IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v13y2022i1d10.1038_s41467-022-29804-5.html
   My bibliography  Save this article

Molecular communications in complex systems of dynamic supramolecular polymers

Author

Listed:
  • Martina Crippa

    (Politecnico di Torino)

  • Claudio Perego

    (University of Applied Sciences and Arts of Southern Switzerland, Polo Universitario Lugano)

  • Anna L. Marco

    (University of Applied Sciences and Arts of Southern Switzerland, Polo Universitario Lugano
    Università degli Studi di Genova)

  • Giovanni M. Pavan

    (Politecnico di Torino
    University of Applied Sciences and Arts of Southern Switzerland, Polo Universitario Lugano)

Abstract

Supramolecular polymers are composed of monomers that self-assemble non-covalently, generating distributions of monodimensional fibres in continuous communication with each other and with the surrounding solution. Fibres, exchanging molecular species, and external environment constitute a sole complex system, which intrinsic dynamics is hard to elucidate. Here we report coarse-grained molecular simulations that allow studying supramolecular polymers at the thermodynamic equilibrium, explicitly showing the complex nature of these systems, which are composed of exquisitely dynamic molecular entities. Detailed studies of molecular exchange provide insights into key factors controlling how assemblies communicate with each other, defining the equilibrium dynamics of the system. Using minimalistic and finer chemically relevant molecular models, we observe that a rich concerted complexity is intrinsic in such self-assembling systems. This offers a new dynamic and probabilistic (rather than structural) picture of supramolecular polymer systems, where the travelling molecular species continuously shape the assemblies that statistically emerge at the equilibrium.

Suggested Citation

  • Martina Crippa & Claudio Perego & Anna L. Marco & Giovanni M. Pavan, 2022. "Molecular communications in complex systems of dynamic supramolecular polymers," Nature Communications, Nature, vol. 13(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-29804-5
    DOI: 10.1038/s41467-022-29804-5
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-022-29804-5
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-022-29804-5?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Peter A. Korevaar & Subi J. George & Albert J. Markvoort & Maarten M. J. Smulders & Peter A. J. Hilbers & Albert P. H. J. Schenning & Tom F. A. De Greef & E. W. Meijer, 2012. "Pathway complexity in supramolecular polymerization," Nature, Nature, vol. 481(7382), pages 492-496, January.
    2. Matthew B. Baker & Lorenzo Albertazzi & Ilja K. Voets & Christianus M.A. Leenders & Anja R.A. Palmans & Giovanni M. Pavan & E.W. Meijer, 2015. "Consequences of chirality on the dynamics of a water-soluble supramolecular polymer," Nature Communications, Nature, vol. 6(1), pages 1-12, May.
    3. Mattia Marenda & Enzo Orlandini & Cristian Micheletti, 2018. "Discovering privileged topologies of molecular knots with self-assembling models," Nature Communications, Nature, vol. 9(1), pages 1-8, December.
    4. Xianwen Lou & René P. M. Lafleur & Christianus M. A. Leenders & Sandra M. C. Schoenmakers & Nicholas M. Matsumoto & Matthew B. Baker & Joost L. J. van Dongen & Anja R. A. Palmans & E W Meijer, 2017. "Dynamic diversity of synthetic supramolecular polymers in water as revealed by hydrogen/deuterium exchange," Nature Communications, Nature, vol. 8(1), pages 1-8, August.
    5. Mohit Kumar & Patrick Brocorens & Claire Tonnelé & David Beljonne & Mathieu Surin & Subi J. George, 2014. "A dynamic supramolecular polymer with stimuli-responsive handedness for in situ probing of enzymatic ATP hydrolysis," Nature Communications, Nature, vol. 5(1), pages 1-8, December.
    6. Elisabeth Weyandt & Luigi Leanza & Riccardo Capelli & Giovanni M. Pavan & Ghislaine Vantomme & E. W. Meijer, 2022. "Controlling the length of porphyrin supramolecular polymers via coupled equilibria and dilution-induced supramolecular polymerization," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    7. Ananya Mishra & Divya B. Korlepara & Mohit Kumar & Ankit Jain & Narendra Jonnalagadda & Karteek K. Bejagam & Sundaram Balasubramanian & Subi J. George, 2018. "Biomimetic temporal self-assembly via fuel-driven controlled supramolecular polymerization," Nature Communications, Nature, vol. 9(1), pages 1-9, December.
    8. Albert J. Markvoort & Huub M.M. ten Eikelder & Peter A.J. Hilbers & Tom F.A. de Greef & E.W. Meijer, 2011. "Theoretical models of nonlinear effects in two-component cooperative supramolecular copolymerizations," Nature Communications, Nature, vol. 2(1), pages 1-9, September.
    9. Davide Bochicchio & Matteo Salvalaglio & Giovanni M. Pavan, 2017. "Into the Dynamics of a Supramolecular Polymer at Submolecular Resolution," Nature Communications, Nature, vol. 8(1), pages 1-11, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ty Christoff-Tempesta & Yukio Cho & Samuel J. Kaser & Linnaea D. Uliassi & Xiaobing Zuo & Shayna L. Hilburg & Lilo D. Pozzo & Julia H. Ortony, 2024. "Interfacial dynamics mediate surface binding events on supramolecular nanostructures," Nature Communications, Nature, vol. 15(1), pages 1-8, December.
    2. Michael D. Dore & Muhammad Ghufran Rafique & Tianxiao Peter Yang & Marlo Zorman & Casey M. Platnich & Pengfei Xu & Tuan Trinh & Felix J. Rizzuto & Gonzalo Cosa & Jianing Li & Alba Guarné & Hanadi F. S, 2024. "Heat-activated growth of metastable and length-defined DNA fibers expands traditional polymer assembly," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    3. Jingjing Li & Yihan Cui & Yi-Lin Lu & Yunfei Zhang & Kaihuang Zhang & Chaonan Gu & Kaifang Wang & Yujia Liang & Chun-Sen Liu, 2023. "Programmable supramolecular chirality in non-equilibrium systems affording a multistate chiroptical switch," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
    4. Song-Meng Wang & Yan-Fang Wang & Liping Huang & Li-Shuo Zheng & Hao Nian & Yu-Tao Zheng & Huan Yao & Wei Jiang & Xiaoping Wang & Liu-Pan Yang, 2023. "Chiral recognition of neutral guests by chiral naphthotubes with a bis-thiourea endo-functionalized cavity," Nature Communications, Nature, vol. 14(1), pages 1-9, December.
    5. Shixin Fa & Tan-hao Shi & Suzu Akama & Keisuke Adachi & Keisuke Wada & Seigo Tanaka & Naoki Oyama & Kenichi Kato & Shunsuke Ohtani & Yuuya Nagata & Shigehisa Akine & Tomoki Ogoshi, 2022. "Real-time chirality transfer monitoring from statistically random to discrete homochiral nanotubes," Nature Communications, Nature, vol. 13(1), pages 1-10, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-29804-5. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.