Single-molecule FRET unmasks structural subpopulations and crucial molecular events during FUS low-complexity domain phase separation
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DOI: 10.1038/s41467-023-43225-y
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- Miao Yu & Maziar Heidari & Sofya Mikhaleva & Piau Siong Tan & Sara Mingu & Hao Ruan & Christopher D. Reinkemeier & Agnieszka Obarska-Kosinska & Marc Siggel & Martin Beck & Gerhard Hummer & Edward A. L, 2023. "Visualizing the disordered nuclear transport machinery in situ," Nature, Nature, vol. 617(7959), pages 162-169, May.
- Michele Vendruscolo & Monika Fuxreiter, 2022. "Protein condensation diseases: therapeutic opportunities," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
- Taranpreet Kaur & Muralikrishna Raju & Ibraheem Alshareedah & Richoo B. Davis & Davit A. Potoyan & Priya R. Banerjee, 2021. "Sequence-encoded and composition-dependent protein-RNA interactions control multiphasic condensate morphologies," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
- Aishwarya Agarwal & Lisha Arora & Sandeep K. Rai & Anamika Avni & Samrat Mukhopadhyay, 2022. "Spatiotemporal modulations in heterotypic condensates of prion and α-synuclein control phase transitions and amyloid conversion," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
- Anamika Avni & Ashish Joshi & Anuja Walimbe & Swastik G. Pattanashetty & Samrat Mukhopadhyay, 2022. "Single-droplet surface-enhanced Raman scattering decodes the molecular determinants of liquid-liquid phase separation," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
- Benjamin Schuler & Everett A. Lipman & William A. Eaton, 2002. "Probing the free-energy surface for protein folding with single-molecule fluorescence spectroscopy," Nature, Nature, vol. 419(6908), pages 743-747, October.
- Nicola Galvanetto & Miloš T. Ivanović & Aritra Chowdhury & Andrea Sottini & Mark F. Nüesch & Daniel Nettels & Robert B. Best & Benjamin Schuler, 2023. "Extreme dynamics in a biomolecular condensate," Nature, Nature, vol. 619(7971), pages 876-883, July.
- Myungwoon Lee & Ujjayini Ghosh & Kent R. Thurber & Masato Kato & Robert Tycko, 2020. "Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS," Nature Communications, Nature, vol. 11(1), pages 1-14, December.
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- Ashish Joshi & Anuja Walimbe & Snehasis Sarkar & Lisha Arora & Gaganpreet Kaur & Prince Jhandai & Dhruba Chatterjee & Indranil Banerjee & Samrat Mukhopadhyay, 2024. "Intermolecular energy migration via homoFRET captures the modulation in the material property of phase-separated biomolecular condensates," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
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