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Bionic artificial skin with a fully implantable wireless tactile sensory system for wound healing and restoring skin tactile function

Author

Listed:
  • Kyowon Kang

    (Yonsei University)

  • Seongryeol Ye

    (Korea Institute of Science and Technology (KIST)
    Seoul National University)

  • Chanho Jeong

    (Sungkyunkwan University (SKKU))

  • Jinmo Jeong

    (Korea Institute of Science and Technology
    The University of Texas at Austin)

  • Yeong-sinn Ye

    (Sungkyunkwan University (SKKU))

  • Jin-Young Jeong

    (Korea Institute of Science and Technology)

  • Yu-Jin Kim

    (Korea Institute of Science and Technology (KIST))

  • Selin Lim

    (Yonsei University
    YU-KIST Institute, Yonsei University)

  • Tae Hee Kim

    (Korea Institute of Science and Technology (KIST)
    Seoul National University Hospital)

  • Kyung Yeun Kim

    (Korea Institute of Science and Technology
    Seoul National University)

  • Jong Uk Kim

    (Northwestern University)

  • Gwan In Kim

    (Yonsei University
    University of Illinois Urbana-Champaign)

  • Do Hoon Chun

    (Yonsei University)

  • Kiho Kim

    (Yonsei University)

  • Jaejin Park

    (Yonsei University)

  • Jung-Hoon Hong

    (Yonsei University)

  • Byeonghak Park

    (Stanford University)

  • Kyubeen Kim

    (Yonsei University)

  • Sujin Jung

    (Yonsei University)

  • Kyeongrim Baek

    (Yonsei University)

  • Dongjun Cho

    (Yonsei University)

  • Jin Yoo

    (Korea Institute of Science and Technology (KIST))

  • Kangwon Lee

    (Seoul National University
    Seoul National University)

  • Huanyu Cheng

    (The Pennsylvania State University)

  • Byung-Wook Min

    (Yonsei University)

  • Hyun Jae Kim

    (Yonsei University)

  • Hojeong Jeon

    (Korea Institute of Science and Technology
    Korea University)

  • Hyunjung Yi

    (Korea Institute of Science and Technology
    YU-KIST Institute, Yonsei University)

  • Tae-il Kim

    (Sungkyunkwan University (SKKU))

  • Ki Jun Yu

    (Yonsei University
    YU-KIST Institute, Yonsei University)

  • Youngmee Jung

    (Korea Institute of Science and Technology (KIST)
    YU-KIST Institute, Yonsei University)

Abstract

Tactile function is essential for human life as it enables us to recognize texture and respond to external stimuli, including potential threats with sharp objects that may result in punctures or lacerations. Severe skin damage caused by severe burns, skin cancer, chemical accidents, and industrial accidents damage the structure of the skin tissue as well as the nerve system, resulting in permanent tactile sensory dysfunction, which significantly impacts an individual’s daily life. Here, we introduce a fully-implantable wireless powered tactile sensory system embedded artificial skin (WTSA), with stable operation, to restore permanently damaged tactile function and promote wound healing for regenerating severely damaged skin. The fabricated WTSA facilitates (i) replacement of severely damaged tactile sensory with broad biocompatibility, (ii) promoting of skin wound healing and regeneration through collagen and fibrin-based artificial skin (CFAS), and (iii) minimization of foreign body reaction via hydrogel coating on neural interface electrodes. Furthermore, the WTSA shows a stable operation as a sensory system as evidenced by the quantitative analysis of leg movement angle and electromyogram (EMG) signals in response to varying intensities of applied pressures.

Suggested Citation

  • Kyowon Kang & Seongryeol Ye & Chanho Jeong & Jinmo Jeong & Yeong-sinn Ye & Jin-Young Jeong & Yu-Jin Kim & Selin Lim & Tae Hee Kim & Kyung Yeun Kim & Jong Uk Kim & Gwan In Kim & Do Hoon Chun & Kiho Kim, 2024. "Bionic artificial skin with a fully implantable wireless tactile sensory system for wound healing and restoring skin tactile function," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
  • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-023-44064-7
    DOI: 10.1038/s41467-023-44064-7
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