
- Michael A. Cowley & James L. Smart & Marcelo Rubinstein & Marcelo G. Cerdán & Sabrina Diano & Tamas L. Horvath & Roger D. Cone & Malcolm J. Low, 2001. "Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus," Nature, Nature, vol. 411(6836), pages 480-484, May.
- Linghai Yang & G. Stanley McKnight, 2015. "Hypothalamic PKA regulates leptin sensitivity and adiposity," Nature Communications, Nature, vol. 6(1), pages 1-11, November.
- Jie Xu & Christopher L. Bartolome & Cho Shing Low & Xinchi Yi & Cheng-Hao Chien & Peng Wang & Dong Kong, 2018. "Genetic identification of leptin neural circuits in energy and glucose homeostases," Nature, Nature, vol. 556(7702), pages 505-509, April.
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