The mRNA methyltransferase Mettl3 modulates cytokine mRNA stability and limits functional responses in mast cells
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-023-39614-y
Download full text from publisher
References listed on IDEAS
- Anthony Khong & Tyler Matheny & Thao Ngoc Huynh & Vincent Babl & Roy Parker, 2022. "Limited effects of m6A modification on mRNA partitioning into stress granules," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
- Huilong Yin & Xiang Zhang & Pengyuan Yang & Xiaofang Zhang & Yingran Peng & Da Li & Yanping Yu & Ye Wu & Yidi Wang & Jinbao Zhang & Xiaochen Ding & Xiangpeng Wang & Angang Yang & Rui Zhang, 2021. "RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
- Nian Liu & Qing Dai & Guanqun Zheng & Chuan He & Marc Parisien & Tao Pan, 2015. "N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions," Nature, Nature, vol. 518(7540), pages 560-564, February.
- Baixing Wu & Shichen Su & Deepak P. Patil & Hehua Liu & Jianhua Gan & Samie R. Jaffrey & Jinbiao Ma, 2018. "Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
- Eliza Yankova & Wesley Blackaby & Mark Albertella & Justyna Rak & Etienne Braekeleer & Georgia Tsagkogeorga & Ewa S. Pilka & Demetrios Aspris & Dan Leggate & Alan G. Hendrick & Natalie A. Webster & By, 2021. "Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia," Nature, Nature, vol. 593(7860), pages 597-601, May.
- Hua-Bing Li & Jiyu Tong & Shu Zhu & Pedro J. Batista & Erin E. Duffy & Jun Zhao & Will Bailis & Guangchao Cao & Lina Kroehling & Yuanyuan Chen & Geng Wang & James P. Broughton & Y. Grace Chen & Yuval , 2017. "m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways," Nature, Nature, vol. 548(7667), pages 338-342, August.
- Huamin Wang & Xiang Hu & Mingyan Huang & Juan Liu & Yan Gu & Lijia Ma & Qi Zhou & Xuetao Cao, 2019. "Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation," Nature Communications, Nature, vol. 10(1), pages 1-12, December.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Xiao Han & Lijuan Liu & Saihua Huang & Wenfeng Xiao & Yajing Gao & Weitao Zhou & Caiyan Zhang & Hongmei Zheng & Lan Yang & Xueru Xie & Qiuyan Liang & Zikun Tu & Hongmiao Yu & Jinrong Fu & Libo Wang & , 2023. "RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis," Nature Communications, Nature, vol. 14(1), pages 1-20, December.
- Xiang Zhang & Huilong Yin & Xiaofang Zhang & Xunliang Jiang & Yongkang Liu & Haolin Zhang & Yingran Peng & Da Li & Yanping Yu & Jinbao Zhang & Shuli Cheng & Angang Yang & Rui Zhang, 2022. "N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
- Ainara González-Iglesias & Aida Arcas & Ana Domingo-Muelas & Estefania Mancini & Joan Galcerán & Juan Valcárcel & Isabel Fariñas & M. Angela Nieto, 2024. "Intron detention tightly regulates the stemness/differentiation switch in the adult neurogenic niche," Nature Communications, Nature, vol. 15(1), pages 1-18, December.
- Yan Xu & Zhuowei Zhou & Xinmei Kang & Lijie Pan & Chang Liu & Xiaoqi Liang & Jiajie Chu & Shuai Dong & Yanli Li & Qiuli Liu & Yuetong Sun & Shanshan Yu & Qi Zhang, 2022. "Mettl3-mediated mRNA m6A modification controls postnatal liver development by modulating the transcription factor Hnf4a," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Chen Wang & Hideki Tanizawa & Connor Hill & Aaron Havas & Qiang Zhang & Liping Liao & Xue Hao & Xue Lei & Lu Wang & Hao Nie & Yuan Qi & Bin Tian & Alessandro Gardini & Andrew V. Kossenkov & Aaron Gold, 2024. "METTL3-mediated chromatin contacts promote stress granule phase separation through metabolic reprogramming during senescence," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
- Jasmin Bartl & Marco Zanini & Flavia Bernardi & Antoine Forget & Lena Blümel & Julie Talbot & Daniel Picard & Nan Qin & Gabriele Cancila & Qingsong Gao & Soumav Nath & Idriss Mahoungou Koumba & Mariet, 2022. "The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Xiaochuan Liu & Hao Chen & Zekun Li & Xiaoxiao Yang & Wen Jin & Yuting Wang & Jian Zheng & Long Li & Chenghao Xuan & Jiapei Yuan & Yang Yang, 2024. "InPACT: a computational method for accurate characterization of intronic polyadenylation from RNA sequencing data," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
- Qiang Luo & Jiezhen Mo & Hao Chen & Zetao Hu & Baihui Wang & Jiabing Wu & Ziyu Liang & Wenhao Xie & Kangxi Du & Maolin Peng & Yingping Li & Tianyang Li & Yangyi Zhang & Xiaoyan Shi & Wen-Hui Shen & Ya, 2022. "Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4," Nature Communications, Nature, vol. 13(1), pages 1-11, December.
- Katja Hartstock & Nadine A. Kueck & Petr Spacek & Anna Ovcharenko & Sabine Hüwel & Nicolas V. Cornelissen & Amarnath Bollu & Christoph Dieterich & Andrea Rentmeister, 2023. "MePMe-seq: antibody-free simultaneous m6A and m5C mapping in mRNA by metabolic propargyl labeling and sequencing," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
- Gaia Timoteo & Andrea Giuliani & Adriano Setti & Martina C. Biagi & Michela Lisi & Tiziana Santini & Alessia Grandioso & Davide Mariani & Francesco Castagnetti & Eleonora Perego & Sabrina Zappone & Se, 2024. "M6A reduction relieves FUS-associated ALS granules," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
- Kristin A. Fluke & Ryan T. Fuchs & Yueh-Lin Tsai & Victoria Talbott & Liam Elkins & Hallie P. Febvre & Nan Dai & Eric J. Wolf & Brett W. Burkhart & Jackson Schiltz & G. Brett Robb & Ivan R. Corrêa & T, 2024. "The extensive m5C epitranscriptome of Thermococcus kodakarensis is generated by a suite of RNA methyltransferases that support thermophily," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Adrien Leger & Paulo P. Amaral & Luca Pandolfini & Charlotte Capitanchik & Federica Capraro & Valentina Miano & Valentina Migliori & Patrick Toolan-Kerr & Theodora Sideri & Anton J. Enright & Konstant, 2021. "RNA modifications detection by comparative Nanopore direct RNA sequencing," Nature Communications, Nature, vol. 12(1), pages 1-17, December.
- Elzbieta Kierzek & Xiaoju Zhang & Richard M. Watson & Scott D. Kennedy & Marta Szabat & Ryszard Kierzek & David H. Mathews, 2022. "Secondary structure prediction for RNA sequences including N6-methyladenosine," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
- Yinliang Zhang & Chunyuan Du & Wei Wang & Wei Qiao & Yuhui Li & Yujie Zhang & Sufang Sheng & Xuenan Zhou & Lei Zhang & Heng Fan & Ying Yu & Yong Chen & Yunfei Liao & Shihong Chen & Yongsheng Chang, 2024. "Glucocorticoids increase adiposity by stimulating Krüppel-like factor 9 expression in macrophages," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Wen-Lan Yang & Weinan Qiu & Ting Zhang & Kai Xu & Zi-Juan Gu & Yu Zhou & Heng-Ji Xu & Zhong-Zhou Yang & Bin Shen & Yong-Liang Zhao & Qi Zhou & Ying Yang & Wei Li & Peng-Yuan Yang & Yun-Gui Yang, 2023. "Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
- Weiwei Dai & Ruotong Tian & Liubing Yu & Shasha Bian & Yuling Chen & Bowen Yin & Yuxuan Luan & Siqi Chen & Zhuoyang Fan & Rucheng Yan & Xin Pan & Yingyong Hou & Rong Li & Juxiang Chen & Minfeng Shu, 2024. "Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
- Yuanpei Li & Xiaoniu He & Xiao Lu & Zhicheng Gong & Qing Li & Lei Zhang & Ronghui Yang & Chengyi Wu & Jialiang Huang & Jiancheng Ding & Yaohui He & Wen Liu & Ceshi Chen & Bin Cao & Dawang Zhou & Yufen, 2022. "METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions," Nature Communications, Nature, vol. 13(1), pages 1-23, December.
- Debjit Khan & Iyappan Ramachandiran & Kommireddy Vasu & Arnab China & Krishnendu Khan & Fabio Cumbo & Dalia Halawani & Fulvia Terenzi & Isaac Zin & Briana Long & Gregory Costain & Susan Blaser & Amand, 2024. "Homozygous EPRS1 missense variant causing hypomyelinating leukodystrophy-15 alters variant-distal mRNA m6A site accessibility," Nature Communications, Nature, vol. 15(1), pages 1-24, December.
- Zhiyuan Luo & Qilian Ma & Shan Sun & Ningning Li & Hongfeng Wang & Zheng Ying & Shengdong Ke, 2023. "Exon-intron boundary inhibits m6A deposition, enabling m6A distribution hallmark, longer mRNA half-life and flexible protein coding," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Xiao-Lan Zhang & Xin-Hui Chen & Binwu Xu & Min Chen & Song Zhu & Nan Meng & Ji-Zhong Wang & Huifang Zhu & De Chen & Jin-Bao Liu & Guang-Rong Yan, 2023. "K235 acetylation couples with PSPC1 to regulate the m6A demethylation activity of ALKBH5 and tumorigenesis," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-39614-y. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.